scholarly journals Polysomnographic Evaluation of OSA in Patients of Bronchial Asthma

2020 ◽  
Vol 5 (12) ◽  
pp. 595-598
Author(s):  
Dar Mohd Yousoof ◽  
Jamal Mohammad ◽  
Mir Shahnawaz ◽  
Shah Naveed Nazir ◽  
Dar Khursheed ◽  
...  
Keyword(s):  
General Population ◽  
Bronchial Asthma ◽  
Obstructive Sleep Apnoea ◽  
Risk Group ◽  
Communicable Disease ◽  
Sleep Apnoea ◽  
High Risk Group ◽  
North India ◽  
Obstructive Sleep ◽  
Asthma Patients

Introduction: Bronchial asthma a common non-communicable disease affecting more than 300 million people world-wide. Compared to general population quality of sleep is poor in asthma patients due to various factors like poor control of asthma, co-morbidities like allergic rhinitis and oesophageal reflex disease but little is known about the potential role of obstructive sleep apnoea. Aims and objectives: This study was conducted is to evaluate the association between Asthma and risk of developing Obstructive Sleep Apnoea. Materials and methods: This was a prospective design study conducted on 137 patients of diagnosed bronchial asthma attending out-patient department of a referral chest from north India after ethical clearance. These patients underwent Berlin score assessment first and later level-1 polysomnography to evaluate for OSA. Results: prevalence of PSG documented OSA observed was 53.3% which is significantly higher than the general population and there was significant association with increasing age as 54.7% of patients were in middle aged population (40-60 years) and obesity with 67.1% patients having OSA with BMI >30 compared to 37.5% prevalence only with BMI <30, as well as with severity of asthma. Besides OSA was seen in 91.9% of Berlin high risk group patients, while it was found in only 21.3 % of Berlin low-risk group. Conclusion: prevalence of OSA in asthma patients is significantly higher as compared to general population and there is significant positive co-relation between severity of asthma, BMI, increasing age and higher Berlin score with the overall prevalence of OSA.

Obstructive sleep apnoea is more prevalent in men with schizophrenia compared to general population controls: results of a matched cohort study

2018 ◽  
Vol 26 (6) ◽  
pp. 600-603 ◽  
Author(s):  
Hannah Myles ◽  
Andrew Vincent ◽  
Nicholas Myles ◽  
Robert Adams ◽  
Madhu Chandratilleke ◽  
...  
Keyword(s):  
Relative Risk ◽  
General Population ◽  
Obstructive Sleep Apnoea ◽  
Population Group ◽  
Sleep Apnoea ◽  
General Population Study ◽  
Obstructive Sleep ◽  
General Population Group ◽  
Relative Prevalence ◽  
Population Controls

Objectives: Obstructive sleep apnoea (OSA) may be more common in people with schizophrenia compared to the general population, but the relative prevalence is unknown. Here, we determine the relative prevalence of severe OSA in a cohort of men with schizophrenia compared to representative general population controls, and investigate the contribution of age and body mass index (BMI) to differences in prevalence. Methods: Rates of severe OSA (apnoea–hypopnoea index > 30) were compared between male patients with schizophrenia and controls from a representative general population study of OSA. Results: The prevalence of severe OSA was 25% in the schizophrenia group and 12.3% in the general population group. In subgroups matched by age, the relative risk of severe OSA was 2.9 ( p = 0.05) in the schizophrenia subjects, but when adjusted for age and BMI, the relative risk dropped to 1.7 and became non-significant ( p = 0.17). Conclusions: OSA is prevalent in men with schizophrenia. Obesity may be an important contributing factor to the increased rate of OSA.

Obstructive Sleep Apnoea, Atrial Fibrillation and Erectile Dysfunction – The OSAFED Syndrome – Is there More than Meets the Eye?

2015 ◽  
Vol 01 (01) ◽  
pp. 19
Author(s):  
Filip M Szymanski ◽  
Anna E Platek ◽  
Krzysztof J Filipiak ◽  
◽  
◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Erectile Dysfunction ◽  
Clinical Practice ◽  
Cardiovascular Risk ◽  
General Population ◽  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Clinical Syndromes ◽  
Obstructive Sleep

Obstructive sleep apnoea, atrial fibrillation and erectile dysfunction (OSAFED) syndrome is a new clinical entity recently introduced into clinical practice. The acronym consists of the first letters of the three clinical entities that comprise the disease, namely obstructive sleep apnoea (OSA), atrial fibrillation (AF) and erectile dysfunction (ED). As with many other clinical syndromes, OSAFED syndrome groups several clinical entities, which seemingly concern various organs and have different symptoms, but are closely associated by sharing risk factors and phenotype, and effecting cardiovascular risk in the same manner. OSA, AF and ED are also highly prevalent in the general population and tend to coexist. OSAFED syndrome was named as such to show how important diagnosis is of all these components in specific groups of patient. It is crucial for clinicians to improve the diagnosis and early treatment of all – OSA, AF and ED – and the incorporation of all these factors into one syndrome might help to facilitate this process.

scholarly journals Obstructive sleep apnoea as a risk factor for incident metabolic syndrome: a joined Episono and HypnoLaus prospective cohorts study

2018 ◽  
Vol 52 (5) ◽  
pp. 1801150 ◽  
Author(s):  
Camila Hirotsu ◽  
Jose Haba-Rubio ◽  
Sonia M. Togeiro ◽  
Pedro Marques-Vidal ◽  
Luciano F. Drager ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
General Population ◽  
Obstructive Sleep Apnoea ◽  
Arterial Oxygen Saturation ◽  
Sleep Apnoea ◽  
Arterial Oxygen ◽  
Obstructive Sleep ◽  
Increased Risk

Cross-sectional studies have demonstrated that obstructive sleep apnoea (OSA) and metabolic syndrome (MetS) are often associated, but whether a temporal relationship exists is unknown. We aimed to investigate the effect of OSA on the risk of developing MetS in the general population.A prospective study was conducted combining two population-based samples: Episono (Brazil) and HypnoLaus (Switzerland). MetS was assessed according to unified criteria. Polysomnography (PSG) was performed at baseline and follow-up in Episono, and at baseline in HypnoLaus. OSA was defined according to the apnoea–hypopnoea index as mild (≥5– <15 events h−1) and moderate-to-severe (≥15 events·h−1). We included 1853 participants (mean±sd age 52±13 years, 56% female) without MetS at baseline.After mean±sd 6±1 years, 318 (17.2%) participants developed MetS. Moderate-to-severe OSA was independently associated with incident MetS (OR 2.58, 95% CI 1.61–4.11) and increased the number of MetS components from baseline to follow-up through mediation of the percentage of time with arterial oxygen saturation <90%. Subset analysis in Episono confirmed that the increase in this parameter between baseline and follow-up PSGs represented a risk factor for incident MetS (OR 1.42, 95% CI 1.04–1.95, for each 10% increase).OSA is independently associated with an increased risk of developing MetS through mediation of nocturnal hypoxaemia in the general population.

Associations between obstructive lung disease and symptoms of obstructive sleep apnoea in a general population

2016 ◽  
Vol 12 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Trygve Müller Jonassen ◽  
Tomas Mikal Eagan ◽  
Bjørn Bjorvatn ◽  
Sverre Lehmann
Keyword(s):  
General Population ◽  
Lung Disease ◽  
Obstructive Sleep Apnoea ◽  
Obstructive Lung Disease ◽  
Sleep Apnoea ◽  
Obstructive Sleep

scholarly journals Mortality and morbidity in obstructive sleep apnoea–hypopnoea syndrome: results from a 30-year prospective cohort study

2020 ◽  
Vol 6 (3) ◽  
pp. 00057-2020 ◽  
Author(s):  
Sophie Dodds ◽  
Linda J. Williams ◽  
Amber Roguski ◽  
Marjorie Vennelle ◽  
Neil J. Douglas ◽  
...  
Keyword(s):  
Cohort Study ◽  
General Population ◽  
Prospective Cohort Study ◽  
Obstructive Sleep Apnoea ◽  
Prospective Cohort ◽  
Sleep Apnoea ◽  
Mortality And Morbidity ◽  
Obstructive Sleep

BackgroundObstructive sleep apnoea–hypopnoea syndrome (OSAHS) carries substantial negative health consequences. This study examines factors affecting mortality and morbidity according to continuous positive airway pressure (CPAP) use and predictors affecting CPAP adherence in a longitudinal cohort of OSAHS patients.Materials and methodsThis prospective, cohort study comprised 4502 patients who were diagnosed with OSAHS at a tertiary sleep disorders centre between 1982 and 2003. Of these, 1174 patients completed follow-up in 2012. Data collected included anthropometric, sleep and demographic characteristics, including comorbidities, ongoing medications and CPAP adherence. Patients were followed up for an average of 14.8±3.7 years.ResultsImputation analysis showed that long-term CPAP users (>5 years) were 5.63 times more likely to be alive at study end than non-CPAP users (95% CI: 4.83–6.58, p<0.001) and 1.74-times more likely than short-term CPAP users (≤5 years) (95% CI: 1.49–2.02, p<0.001). Females had a significantly higher mortality rate during the follow-up period (26.8% versus 19.6%, p<0.001). Respiratory mortality was more common in patients with OSAHS, in particular those who did not use CPAP, compared to the general population (17.2% versus 12.2%, p=0.002 respectively), whereas deaths from cancer were less common compared to the general population (16.2% versus 25.6%, p<0.001). Compared to CPAP users, non-CPAP-users had a significantly increased incidence of type II diabetes mellitus (DMII) (27.9% versus 18.7%, p=0.003), ischaemic heart disease (IHD) (25.5% versus 12.7%, p<0.001) and myocardial infarction (MI) (14.7% versus 4.2%, p<0.001) at long-term follow-up.ConclusionsLong-term CPAP use in men and women with OSAHS reduces mortality and decreases the incidence of DMII and cardiovascular disease.

High prevalence of undiagnosed obstructive sleep apnoea in the general population and methods for screening for representative controls

2012 ◽  
Vol 17 (3) ◽  
pp. 967-973 ◽  
Author(s):  
Laila Simpson ◽  
David R. Hillman ◽  
Matthew N. Cooper ◽  
Kim L. Ward ◽  
Michael Hunter ◽  
...  
Keyword(s):  
General Population ◽  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Obstructive Sleep ◽  
High Prevalence

scholarly journals Obstructive sleep apnoea in the general population: highly prevalent but minimal symptoms

2015 ◽  
Vol 47 (1) ◽  
pp. 194-202 ◽  
Author(s):  
Erna S. Arnardottir ◽  
Erla Bjornsdottir ◽  
Kristin A. Olafsdottir ◽  
Bryndis Benediktsdottir ◽  
Thorarinn Gislason
Keyword(s):  
General Population ◽  
Obstructive Sleep Apnoea ◽  
Clinical Symptoms ◽  
Population Sample ◽  
Sleep Apnoea ◽  
Middle Aged ◽  
Sleep Study ◽  
Psychomotor Vigilance Test ◽  
Obstructive Sleep ◽  
Osa Treatment

The aim was to assess the prevalence of obstructive sleep apnoea (OSA) as defined by an apnoea–hypopnea index (AHI) ≥15 in the middle-aged general population, and the interrelationship between OSA, sleep-related symptoms, sleepiness and vigilance.A general population sample of 40–65-year-old Icelanders was invited to participate in a study protocol that included a type 3 sleep study, questionnaire and a psychomotor vigilance test (PVT).Among the 415 subjects included in the study, 56.9% had no OSA (AHI <5), 24.1% had mild OSA (AHI 5–14.9), 12.5% had moderate OSA (AHI 15–29.9), 2.9% had severe OSA (AHI ≥30) and 3.6% were already diagnosed and receiving OSA treatment. However, no significant relationship was found between AHI and subjective sleepiness or clinical symptoms. A relationship with objective vigilance assessed by PVT was only found for those with AHI ≥30. Subjects already on OSA treatment and those accepting OSA treatment after participating in the study were more symptomatic and sleepier than others with similar OSA severity, as assessed by the AHI.In a middle-aged general population, approximately one in five subjects had moderate-to-severe OSA, but the majority of them were neither symptomatic nor sleepy and did not have impaired vigilance.

scholarly journals Pre-operative screening for obstructive sleep apnoea

2017 ◽  
Vol 26 (143) ◽  
pp. 160012 ◽  
Author(s):  
Johan Verbraecken ◽  
Jan Hedner ◽  
Thomas Penzel
Keyword(s):  
Risk Factor ◽  
Cardiovascular Risk ◽  
General Population ◽  
Obstructive Sleep Apnoea ◽  
Cardiovascular Risk Factor ◽  
Sleep Disordered Breathing ◽  
Sleep Apnoea ◽  
Surgical Interventions ◽  
Medical Interventions ◽  
Obstructive Sleep

Sleep disordered breathing, especially obstructive sleep apnoea (OSA), has a high and increasing prevalence. Depending on the apnoea and hypopnoea scoring criteria used, and depending on the sex and age of the subjects investigated, prevalence varies between 3% and 49% of the general population. These varying prevalences need to be reflected when considering screening for OSA. OSA is a cardiovascular risk factor and patients are at risk when undergoing medical interventions such as surgery. Screening for OSA before anaesthesia and surgical interventions is increasingly considered. Therefore, methods for screening and the rationale for screening for OSA are reviewed in this study.

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