scholarly journals “Air Polishing and CHX Effects in Addition to Subgingival Ultrasonic Instrumentation on Clinical Periodontal Parameters: A Randomised Clinical Trial”

2020 ◽  
Vol 6 (6) ◽  
Author(s):  
Ayse Caygur
Keyword(s):  
Randomised Clinical Trial ◽  
Periodontal Pocket ◽  
Control Group ◽  
Distilled Water ◽  
Beneficial Effects ◽  
Air Polishing ◽  
Probing Depth ◽  
Ultrasonic Devices ◽  
Hand Instrumentation ◽  
And Control

Objectives:  This study was performed to investigate the efficacy of using glycine powder air-polishing (GPAP) or  antiseptics (CHX) adjunctively to scaling and  root planing (SRP) in the treatment of periodontitis. Methods: In this trial, ninety patients (between 28-80 years old) who had at least three teeth with 3 to 7- mm periodontal pockets, were ıncluded from the Department of Periodontology. The patients were divided into three groups randomly. In the control group ultrasonic instrumentation was performed with distilled water and hand instrumentation, in the CHX group ultrasonic instrumentation was performed with CHX and hand instrumentation, in the GPAP group in addition to SRP with ultrasonic performed with distilled water and hand instrumentation, GPAP was performed for 10 seconds per periodontal pocket using a Perio-Flow device.  All treatments were performed in one session.  Resuls: The scores of  plaque index(PI),gingival index (GI), probing depth (PD), bleeding on probing (BOP) and clinical attachement level (CAL) were decreased in all groups after 1 month and the results were statistically significant in intergoup comparisions. PI and CAL scores were statistically significant in intragroup comparisions in GPAP group. Altough GI, PD and BOP scores were lower in the GPAP group than CHX and control group, the differences after 1 month were not statistically significant.  Conclusion: Within the limits of this study, it was seen that SRP was effective alone in the treatment of periodontitis. However, using a CHX with ultrasonic devices has little beneficial effects on periodontal parameters when compared with control and GPAP groups. GPAP groups was found more effectively in PI and CAL scores.

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy: a randomized clinical trial

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Holger F. R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Nonparametric Tests ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

Abstract Background This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods Fourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n = 21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n = 21). They were analyzed for the clinical variables BOP (primary outcome at six months), probing depth (PD), attachment level, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results In both groups, the clinical variables PD, attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months versus baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only. Clinical relevance The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL.

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

2020 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Nonparametric Tests ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

Abstract Background: This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods:Forty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n=21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n=21). They were analyzed for the clinical variables BOP (primary outcome at six month), probing depth (PD), attachment level (AL), four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results: In both groups, the clinical variables probing depth (PD), attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5mm was significantly lower in the test group than in the control group after six months. At six months vs. baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions:Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5mm when compared with subgingival instrumentation only. Clinical relevanceThe adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery.

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

2020 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Nonparametric Tests ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

Abstract Background: This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods: Fourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n=21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n=21). They were analyzed for the clinical variables BOP (primary outcome at six month), probing depth (PD), attachment level (AL), four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results: In both groups, the clinical variables probing depth (PD), attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5mm was significantly lower in the test group than in the control group after six months. At six months vs. baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions: Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5mm when compared with subgingival instrumentation only. Clinical relevance: The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration: The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId =trial.HTML&TRIAL

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

2020 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Clinical Variable ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Significant Difference

Abstract Background: This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods: Fourty-two individuals with periodontitis receiving nonsurgical periodontal therapy by SI without (controls, n=21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n=21) were analyzed for clinical variables, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results: In both groups, the clinical variables probing depth (PD), attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months vs. baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group but not in the controls. There was no further significant difference of any clinical and non-clinical variable between both groups at three and six months after SI. Conclusions: Subgingival instrumentation with adjunctive erythritol air-polishing powder may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only. Clinical relevanceThe adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI. Trial registration: The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId =trial.HTML&TRIAL

scholarly journals Efeito de imunodulador glutamina e probiótico pool de Lactobacillus na atenuação dos sintomas e crises de asma em crianças

2020 ◽  
Vol 34 (4) ◽  
pp. 346-354
Author(s):  
Michele Honicky ◽  
João Paulo Zattar ◽  
Mariana Saciloto ◽  
Mariana Abe Vicente Cavagnari ◽  
Claudia Nodari ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Clinical Characteristics ◽  
Glutamine Supplementation ◽  
Control Group ◽  
Beneficial Effects ◽  
Asthma Symptoms ◽  
Asthma Attack ◽  
Asthma In Children ◽  
And Control

Introduction: Immunomodulator glutamine and probiotic Lactobacillus at certain doses have beneficial effects by modulation of the immune system and may assist in the integrity of therespiratory system. However, studies about the effects of glutamine or Lactobacillus pool on the prevention and control of asthma in children are still scarce. The aim of study was to evaluate the effect of the use of glutamine and Lactobacillus pool on the attenuation of clinical asthma symptoms in children. Methods: Longitudinal study, 45 children with medical diagnosis of asthma distributed in three groups: control group (C), glutamine group (G), Lactobacillus group (L). Group G was supplemented with L-glutamine powder (0.3 g/kg/day). Group L used a pool of Lactoba- cillus (Lactobacillus casei, paracasei, rhamnosus, acidophilus and Bifidobacterium lactis) (2 g/day). Group C received no glutamine or Lactobacillus pool. Clinical characteristics and symptoms of respiratory diseases were assessed by study-specific anamnesis and ISSAC Questionnaire (to obtain diagnostic scores and asthma symptoms) for 4 months. To test for differences between groups, the ANOVA test with Tukey post-hoc test was used. It was considered significant p <0.05. Results: Initial ISSAC score was (C=8.67±1.77, L=7.80±1.52 and G=8.00 ± 1.46, p=0.31). At the first follow-up, the ISSAC score indicated that group G had improvement in the clinical characteristics of asthma (C=6.47±2.29, L = 5.07±2.28, G = 4.00±1.73, p <0.05), as also occurred in the following months until the last follow-up (C=5.93±2.28, L=5.13±2.13, G=4.00±1.96, p<0.05). After supplementation, group G presented lower mean duration of asthma attack (p=0.01), lower number of asthma attack (p<0.05), lower prevalence of typical asthma symptoms, as cough and wheezing (p<0.05). Conclusion: Glutamine supplementation attenuated the typical asthma symptoms, while the use of Lactobacillus pool did not attenuate the symptoms. Glutamine may be a new strategy for prevention and control of asthma in children.

scholarly journals Clinical and Radiographic Characteristics of Endoperiodontitis in Patients with Chronic Generalized Periodontitis

2017 ◽  
pp. 13-20
Author(s):  
L.N. Dedova ◽  
Yu.L. Denisova ◽  
N.I. Rossenik
Keyword(s):  
Prognostic Significance ◽  
Periodontal Pocket ◽  
Cone Beam ◽  
Radiographic Examination ◽  
Control Group ◽  
Diagnostic Efficacy ◽  
Probing Depth ◽  
Furcation Involvement ◽  
Total Accuracy

The article presents modern data on the priority clinical and radiographic signs of endoperiodontitis in patients with chronic generalized periodontitis. The aim of the research was to determine the complex of clinical and radiographic methods for diagnosing the patients with chronic generalized periodontitis in conjunction with a localized complex endoperiodontitis. Objects and methods. The research included the clinical and radiographic examination of 100 almost healthy patients aged 35-44 years. The study group consisted of 50 patients with chronic generalized periodontitis of moderate severity in conjunction with a localized complex endoperiodontitis (100 teeth). The control group was represented by 50 patients without periodontal pathology. The diagnosis endoperiodontitis was made according to the classification of professor L.N. Dedova (2012). Result and discussion. Clinical studies revealed chronic localized endoperiodontitis which led to 13.6 times decrease of pulp vitality and increase in the probing depth of the periodontal pocket by 4.84 ± 1,34 mm. CBCT was characterized by greater than IOR and OPG sensitivity (98%), 96% specificity, with a total accuracy of 97% and 24.5 times higher prognostic significance. Conclusion. The main methods of diagnosing localized complex endoperiodontitis are the electric pulp test and probing the periodontal pockets that has 4.2 times higher prognostic significance compared to gingival index, bleeding on probing, suppuration from periodontal pockets, migration of teeth, positive percussion, tooth mobility, furcation involvement and formation of acute periodontal abscesses. The additional method of diagnosing the localized complex endoperiodontitis is cone-beam computed tomography that has the diagnostic efficacy 96‒98% compared to intraoral radiography (42‒44%) and orthopantomography (52‒66%).

scholarly journals Effects of enteral glutamine on gut mucosal protein synthesis in healthy humans receiving glucocorticoids

2000 ◽  
Vol 278 (5) ◽  
pp. G677-G681 ◽  
Author(s):  
Corinne Bouteloup-Demange ◽  
Sophie Claeyssens ◽  
Celine Maillot ◽  
Alain Lavoinne ◽  
Eric Lerebours ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Synthesis Rate ◽  
Control Group ◽  
Fed State ◽  
Beneficial Effects ◽  
Healthy Humans ◽  
Significant Difference ◽  
Equivalent Control ◽  
Mucosal Protein ◽  
And Control

In hypercatabolic patients, the beneficial effects of glutamine on gut mucosa could be partly due to a stimulation of protein synthesis. The fractional synthesis rate (FSR) of gut mucosal protein was measured in four groups of healthy volunteers treated with glucocorticoids for 2 days. Two groups were studied in the postabsorptive state while receiving glutamine or a nitrogen equivalent (control) and two groups in the fed state with or without glutamine, using a 5-h intravenous infusion of [13C]leucine, [2H5]phenylalanine, and cortisone. After nutrient and tracer infusion, duodenal biopsies were taken. In the postabsorptive state, FSR of gut mucosal protein were 87 and 76%/day in the control group and 130% ( P = 0.058 vs. control) and 104% ( P = 0.17 vs. control)/day in the glutamine group, with leucine and phenylalanine as tracers, respectively. During feeding, FSR did not increase and no significant difference was observed between glutamine and control groups. Overall, FSR of the four groups were two- to threefold higher than those obtained previously in healthy humans, suggesting that glucocorticoids may increase gut mucosal protein synthesis. However, in this situation, a moderate enteral glutamine supply failed to demonstrate a significant effect on gut mucosal protein synthesis in the postabsorptive state and during feeding.

scholarly journals The Effectiveness of Psychological Workshops for Coaches on Well-Being and Psychomotor Performance of Children Practicing Football and Gymnastics

2021 ◽  
pp. 586-593
Author(s):  
Dominika Wilczyńska ◽  
Anna Łysak-Radomska ◽  
Magdalena Podczarska-Głowacka ◽  
Wojciech Skrobot ◽  
Katarzyna Krasowska ◽  
...  
Keyword(s):  
Psychomotor Performance ◽  
Well Being ◽  
Control Group ◽  
Self Reflection ◽  
Beneficial Effects ◽  
Specific Effects ◽  
Seven Principles ◽  
Before And After ◽  
Study Participants ◽  
And Control

Coach workshops based on seven principles (inspiration, explanation, expectation, support, reward, appreciation, growth and winning) enhance the sport experience of adult athletes. Therefore, we have investigated the effects of such workshops with coaches of child athletes. Study participants were coaches of 57 9- to 12-year old girls (practicing gymnastics) and boys (practicing football). Three coaches of 28 children attended three workshops over 12 weeks, while a control group of 5 coaches of 29 children attended no workshops. Measures of well-being and psychomotor performance were taken on the children before and after the intervention; differences in mean changes between intervention and control groups were adjusted for baseline, standardized, and assessed with a conservative magnitude-based decision method. There were clear substantial effects of the workshop on motivation averaged across several dimensions (girls, large, most likely beneficial), on a decision test (boys, small-moderate, very likely beneficial), on state anxiety self-reflection (girls, moderate, likely harmful), and on reaction time (boys, small, possibly harmful). The beneficial effects of the workshop in this pilot study are encouraging, but the unclear and potentially harmful effects and the roles of presenter- and coach-specific effects need to be investigated further with a representative sample of coaches and more children before the workshop is recommended for implementation.

scholarly journals Effect of acidulated phosphate fluoride application on microhardness of glass ionomer cement

2015 ◽  
Vol 27 (2) ◽  
Author(s):  
Mohammad Azrul Izzudin ◽  
Elin Karlina ◽  
Ratna Indriyanti
Keyword(s):  
Glass Ionomer Cement ◽  
Hardness Test ◽  
High Viscosity ◽  
Control Group ◽  
Distilled Water ◽  
Test Results ◽  
Glass Ionomer ◽  
Significant Difference ◽  
Experimental Laboratory ◽  
And Control

Introduction: Acidulated phosphate fluoride (APF) gels are commonly used as preventive caries materials in paediatric dentistry while glass ionomer cements (GICs) are widely used as a restorative material. The purpose of this study was to determine the effect of acidulated phosphate fluoride application towards the microhardness of GIC. Methods: This study was an experimental laboratory study where ten specimens were prepared from high viscosity GIC, which was Fuji IX. Specimens were stored in 50 ml distilled water at first 24 hours at 37°C, and then specimens were divided into fluoride group which was immersed in 25 ml of 1.23 % APF gel and control group which was stored 25 ml distilled water for 24 hours at 37°C. The Micromet II Microhardness Tester, Buehler, IL, USA that was standardised for Vickers hardness test was used to test the specimens at 100-gram load. Data were analysed using the t-test comparison test. Results: The level of microhardness of the fluoride group (14.34) was much lower compared to the control group (43.21) with a highly significant difference (p<0.01). Conclusion: The application of 1.23% APF gel on high viscosity GIC reduces the microhardness level compared to the control group.

scholarly journals Wound healing under the effect of iodine cadexomer in rats

2012 ◽  
Vol 27 (12) ◽  
pp. 874-879 ◽  
Author(s):  
Ester Verônica Brustolin ◽  
Thelma Larocca Skare ◽  
Paulo Afonso Nunes Nassif ◽  
Maria de Lourdes Pessole Biondo-Simões ◽  
Manoel Alberto Prestes ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Statistical Significance ◽  
Healing Process ◽  
Microscopic Analysis ◽  
Systemic Absorption ◽  
Control Group ◽  
Distilled Water ◽  
Free T4 ◽  
Beneficial Effects ◽  
The Right

PURPOSE: To assess vthe action of iodine cadexomer in the healing process of surgical wounds in rats and if cytotoxicity occurs with the systemic absorption of iodine. METHODS: Thirty six Wistar rats were used and performed 53 wounds with surgical punch of 6 mm diameter on them. Two lesions were made diametrically opposed on groups with distilled water (GAD) and sodium chloride (GCS); on the right lesions were used bandage with distilled water and on the left ones dressing with sodium chloride. In cadexomer iodine (GCI) group, a punch injury was made only on the left side and the dressing was carried out with cadexomer iodine. The groups were divided in two sub-groups according to the day of death (7 and 14). Microscopically was used H&E staining, through which the inflammation could be observed and also the neovascularization. Staining with Masson trichrome studied fibrosis. TSH and free T4 were used for absorption recognition of iodine, and its toxic potential was performed before death with the animal anesthetized. RESULTS: Microscopic analysis showed more marked intensity of inflammation in group GAD, subgroup 14 days. Neovascularization showed be discrete in GCS sub-group 14 days. Fibrosis was more pronounced in the group GCI. Comparing the types of treatment, there was statistical significance between groups GCI and GCS (p<0.013). The TSH and T4, showed no difference between the control group and GCI in relation to the absorption of iodine. In evaluating the GCI and control groups, within each treatment, statistical significance was found between them (p<0.001) when compared the days of observation. CONCLUSION: Cadexomer iodine had beneficial effects in all phases of the healing process without cytotoxicity due iodine absorption.

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