STUDY OF ACCESSORY SUPRAORBITAL FORAMEN IN NORTH INDIAN HUMAN SKULL

Objective: This research was aimed at telling the anatomical characteristics of the accessory supraorbital foramen (ASOF) in relation to the main supraorbital foramen (SOF), which is necessary in clinical situations that require regional surgical procedures. Methods: A total dedicated to the presence and location of 72 dry Indian adults of unknown age and sex were investigated. In each skull, the ASOF location was measured on both sides with a Vernier caliper metal case, with the SOF as the reference point. The total number of accessory foramen was also noted. Results: Accessory infraorbital foramens (IOFs) were seen only in 4.16% in our study and all seen were single in number. Half of those accessory foramen were present on medial and rest half were present on superomedial position as compared to the main IOF. Half among present accessory foramens were located at a distance of <2 mm and half were located at a distance of more than 2 mm. The mean location of accessory IOF was at 7.07 mm from main IOF. Conclusion: Knowledge of the anatomical characteristics of ASOF can have major effects on surgical and local anesthetic preparation blockage of the super orbital nerves. Additional guidance for surgeons may be provided with information on the foramens obtained from this study. The surgeons should note this during the nerve block as damage to either branch will lead to sensory impairment and incomplete blocking of the nerve.

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Sella turcica bridging and ossified carotico-clinoid ligament: Correlation with sex and age

The Neuroradiology Journal ◽

10.1177/1971400917751036 ◽

2018 ◽

Vol 31 (3) ◽

pp. 299-304 ◽

Cited By ~ 4

Author(s):

Daniele Gibelli ◽

Michaela Cellina ◽

Stefano Gibelli ◽

Marta Panzeri ◽

Antonio Giancarlo Oliva ◽

...

Keyword(s):

Computed Tomography ◽

Logistic Regression ◽

Regression Analysis ◽

Surgical Procedures ◽

Age Groups ◽

Sella Turcica ◽

Anterior Clinoid Process ◽

Computed Tomography Scans ◽

The Mean ◽

Age And Sex

Aim Sella turcica bridging and ossified carotico-clinoid ligament are two variants of the sella turcica, the origin of which is partially unknown. These variations should be properly recognised, as they may hamper the removal of the anterior clinoid process in surgical procedures. Therefore, our aim was to determine the prevalence of these two anatomical variants and to investigate their prevalence according to patient sex and age in a series of maxilla computed tomography scans. Materials and methods We revised 300 computed tomography scans of the head from northern Italian patients, stratified into three age groups (18–40 years, 41–60 years, >60 years): a logistic regression analysis was used to explore an association of sella turcica bridging with age and sex through Matlab software, also including a test for the extracted model ( P < 0.05). Results The mean prevalence of sella turcica bridging and ossified carotico-clinoid ligament were 0.16 ± 0.06 (48/300, 16.0%) and 0.09 ± 0.03 (26/300, 8.7%), respectively. Statistically significant differences according to sex were found neither for sella turcica bridging ( P = 0.345) nor for ossified carotico-clinoid ligament ( P = 0.412). Only sella turcica bridging showed a correlation with age ( P = 0.007). In addition, the two variants were often associated, as patients without sella turcica bridging usually did not show ossified carotico-clinoid ligament ( P < 0.001). Discussion Our results suggest an association between the two variants, and provide a novel contribution to the debate around their origin.

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Extended Myectomy for Hypertrophic Obstructive Cardiomyopathy

The Heart Surgery Forum ◽

10.1532/hsf98.20111185 ◽

2012 ◽

Vol 15 (5) ◽

pp. 251

Author(s):

Changqing Gao ◽

Chonglei Ren ◽

Cangsong Xiao ◽

Yang Wu ◽

Gang Wang ◽

...

Keyword(s):

Mitral Valve ◽

Left Ventricle ◽

Mitral Regurgitation ◽

Surgical Procedures ◽

Hypertrophic Obstructive Cardiomyopathy ◽

Systolic Anterior Motion ◽

Anterior Leaflet ◽

Septal Myectomy ◽

The Mean

Background: The purpose of this study was to summarize our experience of extended ventricular septal myectomy in patients with hypertrophic obstructive cardiomyopathy (HOCM).Methods: Thirty-eight patients (26 men, 12 women) with HOCM underwent extended ventricular septal myectomy. The mean age was 36.3 years (range, 18-64 years). Diagnosis was made by echocardiography. The mean (mean � SE) systolic gradient between the left ventricle (LV) and the aorta was 89.3 � 31.1 mm Hg (range, 50-184 mm Hg) according to echocardiographic assessments before the operations. Moderate or severe systolic anterior motion (SAM) of the anterior leaflet of the mitral valve was found in 38 cases, and mitral regurgitation was present in 29 cases. Extended ventricular septal myectomy was performed in all 38 cases. The results of the surgical procedures were evaluated intraoperatively with transesophageal echocardiography (TEE) and with transthoracic echocardiography (TTE) at 1 to 2 weeks after the operation. All patients were followed up with TTE after their operation.Results: All patients were discharged without complications. The TEE evaluations showed that the mean systolic gradient between the LV and the aorta decreased from 94.8 � 35.6 mm Hg preoperatively to 13.6 � 10.8 mm Hg postoperatively (P = .0000) and that the mean thickness of the ventricular septum decreased from 28.3 � 7.9 mm to 11.8 � 3.2 mm (P = .0000). Mitral regurgitation and SAM were significantly reduced or eliminated. During the follow-up, all patients promptly became completely asymptomatic or complained of mild effort dyspnea only, and syncope was abolished. TTE examinations showed that the postoperative pressure gradient either remained the same or diminished.Conclusions: Extended ventricular septal myectomy is mostly an effective method for patients with HOCM, and good surgical exposure and thorough excision of the hypertrophic septum are of paramount importance for a successful surgery.

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Comparative Analysis of Different Local Anesthetic Solutions Available in Market: An In Vitro and Clinical Study

European Journal of Dentistry ◽

10.1055/s-0041-1727553 ◽

2021 ◽

Author(s):

Eisha Imran ◽

Faisal Moeen ◽

Beenish Abbas ◽

Bakhtawar Yaqoob ◽

Mehreen Wajahat ◽

...

Keyword(s):

Comparative Analysis ◽

Local Anesthetic ◽

Compositional Analysis ◽

Bacterial Activity ◽

Similar Composition ◽

Ph Values ◽

Significant Difference ◽

The Mean ◽

The Difference

Abstract Objectives The study aimed to evaluate and compare various commercially available local anesthetic solutions. Materials and Methods A total of 150 commercially available local anesthetic cartridges of similar composition (2% lidocaine with epinephrine 1:100,000) were randomly collected and divided into 3 groups. The designations of groups were selected from their product names such that each group consisted of 60 cartridges. Group S (Septodont, France) Group M (Medicaine, Korea) and Group H (HD-Caine, Pakistan). The samples were divided into five sub-groups, each consisting of 10 cartridges from each group to investigate each parameter. Results The acquired data was statistically analyzed and compared (using SPSS version 12). Compositional analysis revealed a non-significant (P>0.05) difference when the three Groups were compared with standard lidocaine and epinephrine solutions. The mean pH values of samples from group S, M and H respectively fell within the range of pH values of commercially available solutions. Non-significant difference in EPT values of Group S and H was found when efficacy was compared (p = 0.3), however a significant difference (p < 0.01) was observed in contrast to Group M. Anti-bacterial activity was observed in all the group and a non-significant difference in cell viability values of Group S and M was found (p = 0.6), while the difference was significant in comparison to Group H. Conclusion Within the limitations of these investigations, it appears that the properties of different manufacturers fall within the recommended ranges as mentioned in literature and do not appear to be statistically different in the variables we have tested.

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Comparison of corneal astigmatism characteristics and prevalence of corneal astigmatism between Turkish individuals and Syrian refugees

European Journal of Ophthalmology ◽

10.1177/11206721211030779 ◽

2021 ◽

pp. 112067212110307

Author(s):

Soner Guven

Keyword(s):

Quantitative Analysis ◽

Cataract Surgery ◽

Corneal Astigmatism ◽

Syrian Refugees ◽

Vector Method ◽

Adjusted Analysis ◽

Younger Age ◽

The Mean ◽

Age And Sex

Purpose: To compare the prevalence, magnitude and type of corneal astigmatism between Turkish individuals and Syrian refugees. Material and methods: Data of patients scheduled for cataract surgery between January 2019 and 2020 were reviewed. The patients were randomly stratified according to their ethnicity (Turkish individuals or Syrian refugees). Keratometry was performed with the keratometer of IOLMaster 500. Quantitative analysis was performed using the power vector method (J0 and J45). The association between age and astigmatism in the two groups was explored. Results: The study included 4085 eyes of 2049 patients (3962 eyes of Turkish individuals and 123 eyes of Syrian refugees). The mean magnitude of corneal astigmatism, J0, J45 and prevalence of against the rule (ATR) astigmatism and with the rule (WTR) astigmatism were 1.01 D, 0.06, 0.01 D, 37.6% and 43.7% in Turkish individuals and 1.13 D, −0.02, 0.07 D, 46.3% and 37.4% in Syrian refugees, respectively. There were no significant differences according to age, sex, right/left eyes, corneal astigmatism magnitude, keratometric values, J0 and J45 ( p > 0.05) between the two groups. Below 40 years of age, the mean corneal astigmatism magnitude in Syrian refugees was significantly higher than that in Turkish individuals ( p = 0.037). At all ages, ATR astigmatism prevalence was higher in Syrian refugees than in Turkish individuals. ATR astigmatic shift began at a younger age in Syrian refugees ( p = 0.037). Age- and sex-adjusted analysis showed that J0 was significantly lower in Syrian refugees than in Turkish individuals ( p = 0.013). Conclusion: The prevalence and magnitude of ATR astigmatism were higher and onset earlier in Syrian refugees than in Turkish individuals.

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Enlargement of cerebrospinal fluid spaces in long-term benzodiazepine abusers

Psychological Medicine ◽

10.1017/s0033291700000660 ◽

1987 ◽

Vol 17 (4) ◽

pp. 869-873 ◽

Cited By ~ 37

Author(s):

C. Schmauss ◽

J.-C. Krieg

Keyword(s):

Low Dose ◽

Matched Control ◽

Control Group ◽

High Dose ◽

Withdrawal Therapy ◽

The Mean ◽

Dose Dependent ◽

Dose Dependent Effect ◽

Age And Sex

SynopsisIn 17 benzodiazepine (BDZ) dependent in-patients a CT scan was performed before initiation of withdrawal therapy. The evaluation of the ventricular to brain ratio (VBR) by standardized and computerized measurements revealed significantly higher mean VBRs for both high-and low-dose BDZ-dependent patients compared to the mean VBR of an age- and sex-matched control group. In addition, the mean VBR of high-dose BDZ-dependent patients (N = 8) was significantly higher than the mean VBR of low-dose BDZ-dependent patients (N = 9). This difference could not be accounted for by the age of the patients or duration of BDZ-dependency and, therefore, suggests a dose-dependent effect of BDZs on the enlargement of internal CSF-spaces. On the other hand, higher values for the width of external CSF-spaces were found to be related to increasing age of the patients and duration of BDZ-dependency.

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Cross-sectoral Analysis of 1.4 Million AOK-insured Patients with Back Pain in Baden-Württemberg – What Influence does Outpatient Specialist Care Have?

Zeitschrift für Orthopädie und Unfallchirurgie ◽

10.1055/a-1542-9327 ◽

2021 ◽

Author(s):

Tom R. Jansen ◽

Heinz Endres ◽

Lina Barnewold ◽

Petra Kaufmann-Kolle ◽

Sabine Knapstein ◽

...

Keyword(s):

Primary Care ◽

Back Pain ◽

Surgical Procedures ◽

Regional Differences ◽

Pain Medication ◽

Hospital Treatment ◽

Specialist Care ◽

Billing Data ◽

Primary Care Clinics ◽

The Mean

Abstract Background Back pain is one of the leading causes of disability globally and the most common musculoskeletal pain in Germany. The lifetime prevalence of back pain ranges from 74% to 85%, and the point prevalence ranges from 32% to 49%. One in five individuals with statutory health insurance visits a doctor at least once a year for back pain, and 1 in 20 individuals is on sick leave at least once a year. The question as to what extent can different outpatient care concepts substantially contribute to improving care and avoiding inpatient hospital treatment has repeatedly been the subject of controversial political discussions. This study aimed to present a description of the reality of care in Baden-Württemberg (BW), Germany, based on claims data. Material and Methods Anonymised routine billing data of AOK Baden-Württemberg were analysed in compliance with data protection regulations. The billing data cover the outpatient and inpatient care sectors. All AOK patients in BW who received at least one ICD10 diagnosis from their physician in the first half of 2015 were considered for the analysis. Patients with at least one diagnosis of back pain were evaluated as patients with back pain, whereby the assignment to the diagnosis group of specific or non-specific back pain was made based on the code. Results In the first half of 2015, nearly 988 925 patients with back pain were registered in the 6696 primary care clinics in BW, approximately 302 524 patients in 1172 orthopaedic clinics and 17 043 patients in 89 neurosurgical clinics. Primary care clinics reported back pain diagnosis in 34.6%, orthopaedic clinics in 51.9% and neurosurgical clinics in 78.6% of cases. Primary care clinics diagnosed a specific cause in approximately one-third of patients with back pain, orthopaedic clinics in approximately 40% of their patients and neurosurgery clinics in one in two cases. Overall, approximately 1.2% of 1.3 million patients with back pain (January to December 2015 in BW) were hospitalised. Inpatient therapy consisted of surgical therapy and conservative therapy. Nucleotomy, decompression and spondylodesis were the three most common surgical procedures performed. Pain medication and remedy prescriptions decreased pain after spinal surgery. There are significant regional differences in referral and surgery rates. The mean inpatient referral rate was 535 of 100 000 AOK insurants, and the median was 536 of 100 000 AOK insurants. The mean surgery rate among all admitted patients with back pain was 49.9%, and the median was 49.8%. Conclusion The vast majority of patients with back pain are treated as outpatients. Only approximately 1.2% of all patients with back pain were treated as inpatients in 2015. Of these, approximately half underwent surgery. Spinal surgeries led to a decrease in pain medication and remedy prescription postoperatively. The three most frequent surgical procedures were ‘decompression’, ‘excision of disc tissue’ and ‘spondylodesis’. There were significant regional differences.

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HEAD CIRCUMFERENCE, MENTAL RETARDATION, AND GROWTH FAILURE

PEDIATRICS ◽

10.1542/peds.36.1.62 ◽

1965 ◽

Vol 36 (1) ◽

pp. 62-66

Author(s):

Edward J. O'Connell ◽

Robert H. Feldt ◽

Gunnar B. Stickler

Keyword(s):

Mental Retardation ◽

Head Circumference ◽

Growth Failure ◽

Clinical Impression ◽

Severe Mental Retardation ◽

Small Head ◽

The Mean ◽

Standard Deviations ◽

Mental Subnormality ◽

Age And Sex

The purpose of this study was to re-affirm our clinical impression that non-institutionalized children whose head circumference was below minus 2 standard deviations were mentally subnormal and frequently had growth failure. A group of 134 children with a head circumference below minus 2 standard deviations from the mean were studied, and all but one were mentally subnormal. The most severe mental retardation was noted in the group of children with a head circumference of minus 4 standard deviations or below. We found, as have others, that children with mental retardation have height and weights below the expected norm and that children with a head circumference below minus 2 standard deviations have even lower mean heights and weights. The head circumference of 31 children with growth failure and normal intelligence was normal for age and sex, therefore disproving the concept that the abnormally small child has a proportionally small head. In the child with growth failure, should the head be proportionally small (below minus 2 standard deviations), mental subnormality should be suspected. We feel that the head circumference measurement has taken on new clinical significance in that our data support its use in suspecting the association of mental subnormality in children with growth failure and a head circumference of below minus 2 standard deviations from the mean for age and sex.

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Estimation of Starch and Sugar Intake in a Japanese Population Based on a Newly Developed Food Composition Database

Nutrients ◽

10.3390/nu10101474 ◽

2018 ◽

Vol 10 (10) ◽

pp. 1474 ◽

Cited By ~ 21

Author(s):

Aya Fujiwara ◽

Kentaro Murakami ◽

Keiko Asakura ◽

Ken Uechi ◽

Minami Sugimoto ◽

...

Keyword(s):

Preschool Children ◽

Dairy Products ◽

Age Groups ◽

Food Composition ◽

Total Sugar ◽

Food Sources ◽

Sugar Intake ◽

Dietary Record ◽

The Mean ◽

Age And Sex

Due to a lack of a food composition database on starch and sugars, we developed a comprehensive database on starch and seven types of sugars in commonly consumed foods (n = 2222) in Japan. Dietary record data of 368 toddlers (aged 18–35 months), 376 preschool children (aged 3–6 years), 915 schoolchildren (aged 8–14 years) and 392 adults (aged 20–69 years) were used. The mean starch intake ranged from 55.6 g/day (female toddlers) to 206.0 g/day (male schoolchildren). Irrespective of age and sex, >50% of starch was provided by rice and grains. The mean total sugar intake ranged from 46.1 g/day (female toddlers) to 68.7 g/day (male schoolchildren). In all age and sex groups, the major contributors of total sugar included sucrose (mean: 18.2–34.0 g/day), glucose (7.8–13.1 g/day), lactose (5.3–13.1 g/day) and fructose (7.6–11.1 g/day). The top food sources were dairy products (toddlers) and confectionaries (other age groups) for total sugar, confectionaries for sucrose, fruits (toddlers) and vegetables (other age groups) for glucose, dairy products for lactose and fruits (toddlers and preschool children) and vegetables (schoolchildren and adults) for fructose. In conclusion, this study clarified the starch and sugar intake in Japan and provides a foundation for future research.

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Level I to III craniofacial approaches based on Barrow classification for treatment of skull base meningiomas: surgical technique, microsurgical anatomy, and case illustrations

Neurosurgical FOCUS ◽

10.3171/2011.3.focus1110 ◽

2011 ◽

Vol 30 (5) ◽

pp. E5 ◽

Cited By ~ 8

Author(s):

Emel Avcı ◽

Erinç Aktüre ◽

Hakan Seçkin ◽

Kutluay Uluç ◽

Andrew M. Bauer ◽

...

Keyword(s):

Surgical Technique ◽

Skull Base ◽

Surgical Anatomy ◽

Microsurgical Anatomy ◽

Middle Point ◽

The Mean ◽

The Right ◽

Skull Base Meningiomas ◽

Supraorbital Foramen ◽

Ethmoidal Foramen

Object Although craniofacial approaches to the midline skull base have been defined and surgical results have been published, clear descriptions of these complex approaches in a step-wise manner are lacking. The objective of this study is to demonstrate the surgical technique of craniofacial approaches based on Barrow classification (Levels I–III) and to study the microsurgical anatomy pertinent to these complex craniofacial approaches. Methods Ten adult cadaveric heads perfused with colored silicone and 24 dry human skulls were used to study the microsurgical anatomy and to demonstrate craniofacial approaches in a step-wise manner. In addition to cadaveric studies, case illustrations of anterior skull base meningiomas were presented to demonstrate the clinical application of the first 3 (Levels I–III) approaches. Results Cadaveric head dissection was performed in 10 heads using craniofacial approaches. Ethmoid and sphenoid sinuses, cribriform plate, orbit, planum sphenoidale, clivus, sellar, and parasellar regions were shown at Levels I, II, and III. In 24 human dry skulls (48 sides), a supraorbital notch (85.4%) was observed more frequently than the supraorbital foramen (14.6%). The mean distance between the supraorbital foramen notch to the midline was 21.9 mm on the right side and 21.8 mm on the left. By accepting the middle point of the nasofrontal suture as a landmark, the mean distances to the anterior ethmoidal foramen from the middle point of this suture were 32 mm on the right side and 34 mm on the left. The mean distance between the anterior and posterior ethmoidal foramina was 12.3 mm on both sides; the mean distance between the posterior ethmoidal foramen and distal opening of the optic canal was 7.1 mm on the right side and 7.3 mm on the left. Conclusions Barrow classification is a simple and stepwise system to better understand the surgical anatomy and refine the techniques in performing these complex craniofacial approaches. On the other hand, thorough anatomical knowledge of the midline skull base and variations of the neurovascular structures is crucial to perform successful craniofacial approaches.

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The Development of Fundamental Frequency in 6- to 10-Year Old Children: A Brief Study

Journal of the International Phonetic Association ◽

10.1017/s0025100300006241 ◽

1998 ◽

Vol 28 (1-2) ◽

pp. 55-62 ◽

Cited By ~ 1

Author(s):

S. P. Whiteside ◽

C. Hodgson

Keyword(s):

Standard Deviation ◽

Fundamental Frequency ◽

Picture Naming ◽

Age Groups ◽

Naming Task ◽

Final Position ◽

The Mean ◽

Age And Sex

This brief study investigates the development of fundamental frequency (FO) in pre-adolescent children as a function of age and sex. The children who took part in the study were divided into three age groups: 6, 8 and 10 years. Each group consisted of three males and three females. Each subject produced nine target phrases with [] in phrase-final position, which were elicited via a picture-naming task. FO was estimated for the nine target utterances and the following FO parameters were derived: mean FO for the whole phrase; FO range for the whole phrase; standard deviation values of FO for the whole phrase and mean FO for the phrase-final vowel [α:]. Results indicated that FO parameters generally decreased with age, and by age 10 years the males had lower values than the females for all four parameters. Results also indicated that the mean standard deviation of FO across the phrase was significantly higher for the females compared to that for the males.

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