scholarly journals Infección metastásica por Staphylococcus aureus en neonatos: a propósito de un caso

Bionatura ◽  
2021 ◽  
Vol 3 (3) ◽  
pp. 2038-2042
Author(s):  
Laura Taylor ◽  
Carlos S. Mamani-García ◽  
Alexandra Gutiérrez-Pingo ◽  
Jerry K. Benites-Meza ◽  
Diego Chambergo-Michilot ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Neonatal Intensive Care ◽  
Distress Syndrome ◽  
Premature Neonate ◽  
Bacterial Sepsis ◽  
Premature Rupture ◽  
E Coli ◽  
Staphylococcus Aureus Bacteremia ◽  
Metastatic Infection ◽  
Neonatal Respiratory Distress

Metastatic infection as an infrequent complication of Staphylococcus aureus bacteremia in neonates is challenging due to the limited literature. To report the clinical case of a premature neonate who developed a metastatic infection as a complication of S. aureus bacteremia. We present the case of a premature neonate admitted to the Neonatal Intensive Care Unit, diagnosed with bacterial sepsis, neonatal respiratory distress syndrome, and involvement by premature rupture of the membrane. A patch catheter was inserted, and he was successfully treated for E. coli bacteremia. He was re-admitted for late sepsis due to infection with multi-sensitive S. aureus in a patch catheter. An abscess appears on the front of the chest due to S. aureus, confirming metastatic infection. The abscess was drained with a favorable resolution of the clinical picture. In neonates submitted to invasive procedures, it is essential to monitor the clinical evolution and early identification of metastatic infection after Staphylococcus aureus bacteremia and provide early treatment to avoid sequelae.

scholarly journals 1056. Predicting Central Nervous System Complications in Staphylococcus aureus Bacteremia Using Clinical Scoring System

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S315-S316
Author(s):  
Chung-Jong Kim ◽  
Kyoung-Ho Song ◽  
Chang Kyung Kang ◽  
Pyeong Gyun Choe ◽  
Ji Yun Bae ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Staphylococcus Aureus ◽  
Nervous System ◽  
Risk Factor ◽  
Predictive Value ◽  
Brain Mri ◽  
Multivariate Logistic Regression Analysis ◽  
Staphylococcus Aureus Bacteremia ◽  
Metastatic Infection ◽  
Clinical Scoring

Abstract Background Central nervous system (CNS) complications occurring in patients with Staphylococcus aureus bacteremia (SAB) are the most severe complications. In this study, we compared clinical data of SAB patients between cases with and without CNS complication and analyzed the risk factor of CNS complications. Methods Data from cases with SAB occurred during 5 years at four hospitals were collected. The presence of CNS complications was confirmed by brain MRI, CT, or lumbar puncture. We excluded the cases who already had CNS lesions such as trauma, brain tumor, or cerebrovascular accident. We also excluded the cases who were died or transfer out <7 days of bacteremia onset. Cases were divided into complication group or noncomplication group according to the presence of CNS complication. We compared the clinical profiles between the groups, and analyzed the risk factor of CNS complications by multivariate logistic regression analysis. Results A total of 1,085 cases of SAB patients were included. Among these, 43 (4%) cases were complication group (embolic infarct [n = 23], brain hemorrhage [n = 8], infarct with hemorrhage [n = 8], and brain abscess or meningitis [n = 4]), while 810 (74%) cases were noncomplication group. Two hundred and forty-one cases were excluded. The results of multivariate analysis were shown in table. When selecting by having less than three factors among SOFA > 5, methicillin-susceptible, endovascular infection (weight 2), presence of metastatic infection and community onset, it helps to exclude CNS complications (AUC of ROC curve = 0.77, P < 0.01, sensitivity; 67.5%, specificity: 75.5%, positive predictive value: 12.9%, negative predictive value 97.7%). Conclusion CNS complication could be excluded by using clinical variables Disclosures All authors: No reported disclosures.

scholarly journals Because of nasal carriage of Staphylococcus aureus Bacteremia in Neonatal Intensive Care Unit

2016 ◽  
Vol 6 (4) ◽  
pp. 382-382
Author(s):  
Rezan Harman ◽  
Özgür Günal ◽  
Ünal Sarıkabadayı ◽  
Abdulkadir Daldal ◽  
Elif Özdemir ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Nasal Carriage ◽  
Staphylococcus Aureus Bacteremia

Management of an Early Onset Sepsis with COVID19 in a Premature Neonate - A Case Report

2021 ◽  
Author(s):  
Mahbod Kaveh ◽  
seyyed Mohsen sadatinejad
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Intensive Care ◽  
Respiratory Distress ◽  
Neonatal Intensive Care ◽  
Distress Syndrome ◽  
Current Knowledge ◽  
Premature Neonate ◽  
Nasopharyngeal Swab ◽  
Medical Specialties ◽  
Early Onset Sepsis

Abstract Background: neonates appear to be less affected by COVID-19 than adults. The overall challenge has been for all medical specialties, including neonatal intensive care. Unfortunately, current knowledge about severe acute respiratory distress syndrome of coronavirus 2 (SARS-CoV-2) infection is limited. Case presentation: In this report, we present an ill premature neonate who were born from mother with negative nasopharyngeal swab test for SARS-COV-2. On the 5th day of life, baby developed respiratory distress. Nasopharyngeal swab test for SARS-COV-2 was positive. Intubation and intratracheal surfactant was implemented. Patient was treated with Intravenous immunoglobulin and corticosteroid over a period of 14 days. Conclusion: The basis of treatment in neonatal covid19 is supportive care. Some studies have treated infants with various drugs such as Hydroxychloroquine, Favipiravir, and Remedsivir. In our case, we used corticosteroids and IVIg to treat a 5-day-old baby. We got good results after 2 weeks of treatment with dexamethasone 0.3 mg / kg per day and 2 g / kg IVIg (in three divided doses). It seems that these treatments, along with adjuvant ventilation and the use of endotracheal surfactants, can improve the patient's general condition.

scholarly journals Sensitivitas Bakteri Penyebab Sepsis Neonatorum terhadap Meropenem di Neonatal Intensive Care Unit dan Perinatologi RSUP DR M Djamil Padang Padang Tahun 2012

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Susan Insani Putri ◽  
Aziz Djamal ◽  
Rahmatini Rahmatini
Keyword(s):  
Intensive Care Unit ◽  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Broad Spectrum ◽  
Proteus Mirabilis ◽  
Neonatal Intensive Care ◽  
Cross Sectional ◽  
E Coli ◽  
Early Onset Sepsis

AbstrakSepsis neonatorum merupakan salah satu penyebab kematian terbanyak pada neonatus. Manifestasi klinis sepsis neonatorum stadium dini tidak spesifik sehingga sulit dibedakan dari masalah neonatus lainnya. Meropenem merupakan antibiotika lini ketiga dengan ultra broad spectrum. Meropenem banyak digunakan dibeberapa instalasi RSUP DR M Djamil Padang terutama di bagian perinatologi dan Neonatal Intensive Care Unit (NICU) untuk mengobati infeksi berat seperti sepsis. Penelitian ini telah dilaksanakan pada bulan Juni 2013 sampai Desember 2013 di bagian Rekam Medik RSUP DR M Djamil Padang. Tujuannya untuk mengetahui bakteri penyebab sepsis neonatorum serta sensitivitasnya terhadap meropenem. Penelitian ini merupakan studi deskriptif yang bersifat cross-sectional. Dari hasil penelitian ditemukan bakteri penyebab sepsis neonatorum adalah Klebsiella sp. (79.2%) diikuti oleh Staphylococcus aureus dan Pseudomonas aerogenosa masing-masing sebanyak (5.7%), E. coli sebanyak (3.8%), Proteus mirabilis, Staphylococcus epidermidis serta Streptococcus alfa hemoliticus masing-masing (1.9%). Persentase sensitivitas bakteri penyebab sepsis neonatorum terhadap meropenem sebesar 77.4%. Disimpulkan bahwa bakteri penyebab terbanyak pada sepsis neonatorum adalah Klebsiella sp dan sensitivitas bakteri terhadap meropenem masih baik.Kata kunci: Sepsis neonatorum, bakteri penyebab, meropenemAbstractSepsis neonatorum is one of the diseases that cause the highest number of deaths in neonatal period. Because clinical manifestations of early onset sepsis neonatorum is not specific, it is quite difficult to differentiate it from other neonatal problems. Meropenem is a third line antibiotics with ultra-broad spectrum. It is widely used in many installations at RSUP DR M. Djamil especially in the section of perinatology and Neonatal Intensive Care Unit (NICU) to treat severe infections such as sepsis. This research was conducted from June 2013 until December 2013 at Medical Record Section of RSUP DR M. Djamil Padang. The goal of this research is to discover which bacterium causes sepsis neonatorum and its sensitivity to meropenem. This research is a cross-sectional descriptive study. According to the research result, bacteria that cause sepsis neonatorum are Klebsiella sp. (79.2%), Staphylococcus aureus (5.7%), Pseudomonas aerogenosa (5.7%), E. coli (3.8%), Proteus mirabilis (1.9%), Staphylococcus epidermis (1.9%) and Streptococcus alfa hemoliticus (1.9%). These bacteria has 77.4% sensitivity to meropenem. It can be concluded that the bacteria which cause the highest number of sepsis neonatorum cases is Klebsiella sp. and still has good sensitivity to meropenem.Keyword: Sepsis neonatorum, bacteria, meropenem

Untersuchungen zur aeroben bakteriellen Besiedlung der Vaginalschleimhaut klinisch gesunder Kätzinnen

2004 ◽  
Vol 32 (02) ◽  
pp. 88-91
Author(s):  
Susanne Kloß ◽  
A. Wehrend ◽  
Astrid König ◽  
H. Bostedt
Keyword(s):  
Staphylococcus Aureus ◽  
Staphylococcus Epidermidis ◽  
Pasteurella Multocida ◽  
E Coli ◽  
Klinische Relevanz ◽  
Staphylococcus Intermedius

Zusammenfassung: Gegenstand und Ziel: Im Gegensatz zur Hündin liegen bei der Katze bisher wenige Studien über die genitale Keimflora geschlechtsgesunder Tiere vor. Ziel der Untersuchung war daher, physiologische Daten über die aerobe Vaginalflora bei dieser Spezies zu gewinnen. Material und Methoden: Für die vorliegende Studie standen 26 gesunde, anöstrische Katzen zur Verfügung, die zu einer Ovariohysterektomie vorgestellt wurden. Nach einer klinischen Untersuchung wurden von allen Probanden unter sterilen Bedingungen Vaginaltupfer entnommen. Ergebnisse: In allen Proben konnte ein Bakterienwachstum mit durchschnittlich zwei verschiedenen Bakterienspezies nachgewiesen werden. Die Gesamtkeimgehalte wurden bei 50% der Vaginaltupferproben als gering-, bei 15% als mittel- und bei 35% als hochgradig beurteilt. Vorherrschend waren Mischkulturen aus zwei bis vier verschiedenen Keimarten. Monokulturen wurden aus 38% der Tupferproben isoliert. Am häufigsten gelang der Nachweis von E. coli variatio haemolytica (E. coli var. haem.) (58%) und Staphylococcus epidermidis (42%). Als weitere Spezies wurden E. coli, α-, β-hämolysierende Streptokokken, anhämolysierende Streptokokken, aerobe Bazillen, Staphylococcus aureus, Staphylococcus intermedius, Pasteurella multocida sowie Klebsiellen isoliert. Auffällig ist die hohe Nachweisrate von E. coli var. haem. mit 35% in Mischkulturen und 23% in Reinkultur. Schlussfolgerungen: Die physiologische Mikroflora der felinen Vaginalschleimhaut differiert deutlich von der der anöstrischen Hündin. Besonders die Dominanz von E. coli var. haem. in 38% der Mischkulturen und 23% der Monokulturen bei der Katze ist hervorzuheben. Klinische Relevanz: Die vorliegenden Ergebnisse geben eine erste Grundlage für die Interpretation mikrobiologischer Befunde feliner Vaginaltupfer.

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