scholarly journals Potensi Ekstrak Bawang Hitam sebagai Tabir Surya terhadap Paparan Sinar Ultraviolet

2020 ◽  
Vol 2 (1) ◽  
pp. 23
Author(s):  
Elvina Veronica ◽  
Putu Srinata Dampati
Keyword(s):  
Reactive Oxygen Species ◽  
Skin Cancer ◽  
Literature Review ◽  
Ultraviolet Radiation ◽  
Gene Mutations ◽  
Reactive Oxygen ◽  
Garlic Extract ◽  
Ultraviolet Rays ◽  
Oxygen Species ◽  
Literature Study

Abstract—Skin cancer is in the third rank in Indonesia. One of the causes of skin cancer is excessive exposure to ultraviolet rays from the sun. Ultraviolet radiation forms Reactive Oxygen Species that disrupts the regulation of the cell-matrix and causes photoaging and the burden of gene mutations that cause carcinogenesis. Black garlic is fermented garlic with a certain duration, temperature, and humidity. Black garlic has higher levels of antioxidants than garlic. Aimsresearch to determine the potential of black garlic extract as a sunscreen against ultraviolet rays. Literature study using literature review articles and research articles from international and national journals within the last ten years. Result research show black garlic extract protects the skin from ultraviolet radiation, acts as a photoprotector, prevents photoaging by stimulating fibroblast orders and prevents collagen I degradation, and prevents carcinogenesis. Black Garlic extract has a potency become sunscreen against ultraviolet exposure due to its antioxidant content. Further research is needed on the dosage and side effects. Keywords: antioxidants, black garlic, reactive oxgyen species, ultraviolet Abstrak— Kanker kulit menduduki peringkat tiga kanker terbanyak di Indonesia. Salah satu penyebab kanker kulit adalah paparan sinar ultraviolet matahari yang berlebih. Radiasi sinar ultraviolet membentuk reactive oxygen species yang mengganggu regulasi matriks sel dan menimbulkan photoaging serta memicu mutasi gen yang menyebabkan karsinogenesis. Bawang hitam merupakan bawang putih yang difermentasi dengan waktu, suhu, dan kelembapan tertentu. Bawang hitam mengandung antioksidan yang lebih tinggi dari bawang putih. Tujuan penelitian mengetahui potensi ekstrak bawang hitam sebagai tabir surya terhadap paparan sinar ultraviolet.Studi pustaka menggunakan artikel literature review dan artikel penelitian di jurnal internasional dan nasional dalam 10 tahun terakhir. Hasil: Ekstrak bawang hitam kaya akan antioksidan yang dapat melindungi kulit dari radiasi sinar ultraviolet, berperan sebagai fotoprotektor, mencegah photoaging dengan menstimulasi pembentukan fibroblas dan mencegah degradasi kolagen I, dan mencegah karsinogenesis. Ekstrak bawang putih berpotensi sebagai tabir surya terhadap paparan sinar ultraviolet karena kandungan antioksidannya. Perlu penelitian lebih lanjut tentang dosis dan efek samping yang ditimbulkan. Kata kunci: antioksidan, bawang hitam, reactive oxgyen species, ultraviolet

scholarly journals Potential Extract of Poinsettia (Euphorbia pulcherrima) as a sunscreen against UV exposure

2021 ◽  
Vol 3 (1) ◽  
pp. 83-92
Author(s):  
Elvina Veronica ◽  
Ni Kadek S Chrismayanti ◽  
Putu S Dampati
Keyword(s):  
Reactive Oxygen Species ◽  
Skin Cancer ◽  
Antioxidant Properties ◽  
Reactive Oxygen ◽  
Premature Aging ◽  
Uv Exposure ◽  
Ultraviolet Rays ◽  
Euphorbia Pulcherrima ◽  
Oxygen Species ◽  
Uv Rays

Exposure to UV (Ultraviolet) rays for a certain period can cause erythema, sunburn,photoallergies, and forms ROS (Reactive Oxygen Species) which leads to gene mutations,premature aging, and skin cancer. Skin cancer in Indonesia ranks third after cervical cancer andbreast cancer. Sunscreens can protect skin from UV exposure, although many sunscreens usechemicals that can cause contact dermatitis and other allergies. Various studies have shown thatplants with antioxidants can protect the skin from exposure to UV rays. Poinsettia (Euphorbiapulcherrima) is an ornamental plant with antioxidant properties. This literature review aims to examine the potential of the poinsettia as a sunscreen against UV rays. The extract of thepoinsettia leaf has the potential to be sunscreen against UV exposure because the antioxidantcontent of flavonoids and other photo protectors, inhibits ROS, thereby preventing mutations andthe process of ordering skin cancer. Antioxidants in poinsettia help heal burns and stimulatefibroblast to prevent premature photoaging due to excessive UV exposure. Conclusion, Kastubaleaf extract (Euphorbia Pulcherrima) has the potential as a sunscreen against UV exposure Keywords: Poinsettia; Ultraviolet (UV); Antioxidant; Reactive Oxygen Species (ROS)

scholarly journals How to express the antioxidant properties of substances properly?

2021 ◽  
Author(s):  
Małgorzata Olszowy-Tomczyk
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Literature Review ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Reactive Oxygen ◽  
The Body ◽  
Universal Method ◽  
Oxygen Species ◽  
Good Tool

AbstractOxidative stress, associated with an imbalance between the oxidants (reactive oxygen species) and the antioxidants in the body, contributes to the development of many diseases. The body’s fight against reactive oxygen species is supported by antioxidants. Nowadays, there are too many analytical methods, but there is no one universal technique for assessing antioxidant properties. Moreover, the applied different ways of expressing the results lead to their incompatibility and unreasonable interpretation. The paper is a literature review concerning the most frequent ways of antioxidant activities expression and for an easy and universal method of the obtained results discussion. This paper is an attempt to point out their disadvantages and advantages. The manuscript can support the searching interpretation of the obtained results which will be a good tool for the development of a number of fields, especially medicine what can help in the future detection and treatment of many serious diseases. Graphic abstract

scholarly journals Similar Stress Responses are Elicited by Copper and Ultraviolet Radiation in the Aquatic Plant Lemna gibba: Implication of Reactive Oxygen Species as Common Signals

2003 ◽  
Vol 44 (12) ◽  
pp. 1320-1329 ◽  
Author(s):  
T. Sudhakar Babu ◽  
Tariq A. Akhtar ◽  
Mark A. Lampi ◽  
Sridevi Tripuranthakam ◽  
D. George Dixon ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Ultraviolet Radiation ◽  
Stress Responses ◽  
Aquatic Plant ◽  
Reactive Oxygen ◽  
Lemna Gibba ◽  
Oxygen Species

scholarly journals Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

2015 ◽  
Vol 22 (12) ◽  
pp. 122008 ◽  
Author(s):  
H. Jablonowski ◽  
R. Bussiahn ◽  
M. U. Hammer ◽  
K.-D. Weltmann ◽  
Th. von Woedtke ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Ultraviolet Radiation ◽  
Vacuum Ultraviolet ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Plasma Jet ◽  
Oxygen Species ◽  
Vacuum Ultraviolet Radiation

Ugonin K Induces Cell Cycle Arrest and Apoptosis through Reactive Oxygen Species/Apoptosis Signal Pathway in Human Skin Cancer Cells

2013 ◽  
Vol 690-693 ◽  
pp. 1422-1425
Author(s):  
Leong Perng Chan ◽  
Tzung Han Chou ◽  
Guey Horng Wang ◽  
Ya Ping Tseng ◽  
Pin Ju Chen ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cell Cycle ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Cancer Cells ◽  
Human Skin ◽  
Antioxidant Activities ◽  
Reactive Oxygen ◽  
Hacat Cells ◽  
Oxygen Species

The incidence and mortality of skin cancer continue to rise because of the destruction of the ozonosphere in the earth. Skin cancer is divided into two groups by histological features – nonmelanoma skin cancers (NMSC) and melanoma. Cutaneous basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of NMSC are almost 75% among human skin malignancy cancer. In the preliminary bioactivity screening, the compound isolated from Helminthostachys zeylanica were evaluated antioxidant activities and interacted individually with serial human cancer cells, results that antioxidant activities of ugonin K were evaluated by measuring DPPH free-radical scavenging activities, and reducing power. Determination the reactive oxygen species (ROS) content and reduced glutathione (GSH) formation in H2O2-treated HaCaT cells by ugonin K. The cytotoxicity results show that ugonin K expressed less toxic to human keratinocytes (HaCaT cells) and human skin fibroblasts (Hs68 cells) than BCC cells, suggesting that ugonin K may have potential to be developed effective drugs for skin cancer cells without damaging skin normal cells. After treatment with ugonin K in BCC cells, cell cycle arrested in S-G2/M phase with a markedly increased apoptotic sub-G1 peak, mitochondria membrane potential (MMP) reduced, the expression of p53, Caspase-8, Caspase-9 and Caspase-3 revealed a more significant increased than the untreated control. Expected ugonin K has potential for an effective and specific drug to cancer cell, can minimize the damage to normal cell and provide a better therapeutic method to skin carcinoma.

scholarly journals Astaxanthin untuk Kesehatan Kardiovaskular

2021 ◽  
Vol 3 (2) ◽  
pp. 243-252
Author(s):  
Rana Salsabila Putri Laja
Keyword(s):  
Reactive Oxygen Species ◽  
Cardiovascular Disease ◽  
Literature Review ◽  
Full Text ◽  
Reactive Oxygen ◽  
Oxygen Species

Penyakit kardiovaskular adalah penyebab utama kematian di seluruh dunia. Adanya dislipidemia, gangguan toleransi glukosa, dan hipertensi dengan akumulasi lemak visceral yang disebut sindrom metabolik, meningkatkan risiko penyakit kardiovaskular. Sindrom metabolik sering ditandai dengan stres oksidatif, gangguan keseimbangan antara produksi reactive oxygen species dan pertahanan antioksidan. Sementara itu, astaxanthine diketahui  memiliki karakteristik antioksidan yang kuat, yang telah dilaporkan melampaui karakteristik β-karoten atau bahkan α-tokoferol. Penelitian ini merupakan  literature review yang melibatkan sebanyak 20 sumber pustaka dengan kata kunci yang digunakan antara lain ‘astaxanthin, cardiovascular disease dan xanthophyll carotenoid’ dengan tahun terbit antara 2006-2020. Abstrak dan full text jurnal dibaca dan dicermati, kemudian dilakukan analisis terhadap isi yang terdapat dalam tujuan penelitian dan hasil/temuan penelitian. Beberapa penelitian menunjukkan adanya beberapa manfaat yang dapat secara langsung atau tidak langsung dari astaxanthin berkaitan dengan potensi antioksidannya, termasuk kemampuannya untuk mengurangi atau menetralkan produksi ROS, sehingga meningkatkan aktivitas enzim pembersih radikal. Astaxanthin juga berperan sebagai anti inflamasi dan berperan dalam metabolisme lipid melalui efek hipokolesterolemik serta melindungi dari iskemia reperfusi. Astaxanthin di ketahui dapat memberikan manfaat bagi kesehatan kardiovaskular melalui berbagai mekanisme seperti peran antioksidan yang lebih baik, anti inflamasi, efek hipokolesterolemik dalam metabolisme lipid dan melindungi dari iskemia reperfusi.

TiO2/(BiO)2CO3 nanocomposites for ultraviolet filtration with reduced photocatalytic activity

2018 ◽  
Vol 6 (21) ◽  
pp. 5639-5650 ◽  
Author(s):  
Kathrin Bogusz ◽  
Moeava Tehei ◽  
Michael Lerch ◽  
Shi X. Dou ◽  
Hua K. Liu ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Photocatalytic Activity ◽  
Ultraviolet Radiation ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Subsequent Formation

TiO2 nanoparticles are typically used in sunscreens; however, they have been shown to exhibit cyto- and genotoxicity, which is related to the photocatalytic activity and the subsequent formation of reactive oxygen species when exposed to ultraviolet radiation.

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