scholarly journals Microbiological Evaluation of Octenidine Dihydrochloride Mouth Rinse after 5 Days' Use in Orthodontic Patients

2009 ◽  
Vol 79 (4) ◽  
pp. 766-772 ◽  
Author(s):  
Alev Aksoy Dogan ◽  
Emel Sesli Cetin ◽  
Emad Hüssein ◽  
Ali Kudret Adiloglu

Abstract Objective: To determine the absolute and relative antibacterial activity of octenidine dihydrochloride (OCT) against total and cariogenic bacteria in saliva samples of patients with fixed orthodontic appliances during 5 days of usage. Materials and Methods: The study group consisted of 5 male and 13 female subjects who were selected from patients in the Clinic of Orthodontics. Each patient was given physiologic saline (PS), chlorhexidine gluconate (CHX), polyvinylpyrrolidone-iodine complex (PVP-I), and OCT every morning for 5 days, each separated by a 2-week interval. Total and cariogenic bacteria in saliva samples of orthodontically treated patients with fixed appliances were collected during 5 days of usage. Unstimulated saliva was collected as a baseline sample. Saliva samples were collected at 15 minutes, and on the second, third, and fifth day after rinsing the mouth with any of the solutions for 30 seconds, and bacterial counts were detected. Results: OCT showed an ultimate reduction of total viable oral bacteria, Lactobacillus species, and Streptococcus mutans in vivo. OCT also had a significantly greater inhibitory effect than 0.2% CHX and 7.5% PVP-I, from the beginning of the study until the fifth day after the orthodontic appliances were bonded (P < .1). Conclusions: OCT compared favorably with respect to CHX and PVP-I complex in orthodontically treated patients with fixed appliances (P ≤ .1).

2007 ◽  
Vol 77 (5) ◽  
pp. 881-884 ◽  
Author(s):  
Emel Sari ◽  
Ilhan Birinci

Abstract Objective: To assess the effectiveness of 0.2% chlorhexidine gluconate mouth rinse on Streptococcus mutans and lactobacilli in orthodontic patients with fixed appliances. Materials and Methods: Twenty patients, aged 13–18, with fixed orthodontic appliances participated in the study. The levels of S mutans and lactobacilli in saliva samples were evaluated at four stages: at the beginning of the orthodontic treatment, at least 2 weeks after the bonding of brackets, 1 week after the introduction of 0.2% chlorhexidine gluconate mouth rinse, and at the fourth week. The changes in S mutans and lactobacilli levels were analyzed via Wilcoxon test. Results: Increases in bacterial levels of S mutans and lactobacilli were detected after the orthodontic appliances were bonded. A significant decrease in S mutans levels was observed 1 week after the introduction of chlorhexidine mouth rinse. Conclusions: An 0.2% chlorhexidine gluconate mouth rinse decreased S mutans levels, but had no effect on lactobacilli levels.


2014 ◽  
Vol 142 (5-6) ◽  
pp. 301-305 ◽  
Author(s):  
Marija Zivkovic-Sandic ◽  
Branka Popovic ◽  
Jelena Carkic ◽  
Nadja Nikolic ◽  
Branislav Glisic

Introduction. The placement of fixed orthodontic appliances may lead to increased plaque accumulation and changes in subgingival microflora. Objective. The aim of this study was to examine the changes in frequency of subgingival microflora that occur after placement and removal of fixed orthodontic appliance using polymerase chain reaction (PCR). Methods. This study included 33 orthodontic patients, who were divided into two groups. Subgingival plaque samples were collected from the right upper incisor (U1) and right upper first molar (U6). In group A, the samples were taken three times: before placement appliance (T1), after one month (T2), and after 3 months (T3). In group B the samples were also taken three times: before appliance removal (T1), after one month (T2), and after three months (T3). PCR method was used to determine the presence of P. gingivalis, A. actinomycetemcomitans, T. forsythia, and P. intermedia. Results. In group A the frequency of P. gingivalis showed statistically significant decrease at U1 (p=0.049) and U6 (p=0.008), from T1 to T2, and at U1 (p=0.048) from T1 to T3. In group B only the frequency of T. forsythia showed a statistically significant decrease, at U6 (T1 vs. T2, p=0.004; T1 vs. T3, p=0.0003). Regarding other analyzed bacteria, changes in the presence were noticed but no statistical significance was found. Conclusion. Placement of fixed appliances may have an impact on subgingival microflora, but in the first months after the placement and removal of the appliance changes were not significant, probably due to good oral hygiene.


Author(s):  
A. G. Skubitskaya ◽  
I. V. Firsova ◽  
S. V. Poroyskyi ◽  
O. G. Strusovskaya

Relevance. The high necessity in orthodontic treatment among young patients and the use of fixed orthodontic appliances for the treatment of dental pathology are the factors that initiate inflammatory periodontal processes. Timely diagnosis and optimal preventive and treatment procedures can prevent or stop the inflammatory periodontal complications which could have developed during the orthodontic treatment. One of the effective methods for the prevention and treatment of inflammatory periodontal diseases is the use of targeted antimicrobial agents based on medicinal plants that have specific antimicrobial activity against periodontal pathogens. Purpose – to study the effectiveness of the dental gel with barberry extract for the treatment of plaque-induced gingivitis in orthodontic patients during the active phase of the treatment with fixed appliances.Materials and methods. The study included 60 patients (35 women and 25 men) aged 18 to 35 years who had presented for the orthodontic care. The patients undergoing orthodontic treatment with fixed appliances were randomly divided into two groups. In group I, the patients were prescribed applications of a dental gel with barberry extract; in group II, this medication was not prescribed. The clinical condition of the periodontium was assessed with periodontal indices PMA, SBI and OHI-S. The immune status was evaluated by the level of secretory IgA, interleukins (IL-1β and IL-4) and tumor necrosis factor-α (TNF-α). The patients were followed up during 1 month of treatment. The results were statistically processed with Statsoft Statistica 8.0 and Graph Pad Prism 5.0.Results. In group II, the production of immunoglobulin IgA, pro- and anti-inflammatory cytokines was impaired after a month of treatment, associated with a significant deterioration in the oral hygiene status and an increase in PMA (by 3 times), SBI (by 5.3 times) indices. In group II, the oral fluid concentrations of IL-1β, IL-4 and TNF-α significantly differed from those in group I as of the 7th day of the observation period and indicated suppression of the mucosal immunity. Clinical and immune parameters of the group I patients improved and were comparable with the control by the end of the observation month.Conclusions. Patients with dental abnormalities are at risk of developing inflammatory periodontal diseases. The results of the immunological tests, performed during the treatment with the use of a dental gel with barberry extract, demonstrated the recovery of the local immunity, as evidenced by the elevation of secretory immunoglobulin A in saliva and improvement of cytokine profile parameters.


2007 ◽  
Vol 77 (1) ◽  
pp. 124-128 ◽  
Author(s):  
Alev Aksoy ◽  
Nizami Duran ◽  
Serdar Toroglu ◽  
Fatih Koksal

Abstract Objective: To determine antibacterial activity of chewing mastic gum against the salivary levels of Streptococcus mutans, the total number of viable bacteria, and lactobacilli in patients undergoing therapy with fixed orthodontic appliances. Materials and Methods: In this study, the levels of S mutans, lactobacilli, and total cultivated bacteria were measured before and after chewing mastic gum. The antibacterial effects of chewing mastic gum against these microorganisms in saliva were compared with a placebo gum. The counts for orthodontically treated patients were evaluated before chewing gum; just after chewing gum; and after 45, 75, 105, and 135 minutes. Saliva samples taken from the patients were inoculated onto trypticase-yeast-cystine-bacitracin agar for mutans streptococci and onto Rogosa agar for lactobacilli. The agar plates were incubated for 48 hours anaerobically at 37°C. The total number of viable bacteria was then counted. Results: Just after chewing the mastic gum for 15 minutes, a significant decrease of total bacteria and S mutans was observed (P < .001). The reduction in lactobacilli was not significant at later first stage (P > .05). However, at the end of 135 minutes, there were significantly fewer S mutans (P < .001), total viable bacteria (P < .001), and lactobacilli (P < .001) in the oral cavity after chewing mastic gum than after chewing paraffin (P < .001). The results show that chewing mastic gum decreased the total viable bacteria, S mutans, and lactobacilli in saliva in orthodontically treated patients with fixed appliances. Conclusion: Chewing mastic gum might be useful in preventing caries lesions.


2018 ◽  
Vol 89 (3) ◽  
pp. 385-390 ◽  
Author(s):  
Christina Erbe ◽  
Collin Jacobs ◽  
Malgorzata Klukowska ◽  
Hans Timm ◽  
Julie Grender ◽  
...  

ABSTRACT Objective: To compare the plaque removal efficacy of an oscillating-rotating electric toothbrush with an orthodontic brush head versus a sonic toothbrush in adolescent patients with fixed orthodontic appliances. Materials and Methods: This was a randomized, examiner-blind, replicate single-use, two-treatment, four-period, crossover study with a washout period between visits of approximately 24 hours. Forty-four adolescent patients with fixed orthodontic appliances in both arches were randomized based on a computer-generated randomization schedule to one of four toothbrush treatment sequences. The primary outcome was plaque score change from baseline, measured using digital plaque imaging analysis. Results: Baseline plaque levels for both brush treatments were high, covering more than 50% of the tooth area. Effective plaque removal was observed with both brush treatments (P < .001); however, the reduction in plaque with the oscillating-rotating toothbrush was statistically significantly greater (P = .017) compared with the sonic toothbrush. Conclusions: The study provides evidence for more effective plaque-removing efficacy of the oscillating-rotating toothbrush versus the sonic toothbrush among orthodontic patients.


2012 ◽  
Vol 140 (1-2) ◽  
pp. 22-28 ◽  
Author(s):  
Tijana Sessa ◽  
Jelena Civovic ◽  
Tina Pajevic ◽  
Jovana Juloski ◽  
Milos Beloica ◽  
...  

Introduction. Therapy with fixed orthodontic appliances starts with bracket bonding and ends with debonding of brackets, leaving enamel surface varied. Objective. The aim of this pilot study was to examine enamel surface before and after debonding of orthodontic brackets by the use of scanning electron microscopy (SEM). Methods. Epoxy replicas of four patients? premolars indicated for therapy with fixed orthodontic appliances were made and brackets were bonded to their teeth with a different adhesives (Enlight, No-mix, Fuji Ortho LC and Heliosit Orthodontic) (n=4). Two months later, brackets on premolars were debonded and amounts of adhesive left on the tooth surfaces and the bracket bases were evaluated with the adhesive remnant index (ARI). After resin removal, epoxy replicas were made and the surface of premolars was evaluated with the enamel surface index (ESI). All replicas of premolars (n=32) were prepared for SEM examination and compared under different magnifications. Tooth damage was estimated based on correlation between ARItooth and ESI. Results. Pearson?s ?2 test showed no significant differences between ARItooth and ARIbracket of four materials used. Nonparametric correlations showed significant differences between ARItooth and ARIbracket, ESI and ARItooth, and between ESI and ARIbracket. Increasing of ARItooth is followed with the descent of ARIbracket and the ascent of ESI. Multivariate regression analysis showed a significant correlation between ESI and ARItooth. Conclusion. Most bond failures took place at enamel-adhesive interface. ARItooth was a predictor to enamel surface damage. The type of material did not affect enamel surface damage.


2018 ◽  
Vol 88 (6) ◽  
pp. 806-811 ◽  
Author(s):  
Ioannis P. Zogakis ◽  
Erez Koren ◽  
Shlomit Gorelik ◽  
Isaac Ginsburg ◽  
Miriam Shalish

ABSTRACT Objectives: To examine possible changes in the levels of salivary antioxidants, C-reactive protein (CRP), cortisol, pH, proteins, and blood in patients treated with fixed orthodontic appliances. Materials and Methods: Salivary samples from 21 orthodontic patients who met specific inclusion criteria were collected before the beginning of orthodontic treatment (T0; baseline), 1 hour after bonding (T1), and 4–6 weeks after bonding (T2). Oxidant-scavenging ability (OSA) was quantified using a luminol-dependent chemiluminescence assay. Cortisol and CRP levels were measured using immunoassay kits. pH levels and presence of proteins and blood in the samples were quantified using strip-based tests. Results: A significant decrease in salivary pH was observed after bonding (P = .013). An increase in oxidant-scavenging abilities during orthodontic treatment was detected, but the change was not statistically significant. Cortisol and CRP levels slightly increased after bonding, but the difference was small without statistical significance. Changes in the presence of proteins and blood were also insignificant. Conclusions: Exposure to fixed orthodontic appliances did not show a significant effect on salivary parameters related to inflammation or stress, with the exception of a significant but transient pH decrease after bonding.


2018 ◽  
Vol 88 (5) ◽  
pp. 530-537
Author(s):  
E. Erin Bilbo ◽  
Steven D. Marshall ◽  
Karin A. Southard ◽  
Verrasathpurush Allareddy ◽  
Nathan Holton ◽  
...  

ABSTRACT Objectives: The long-term skeletal effects of Class II treatment in growing individuals using high-pull facebow headgear and fixed edgewise appliances have not been reported. The purpose of this study was to evaluate the long-term skeletal effects of treatment using high-pull headgear followed by fixed orthodontic appliances compared to an untreated control group. Materials and Methods: Changes in anteroposterior and vertical cephalometric measurements of 42 Class II subjects (n = 21, mean age = 10.7 years) before treatment, after headgear correction to Class I molar relationship, after treatment with fixed appliances, and after long-term retention (mean 4.1 years), were compared to similar changes in a matched control group (n = 21, mean age = 10.9 years) by multivariable linear regression models. Results: Compared to control, the study group displayed significant long-term horizontal restriction of A-point (SNA = −1.925°, P < .0001; FH-NA = −3.042°, P < .0001; linear measurement A-point to Vertical Reference = −3.859 mm, P < .0001) and reduction of the ANB angle (−1.767°, P < .0001), with no effect on mandibular horizontal growth or maxillary and mandibular vertical skeletal changes. A-point horizontal restriction and forward mandibular horizontal growth accompanied the study group correction to Class I molar, and these changes were stable long term. Conclusions: One phase treatment for Class II malocclusion with high-pull headgear followed by fixed orthodontic appliances resulted in correction to Class I molar through restriction of horizontal maxillary growth with continued horizontal mandibular growth and vertical skeletal changes unaffected. The anteroposterior molar correction and skeletal effects of this treatment were stable long term.


KYAMC Journal ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 129-132
Author(s):  
Md Ali Kawsar ◽  
Mohammad Rafiqul Islam ◽  
Rifat Rezwana ◽  
Md Rubayet Alam Prodhan ◽  
Md Ahsan Habib ◽  
...  

Background: Oral hygiene maintenance becomes difficult during fixed orthodontic treatment.Objective: The aim of this study was to assess Gingival Bleeding Index among patients treated with fixed orthodontic appliances in a tertiary level hospital.Metanitil and Methody: This study was conducted on 100 patients treated with fixed orthodontic appliances for more than six months in the OPD of Orthodontics Department at Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2013 to July 2014. All the information related to oral hygiene maintenance like brushing, dental floss use, use of mout hwash during treatment in the OPD were recorded. The Gingival Bleeding Index (GBI) was calculated and recorded. Apart from this, frequency of brushing, type of tooth brush, technique of brushing and inter dental brush were also considered.Result: Over all mean value of GBI was 23.44±17.00. Mean value of GBI was 26.44 ± 15.23 among patients who brushed their teeth once a day but it was decreased gradually as the patients increased frequency of toot hbrush use per day and became 11.55±4.71 among the patients who brushed their teeth thrice a day. Mean value of GBI was 23.46±17.18 who did not use dental floss and 22.85 (12.64) who used dental floss once a day. Mean value of GBI was 25.30±17.73 who used inter dental brush irregularly but 2.75±0.35 who used it thrice a day. Mean value of GBI was25.17±17.69 who did not use mouth wash whereas it reduced to 8.00±0.00 among them who used mouth wash thrice a day.Conclusion: The Gingival Bleeding Index (GBI) is increased in patients treated with fixed orthodontic appliances.KYAMC Journal Vol. 9, No.-3, October 2018, Page 129-132


2009 ◽  
Vol 79 (6) ◽  
pp. 1149-1155 ◽  
Author(s):  
Dong-Soon Choi ◽  
Bong-Kuen Cha ◽  
Paul-Georg Jost-Brinkmann ◽  
Si-Young Lee ◽  
Beom-Seok Chang ◽  
...  

Abstract Objective: To evaluate changes that occur in the subgingival microbiota after removal of fixed orthodontic appliances using polymerase chain reaction (PCR). Materials and Methods: Thirty orthodontic patients (11 males and 19 females; aged 20 ± 7.3 yr) were included in this study. Subgingival plaque samplings were gathered from the disto-buccal gingival crevice of the left upper central incisors and the left lower central incisors, and from the mesio-buccal gingival crevice of the left upper first molars and the left lower first molars, at two different times: 2 weeks before appliance removal (T1), and 3 months after appliance removal (T2). DNA was extracted from the samples and the 16S rRNA-based PCR detection method was used to determine the prevalence of Actinobacillus actinomycetemcomitans, Tannerella forsythia, Campylobacter rectus, Eikenella corrodens, Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens, and Treponema denticola, which are considered as putative periodontopathogens. Results: The frequency of positive sites at T1 and T2 was 65% and 43.3% for C. rectus, and 53.3% and 30.8% for E. corrodens, respectively. For the other bacteria, the frequency tended to be reduced between times. Conclusion: Periodontopathogens during orthodontic treatment were significantly reduced within 3 months of appliance removal. However, how long it takes to return to the preorthodontic composition of the subgingival microbiota and whether it happens at all remain to be seen.


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