scholarly journals Incidence of SARs-CoV-2 (Dikos-Ntsaaigii-19) Among Navajo Nation Children

2021 ◽  
Author(s):  
Joseph Angel De Soto ◽  
Babatunde Ojo
Keyword(s):  
Infection Rate ◽  
Death Rate ◽  
Signal Transduction Pathway ◽  
The United States ◽  
Vaccination Rate ◽  
Transduction Pathway ◽  
Bureau Of Indian Affairs ◽  
Infection Rates ◽  
Navajo Nation ◽  
Death Rates

On March 17, 2020 the SARs-CoV-2 virus was first reported on the Navajo Reservation. Today, the Navajo Nation has a 147% higher infection rate and a 450% higher death rate than the national average. Despite this tragedy, a glaring question remains, what is happening among the Navajo children. The study found that Navajo children had an infection rate 220% higher than the general population and a death rate from COVID 1,400% greater than non-Navajo in the United States. This occurs even though of Navajo children having a much higher vaccination rate of 68% compared to about 25% of children Nationwide. The introduction of SARs-CoV variants such as the alpha and omicron variants did not seem to play a role in these findings. The higher infection rates suggest a genetic predisposition among the Navajo to SARs-CoV-2 via the ACE-2 receptor and signal transduction pathway while the increased death rates may also suggest inferior care provided by the Bureau of Indian Affairs Hospitals.

scholarly journals The Effect of Vaccination Rates on the Infection of COVID-19 under the Vaccination Rate below the Herd Immunity Threshold

2021 ◽  
Vol 18 (14) ◽  
pp. 7491
Author(s):  
Yi-Tui Chen
Keyword(s):  
Infection Rate ◽  
Herd Immunity ◽  
The United States ◽  
Vaccination Rate ◽  
Infection Rates ◽  
Vaccination Rates ◽  
The United Kingdom ◽  
The World ◽  
Almost All ◽  
The Impact

Although vaccination is carried out worldwide, the vaccination rate varies greatly. As of 24 May 2021, in some countries, the proportion of the population fully vaccinated against COVID-19 has exceeded 50%, but in many countries, this proportion is still very low, less than 1%. This article aims to explore the impact of vaccination on the spread of the COVID-19 pandemic. As the herd immunity of almost all countries in the world has not been reached, several countries were selected as sample cases by employing the following criteria: more than 60 vaccine doses per 100 people and a population of more than one million people. In the end, a total of eight countries/regions were selected, including Israel, the UAE, Chile, the United Kingdom, the United States, Hungary, and Qatar. The results find that vaccination has a major impact on reducing infection rates in all countries. However, the infection rate after vaccination showed two trends. One is an inverted U-shaped trend, and the other is an L-shaped trend. For those countries with an inverted U-shaped trend, the infection rate begins to decline when the vaccination rate reaches 1.46–50.91 doses per 100 people.

scholarly journals 694 Insufficient sleep linked with higher COVID-19 infection cases and deaths in the United States

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A271-A271
Author(s):  
Azizi Seixas ◽  
Nicholas Pantaleo ◽  
Samrachana Adhikari ◽  
Michael Grandner ◽  
Giardin Jean-Louis
Keyword(s):  
Regression Models ◽  
Negative Binomial ◽  
The United States ◽  
Poor Sleep ◽  
County Level ◽  
Infection Rates ◽  
Insufficient Sleep ◽  
Death Rates ◽  
Rural Counties ◽  
The Relationship

Abstract Introduction Causes of COVID-19 burden in urban, suburban, and rural counties are unclear, as early studies provide mixed results implicating high prevalence of pre-existing health risks and chronic diseases. However, poor sleep health that has been linked to infection-based pandemics may provide additional insight for place-based burden. To address this gap, we investigated the relationship between habitual insufficient sleep (sleep <7 hrs./24 hr. period) and COVID-19 cases and deaths across urban, suburban, and rural counties in the US. Methods County-level variables were obtained from the 2014–2018 American community survey five-year estimates and the Center for Disease Control and Prevention. These included percent with insufficient sleep, percent uninsured, percent obese, and social vulnerability index. County level COVID-19 infection and death data through September 12, 2020 were obtained from USA Facts. Cumulative COVID-19 infections and deaths for urban (n=68), suburban (n=740), and rural (n=2331) counties were modeled using separate negative binomial mixed effects regression models with logarithmic link and random state-level intercepts. Zero-inflated models were considered for deaths among suburban and rural counties to account for excess zeros. Results Multivariate regression models indicated positive associations between cumulative COVID-19 infection rates and insufficient sleep in urban, suburban and rural counties. The incidence rate ratio (IRR) for urban counties was 1.03 (95% CI: 1.01 – 1.05), 1.04 (95% CI: 1.02 – 1.05) for suburban, and 1.02 (95% CI: 1.00 – 1.03) rural counties.. Similar positive associations were observed with county-level COVID-19 death rates, IRR = 1.11 (95% CI: 1.07 – 1.16) for urban counties, IRR = 1.04 (95% CI: 1.01 – 1.06) for suburban counties, and IRR = 1.03 (95% CI: 1.01 – 1.05) for rural counties. Level of urbanicity moderated the association between insufficient sleep and COVID deaths, but not for the association between insufficient sleep and COVID infection rates. Conclusion Insufficient sleep was associated with COVID-19 infection cases and mortality rates in urban, suburban and rural counties. Level of urbanicity only moderated the relationship between insufficient sleep and COVID death rates. Future studies should investigate individual-level analysis to understand the role of sleep mitigating COVID-19 infection and death rates. Support (if any) NIH (K07AG052685, R01MD007716, R01HL142066, K01HL135452, R01HL152453

Population-level analysis of antibiotic use and death rates in beef feedlots over ten years in three cattle-feeding regions of the United States

2021 ◽  
pp. 1-7
Author(s):  
Stephanie C. Rutten-Ramos ◽  
Shabbir Simjee ◽  
Michelle S. Calvo-Lorenzo ◽  
Jason L. Bargen
Keyword(s):  
Death Rate ◽  
Live Weight ◽  
Population Level ◽  
Antibiotic Use ◽  
The United States ◽  
Death Rates ◽  
Cattle Feeding ◽  
The Us ◽  
Rate Ratios ◽  
Beef Feedlots

Abstract OBJECTIVE To assess antibiotic use and other factors associated with death rates in beef feedlots in 3 regions of the US over a 10-year period. SAMPLE Data for 186,297 lots (groups) of finished cattle marketed between 2010 and 2019 were obtained from a database representing feedlots in the central, high, and north plains of the US. PROCEDURES Descriptive statistics were generated. Generalized linear mixed models were used to estimate lot death rates for each region, sex (steer or heifer), and cattle origin (Mexico or the US) combination. Death rate was calculated as the (number of deaths/number of cattle placed in the lot) × 100. Lot antibiotic use (TotalActiveMG/KGOut) was calculated as the total milligrams of active antibiotics assigned to the lot per live weight (in kilograms) of cattle marketed from the lot. Rate ratios were calculated to evaluate the respective associations between lot death rate and characteristics of cattle and antibiotic use. RESULTS Mean death rate increased during the 10-year period, peaking in 2018. Mean number of days on feed also increased over time. Mean TotalActiveMG/KGOut was greatest in 2014 and 2015, lowest in 2017, and moderated in 2018 and 2019. Death rate was positively associated with the number of days on feed and had a nonlinear association with TotalActiveMG/KGOut. Feeding medicated feed articles mitigated death rate. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested a balance between disease prevention and control in feedlots for cattle with various risk profiles. Additional data sources are needed to assess TotalActiveMG/KGOut across the cattle lifetime.

Calculating Age-Standardized Death Rates Among People With HIV Comparable Across Jurisdictions and Over Time

2021 ◽  
Vol 111 (1) ◽  
pp. 121-126
Author(s):  
Qiang Xia ◽  
Ying Sun ◽  
Chitra Ramaswamy ◽  
Lucia V. Torian ◽  
Wenhui Li
Keyword(s):  
United States ◽  
New York ◽  
New York City ◽  
York City ◽  
Death Rate ◽  
Age Distribution ◽  
The United States ◽  
Local Health ◽  
Death Rates ◽  
Over Time

The Centers for Disease Control and Prevention (CDC) and local health jurisdictions have been using HIV surveillance data to monitor mortality among people with HIV in the United States with age-standardized death rates, but the principles of age standardization have not been consistently followed, making age standardization lose its purpose—comparison over time, across jurisdictions, or by other characteristics. We review the current practices of age standardization in calculating death rates among people with HIV in the United States, discuss the principles of age standardization including those specific to the HIV population whose age distribution differs markedly from that of the US 2000 standard population, make recommendations, and report age-standardized death rates among people with HIV in New York City. When we restricted the analysis population to adults aged between 18 and 84 years in New York City, the age-standardized death rate among people with HIV decreased from 20.8 per 1000 (95% confidence interval [CI] = 19.2, 22.3) in 2013 to 17.1 per 1000 (95% CI = 15.8, 18.3) in 2017, and the age-standardized death rate among people without HIV decreased from 5.8 per 1000 in 2013 to 5.5 per 1000 in 2017.

Comparing the COVID-19 Responses in Cuba and the United States

2021 ◽  
Vol 111 (12) ◽  
pp. 2186-2193
Author(s):  
Mary Anne Powell ◽  
Paul C. Erwin ◽  
Pedro Mas Bermejo
Keyword(s):  
United States ◽  
Death Rate ◽  
Health Inequities ◽  
The United States ◽  
Death Rates ◽  
Excess Death ◽  
Future Studies ◽  
Effective Strategies ◽  
The Us ◽  
Case Rate

The purpose of this analytic essay is to contrast the COVID-19 responses in Cuba and the United States, and to understand the differences in outcomes between the 2 nations. With fundamental differences in health systems structure and organization, as well as in political philosophy and culture, it is not surprising that there are major differences in outcomes. The more coordinated, comprehensive response to COVID-19 in Cuba has resulted in significantly better outcomes compared with the United States. Through July 15, 2021, the US cumulative case rate is more than 4 times higher than Cuba’s, while the death rate and excess death rate are both approximately 12 times higher in the United States. In addition to the large differences in cumulative case and death rates between United States and Cuba, the COVID-19 pandemic has unmasked serious underlying health inequities in the United States. The vaccine rollout presents its own set of challenges for both countries, and future studies can examine the comparative successes to identify effective strategies for distribution and administration. (Am J Public Health. 2021;111(12):2186–2193. https://doi.org/10.2105/AJPH.2021.306526 )

Decline in Mortality Among Young Americans During the 20th Century: Prospects for Reaching National Mortality Reduction Goals for 1990

PEDIATRICS ◽  
1988 ◽  
Vol 82 (4) ◽  
pp. 582-595
Author(s):  
Robert A. Hoekelman ◽  
I. Barry Pless
Keyword(s):  
Health Care ◽  
Death Rate ◽  
Access To Health Care ◽  
Medical Science ◽  
The United States ◽  
Renal Diseases ◽  
Mortality Data ◽  
Mortality Reduction ◽  
Death Rates ◽  
National Mortality

A review of mortality data for persons younger than 25 years of age in the United States reveals striking declines in death rates since the turn of the century. Mortality among infants during their first year of life decreased from 1 in 6 in 1900 to 1 in 100 in 1986. Between 1900 and 1984 the annual death rate for children 1 through 4 years of age decreased from 1 in 50 to 1 in 2,000, for children 5 through 14 years of age, from 1 in 250 to 1 in 4,000, and for persons 15 through 24 years of age, from 1 in 165 to 1 in 1,000. Public health measures, advances in medical science, legislative initiatives, and the organization and delivery of health care have all contributed to these improvements in varying degrees during different decades. For the decade 1975 through 1984, the overall death rate decreased by 20%, with declines for all causes except suicide, cardiovascular diseases, and renal diseases. All of the surgeon general's mortality reduction goals for 1990 for America's youth should be reached except those for infant mortality and suicide. Improvement in these death rates will require better access to health care by those in need and reductions in environmental stress.

scholarly journals Primary and Probable Secondary Dengue Virus (DV) Infection Rates in Relation to Age among DV IgM-Positive Patients Residing in the United States Mainland Versus the Caribbean Islands

2011 ◽  
Vol 19 (1) ◽  
pp. 105-108 ◽  
Author(s):  
Harry E. Prince ◽  
Cindy Yeh ◽  
Mary Lapé-Nixon
Keyword(s):  
United States ◽  
Dengue Virus ◽  
Infection Rate ◽  
Primary Infection ◽  
Secondary Infection ◽  
The United States ◽  
Infection Rates ◽  
Caribbean Island ◽  
Caribbean Islands ◽  
The Caribbean

ABSTRACTDengue virus (DV) primary infection and probable secondary infection rates in relation to patient age (years) were determined for DV IgM-positive U.S. mainland residents (presumed travelers to areas of DV endemicity) and Caribbean island (area of DV endemicity) residents by evaluating IgG status and IgG avidity. Regardless of place of residence, most patients ≤20 years old exhibited primary infection and most patients >60 years old exhibited probable secondary infection. Among patients 21 to 60 years old, the primary infection rate was markedly higher in U.S. residents.

Confirmation of Tabachnick and Klugman's Hypothesis That the Death Instinct is Constant

1992 ◽  
Vol 74 (3_suppl) ◽  
pp. 1065-1066
Author(s):  
Patrick R. Saucer
Keyword(s):  
United States ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Death Rate ◽  
The United States ◽  
Chronic Liver ◽  
Death Instinct ◽  
Death Rates ◽  
Per Capita

In reporting the accident death rate and the chronic liver disease death rate for 1980, the Bureau of the Census divided the United States into nine areas. To test Tabachnick and Klugman's hypothesis that the amount of death instinct per capita remains constant across regions, the 1980 death rates for accidents and chronic liver disease were correlated. Contrary to earlier studies, the present study gave support for Tabachnick and Klugman's hypothesis.

scholarly journals Impact of altitude on COVID-19 infection and death in the United States: A modeling and observational study

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245055
Author(s):  
Kenton E. Stephens ◽  
Pavel Chernyavskiy ◽  
Danielle R. Bruns
Keyword(s):  
Regression Analysis ◽  
Population Density ◽  
The United States ◽  
Infection Rates ◽  
Treatment Interventions ◽  
Death Rates ◽  
Ongoing Work ◽  
Per Capita ◽  
Case Mortality ◽  
Relevant Covariates

Background COVID-19, the disease caused by SARS-CoV-2, has caused a pandemic, sparing few regions. However, limited reports suggest differing infection and death rates across geographic areas including populations that reside at higher elevations (HE). We aimed to determine if COVID-19 infection, death, and case mortality rates differed in higher versus low elevation (LE) U.S. counties. Methods Using publicly available geographic and COVID-19 data, we calculated per capita infection and death rates and case mortality in population density matched HE and LE U.S. counties. We also performed population-scale regression analysis to investigate the association between county elevation and COVID-19 infection rates. Findings Population density matching of LA (< 914m, n = 58) and HE (>2133m, n = 58) counties yielded significantly lower COVID-19 cases at HE versus LE (615 versus 905, p = 0.034). HE per capita deaths were significantly lower than LE (9.4 versus 19.5, p = 0.017). However, case mortality did not differ between HE and LE (1.78% versus 1.46%, p = 0.27). Regression analysis, adjusted for relevant covariates, demonstrated decreased COVID-19 infection rates by 12.82%, 12.01%, and 11.72% per 495m of county centroid elevation, for cases recorded over the previous 30, 90, and 120 days, respectively. Conclusions This population-adjusted, controlled analysis suggests that higher elevation attenuates infection and death. Ongoing work from our group aims to identify the environmental, biological, and social factors of residence at HE that impact infection, transmission, and pathogenesis of COVID-19 in an effort to harness these mechanisms for future public health and/or treatment interventions.

scholarly journals COVID-19 Vaccination and the Daily Cases, Hospitalizations and Death Rates: a Case Study of Tennessee in the United States. (Preprint)

2021 ◽  
Author(s):  
Ali Roghani
Keyword(s):  
Death Rate ◽  
Age Groups ◽  
Vaccination Strategy ◽  
The Elderly ◽  
Health Department ◽  
The United States ◽  
Census Bureau ◽  
Hospitalization Rate ◽  
Death Rates ◽  
Vaccination Rates

BACKGROUND The COVID-19 outbreak highlights the vulnerability to novel infections, and vaccination remains a foreseeable method to return to normal life. However, infrastructure is inadequate for the vaccination of the whole population immediately. Therefore, policies have adopted a strategy to vaccinate the elderly and vulnerable populations while delaying others. OBJECTIVE This study uses the Tennessee official statistic to understand how age-specific vaccination strategies reduce daily cases, hospitalization, and death rate. METHODS The research used publicly available data of COVID-19, including vaccination rates, positive cases, hospitalizations, and death from the health department of Tennessee. This study targeted from the first date of vaccinations, December 17, 2020, to March 3, 2021. The rates were adjusted by data from U.S. Census Bureau (2019), and the age groups were stratified at ten-year intervals from the age of 21. RESULTS The result shows that vaccination strategy can reduce the numbers of patients with COVID-19 in all age groups with lower hospitalization and death rates in older. The elderly had a 95% lower death rate from December to March, while no change in the death rate in other age groups. The hospitalization rate was reduced by 80% for people aged 80 or older, while people who were between 50 to 70 had almost the same hospitalization rate. CONCLUSIONS The study indicates that targeting older age groups for vaccination is the optimal way to avoid higher transmissions, reduce hospitalization and death rates. CLINICALTRIAL

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