The Effects of Saturated and Unsaturated Fat Intake on the Skeletal Muscle’s LPL mRNA Expression in Rats

2021 ◽  
Vol 6 (4) ◽  
pp. 33-44
Author(s):  
Wookwang Cheon ◽  
Jusik Park
Keyword(s):  
Mrna Expression ◽  
Fat Intake ◽  
Unsaturated Fat

scholarly journals Associations of Monounsaturated Fats to Visual Cognitive Performance Training in Older Adults

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 920-920
Author(s):  
Aaron Riviere ◽  
Nicos Georghiades ◽  
Karen Beathard ◽  
Steven Riechman
Keyword(s):  
Cognitive Performance ◽  
Saturated Fat ◽  
Health Study ◽  
Fat Intake ◽  
Monounsaturated Fat ◽  
Dynamic Complexity ◽  
Unsaturated Fat ◽  
Monounsaturated Fats ◽  
Total Fat ◽  
Visual Cognitive

Abstract Objectives High levels of visual cognitive performance (VCP) are required for complex daily activities including driving and participating in sports. Many cognitive tests use simple measures of social cognition or memory that lack the dynamic complexity needed for daily living. Healthy fats including mono- and polyunsaturated fats have been shown to improve cognition and brain health due to the need for fatty acids for neurotransmitter production and myelin sheath insulation. The effects of specific fats on specific cognitive functions is still poorly understood. The Nutrition, Vision, and Cognition in Health Study (IONHealth) investigates nutritional and behavioral factors that influence cognition in 3-dimensional multiple objects tracking test (3DMOT). It was hypothesized that monounsaturated fats would affect cognitive performance. Methods 104 men and women adults age 50–75 years recorded 15 food logs and completed 15 training sessions (Neurotracker) during 10 lab visits over 15 days. Food logs were used to represent typical eating patterns for each individual and means over 15 days were used for analyses. Results Monounsaturated fat intake was significantly associated to VCP, however, this affect was not distinct from overall fat intake where higher fat intake (114.7, 99.8, 71.8, 62.9 g/day mean) was significantly associated (P < 0.01) to higher VCP (1.10, 1.04, 0.89, 0.79 speed threshold mean, respectively). Conclusions Increased total fat intake may have a positive effect on brain function, even with higher saturated fat and lower unsaturated fat intake. Funding Sources Egg Nutrition Council.

scholarly journals Reproducibility of a food frequency questionnaire for adolescents

2007 ◽  
Vol 23 (9) ◽  
pp. 2187-2196 ◽  
Author(s):  
Dirce Maria Lobo Marchioni ◽  
Silvia Maria Voci ◽  
Flávia Emília Leite de Lima ◽  
Regina Mara Fisberg ◽  
Betzabeth Slater
Keyword(s):  
Vitamin C ◽  
Food Frequency Questionnaire ◽  
Extreme Values ◽  
Intraclass Correlation ◽  
Weighted Kappa ◽  
Fat Intake ◽  
Food Frequency ◽  
Unsaturated Fat ◽  
Total Fat ◽  
The City

To assess the reproducibility of a validated 76-item food frequency questionnaire designed to estimate diet in adolescents (Adolescent Food Frequency Questionnaire - AFFQ) in the city of Sao Paulo, Brazil, a test-retest study was conducted (n = 49). Intraclass correlation coefficient (ICC), weighted kappa, and percentage of agreement were used in both crude and energy-adjusted nutrient intakes. Bland Altman plots were used to examine the limits of agreement for energy and macronutrients. The ICC ranged from 0.48 (carbohydrates) to 0.65 (vitamin C) in crude values and from 0.25 (total fat) to 0.58 (vitamin C) in adjusted values. Kappa values ranged from 0.28 (protein and fiber) to 0.56 (unsaturated fat). Bland Altman showed a trend towards larger difference in energy according to increased intake values and a bias towards extreme values for fat intake. The percent of individuals classified in the same category on the two occasions was on average 54.2%. By conclusion, the Adolescent Food Frequency Questionnaire showed reasonable reproducibility and can be used in studies that aim to classify groups into intake categories.

scholarly journals Trans Fatty Acid Intake Modulates the Expression of Uncoupling Proteins 2 and 3 (UCP2 & UCP3) mRNA in Children

2021 ◽  
Vol 9 (1) ◽  
pp. 139-146
Author(s):  
Walaa M Sarhan ◽  
Safaa El-Hussien Tawfik ◽  
Amal S El-Shal ◽  
Vishruti Makani ◽  
Hanim M. Abdel-Nour
Keyword(s):  
Mrna Expression ◽  
Uncoupling Proteins ◽  
Fat Intake ◽  
Trans Fat ◽  
Trans Fats ◽  
Trans Fatty Acid Intake ◽  
Ucp2 Expression ◽  
Increased Risk ◽  
Induced Changes ◽  
Ucp3 Expression

Increased consumption of Trans Fats is associated with increased risk of Coronary Heart Disease. Uncoupling proteins (UCPs) are mitochondrial proteins that disperse the inter-membrane electrochemical potential as heat. We aimed to detect the relation of high Trans-fat intake in diet on the expression of UCP2&3 m-RNA in children. A specific questionnaire to parents of sixty-eight children (4-15 years) was conducted. Accordingly, the subjects were sub-grouped into; High Trans-fat consuming group (37 subjects) and a Medium Trans-fat consuming one (31 subjects). Samples collected from Peripheral blood to analyze UCP2&3 mRNA expression by Real Time Polymerase Chain Reaction (RT-PCR). Levels of UCP2 expression was reduced in children consuming High Trans-fat (2.5 ±0.7) in comparison with Medium Trans-fat consuming ones (1.5± 0.2) with (p<0.001). However, not much significance was showed in UCP3 expression with values (2.1±0.5) in the High consuming group and (1.9±0.2) in Medium consuming group with (p=0.08). In Delta relationship the diet-induced changes in UCP2 (r=0.66, P=0.002) and UCP3 (r=0.61, P=0.06) mRNA expression was negatively correlated with percentage of Trans-fat in diet. The correlation of UCP2&3 mRNA expression and high Trans-fat intake suggests a mechanism by which high Trans-fat diet plays a role in childhood obesity.

Oxidative stress and mrna expression after an oral unsaturated fat load test in subjects with abdominal obesity

2014 ◽  
Vol 235 (2) ◽  
pp. e169
Author(s):  
S. Martinez-Hervas ◽  
I. Navarro ◽  
A.B. Garcia-Garcia ◽  
E. Nuñez Savall ◽  
E. Benito ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mrna Expression ◽  
Abdominal Obesity ◽  
Load Test ◽  
Unsaturated Fat

Cardiovascular event risk in relation to dietary fat intake in middle-aged individuals: data from The Malmö Diet and Cancer Study

2007 ◽  
Vol 14 (5) ◽  
pp. 701-706 ◽  
Author(s):  
Margret Leosdottir ◽  
Peter M. Nilsson ◽  
Jan-Åke Nilsson ◽  
Göran Berglund
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Event ◽  
Cardiovascular Events ◽  
Saturated Fat ◽  
Fat Intake ◽  
Cancer Study ◽  
Unsaturated Fat ◽  
Event Risk ◽  
Diet And Cancer ◽  
Total Fat

Background and design The hypothesis that diets rich in total and saturated fat and poor in unsaturated fats increase the risk for cardiovascular disease is still vividly debated. The aim of this study was to examine whether total fat, saturated fat, or unsaturated fat intakes are independent risk factors for cardiovascular events in a large population-based cohort. Methods 28098 middle-aged individuals (61% women) participated in the Malmö Diet and Cancer Study between 1991 and 1996. In this analysis, individuals with an earlier history of cardiovascular disease were excluded. With adjustments made for confounding by age and various anthropometric, social, dietary, and life-style factors, hazard ratios (HR) were estimated for individuals categorized by quartiles of fat intake [HR (95% confidence interval, CI), Cox's regression model]. Results No trend towards higher cardiovascular event risk for women or men with higher total or saturated fat intakes, was observed. Total fat: HR (95% CI) for fourth quartile was 0.98 (0.77-1.25) for women, 1.02 (0.84-1.23) for men; saturated fat: 0.98 (0.71-1.33) for women and 1.05 (0.83-1.34) for men. Inverse associations between unsaturated fat intake and cardiovascular event risk were not observed. Conclusions In relation to risks of cardiovascular events, our results do not suggest any benefit from a limited total or saturated fat intake, nor from relatively high intake of unsaturated fat. Eur J Cardiovasc Prev Rehabil14:701-706 © 2007 The European Society of Cardiology

DIETARY FAT INTAKE AND COGNITIVE FUNCTION AMONG OLDER POPULATIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS

2019 ◽  
pp. 1-8
Author(s):  
G.-Y. Cao ◽  
M. Li ◽  
L. Han ◽  
F. Tayie ◽  
S.-S. Yao ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Dietary Fat ◽  
Saturated Fat ◽  
Cognitive Outcomes ◽  
Fat Intake ◽  
Unsaturated Fat ◽  
Dietary Fat Intake ◽  
Fat Consumption ◽  
Saturated Fat Intake

Objective: The associations between dietary fat intake and cognitive function are inconsistent and inconclusive. This study aimed to provide a quantitative synthesis of prospective cohort studies on the relationship between dietary fat intake and cognitive function among older adults. Methods: PubMed, EMBASE, PsycINFO and Web of Science databases were searched for prospective cohort studies published in English before March 2018 reporting cognitive outcomes in relation to dietary fat intake. Four binary incident outcomes included were mild cognitive impairment (MCI), dementia, Alzheimer disease (AD) and cognitive impairment. The categories of dietary fat intake were based on fat consumption or the percentage of energy from fat consumption, including dichotomies, tertiles, quartiles and quintiles. The relative risk (RR) with the corresponding 95% confidence intervals (CIs) was pooled using a random effects model. Results: Nine studies covering a total of 23,402 participants were included. Compared with the lowest category of consumption, the highest category of saturated fat intake was associated with an increased risk of cognitive impairment (RR = 1.40; 95% CI: 1.02-1.91) and AD (RR: 1.87, 95% CI: 1.09-3.20). The total and unsaturated fat intake was not statistically associated with cognitive outcomes with significant between-study heterogeneity. Conclusion: This study reported a detrimental association between saturated fat intake and cognitive impairment and mixed results between unsaturated fat intake and selected cognitive outcomes. Given the substantial heterogeneity in the sample size and methodology used across studies, the evidence presented here should be interpreted with caution.

Sign in / Sign up

Export Citation Format

Share Document