scholarly journals PATCHES FOR ACNE TREATMENT: AN UPDATE ON THE FORMULATION AND STABILITY TEST

2021 ◽  
pp. 21-26
Author(s):  
TAQIYYAH QOTHRUNNADAA ◽  
ALIYA NUR HASANAH
Keyword(s):  
Relative Humidity ◽  
Secondary Infection ◽  
Acne Vulgaris ◽  
Stability Test ◽  
Google Scholar ◽  
Acne Treatment

The purpose of this article review was to find out more about acne patch formulations and test stability. The method used is searching data from various articles based on Google Scholar, Elsevier, and Molecules with the keywords "Acne vulgaris, acne treatment, acne patches, and types of acne patches” and with a range of years between 2011 and 2021. Based on the type of acne, acne patches are divided into several types, namely microneedle patches, acne medicine patches, and hydrocolloid patches. The results obtained in this review show that the most commonly used acne patch is the medicated acne patch (hydrogel patches), because of its waterproof property to protect acne from secondary infection, it can absorb liquid inside and flatten acne and is cheaper compared to microneedles. The hydrogel patch is also stable at a temperature of 40±2 °C and a relative humidity (RH) of 75±5% for 6 mo of storage.

Effects of topical acne treatment on the ocular surface in patients with acne vulgaris

2016 ◽  
Vol 39 (6) ◽  
pp. 431-434 ◽  
Author(s):  
Seray Aslan Bayhan ◽  
Hasan Ali Bayhan ◽  
Emine Çölgeçen ◽  
Canan Gürdal
Keyword(s):  
Ocular Surface ◽  
Acne Vulgaris ◽  
Acne Treatment

scholarly journals A Novel Biocompatible Herbal Extract-Loaded Hydrogel for Acne Treatment and Repair

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Ying-Yi Lin ◽  
Shu-Hsu Lu ◽  
Rong Gao ◽  
Chia-Hung Kuo ◽  
Wen-Hisn Chung ◽  
...  
Keyword(s):  
Raw Materials ◽  
Acne Vulgaris ◽  
Morphological Characteristics ◽  
Zingiber Officinale ◽  
Herbal Extract ◽  
Gravimetric Analysis ◽  
Matrix Properties ◽  
Acne Treatment ◽  
Anti Inflammatory ◽  
Clinical Trial Results

A novel herbal extract-loaded gel containing several biofunctional extracts, including green tea, Zingiber officinale Rosc, Phyllanthus emblica, and salicylic acid, was developed for acne vulgaris. These natural raw materials were blended with suitable dosages of gelatin and carboxymethyl cellulose (CMC) to produce a biocompatible herbal gel. The physical chemistry properties of the hydrogel were determined by Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), rheometry, and scanning electron microscopy (SEM), and the hydrogel showed good mechanical and morphological characteristics. The herbal extract-loaded hydrogel mimicked extracellular matrix properties and showed good antioxidant and anti-inflammatory properties and various advantages, serving as a potential wound dressing material because of its high moisture retention ability, wound exudate absorption behavior, and biocompatibility. It exhibited moderate-high antioxidative and anti-inflammatory qualities that were important for dermis wound closure. The clinical trial results showed that most patients experienced moderate to high healing rates, and four of twenty-four individuals (16.67%) had recovery area ratios greater than 80%. This herbal extract-loaded hydrogel has effective ingredients and excellent mechanical properties as a bioactive dressing agent for acne treatment.

scholarly journals Eficacia de la espironolactona en el tratamiento del acné vulgar. Una revisión sistemática

2021 ◽  
Vol 10 (19) ◽  
pp. 214-222
Author(s):  
Ana Laura Pichardo-Ávalos ◽  
Mario I Ortiz ◽  
Raquel Cariño-Cortés
Keyword(s):  
Mixed Methods ◽  
Acne Vulgaris ◽  
Google Scholar ◽  
Cochrane Library ◽  
Revisión Sistemática ◽  
Appraisal Tool

Objetivo: Analizar la eficacia de la terapia con espironolactona en el tratamiento del acné vulgar reportada desde 1980 hasta Marzo del 2021. Métodos: Se realizó una búsqueda en las siguientes bases de datos: Scopus, PubMed, Embase, Science direct, Cochrane Library y Google Scholar, se seleccionaron aquellos artículos que reportaron el seguimiento de pacientes con Acné Vulgaris tratados con espironolactona. Tres revisores evaluaron la calidad metodológica mediante la “Mixed Methods Appraisal Tool” (MMAT), versión 2018. Resultados: Se seleccionaron 15 artículos con tratamientos acompañantes, comparativos o ambos y cinco artículos con monoterapia de espironolactona que no se complementaban ni comparaban. Se reportó una eficacia variable en los 20 artículos que fueron seleccionados. Las cinco reacciones adversas con mayor frecuencia en los estudios analizados fueron: alteraciones menstruales, hiperkalemia, pigmentación localizada en el sitio del tratamiento, mareos y fatiga. Conclusiones: Considerar que aún con la diversidad de tipos de estudios, se reporta un gran porcentaje de disminución del acné, por lo tanto, las evidencias indican que el tratamiento podría ser eficaz bajo condiciones controladas.

PREPARATION AND EVALUATION OF BB CONCEALER CREAM CONTAINING NEEM OIL FOR ACNE TREATMENT

INDIAN DRUGS ◽  
2021 ◽  
Vol 58 (11) ◽  
pp. 66-69
Author(s):  
Priyal Jangla ◽  
Khushboo Merai ◽  
Drishti Patel ◽  
Kalyani Sheth ◽  
Keyword(s):  
Inflammatory Disease ◽  
Acne Vulgaris ◽  
In Vitro Release ◽  
Antibacterial Properties ◽  
Neem Oil ◽  
Release Studies ◽  
Acne Treatment ◽  
Preparation And Evaluation ◽  
Vitro Release

Acne vulgaris is a chronic dermatological inflammatory disease with symptoms like redness, comedones and blemishes appearing on face and neck. Propionobacterium acnes plays an important role in this disease. Neem oil, an ayurvedic, anti-bacterial medicine is non-comedogenic. Concealer is a type of cosmetic used to mask and camouflage blemishes and imperfections visible on skin and are available as liquid, balm, cream and stick. BB creams in cosmetics is termed as “beauty balm, blemish base, blemish balm” designed to serve as foundation, moisturizer and sunscreen all at once. The current study was to develop an aesthetic BB cream combining an anti-acne activity with concealing effect. Concentrations of upto 25 %w/w neem oil was prepared and evaluated for appearance, texture, pH, spreadability, antibacterial properties and in vitro release studies. All the formulations confirmed activity against P. acnes. Prolonged activity of neem oil observed at the end of 6 h as demonstrated in vitro

Developing an Effective Formulation for an Acne Treatment Cream with Ocimum Basilicum using Invasome

2018 ◽  
Author(s):  
Hyun Jee Han
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Antioxidant Activities ◽  
Acne Vulgaris ◽  
Ocimum Basilicum ◽  
Common Disease ◽  
Stability Performance ◽  
Acneiform Eruption ◽  
Acne Treatment

Cosmeceuticals formulations of Ocimum Basilicum are designed in an effective base for topical acne-causing inflammation medication using advanced drug delivery system. Acne vulgaris is a common disease found not only among the youth but also among adults. The present study suggests the use of Ocimum Basilicum as a cream for acne treatment. The anti-acne cream is formulated from herbal crude extracts for the antimicrobial and antioxidant activities of the formulation to prevent inflammation which causes acneiform eruption. The study proposes that, along with the formulation of micro-emulsion, the use of invasome will be an effective advanced drug delivery system which can promise a great efficacy and stability performance, while simultaneously ensuring the anti-acne effect by Ocimum Basilicum.  

Acne Treatment With Light Absorbing Gold Microparticles and Optical Pulses: An Open‐Label European Multi‐Centered Study in Moderate to Moderately Severe Acne Vulgaris Patients

2019 ◽  
Vol 51 (8) ◽  
pp. 686-693 ◽  
Author(s):  
Christine Sofie Krohn Fuchs ◽  
Christiane Bay ◽  
Maurice Adatto ◽  
Hans Lomholt ◽  
Merete Haedersdal
Keyword(s):  
Acne Vulgaris ◽  
Optical Pulses ◽  
Open Label ◽  
Severe Acne ◽  
Acne Treatment

scholarly journals Stability test for mastitis reagent ad us. vet.

2013 ◽  
Vol 29 (2) ◽  
pp. 399-404
Author(s):  
V. Vukovic ◽  
M. Vicentijevic ◽  
N. Plavsa
Keyword(s):  
Relative Humidity ◽  
Shelf Life ◽  
Ph Value ◽  
Storage Conditions ◽  
Stability Test ◽  
Initial State ◽  
The Stability

In the stability test of the mastitis reagent ad us.vet., as the finished product, three production series were tested in quantities of 500 ml of the sample, under appropriate storage conditions. For the testing, the appropriate uniformity of temperature and relative humidity was provided. Also, the procedure of the stability test was determined, which included the initial state, then every three months until the end of the first trial and a final testing at the end of shelf life (0, 3, 6, 9, 12 and 18 months). Of the tested parameters the following were included: appearance, pH value of the solution, dry residue (in %) and microbiological purity.

scholarly journals Proposal for a 4-type Classification of Acne: An Evidence-Based Review of the Literature

2020 ◽  
Vol 14 (1) ◽  
pp. 38-43
Author(s):  
O. Prapapan ◽  
C. C. Chatchavarn ◽  
P. Suvanprakorn ◽  
H. A. M. Neumann ◽  
R. Knobler ◽  
...  
Keyword(s):  
Acne Vulgaris ◽  
Risk Of Bias ◽  
Evidence Based ◽  
Review Of The Literature ◽  
Medical Practitioners ◽  
Acne Treatment ◽  
Evidence Based Guideline ◽  
Based Medicine ◽  
Type Classification

Background: Proper evidence-based classification and grading of a disease such as acne are important in guiding medical practitioners to properly diagnose diseases and treat patients. Objective: This is a review of the present classification of acne in order to delineate modified approaches of acne treatment. Methods: The available literature was reviewed, including searches from 7 databases based on the terms “classification of acne vulgaris and pathophysiology”, according to evidence-based medicine using the Cochrane risk of bias tool. Results: From a total of 10,121 studies on acne classification, 51 full-text articles were assessed and 13 studies were included after screening for acne classification. Conclusion: The European-evidence-based guideline (EDF) classification fits best. We propose a modified classification in 4 categories to improve the management of each stage of acne.

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