Effect of Intrapapillary Local Anesthetic on Postoperative Pain Following Dental Treatment Under General Anesthesia in Pediatric Patients

Objective: This randomized, prospective, blinded study compared pain in children following dental treatment under general anesthesia (GA) using 1 of 2 established analgesia methods. Methods: Patients age 4 to 7 years were randomly assigned to a control group (intravenous [IV] analgesics) or experimental group (IV analgesics and intrapapillary local anesthetic infiltrations) between July 2017 and February 2018. During recovery from surgery, Faces, Legs, Activity, Cry, and Consolability (FLACC) scores were recorded upon regaining consciousness and reassessed every 15 minutes until discharge. Overall pain occurrence (FLACC ≥1) and moderate/severe pain occurrence (FLACC ≥4) were analyzed using mixed effects logistic regression (N = 88). Results: The experimental group had a 17% lower overall pain occurrence than the control group (16 vs 33%; p = .02). Moderate/severe pain occurrence between the groups was not significant (9 vs 22%; p = .23). The dental treatment subjects received (number of completed stainless steel crowns, extractions, and/or pulpotomies) did not significantly affect pain occurrence. Conclusion: Local anesthesia intrapapillary infiltrations around stainless steel crowns decrease overall pain occurrence but not moderate/severe pain occurrence following dental treatment under GA in pediatric patients.

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Comparison of Canine Overlap in Pediatric Patients Requiring Stainless Steel Crown Placement Under General Anesthesia Before and After the Procedure

Frontiers in Dentistry ◽

10.18502/fid.v16i1.1113 ◽

2019 ◽

Author(s):

Sara Ghadimi ◽

Bahman Seraj ◽

Abbas Ostadalipour ◽

Elnaz Askari

Keyword(s):

Stainless Steel ◽

General Anesthesia ◽

Repeated Measures ◽

Pediatric Patients ◽

Dental Treatment ◽

Contact Point ◽

Before And After ◽

Time Required ◽

The Right ◽

Primary Canine

Objectives: Despite the increasing popularity of pediatric dental treatments under general anesthesia, information is scarce regarding occlusal changes in patients receiving stainless steel crowns (SSCs) under general anesthesia. This study sought to compare canine overlap before and after general anesthesia in children receiving SSCs. In case of a change, the possibility of returning to the preoperative state and the time required for this process were also evaluated. Materials and Methods: This interventional, before-and-after study was performed on 60 children between 2 to 7 years of age requiring dental treatment under general anesthesia. The contact point of the most prominent area of the maxillary primary canine and mandibular primary canine was marked before and immediately after general anesthesia and at one and two weeks postoperatively. The change in canine overlap was analyzed using repeated measures analysis of variance (ANOVA) and linear regression test. Results: Canine overlap significantly decreased immediately after general anesthesia (P<0.05). The mean bite opening was 0.51±0.22 mm at the site of the right canine and 0.50±0.185 mm at the site of the left canine. These values returned to their normal preoperative state after one week (P<0.05). Repeated measures ANOVA showed significant differences in this respect between the time points (P=0.002). Conclusions: The occlusion and vertical dimension of pediatric patients may change following dental treatment under general anesthesia; the magnitude of change in canine overlap may vary depending on the class of occlusion and number of SSCs placed. These changes are temporary and often resolve within a week.

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QOLP-17. GROUP MEDICAL PLAY EFFECTIVELY IMPROVES HOSPITALIZATIONADAPTABILITY OF PEDIATRIC PATIENTS WITH NEUROTUMOR

Neuro-Oncology ◽

10.1093/neuonc/noaa215.742 ◽

2020 ◽

Vol 22 (Supplement_2) ◽

pp. ii178-ii178

Author(s):

Xing Zhang ◽

Fuqiang Zhang ◽

Mingyao Lai ◽

Juan Li ◽

Yangqiong Zhang ◽

...

Keyword(s):

Social Status ◽

Pediatric Patients ◽

Picture Book ◽

Family Satisfaction ◽

Control Group ◽

Play Intervention ◽

Significant Difference ◽

The Difference ◽

Therapeutic Play ◽

Experimental Group

Abstract OBJECTIVE To explore the effect of group medical games on the hospitalization adaptability of pediatric patients with neuro tumor. METHODS pediatric patients with neuro tumor (age:6 to 13 years) who were treated in hospital from June to December 2019 and were hospitalized for 1 month to 2 months. 29 pediatric patients(mean age:9y) were selected as the control group and treated as usual; 26 pediatric patients(meanage:8y) were selected as the experimental group for group therapeutic play intervention. Interventions last Monday, Wednesday and Friday of each week, with an average duration of one hour. Group medical play include: medical picture book education, medical preview game, emotional games, social table games. Two groups completed self-made questionnaires at the time of admission and two weeks after admission, including: diet, sleep, compliance, and social status, hospital adaptation and other related issues, two groups completed a satisfaction questionnaire after two weeks of admission, recorded analysis and compared the difference of questionnaire data and satisfaction of the two groups of pediatric patients. RESULTS There was no statistical difference in age and sex between the two groups, and there was no significant difference in baseline RESULTS: The re-test results showed that the experimental group was significantly better than the control group in terms of social status, hospital adaptation, compliance and family satisfaction(p＜0.05). CONCLUSION Group medical games can effectively improve the adaptability, compliance and family satisfaction of pediatric with neuro tumor.

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Cesarean section incisional infiltration with lidocaine and Epinephrine versus Lidocaine alone in reducing postoperative pain. A randomized controlled double-blinded clinical trial

QJM ◽

10.1093/qjmed/hcab115.017 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Hazem F El-Shahawy ◽

Sherif F El-Mekkawi ◽

. Haitham F Mohmmed ◽

Hend M Afifi

Keyword(s):

Caesarean Section ◽

Cesarean Section ◽

General Anesthesia ◽

Local Anesthesia ◽

Breast Feeding ◽

Local Anesthetic ◽

Elective Caesarean Section ◽

Control Group ◽

Cesarean Section Delivery ◽

Anesthetic Effect

Abstract Background Cesarean section delivery is becoming more frequent. Childbirth is an emotion-filled event and the mother needs to bond with her newborn baby as early as possible. Any intervention that leads to improvement in pain relief is worthy of investigation Aim of the Work to assess the efficacy and safety adding ef Epinephrine to lidocaine 2% in dose-related manner 1:200.000 in prolongation of anesthetic effect of lidocaine as a local anesthetic to reduce post; caesarean section pain after general anesthesia. Patients and Methods A total number of 200 women planned for elective caesarean section at Shams University Maternity Hospital Was recruited, 2 groups were randomized with a study group included 100 women received lidocaine 2% and epinephrine in dose-related manner and a control group included 100 women received lidocaine 2% only. Results women who received lidocaine and epinephrine were more satisfied and hadsignificant more time after caesarean section free of pain in comparison to women who received lidocaine only by 120 minutes. Also. adding Of epinephrine helped in decrease in amount of analgesic consumption after caesarean section. Women who received lidocaine and epinephrine started breast feeding and mobilization earlier than women who received lidocaine only. Epinephrine prolonged the action of lidocaine as a local anesthetic, this prolongation of action of local anesthetic had a significant effect in early mobilization and breast feeding and decrease in cost of analgesics. Nobody in our candidate had a post-operative infection, past operative pyrexia, Allergic reactions tar general anesthesia or complications with local anesthesia. Conclusion Adding of epinephrine to local anesthetics (such as lidocaine 2% in dose-related manner 1:200.0000) prolonged anesthetic effect by more than double of its original anesthetic time, This prolongation on anesthetic effect of local anesthesia by epinephrine helps in eariy mobilization; early breast feeding and less hospital duration stays. No complications (local nor systemic) developed with local infiltration of post-caesarean section incision with lidocaine 2% even aficr adding epinephrine in dose-related manner 1:200.000

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Pillow positioning facilitates independent bridging for bedpan use in pelvic fractures

South African Journal of Physiotherapy ◽

10.4102/sajp.v48i3.738 ◽

1992 ◽

Vol 48 (3) ◽

pp. 41-44 ◽

Cited By ~ 1

Author(s):

Jeanette A. Fourie ◽

Eileen M.P. Lief ◽

Timothy T. Dunne

Keyword(s):

Clinical Trial ◽

Stainless Steel ◽

Pelvic Fractures ◽

Control Group ◽

Mechanical Advantage ◽

Block Randomisation ◽

Significant Difference ◽

Experimental Group ◽

Conventional Stainless Steel

The idea of giving a patient with fractures of the pelvis a mechanical advantage, by placing pillows under his/her back in order to make bridging for the bedpan easier, was tested in this clinical trial. Twenty nine subjects were entered by block randomisation into the experimental group and twenty nine into the control group. The number of days from entry into the trial until independent bridging was noted. Independent bridging is defined as the patient being able to lift high enough to slide a conventional stainless steel bedpan under the buttocks. Results show that there is a significant difference in time to bridging (Y = 0,602, p = 0,0027) in favour of the experimental group. Other variables studied appear to marginally favour the control rather than the experimental group, thus suggesting that the pillow method could be used safely and effectively in the treatment of patients who have sustained a range of pelvic fractures.

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The GlideScope with modified Magill forceps facilitates nasogastric tube insertion in anesthetized patients: A randomized clinical study

Journal of International Medical Research ◽

10.1177/0300060518772719 ◽

2018 ◽

Vol 46 (8) ◽

pp. 3124-3130 ◽

Cited By ~ 3

Author(s):

Han Joon Kim ◽

Su In Park ◽

Sang Yun Cho ◽

Min Jae Cho

Keyword(s):

General Anesthesia ◽

Success Rate ◽

Nasogastric Tube ◽

Insertion Time ◽

Control Group ◽

Magill Forceps ◽

Randomized Clinical Study ◽

Experimental Group ◽

Control Group Group

Objective Insertion of a nasogastric tube (NGT) in patients who have been intubated with an endotracheal tube while under general anesthesia can cause difficulties and lead to complications, including hemorrhage. A visualization-aided modality was recently used to facilitate NGT insertion. Some studies have focused on the role of modified Magill forceps, which have angles similar to those of the GlideScope blade (Verathon, Bothell, WA, USA). Methods Seventy patients were divided into a control group (Group C) and an experimental group (GlideScope and modified Magill forceps, Group M). Results The total NGT insertion time was significantly shorter in Group M than C (71.3 ± 22.6 vs. 96.7 ± 57.5 s; mean difference, –25.3 s; 95% confidence interval [CI], 20.8–71.5). There were also significantly fewer mean insertion attempts in Group M than C (1.0 ± 0.0 vs. 2.11 ± 0.93). The success rate for the first attempt in Group C was 37.1%, while that in Group M was 100% (relative risk, 2.7; 95% CI, 1.7–4.1). Conclusion The use of the GlideScope with modified Magill forceps for insertion of an NGT in patients who are already intubated and under general anesthesia will shorten the insertion time and improve the success rate.

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A Retrospective Audit of Dental Treatment Provided to Special Needs Patients under General Anesthesia During a Ten-Year Period

Journal of Clinical Pediatric Dentistry ◽

10.17796/1053-4628-42.2.13 ◽

2018 ◽

Vol 42 (2) ◽

pp. 155-160 ◽

Cited By ~ 8

Author(s):

Sreekanth Kumar Mallineni ◽

Cynthia Kar Y Yiu

Keyword(s):

Stainless Steel ◽

General Anesthesia ◽

Special Needs ◽

Recovery Time ◽

Dental Treatment ◽

Composite Restorations ◽

Dental Procedures ◽

Significant Difference ◽

Operative Recovery ◽

Amalgam Restorations

Objective: The purpose of this study was to perform a comprehensive audit of dental treatment provided to special needs patients (SNP) under general anesthesia (GA) over a ten-year period. Study design: Special needs patients who received dental treatment under GA as an in-patient at Queen Mary Hospital, Hong Kong SAR during the time period January 2002 and December 2011 were included in the study. The study population was divided into three groups, based on age (<6years, 6–12 years, >12 years). One-way ANOVA was used to evaluate the effect of “age group” on duration of treatment, post-recovery time, treatment procedures and utilization of different restorative materials. Kappa statistics were used for intra-examiner reliability. Results: A total of 275 patients (174 males and 101 females) were included in the study. The mean age of the patients at the time they received GA was 12.37±10.18 years. Dental procedures performed were mostly restorative in nature (47%). The >12 years group had significantly shorter treatment duration (p<0.05). No significant difference in post-operative recovery time was observed among the three age groups (p>0.05). The <6 years group received significantly less preventive, but more restorative procedures (p<0.05). Significantly fewer extractions were performed in the 6–12 years group (p<0.05). The use of composite restorations was significantly higher in the <6 years group; while amalgam restorations were more frequently used in the >12 years group (P<0.05). Stainless steel crowns were more frequently employed in SNP under 12 years of age (p<0.05). Intra-examiner reliability was good (k=0.94). Conclusions: Most of the dental procedures performed under GA on SNP were restorative procedures. For children less than 6 years of age, had longer treatment time under GA. Composite restorations and stainless steel crowns were more frequently used in the primary dentition and amalgam restorations were more frequently employed in the permanent dentition.

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Effects on Performance, Skin and Liver Histology of Different Clinoptilolite Levels in Rat Diets

Turkish Journal of Agriculture - Food Science and Technology ◽

10.24925/turjaf.v3i3.133-141.185 ◽

2014 ◽

Vol 3 (3) ◽

pp. 133

Author(s):

Dilek Şentürk Demirel ◽

Ramazan Demirel ◽

Muzaffer Aydın Ketani ◽

Kadri Balcı

Keyword(s):

Stainless Steel ◽

Adult Male ◽

Natural Zeolite ◽

Live Weight ◽

Experimental Period ◽

Group Iv ◽

Liver Histology ◽

Control Group ◽

Secondary Follicle

The objective of this study was to test the effects of dietary natural zeolite (clinoptilolite) on performance, skin and liver histology in rats. In this study, 24 10-week-old, weaned, adult male Spraque-Dawley rats with approximately 306 +- 18.93 g initial live weight were used. The rats were randomly divided into four groups with three replicates, including a control group and groups with one of three doses of clinoptilolite (2%, 4%, and 6%) in their diets. All the rats were fed these concentrates throughout the experimental period of 56 days. The animals were reared individually in stainless steel cages. There were no significant differences in the primary and secondary follicle numbers among groups, but the diameters of each follicle were found to be significant. The primary and secondary follicle numbers and diameters ranged from lowest to highest as follows: 2.00-2.33, 4.50-7.17; and 11.53-20.42, 57.63-102.12um, respectively. The differences occurred between the control group and group IV (containing 6% zeolite). In addition, the skin and liver histology results showed that there were no differences among the groups.

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Effect of Wild Chamomile Extracts on the Complex of Economic Benefits of Rabbit Meat

Food Processing Techniques and Technology ◽

10.21603/2074-9414-2019-4-643-651 ◽

2019 ◽

pp. 643-651

Author(s):

Roman Voroshilin ◽

Sergey Rassolov ◽

Elena Ul'rih ◽

Marina Kurbanova

Keyword(s):

Group Iv ◽

Feed Additives ◽

Control Group ◽

Group V ◽

Group Iii ◽

Group I ◽

Group Ii ◽

Rabbit Meat ◽

Experimental Group ◽

Wild Chamomile

Introduction. Nutrition has a great effect on the quality of life and longevity. Modern food industry pays much attention to the issue of obtaining high-quality and safe livestock products grown without feed antibiotics. The research objective was to study the effect of chamomile extract on a complex of economically useful traits of young rabbits and the qualitative characteristics of meat, as well as to determine the optimal dosage of chamomile extract. Study objects and methods. The experimental research was carried out on the animal farm of the Kuzbass State Agricultural Academy in 2018. Five experimental groups and one control group of young Californian rabbits were formed according to the principle of analogue pairs. Each group included 10 rabbits. From 70-day age, the animals of the experimental group I were supplemented with a phytobiotic feed additive based on wild chamomile extract at a dose of 0.5 g per rabbit per day. In experimental group II, each rabbit received 1 g per day; in experimental group III, it was 1.5 g per rabbit per day; in experimental group IV – 2.0 g per rabbit per day; in experimental group V – 2.5 g per head per day. The experiment lasted 30 days. Results and discussion. The best result was achieved in experimental group II. In the experimental groups, the rabbits demonstrated an increase in hemoglobin. The use of phytobiotic feed additives in the diet did not cause any pathological changes in internal organs. The average live weight at the end of the experiment, compared with the control group, was higher: experimental group I – by 0.82%, experimental group II – by 6.96%, experimental group III – by 5.01%, experimental group IV – by 3.73%, experimental group V – by 2.80% (P ˃ 0.01). An analysis of the chemical composition of rabbit meat after the experiment showed that the water content in the rabbit meat ranged from 76 to 77%, which suggests high water-holding properties. The high dietary qualities of the rabbit meat depended on the content of protein (20–22 wt%) and the low fat content (5–7%). These data make it possible to promote rabbit meat for dietary products. Conclusion. According to the slaughter indicators and the phytobiotic feed additives parameters of meat, the optimal dose of phytobiotic feed additives is 1 g per head per day.

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The use of CONOX as a guide to the general anesthesia on laparotomy patients compared with standard clinical care – A pilot study

Neurologico Spinale Medico Chirurgico ◽

10.36444/nsmc.v4i2.158 ◽

2021 ◽

Vol 4 (2) ◽

pp. 51-54

Author(s):

Brillyan Jehosua Toar ◽

I Putu Pramana Suarjaya ◽

IGAG Utara Hartawan ◽

Tjokorda Gde Agung Senapathi

Keyword(s):

Pilot Study ◽

General Anesthesia ◽

Severe Pain ◽

Clinical Care ◽

Postoperative Nausea And Vomiting ◽

Cognitive Disorder ◽

Control Group ◽

Intraoperative Awareness ◽

Depth Level ◽

Opioid Administration

Background: Avoiding excessive doses of anesthesia was fundamental, mainly to reduce the adverse effect of anesthesia. Electroencephalography (EEG)-based monitors can be used to measure the depth level of anesthesia and guide intraoperative hypnosis drug and opioid administration. This study aims to evaluate the benefit of using CONOX monitor when administering anesthesia drugs in laparotomy procedures. Method: Twenty patients aged 18-65 years with physical status ASA I-III who underwent major laparotomy surgery with general anesthesia total intravenous anesthesia (TIVA) were divided into two groups. Group A received general anesthesia guided with the CONOX monitor, while group B using standard clinical care. We later evaluate the total use of propofol and fentanyl, intraoperative hemodynamic profile, postoperative cognitive disorder (POCD), intraoperative awareness, postoperative nausea and vomiting (PONV), and moderate to severe pain in the post-anesthesia care unit (PACU). Results: The mean total propofol used is lower in CONOX group (63.6 ± 11.7 mcg/kg/min vs. 74 ± 17.87 mcg/kg/min). A similar result was obtained with fentanyl. The CONOX group use a lower total of fentanyl (212.5 ± 32.3 mcg vs. 249 ± 54.6 mcg) than the control group. POCD was found to be more prevalent in the control group (5 vs 2 patients). While there is no report of intraoperative awareness. Conclusion: The incidence of PONV and moderate to severe pain in PACU was similar between the two groups. This pilot study is a preliminary study to evaluate the benefit of using EEG-based monitors to adjust anesthesia drugs.

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