scholarly journals Analisis Komposisi dan Distribusi Batu Empedu di Laboratorium Fakultas Kedokteran Universitas Indonesia (FKUI) Jakarta

2020 ◽  
Vol 9 (1) ◽  
pp. 19-26
Author(s):  
Tri Retno Yova Meidina ◽  
Ninik Mudjihartini ◽  
Dwirini Retno Gunarti ◽  
Yulhasri Yulhasri ◽  
Syarifah Dewi ◽  
...  

Abstrak Batu empedu merupakan penyakit yang banyak ditemukan di Indonesia. Analisis komposisi batu empedu penting untuk mengetahui penyebab, dasar metabolisme pembentukannya, faktor risiko, serta untuk edukasi diet terhadap pasien. Komposisi batu empedu tersebut dapat dipengaruhi oleh berbagai faktor termasuk usia dan jenis kelamin. Sampai saat ini belum terdapat data analisis komposisi dan distribusi batu empedu di Jakarta. Dengan demikian, penelitian ini bertujuan untuk menganalisis komposisi dan distribusi batu empedu yang dihubungkan dengan usia dan jenis kelamin. Penelitian ini merupakan penelitian cross-sectional menggunakan 230 data sekunder hasil analisis komposisi batu empedu di Laboratorium Biokimia dan Biologi Molekuler FKUI dalam periode 3 tahun terakhir (tahun 2017 – 2019). Analisis batu dilakukan dengan uji Salkowski untuk menilai kolesterol serta uji kalsium, karbonat, Fe, pigmen empedu, dan fosfat. Hasil penelitian menunjukkan bahwa batu empedu sebesar 1,3% merupakan batu murni dan 98,7% merupakan batu campuran. Komposisi terbanyak pada batu campuran yaitu kolesterol (83,91%). Batu empedu paling banyak ditemukan pada perempuan kelompok usia 40—49 tahun (27%). Terdapat hubungan komposisi kolesterol dengan usia (p<0,05) namun tidak terdapat hubungan (p>0,05) dengan jenis kelamin (p>0,05). Kesimpulan dari penelitian ini yaitu kolesterol merupakan penyusun komposisi batu empedu yang terbanyak yang berhubungan dengan usia, namun tidak berhubungan dengan jenis kelamin. Kata kunci: Batu Empedu, Distribusi, Komposisi, Kolesterol Abstract Gallstones are a disease that is commonly found in Indonesian. Analysis of the composition of gallstones is important to determine the etiology, the metabolic basis of its formation, risk factors, and to educate for the patient's diet. The composition of gallstones can be influenced by various factors including age and sex. Until now there is no data analysis of the composition and distribution of gallstones in Jakarta. Thus, this study aims to analyze the composition and distribution of gallstones that are associated with age and sex. This study is a cross-sectional study using 230 secondary data from the analysis of the composition of gallstones in the Laboratory of Biochemistry and Molecular Biology of FMUI in the last 3 years period (2017 - 2019). Stone analysis was carried out with the Salkowski test to assess cholesterol and also calcium, carbonate, Fe, bile pigment, and phosphate assays. The results showed that 1.3% gallstones were pure stones and 98.7% were mixed stones. The most composition in mixed stones is cholesterol (83.91%). Gallstones are most commonly found in women in the age group of 40-49 years (27%). There is a correlation between cholesterol composition with age (p <0.05) but there is no relationship (p> 0.05) with gender (p> 0.05). This study concluded that cholesterol was the most common constituent of gallstone. Its levels increased with age and did not differ significantly between genders. Keywords: Gallstone, Composition, Distribution, Cholesterol

2020 ◽  
Vol 54 (5) ◽  
Author(s):  
Edward James R. Gorgon

Objective. The Timed Up-&-Go Test (TUGT) is a clinically useful measure that has been widely used in practice toassess functional mobility in older people. Interpretation of TUGT scores relies on appropriate reference values.This study aimed to describe preliminary age- and sex-related reference values for the TUGT for Filipinos aged60–79 years. Methods. This is a descriptive cross-sectional study. We included Filipino adults aged 60–79 years, with no significantdisability, and resided in metropolitan areas in the National Capital Region and rural communities in southernLuzon. All participants completed the TUGT. Data were analyzed descriptively and reported as means, standarddeviations, and 95% confidence intervals. Results. A total of 156 community-dwelling older adults participated in the study with mean age (SD) of 68 (5)years. The majority were women (103/156, 66%). Mean (SD) TUGT score for all participants was 11.0 (2.4) seconds.Overall, men completed the test faster compared to women, and individuals in the 60–69 years age group hadshorter completion times than those in the 70–79 years age group. Conclusion. In the absence of definitive reference values for older Filipino adults, this study provides preliminaryguidance for interpreting TUGT performance for the purposes of screening and monitoring functional mobilityimpairments in this population.


2019 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Wiegmann ◽  
Felsenberg ◽  
Gast ◽  
Börst ◽  
Armbrecht ◽  
...  

Reference values of sway parameters have not been published for the Leonardo mechanograph® so far. The aim of this cross-sectional study was to determine normative values on postural control measured by the force plate Leonardo Mechanograph® and to analyze the influence of age and sex on balance performance. A set of standardized standing positions with eyes opened (Romberg, semi-tandem, tandem, unipedal standing) was carried out. Analysis of covariance (ANCOVA) was used to detect age-and sex-related differences in center of pressure (COP) parameters (path length, velocity, elliptical area, anterior-posterior, and medio-lateral directions). Measurements were available for 570 subjects aged 20–86 years. Statistical analysis showed a high effect of age group on postural control (partial n² between 0.1 and 0.4) with a U-shaped dependency between postural control and age for all area- and path-related COP parameters, with the largest sway in the youngest (aged 20–40) and the oldest age group (aged 60–86). For velocity of COP, a linear deterioration with increasing age was found. Medio-lateral components of COP are likely to indicate the extent of postural control. Significant sex differences were not clearly supported by current findings. Age- and sex-related normative values are a useful resource for diagnostic, research, and training.


2021 ◽  
Vol 10 (4) ◽  
pp. 201-207
Author(s):  
Humaira Mahmood ◽  
Mehwish Riaz ◽  
Naila Azam ◽  
Zaffar Iqbal ◽  
Saira Maroof

Background: Current study aim to describe epidemiological, clinical and  demographic features in patients confirmed to have COVID-19 in Balochistan Methods: This descriptive cross sectional Study was conducted during months of March and April 2020 based on the secondary data available regarding COVID-19 positive patients from the health service records of Government of Balochistan quarantine centers and hospitals during this period. Data was analyzed by using Excel and SPSS version 23. Mean and standard deviations are used for continuous variables like age and duration of stay (of recovered patients), while frequencies and percentages were used to describe age categories, point of entry and current status. Age specific case fatality rate is calculated by keeping deaths in numerator and confirmed cases in denominator. Results: Mean age of respondents was 35.3±16.12 years , two third of the study population i.e,652(76.3%) were males,353 (40.6)% were in the age group 30-49 years and 417(48.9%) had history of contact with COVID-19 case. Overall case fatality rate was 1.87% and Age Specific Mortality Rate was found to be highest (30%) in age group 70 years and above Conclusion: The epidemiologic behavior of COVID-19 infection introduced in Pakistani population from neighboring country has responded differently in community spread among different ethnic groups represented in different provinces of Pakistan. The case fatality ratios among Baloch ethnic group were much lower than international COVID-19 case responses


2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13


1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21


2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.


2020 ◽  
Vol 11 (01) ◽  
Author(s):  
Priyanka Beniwal ◽  
Chandrakala Singh

Aging is a series of processes that begin with life and continue throughout the lifecycle. It represents the closing period in the lifespan, a time when the individual looks back on life, lives on past accomplishments and begins to finish off his life course. It represents the accumulation of changes in person over time. The study aims to investigate the health status of senior citizens. The present study was carried out in Hisar and Sirsa district of Haryana state. A total of 400 elderly equally representing both males and females of age group 65-70 years were selected randomly for the study. Modified inventory developed by Khan and Lal (2011) was used to assess health status of senior citizens. The results of the study elucidated that health status of senior citizens depicted that 54.25 per cent of the total respondents had average health status followed by good (25.25%) and poor health status (20.50%). The most common health problems reported by the senior citizens were joint pains, back pains, blood pressure, and chest pain etc. Gender wise comparison of total sample further pointed out that females were poor in their health against males.


2012 ◽  
pp. 129-134
Author(s):  
Thi Lan Tran ◽  
Thi Huong Le ◽  
Xuan Ninh Nguyen

Objectives: Assess the nutritional status, worm infection status and some related factors among children aged 12-36 months of Dakrong district, Quang Tri province. Subject and method: A cross sectional study was carried out in 2010, in 680 children aged 12-36 months in 4 communes of Dakrong district, Quang Tri province. Results: The malnutrition rate was 55.0% for underweight, 66.5% for stunting and 16.2% for wasting. The prevalence of malnutrition increases by age group. The prevalence of worm infection was 31.6%, the highest prevalence was belong to Ascaris infection (24.6%), followed by Hookworm and Trichuris (6.5% and 6.2%, respectively). The prevalence of worm infection among children under two is very high (27.0%). The prevalence of worm infection was distributed quite equally between the malnutrition children group and normal children group. Recommendation: Early deworming forchildren from 12 months should be considered as important strategy against the malnutrition of children in Dakrong district, Quang Tri province


2020 ◽  
Vol 2 (CSI) ◽  
pp. 12-18
Author(s):  
Ali Al-Rubaye ◽  
Dhurgham Abdulwahid ◽  
Aymen Albadran ◽  
Abbas Ejbary ◽  
Laith Alrubaiy

Background: There has been a rapid rise in cases of COVID-19 infection and its mortality rate since the first case reported in February 2020. This led to the rampant dissemination of misinformation and rumors about the disease among the public. Objectives: To investigate the scale of public misinformation about COVID-19 in Basrah, Iraq. Methods: A cross-sectional study based on a 22-item questionnaire to assess public knowledge and understanding of information related to the COVID-19 infection. Results: A total of 483 individuals completed the questionnaire. The most frequent age group was 26–35 years (28.2%); there were 280 (58%) males and 203 (42%) females. Of the participants, 282 (58.4%) were with an education level below the Bachelor’s degree, 342 (70.8%) were married, and 311 (64%) were living in districts in Basra other than the central district. Overall, 50.8% (11.8/ 22 * 100%) of individuals had the correct information regarding COVID-19. There was a significant association between the level of COVID-19 related misinformation and participants’ educational levels and occupation (p <0.05). However, there was no significant difference found across sex, age group, marital state, and area of residence. Conclusions: Misinformation related to COVID-19 is widely spread and has to be addressed in order to control the pandemic. Keywords: COVID-19, misinformation, knowledge, Iraq


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