scholarly journals Pengendalian Diabetes Melitus Tipe 2 pada Pasien di Puskesmas Jayabaru Kota Banda Aceh

2018 ◽  
Vol 28 (4) ◽  
pp. 239-246
Author(s):  
Nur Ramadhan ◽  
Nelly Marissa ◽  
Eka Fitria ◽  
Veny Wilya
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Plasma Glucose ◽  
Good Control ◽  
Cross Sectional ◽  
Banda Aceh ◽  
Diabetes Melitus

Diabetes Mellitus (DM) is a metabolic disease that affects many people of the world, including Indonesia. To prevent complications, a good control of DM is needed by patients, one of them is controlling blood sugar and keeping blood pressure stable. DM is reported in Banda Aceh as one of diseases with the highest number of visits every year. The purpose of this study was to determine the achievements of DM control by patients with type 2 diabetes mellitus in Puskesmas Jayabaru Banda Aceh. The study used a cross sectional design and a sample of 85 patients with type 2 diabetes mellitus in Puskesmas Jayabaru in 2015. The results showed 81.2% HbA1c value ≥ 7%, 80% fasting plasma glucose (FPG) ≥ 100 mg/dl, 85.9% of the value post prandial plasma glucose ≥ 140 mg/dl and 58.8% blood pressure ≥ 130 mmHg. Of the 85 patients only 7 showed good DM control results. This illustrates that DM control achievement is still below the cut-off value set by PERKENI. Counseling to patients and families is needed to improve the management of type 2 DM by patients. Abstrak Abstrak Diabetes Melitus (DM) merupakan penyakit metabolik yang banyak diderita penduduk dunia, termasuk Indonesia. Untuk mencegah terjadi komplikasi diperlukan pengendalian DM yang baik oleh penderita, salah satunya dengan mengontrol gula darah dan menjaga tekanan darah tetap stabil. Penyakit DM dilaporkan di Kota Banda Aceh sebagai salah satu penyakit dengan angka kunjungan terbanyak setiap tahun. Tujuan penelitian ini untuk mengetahui capaian pengendalian DM oleh penderita DM tipe 2 di wilayah kerja Puskesmas Jayabaru Kota Banda Aceh. Penelitian menggunakan desain potong lintang dan sampel berjumlah 85 orang penderita DM tipe 2 di Puskesmas Jayabaru tahun 2015. Hasil penelitian menunjukkan 81,2% nilai HbA1c ≥ 7%, 80% nilai GDP ≥ 100 mg/dl, 85,9% nilai GD 2 jam PP ≥ 140 mg/dl, 58,8% dan tekanan darah ≥ 130. Dari 85 pasien hanya tujuh orang yang menunjukkan hasil pengendalian DM yang baik. Hal ini menggambarkan bahwa capaian pengendalian DM masih di bawah nilai cut off yang ditetapkan Perkumpulan Endokrinologi Indonesia (PERKENI). Penyuluhan kepada pasien dan keluarga sangat dibutuhkan untuk memperbaiki pengelolaan DM tipe 2 oleh penderita.

scholarly journals Hubungan Antara Tekanan Darah Sistolik Dengan Kadar Hdl Kolesterol Pada Pasien Diabetes Melitus Tipe 2 Di Klinik Arafah Lampung Tengah

2021 ◽  
Vol 1 (4) ◽  
pp. 307-314
Author(s):  
Toni Prasetia ◽  
Firhat Esfandiari ◽  
Sandhy Arya Pratama ◽  
Ikbal Zaenur Ridwan
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Systolic Blood Pressure ◽  
Hdl Cholesterol ◽  
Cross Sectional ◽  
Cholesterol Levels ◽  
Diabetes Melitus

ABSTRACT: RELATIONSHIP BETWEEN SYSTOLIC BLOOD PRESSURE AND HDL CHOLESTEROL LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS IN ARAFAH CLINIC, CENTRAL LAMPUNG Background: Hypertension is a major risk factor for type 2 Diabetes Mellitus, hypertension can make cells insensitive to insulin, so blood sugar levels can also be disrupted. Dyslipidemia causes constriction in blood vessels or atherosclerosis which can aggravate hypertension or diabetes mellitus. Meanwhile, the function of HDL in transporting bad cholesterol also causes blood vessels to dilate due to increased NO production. Objective: To find out the relationship between systolic blood pressure and HDL cholesterol levels in type 2 diabetes mellitus patients at the Arafah Clinic, Central Lampung, 2020. Method: This type of research used in this research is descriptive-analytic with cross-sectional design. The sampling technique was total sampling. Respondents in this study were patients with Type 2 Diabetes Mellitus at the Arafah Clinic in Central Lampung in 2020 Results: Based on the results of the chi-square statistical test, it was found that there was no relationship with the results of p = 0.898 (p> 0.05). Conclusion: There is no correlation between systolic blood pressure and HDL cholesterol levels in type 2 diabetes mellitus patients at the Arafah Clinic, Central Lampung in 2020. Keywords: Diabetes Mellitus type 2, Systolic Blood Pressure, HDL   INTISARI: HUBUNGAN TEKANAN DARAH SISTOLIK DENGAN KADAR KOLESTEROL HDL PADA PASIEN DIABETES MELLITUS TIPE 2 DI KLINIK ARAFAH LAMPUNG TENGAH Latar Belakang: Hipertensi merupakan faktor risiko utama untuk terjadinya Diabetes Melitus tipe 2, hipertensi dapat membuat sel tidak sensitif terhadap insulin, maka kadar gula di dalam darah juga dapat mengalami gangguan. Dislipidimia menyebabkan terjadinya penyempitan dalam pembuluh darah atau aterosklerosis yang dapat memperberat kondisi hipertensi ataupun diabetes mellitus. Sedangkan fungsi HDL mengangkut kolesterol jahat juga menyebabkan pembuluh darah bisa berdilatasi karena produksi NO yang meningkat.Tujuan: Untuk mengetahui Hubungan Antara Tekanan Darah Sistolik dengan Kadar HDL Kolesterol pada pasien Diabetes Melitus tipe 2 di Klinik Arafah Lampung Tengah Tahun 2020.Metode: Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif analitik dengan desain cross sectional. Teknik pengambilan sampel berupa total sampling. Responden dalam penelitian ini adalah pasien Diabetes Melitus tipe 2 di Klinik Arafah Lampung Tengah.Hasil: Berdasarkan hasil uji statistic chi-square didapatkan tidak terdapat hubungan dengan hasil p=0,898 (p>0,05).Kesimpulan: Tidak terdapat Hubungan Antara Tekanan Darah Sistolik dengan Kadar HDL Kolesterol pada pasien Diabetes Melitus tipe 2 di Klinik Arafah Lampung Tengah tahun 2020. Kata Kunci     : Diabetes Melitus tipe 2, Tekanan Darah Sistolik, HDL

scholarly journals Hubungan Antara Tekanan Darah Sistolik dengan Kadar Kolesterol Total pada Pasien Diabetes Melitus Tipe 2 di Klinik Arafah Lampung Tengah

2021 ◽  
Vol 3 (4) ◽  
pp. 562-569
Author(s):  
Firhat Esfandiari ◽  
Tusy Triwahyuni ◽  
Resti Arania ◽  
Najmi Bias Aysa
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Cross Sectional ◽  
Cholesterol Levels ◽  
Diabetes Melitus

ABSTRACT: RELATIONSHIP BETWEEN SYSTOLIC BLOOD PRESSURE AND TOTAL CHOLESTEROL LEVEL IN TYPE 2 DIABETES MELLITUS PATIENTS IN ARAFAH CLINIC, CENTRAL LAMPUNG Background: Diabetes mellitus type 2 is a disease characterized by hyperglycemia, with the underlying cause being an increase in insulin resistance and or an increase in pancreatic beta cell dysfunction (Decroli, 2019). Diabetes mellitus, hypertension and increased cholesterol levels are conditions that are often found to be interrelated. Hypertension and increased cholesterol levels can be comorbid conditions that accompany DM (Noviyanti et al., 2015). Objective: This study aimed to determine the correlation between systolic blood pressure levels and total cholesterol levels in patients with type 2 diabetes mellitus at the Arafah Clinic, Central Lampung. Method: The type of research used in this research is descriptive analytic with aapproach Cross Sectional. As well as samples taken from Arafah Clinic patients diagnosed with type 2 diabetes, as many as 46 patients. Results: Based on the results of thetest, it was fisher exact found that there was no correlation with the p value = 0.735 (p> 0.05). Conclusion: H0 is received, which means there is no significant correlation between systolic blood pressure and total cholesterol levels in type 2 DM patients at the Arafah Clinic, Central Lampung. Keywords: Systolic Blood Pressure, Total Cholesterol Levels, Type 2 Diabetes Mellitus  INTISARI: HUBUNGAN ANTARA TEKANAN DARAH SISTOLIK DENGAN KADAR KOLESTEROL TOTAL PADA PASIEN DIABETES MELITUS TIPE 2 DI KLINIK ARAFAH LAMPUNG TENGAH Latar Belakang: Diabetes Melitus tipe 2 merupakan suatu penyakit dengan karakteristik hiperglikemia, dengan penyebab yang mendasarinya adalah peningkatan resistensi insulin dan atau peningkatan disfungsi sel beta pankreas (Decroli, 2019). Diabetes melitus, hipertensi dan peningkatan kadar kolesterol merupakan keadaan yang sering dijumpai saling berkaitan. Hipertensi dan peningkatan kadar kolesterol bisa menjadi kondisi komorbiditas yang menyertai DM (Noviyanti et al., 2015).Tujuan: Penelitian ini ditujukkan untuk mengetahui hubungn antara kadar tekanan darah sistolik dengan kadar kolesterol total pada pasien diabetes melitus tipe 2 di Klinik Arafah Lampung Tengah.Metodologi: Jenis penelitian yang digunakan pada penelitian ini adalah deskriptif analitik dengan pendekatan Cross Sectional. Serta sampel diambil dari pasien Klinik Arafah yang terdiagnosa DM tipe 2 yaitu sebanyak 46 pasien.Hasil: Berdasarkan dari hasil uji fisher exact didapatkan tidak adanya hubungan dengan nilai p =0,735 (p>0,05).Kesimpulan: Didapatkan H0 yang diterima yang berarti tidak ada hubungan yang signifikan antara tekanan darah sistolik dengan kadar koletesterol total pada pasien DM tipe 2 di Klinik Arafah Lampung Tengah. Kata Kunci:Tekanan Darah Sistolik, Kadar Kolesterol Total, Diabetes Melitus tipe  

scholarly journals Prediction of type 2 diabetes mellitus using fasting plasma glucose and HbA1c levels among individuals with impaired fasting plasma glucose: a cross-sectional study in Thailand

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e041269
Author(s):  
Tullaya Sitasuwan ◽  
Raweewan Lertwattanarak
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Fasting Plasma

ObjectivesAbout 11%–30% of individuals with impaired fasting plasma glucose (IFG) have type 2 diabetes mellitus (T2DM), diagnosed by the 75 g oral glucose tolerance test (75 g OGTT). This study investigated (1) the prevalence and cut-off levels for fasting plasma glucose (FPG) and glycated haemoglobin A1c (HbA1c) in IFG individuals that most effectively predict the presence of T2DM diagnosed by a 75 g OGTT; (2) the predictors associated with T2DM; and (3) the pathophysiological characteristics of patients with IFG.Materials and methodsA single-centre, cross-sectional study was conducted in a primary care setting. A standard 75 g OGTT was performed on 123 subjects with IFG. Their beta-cell function and insulin resistance were calculated through plasma glucose and insulin levels monitored during the 75 g OGTT.ResultsIn the IFG subjects, the prevalence of T2DM using the 2-hour postload plasma glucose (2hPG) criterion was 28.5%. Pre-diabetes and normal glucose metabolism were found in 48.7% and 22.8%, respectively, by 75 g OGTT. An HbA1c level ≥6.0% or FPG ≥5.9 mmol/L were the optimal cut-off thresholds for the prediction of the presence of T2DM. HbA1c had a sensitivity of 76.7% and specificity of 55.7% (95% CI 57.7% to 90.1% and 95% CI 43.3% to 67.6%, respectively), while FPG had a sensitivity of 85.7% and specificity of 23.9% (95% CI 69.7% to 95.2% and 95% CI 15.4% to 34.1%, respectively). The presence of metabolic syndrome, a higher HbA1c and higher FPG levels were associated with the risk of T2DM in the Thai IFG population.ConclusionsAlmost one-third of the people with IFG had T2DM diagnosed by the 2hPG criterion. HbA1c was more effective than FPG in predicting the presence of T2DM in the IFG subjects. IFG individuals with HbA1c≥6.0% or FPG≥5.9 mmol/L should be advised to undergo a 75 g OGTT to detect T2DM earlier than otherwise.

scholarly journals Association of serum creatinine levels and risk of type 2 diabetes mellitus in Korea: a case control study

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Do Kyeong Song ◽  
Young Sun Hong ◽  
Yeon-Ah Sung ◽  
Hyejin Lee
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Skeletal Muscle ◽  
Type 2 Diabetes Mellitus ◽  
Serum Creatinine ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Increased Risk

Abstract Background Reduced skeletal muscle has been suggested as a potential risk factor for type 2 diabetes mellitus (T2DM). Serum creatinine is the primary metabolite of creatine in skeletal muscle. Therefore, low serum creatinine levels may be associated with an increased risk of T2DM. We aimed to evaluate the association between serum creatinine levels and the risk of T2DM in Korea. Methods We analyzed a total of 264,832 nondiabetic adults older than 40 years of age who had undergone a national health examination at least once from 2009 to 2015 in the Korean National Health Insurance Service Cohort. Hazard ratios for T2DM were calculated. Results In men, serum creatinine levels and the risk for T2DM showed an inverse J-shaped association. This association was confirmed after adjustment for age, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), and fasting plasma glucose. In women, there was a trend that serum creatinine levels were inversely associated with the risk of T2DM among those with serum creatinine below 1.1 mg/dl. However, serum creatinine levels were not significantly associated with the risk of T2DM after adjustment for age, BMI, SBP, DBP, and fasting plasma glucose. Conclusions Reduced levels of serum creatinine were significantly associated with an increased risk of T2DM in men with creatinine below 1.20 mg/dl. There was a trend that decreased levels of serum creatinine were associated with an increased risk of T2DM among women with serum creatinine below 1.1 mg/dl, although this result was not statistically significant.

scholarly journals Determinants of Diabetes Self Care in Patients With Type 2 Diabetes Mellitus in Banyumas Regency

2018 ◽  
Vol 13 (2) ◽  
pp. 71 ◽  
Author(s):  
Eva Rahayu ◽  
Ridlwan Kamaluddin ◽  
Eti Dwi Hapsari
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family Support ◽  
Self Care ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
Knowledge Variable ◽  
Diabetes Melitus

<p align="center"><strong>DETERMINANTS OF DIABETES SELF-CARE ON PATIENTS WITH TYPE 2 DIABETES MELLITUS IN BANYUMAS REGENCY</strong></p><p align="center"><strong>Eva Rahayu, </strong><strong>Ridlwan Kamaluddin</strong><strong>, Eti Dwi Hapsari</strong></p><p align="center">Lecturer of Nursing Department, Jenderal Soedirman University</p><p align="center">“[email protected]”</p><p align="center"> </p><p align="center"><strong>ABSTRAK</strong></p><p>Penderita diabetes tipe 2 perlu menerapkan perawatan mandiri diabetes dalam rangka meminimalisir berbagai komplikasi dan penurunan kualitas hidup. Beberapa faktor diduga memiliki pengaruh terhadap penerapan  perawatan mandiri<em> </em>diabetes oleh penderita diabetestipe 2 di Kabupaten Banyumas. Tujuan penelitian ini adalah untuk  mengetahui faktor determinan yang berhubungan dengan penerapan perawatan mandiri<em>  </em>diabetes tipe 2 di Wilayah Kabupaten Banyumas. Penelitian ini menggunakan desain <em>cross sectional</em>. Populasi adalah seluruh penderita diabetes melitus tipe 2 se-Kabupaten Banyumas. Metode penarikan sample dengan teknik <em>cluster sampling</em>  dengan besar sampel 532 orang yang tersebar di 22 puskesmas se-Kabupaten Banyumas. Analisis data menggunakan uji korelasi Spearman dan Regresi Linier Ganda. Hasil penelitian menunjukkan nilai p pada masing–masing variabel yang dihubungkan dengan <em>perawatan mandiri</em> diabetes antara lain adalah jenis kelamin (p=0,043),usia (p=0,18), lama menderita diabetes (p= 0,11)  pengetahuan (p=0,000), motivasi (=0,01), serta dukungan keluarga (p=  0,000). Sebesar 10,4 % variasi perawatan mandiri diabetes  dapat dijelaskan oleh variabel pengetahuan dengan koefisien β = 0,32.  Kesimpulan penelitian adalah ada hubungan antara jenis kelamin, pengetahuan, motivasi dan dukungan keluarga dengan perawatan mandiri diabetes. Variabel pengetahuan menjadi faktor yang paling dominan berhubungan dengan perawatan mandiri diabetes<em>.</em></p><p><strong>Kata kunci : </strong>determinan, diabetes melitus<em>, </em>perawatan mandiri<em> </em>diabetes</p><p align="center"><strong> </strong></p><p align="center"><strong> </strong></p><p align="center"><strong> </strong></p><p align="center"><strong>ABSTRACT</strong></p><p align="center"><strong> </strong></p><p>Patients with type 2 diabetes need to apply self-care in order to minimize various complications and decreasing quality of life. Several factors are assumed to have an effect on the application of diabetes self-care by patients with type 2 diabetes in Banyumas Regency.  The purpose of this research was to determine the determinants related to the application of diabetes self care by patients withtype 2 diabetesin Banyumas Regency. This research used cross sectional design. Population was all patients with type 2 diabetes mellitus in Banyumas Regency. Sampling method was performed by cluster sampling technique with sample size of 532 patients spreading in 22 community health centers (Puskesmas) in Banyumas Regency. Data analysis used Spearman correlation test and Multiple Linear Regression. The result indicated that p value in each variable affecting diabetes self-care was gender  (p=0,043), age (p=0.18), duration of diabetes (p= 0.11) , knowledge (p=0.000), motivation (=0.01), and family support (p=  0.000). 10.4 % variation in diabetes self-care can be explained by knowledge variable with the coefficient β = 0.32.  It can be concluded that there was a relationship among gender, knowledge, motivation and family support on diabetes self-care. Knowledge variable was the most dominant factor related to diabetes self-care.</p><p><strong> </strong></p><br clear="ALL" /><p><strong>Keywords</strong><strong> : </strong>determinants, diabetes mellitus, diabetes self-care</p>

scholarly journals HUBUNGAN MOTIVASI DENGAN EFIKASI DIRI PADA PASIEN DENGAN DIABETES MELITUS TIPE II DI RUMAH SAKIT UMUM GMIM PANCARAN KASIH MANADO

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Mario E. Katuuk ◽  
Vandri D. Kallo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Self Efficacy ◽  
Fisher Exact Test ◽  
Cross Sectional ◽  
Exact Test ◽  
The Relationship ◽  
Diabetes Melitus

Abstract: Motivation of each individual is related to the self-efficacy that each individual has. The low level of client motivation affects client's self-efficacy, so that self-care management of DM patients cannot run well. The purpose of this study is to know the relationship between motivation and self-efficacy in patients with type 2 diabetes mellitus at the GMIM Hospital Pancaran Kasih Manado in 2018. The Design of this study was descriptive analytical with cross sectional approach. The study was conducted at the GMIM Hospital Pancaran Kasih Manado. The sample used was 34 patients. The instruments used were questionnaire demographic characteristics of respondents, motivational questionnaires, and self-efficacy questionnaires tested using the Fisher Exact test. The results of the Fisher Exact statistic test are the relationship between motivation and self-efficacy of patients with Type 2 Diabetes Mellitus at GMIM General Hospital Pancaran Kasih Manado obtained p = 0.026 (α = 0.05). The conclusion is that there is a relationship between motivation and self-efficacy of patients with Type 2 Diabetes Mellitus in RSU GMIM Pancaran Kasih Manado. Keywords: Motivation, Self-Efficacy.Abstrak: Motivasi dari setiap individu berkaitan dengan efikasi diri yang dimiliki oleh masing-masing individu tersebut. Tingkat motivasi klien yang rendah mempengaruhi efikasi diri klien, sehingga manajemen perawatan diri pasien DM tidak dapat berjalan dengan baik. Tujuan dalam penelitian ini ialah diketahui hubungan antara motivasi dengan efikasi diri pada pasien diabetes melitus tipe 2 di RSU GMIM Pancaran Kasih Manado tahun 2018.. Jenis penelitian yang digunakan adalah deskriptif analitik dengan pendekatan cross sectional. Penelitian dilaksanakan di RSU GMIM Pancaran Kasih Manado.. Sampel yang digunakan sebanyak 34 pasien. Instrumen yang digunakan kuesioner karakteristik demografi responden, kuesioner motivasi, dan kuesioner efikasi diri yang diuji menggunakan uji Fisher Exact. Hasil uji statistik Fisher Exact hubungan antara motivasi dengan efikasi diri pasien Diabetes Melitus Tipe 2 di Rumah Sakit Umum GMIM Pancaran Kasih Manado diperoleh nilai p = 0,026 (α = 0,05). Kesimpulan yaitu ada hubungan antara motivasi dengan efikasi diri pasien Diabetes Melitus Tipe 2 di RSU GMIM Pancaran Kasih Manado.Kata Kunci: Motivasi, Efikasi Diri

scholarly journals Glucometers for Patients with Type 2 Diabetes Mellitus: Are they helpful?

2021 ◽  
Vol 9 (2) ◽  
pp. 140-144
Author(s):  
Andrew Thomas ◽  
Mohan T. Shenoy ◽  
K.T. Shenoy ◽  
Nirmal George
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Plasma Glucose ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Glucose Levels ◽  
The Mean ◽  
Glycated Hemoglobin Level

Background: The effectiveness of self-monitoring of blood glucose (SMBG) in type 2 diabetes mellitus (T2DM) patients is debated in the literature. We aimed at elucidating the association and patterns of complications between SMBG use and plasma glucose values. Methods: This cross-sectional study comprised 303 participants from outpatient departments with T2DM for over 12 months. We analyzed sociodemographic and clinical variables including: anthropometry, SMBG use, disease duration, treatment modality, complications, plasma glucose level, and glycated hemoglobin level (%). Results: The mean duration of T2DM was 93±76 months. Participants were grouped into SMBG users (n=115, 38%) and non-SMBG users (n=188, 62%). The mean fasting plasma glucose levels of SMBG and non-SMBG users were 140.7±42.7 (95% Confidence Interval [95%CI]: 132.72;148.67) mg/dl and 145.4±50 (95%CI: 138.12;152.67) mg/dl (p=0.03), respectively. The mean post-prandial plasma glucose levels of the SMBG and non-SMBG groups were 202±63.42 (95%CI: 190.23;213.76) mg/dl and 209±84.54 (95%CI: 196.56;221.43) mg/dl (p=0.002), respectively. The mean difference in HbA1c among the groups were 8.14±1.69% (95%CI: 7.59;8.68) and 8.15±1.98% (95%CI: 7.27;9.02) (p=0.4), respectively. Hypoglycemia (n=50, 43.5%) was the most common complication. The prevalence of neuropathy (n=5, 4.3%, p=0.036) and cardiovascular disease (n=21, 18.3%, p=0.042) were significantly higher in the SMBG group. Conclusion: Although plasma glucose values were significantly lower in the SMBG group, its clinical significance remains questionable. Furthermore, many participants in both the groups had shortfalls in awareness, monitoring, and glycemic control. SMBG use needs to be evaluated in a cohort of patients with T2DM with adequate health awareness.

scholarly journals Drug Use Evaluation on Type 2 Diabetes Mellitus and Diabetic Nephropathy Inpatients in One of Hospitals in Tasikmalaya

2018 ◽  
Vol 7 (4) ◽  
pp. 243
Author(s):  
Najiah R. Nisa ◽  
Muharram Priatna ◽  
Yedy P. Sukmawan
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Filtration Rate ◽  
Drug Selection ◽  
Cross Sectional ◽  
Drugs Interaction ◽  
Diabetes Melitus

Type 2 Diabetes mellitus (T2DM) is a degenerative disease and approximately 50% of patients with diabetes mellitus (DM) of more than 20 years’ duration also have diabetic nephropathy (DN). T2DM accounts for significant morbidity and mortality, however appropriate treatment can reduce the events. The objective of the study was to evaluate of drug use in inpatient T2DM and DN. This was a cross-sectional study with concurrent data retrieval on T2DM and DN inpatients in the period of March–June 2017 in one of hospitals in Taskimalaya, Indonesia. Forty-six patients were included in the study, of which 25 patients had T2DM and 21 had DN. The result of this study showed that appropriateness of drug selection reached 100% and 85.6% in T2DM and DN inpatients, respectively. Inappropriateness of drugs selection includes selection of ketorolac, ranitidine, folic acid, amlodipine and potassium containing drugs. Doses accuracy of T2DM patients reached 100% and of DN inpatients reached 92.1%. The inaccuracy of doses was due to the lack of dose adjustment to estimated glomerulus filtration rate (eGFR) level in each patient. Drugs interaction analysis showed a potential drug interaction on DN and T2DM which devided into major (13.8%; 7.2%), moderate (64.1%; 58%) and minor (22,1%; 34.8%). Based on the result, it is found an inappropriate drug selection and an inaccuracy of dose in DN patients, and a high percentage of drugs interaction on moderate classification in both diseases. It is necessary to optimize the role of pharmacist as a part of the healthcare team in the patient’s room to apply medication therapy management.Keywords: Drugs use evaluation, type 2 diabetes mellitus, diabetic nephropathyEvaluasi Penggunaan Obat pada Pasien Rawat Inap Diabetes Melitus Tipe 2 dan Nefropati Diabetik di Salah Satu Rumah Sakit di TasikmalayaAbstrakDiabetes melitus tipe 2 (DMT2) merupakan penyakit degeneratif dan sekitar 50% dari pasien yang telah menderita penyakit diabetes melitus (DM) selama lebih dari 20 tahun juga menderita penyakit nefropati diabetik (ND). Penyakit DMT2 dan nefropati diabetik mengakibatkan tingginya angka morbiditas dan mortalitas. Akan tetapi, penatalaksanaan terapi yang tepat dapat menurunkan kejadian tersebut. Tujuan penelitian ini adalah untuk melakukan evaluasi penggunaan obat pada pasien rawat inap dengan penyakit DMT2 dan ND. Penelitian ini menggunakan metode cross-sectional dengan pengambilan data secara konkuren terhadap pasien rawat inap DMT2 dan ND pada periode Maret–Juni tahun 2017 di salah satu rumah sakit di Tasikmalaya, Indonesia. Empat puluh enam pasien diikutsertakan, dengan 25 pasien menderita penyakit DMT2 dan 21 pasien menderita ND. Dari hasil penelitian ini, diperoleh ketepatan penggunaan obat pada penderita DMT2 mencapai 100% sedangkan pada penderita ND mencapai 85,6%. Ketidaktepatan pemilihan obat meliputi pemilihan ketorolac, ranitidine, asam folat, amlodipine dan kalium klorida. Ketepatan dosis pada penderita DMT2 mencapai 100%, sedangkan pada penderita ND mencapai 92,1%. Ketidaktepatan dosis disebabkan oleh tidak adanya penyesuaian dosis dengan nilai estimated glomerulus filtration rate (eGFR) terhadap pasien. Selain itu, ditemukan potensi interaksi obat pada penderita ND dan DMT2 yang diklasifikasikan ke dalam kategori mayor (13,8%; 7,2%), moderat (64,1%; 58%), dan minor (22,1%; 34,8%), secara berturut-turut. Berdasarkan hasil penelitian, ditemukan ketidaktepatan pemilihan obat dan ketidaktepatan dosis pada pasien ND serta tingginya persentase potensi interaksi obat, terutama kategori moderat, pada kedua penyakit. Diperlukan optimalisasi peran apoteker sebagai bagian dari tim di ruangan pasien rawat inap untuk melakukan penerapan pemantauan terapi obat.Kata kunci: Diabetes melitus tipe 2, evaluasi penggunaan obat, nefropati diabetik

Sign in / Sign up

Export Citation Format

Share Document