scholarly journals Quantum Dots: Method of Preparation and Biological Application

2019 ◽  
Vol 9 (4-s) ◽  
pp. 670-672 ◽  
Author(s):  
Amol Gomase ◽  
Sagar Sangale ◽  
Akshay Mundhe ◽  
Pravin Gadakh ◽  
Vikrant Nikam

Quantum dots are inorganic semiconductor crystal of nanometer size which having distinctive conductive property depend on its size & shape. After administration of quantum dots parentally they identify target and bound them. Also quantum dots having light emitting property depend on size & shape. Quantum dots are prepared by chemical synthesis method include both organic & water phase synthesis & also by top- bottom approach. Tumor cell targeting & detection of pathogen & toxin are the main application of quantum dots & also in targeting drug delivery system. This review provides the overview of method of preparation of quantum dots & its biological application. Keywords: Quantum dot, targeting drug delivery, biological application

2013 ◽  
Vol 706-708 ◽  
pp. 230-233
Author(s):  
Wei Liu ◽  
Xian Lan Chen ◽  
Ju Cheng Zhang ◽  
Yun Hui Long ◽  
Ling Shi ◽  
...  

With water as the medium, PVP as stabilizer and ammonia as complexing agents and adjusting pH value of the solution, we report an all-aqueous synthesis of highly photoluminescent and stable ZnS quantum dots (QDs) by water-phase synthesis reaction between ZnCl2 and NaS at different temperatures and times. The optimal reaction conditions of PVP-capped ZnS QDs were obtained through experiment as follows: the concentration ZnCl2 and NaS solution both are 1 mM, (PVP):(ZnCl2) = 0.0167 (v/v), (NH3):(ZnCl2)=1:300 (v/v), the optimal reaction temperature is 40 °C, the optimal reaction time is 30 min. With ammonia as complexing agents, Zn(OH)2 can dissolve in ammonia and form to complex ions ((Zn(NH3)4)2+), which make Zn2+ release slowly to control the nucleus growth rate of ZnS, thus obtain small size of nanoparticles. The fluorescence spectra shows that the emission peaks of ZnS QDs around ~395 nm and ~470 nm on the emission spectra, which are consistent with literatures, so nano-ZnS QDs was synthesized successfully in this paper.


2020 ◽  
Vol 15 (5) ◽  
pp. 599-606
Author(s):  
Jian Xu ◽  
Hongxiang Zhang ◽  
Chunxia Wu ◽  
Jun Dai

In this article, we reported the synthesis method of stable CsPbX3@SiO2 quantum dots using cesium acetate instead of cesium carbonate. The results showed that CsPbX3@SiO2 presents good crystallinity and excellent luminescence properties. The coating layer of SiO2 on the CsPbX3 quantum dots surface blocks the air and water contact and suppresses anion exchange between the quantum dots, which dramatically enhances the stability. White light-emitting diode devices are manufactured by integrating the green CsPbBr3@SiO2 quantum dots and red CsPbBr1 I2@SiO2 quantum dots on the blue GaN chips. The devices show stable white light emission with Commission Internationale de L'Eclairage color coordinates (0.3511, 0.3437), and the white light intensity keeps unchanged after continuously working for 16 hours. The results indicate that CsPbX3@SiO2 quantum dots can be an ideal down-conversion fluorescent material for white light-emitting diode devices.


2015 ◽  
Vol 3 (45) ◽  
pp. 11965-11973 ◽  
Author(s):  
O. Arslan ◽  
L. Belkoura ◽  
S. Mathur

Facile solution-phase synthesis of remarkably luminescent and monodisperse oleate-capped ZnO nanoparticles with high colloidal stability was developed.


2019 ◽  
Vol 7 (14) ◽  
pp. 4244-4249 ◽  
Author(s):  
Rui Cheng ◽  
Fucheng Li ◽  
Jiahui Zhang ◽  
Xingjin She ◽  
Yi Zhang ◽  
...  

An easy-to-perform interfacial synthesis method is demonstrated to achieve amphiphilic quantum dots with a high photoluminescence quantum yield, which are useful for high-color-quality light-emitting applications.


2012 ◽  
Vol 581-582 ◽  
pp. 574-577 ◽  
Author(s):  
Wei Liu ◽  
Xian Lan Chen ◽  
La Shi Yang ◽  
Ju Cheng Zhang ◽  
Ping Yi ◽  
...  

Hypocrellin A is organic dyes with more superior visible light performance, which has resistant tumor activity and becomes widely accepted. In this paper, acetone is used as solvent to extract, separate and purify the hypocrellin A. With ZnCl2 and Na2S as raw material, ZnS Quantum dots (QDs) were prepared by water-phase synthesis method under the role of the magnetic stirrer. Fluorescence detection results showed that the optimum pH of the ZnS QDs and HA solution close to neutral (6.86). The fluorescence quenching of hypocrellin A is most obvious as the ZnS QDs was added, because of the strong interaction was generated between HA and ZnS QDs, resulting in the fluorescence quenching.


Author(s):  
Prashant Malik ◽  
Neha Gulati ◽  
Raj Kaur Malik ◽  
Upendra Nagaich

Nanotechnology deal with the particle size in nanometers. Nanotechnology is ranging from extensions of conventional device physics to completely new approaches based upon molecular self assembly, from developing new materials with dimensions on the nanoscale to direct control of matter on the atomic scale. In nanotechnology mainly three types of nanodevices are described: carbon nanotubes, quantum dots and dendrimers. It is a recent technique used as small size particles to treat many diseases like cancer, gene therapy and used as diagnostics. Nanotechnology used to formulate targeted, controlled and sustained drug delivery systems. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials and as devices like drug delivery, diagnostic, imaging and biosensor materials. Pharmaceutical nanotechnology has provided more fine tuned diagnosis and focused treatment of disease at a molecular level.    


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