COVID-19 Vaccination and the Daily Cases, Hospitalizations and Death Rates: a Case Study of Tennessee in the United States. (Preprint)
BACKGROUND The COVID-19 outbreak highlights the vulnerability to novel infections, and vaccination remains a foreseeable method to return to normal life. However, infrastructure is inadequate for the vaccination of the whole population immediately. Therefore, policies have adopted a strategy to vaccinate the elderly and vulnerable populations while delaying others. OBJECTIVE This study uses the Tennessee official statistic to understand how age-specific vaccination strategies reduce daily cases, hospitalization, and death rate. METHODS The research used publicly available data of COVID-19, including vaccination rates, positive cases, hospitalizations, and death from the health department of Tennessee. This study targeted from the first date of vaccinations, December 17, 2020, to March 3, 2021. The rates were adjusted by data from U.S. Census Bureau (2019), and the age groups were stratified at ten-year intervals from the age of 21. RESULTS The result shows that vaccination strategy can reduce the numbers of patients with COVID-19 in all age groups with lower hospitalization and death rates in older. The elderly had a 95% lower death rate from December to March, while no change in the death rate in other age groups. The hospitalization rate was reduced by 80% for people aged 80 or older, while people who were between 50 to 70 had almost the same hospitalization rate. CONCLUSIONS The study indicates that targeting older age groups for vaccination is the optimal way to avoid higher transmissions, reduce hospitalization and death rates. CLINICALTRIAL