Liquid-phase exfoliation of black sesame to create a nanoplatform for in vitro photoluminescence and photothermal therapy

Nanomedicine ◽  
2020 ◽  
Vol 15 (21) ◽  
pp. 2041-2052
Author(s):  
Zhongjian Xie ◽  
Ruitao Lu ◽  
Yao Zhu ◽  
Minhua Peng ◽  
Taojian Fan ◽  
...  
Keyword(s):  
Liquid Phase ◽  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Organic Materials ◽  
2D Materials ◽  
The Family ◽  
2D Nanomaterials ◽  
Liquid Phase Exfoliation ◽  
Cellulose Nanosheets

Aim: The present study aims to apply the facile liquid-phase exfoliation (LPE) strategy to fabricate 2D organic materials and thus to broaden the family of biocompatible and multifunctional 2D materials. Materials & methods: 2D material-organic melanin and cellulose nanosheets were synthesized from black sesame hull using LPE. Photoluminescence and photothermal properties of the nanosheets were assessed, as well as stability and cell killing ability. Results: The prepared 2D nanoplatform exhibited broad and multiple photoluminescent emission bands. It also demonstrated efficient photothermal cancer therapy with excellent biocompatibility. Conclusion: The present study could open an avenue in exfoliating organic materials using the LPE strategy. This could make the fabrication of multifunctional 2D organic materials more efficient and broaden the family of biocompatible 2D nanomaterials.

Controlling the Morphology of Nanoflakes Obtained by Liquid-Phase Exfoliation: Implications for the Mass Production of 2D Materials

2020 ◽  
Vol 3 (12) ◽  
pp. 12095-12105
Author(s):  
Hélio Chacham ◽  
Joyce C. C. Santos ◽  
Flávia G. Pacheco ◽  
Diego L. Silva ◽  
Rozana M. Martins ◽  
...  
Keyword(s):  
Liquid Phase ◽  
Mass Production ◽  
2D Materials ◽  
Liquid Phase Exfoliation

Multiscale molecular thermodynamics of graphene-oxide liquid-phase exfoliation

2019 ◽  
Vol 21 (4) ◽  
pp. 1761-1772 ◽  
Author(s):  
Amir A. Farajian ◽  
Reza Mortezaee ◽  
Tim H. Osborn ◽  
Olga V. Pupysheva ◽  
Michael Wang ◽  
...  
Keyword(s):  
Free Energy ◽  
Graphene Oxide ◽  
Liquid Phase ◽  
Multiscale Modeling ◽  
Molecular Thermodynamics ◽  
2D Nanomaterials ◽  
Liquid Phase Exfoliation

Thermodynamics of 2D nanomaterials exfoliation in solution are analyzed by considering parallel, perpendicular, and edge routes for graphene-oxide as an example. Multiscale modeling is used to quantitatively assess and compare free energy changes for various surface coverages.

Disentangling the liquid phase exfoliation of two-dimensional materials: an “in silico” perspective

2020 ◽  
Vol 22 (39) ◽  
pp. 22157-22179
Author(s):  
Titas Kumar Mukhopadhyay ◽  
Ayan Datta
Keyword(s):  
Liquid Phase ◽  
Molecular Simulation ◽  
In Silico ◽  
2D Materials ◽  
Two Dimensional ◽  
Simulation Techniques ◽  
Recent Advances ◽  
Two Dimensional Materials ◽  
Liquid Phase Exfoliation ◽  
Shed Light

In this perspective article, recent advances in molecular simulation techniques have been reviewed to shed light on the complexity of liquid phase exfoliation of 2D materials.

Ultrafine transition metal dichalcogenide nanodots prepared by polyvinylpyrrolidone-assisted liquid phase exfoliation

2017 ◽  
Vol 5 (14) ◽  
pp. 2609-2615 ◽  
Author(s):  
Shan Zhang ◽  
Jing Li ◽  
Erkang Wang
Keyword(s):  
Liquid Phase ◽  
Transition Metal ◽  
Photothermal Therapy ◽  
Photothermal Effect ◽  
Transition Metal Dichalcogenide ◽  
Cell Toxicity ◽  
Liquid Phase Exfoliation

Ultrafine MoSe2 nanodots were prepared by polyvinylpyrrolidone (PVP)-assisted liquid phase exfoliation, which were further applied as efficient light-absorbing agent for photothermal therapy with negligible cell toxicity and appreciable photothermal effect.

Dispersant-assisted liquid-phase exfoliation of 2D materials beyond graphene

Nanoscale ◽  
2021 ◽  
Author(s):  
Chen-Xia Hu ◽  
Yuyoung Shin ◽  
Oliver Read ◽  
Cinzia Casiraghi
Keyword(s):  
Liquid Phase ◽  
2D Materials ◽  
Production Method ◽  
Future Research ◽  
Research Directions ◽  
2D Material ◽  
Wide Range ◽  
Water Based ◽  
Future Research Directions ◽  
Liquid Phase Exfoliation

Dispersant-assisted liquid-phase exfoliation allows the production of a wide range of water-based 2D material dispersions. This review provides an overview on this production method and also gives some perspectives on future research directions.

scholarly journals Preparation of TiH1.924 nanodots by liquid-phase exfoliation for enhanced sonodynamic cancer therapy

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Fei Gong ◽  
Liang Cheng ◽  
Nailin Yang ◽  
Yuehan Gong ◽  
Yanwen Ni ◽  
...  
Keyword(s):  
Liquid Phase ◽  
Cancer Therapy ◽  
Liquid Phase Exfoliation

Radar-like MoS2 nanoparticles as a highly efficient 808 nm laser-induced photothermal agent for cancer therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (37) ◽  
pp. 31031-31036 ◽  
Author(s):  
Zichen Huang ◽  
Yafei Qi ◽  
Dexin Yu ◽  
Jinhua Zhan
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Highly Efficient ◽  
Mos2 Nanoparticles

Radar-like MoS2 nanoparticles were demonstrated and used as highly efficient photothermal therapy for cancer in vitro and in vivo.

Surface Tension Components Based Selection of Cosolvents for Efficient Liquid Phase Exfoliation of 2D Materials

Small ◽  
2016 ◽  
Vol 12 (20) ◽  
pp. 2741-2749 ◽  
Author(s):  
Jianfeng Shen ◽  
Jingjie Wu ◽  
Man Wang ◽  
Pei Dong ◽  
Jingxuan Xu ◽  
...  
Keyword(s):  
Surface Tension ◽  
Liquid Phase ◽  
2D Materials ◽  
Liquid Phase Exfoliation ◽  
Selection Of

scholarly journals NDs@PDA@ICG Conjugates for Photothermal Therapy of Glioblastoma Multiforme

Biomimetics ◽  
2019 ◽  
Vol 4 (1) ◽  
pp. 3 ◽  
Author(s):  
Damian Maziukiewicz ◽  
Bartosz Grześkowiak ◽  
Emerson Coy ◽  
Stefan Jurga ◽  
Radosław Mrówczyński
Keyword(s):  
Glioblastoma Multiforme ◽  
Cancer Therapy ◽  
Brain Tumors ◽  
Indocyanine Green ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Survival Rates ◽  
Modern Medicine ◽  
New Ideas

The growing incidence of cancer is a problem for modern medicine, since the therapeutic efficacy of applied modalities is still not satisfactory in terms of patients’ survival rates, especially in the case of patients with brain tumors. The destructive influence of chemotherapy and radiotherapy on healthy cells reduces the chances of full recovery. With the development of nanotechnology, new ideas on cancer therapy, including brain tumors, have emerged. Photothermal therapy (PTT) is one of these. It utilizes nanoparticles (NPs) that can convert the light, preferably in the near-infrared (NIR) region, into heat. In this paper, we report the use of nanodiamonds (NDs) conjugated with biomimetic polydopamine (PDA) and indocyanine green (ICG) for glioblastoma cancer PTT therapy. The obtained materials were thoroughly analyzed in terms of their PTT effectiveness, as well as their physicochemical properties. The performed research demonstrated that NDs@PDA@ICG can be successfully applied in the photothermal therapy of glioblastoma for PTT and exhibited high photothermal conversion efficiency η above 40%, which is almost 10 times higher than in case of bare NDs. In regard to our results, our material was found to lead to a better therapeutic outcome and higher eradication of glioblastoma cells, as demonstrated in vitro.

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