scholarly journals Skin involvement in Burkitt lymphoma: rare clinical case

2020 ◽  
Vol 19 (1) ◽  
pp. 79-84
Author(s):  
T. T. Valiev ◽  
N. V. Matinyan ◽  
E. G. Gromova ◽  
M. A. Shervashidze ◽  
N. N. Tupitsyn ◽  
...  
Keyword(s):  
Rare Case ◽  
Clinical Case ◽  
Current Issue ◽  
Deep Understanding ◽  
Personal Data ◽  
Complete Response ◽  
Skin Involvement ◽  
Morphologic Characteristic ◽  
Clinical Presentations ◽  
Multiagent Chemotherapy

Birkitt lymphoma (BL) is one of the most studied and curable type of lymphoma in children. But inspite of lymphomagenesis deep understanding on immunologic, molecular and genetic levels, diagnosis of some rare clinical presentations of disease become challenging task for well-qualified clinicians. In the current issue we present rare case of skin involvement in pediatric 4 year old patient with disseminated BL. It is presented clinical and morphologic characteristic of specific skin presentation. Used multiagent chemotherapy with rituximab deliver the result of complete response. Skin site regression was found on 2d day of treatment. Parents give their agreement to use personal data, including fotos, in research and publications.

Tumours in children with Gorlin-Golts syndrome: rare case report

2022 ◽  
pp. 16-19
Author(s):  
М. А. Bolokhonova ◽  
V. Yu. Panarina ◽  
E. V. Sharapova ◽  
S. N. Mikhailova ◽  
Т. Т. Valiev ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Clinical Case ◽  
Current Issue ◽  
Federal State ◽  
National Medical ◽  
Clinical Presentations ◽  
Patient Health ◽  
Pediatric Oncologist ◽  
Rare Case Report

Gorlin-Golts syndrome is a genetic determined disease, characterized by multisystem features and associated with different malignancies, which are more aggressive with very unfavorable prognosis. By literature data this syndrome is a rare pathology. Observation and treatment of patients with Gorlin-Golts syndrome include syndromic correction of clinical presentations and detailed observation for early malignancies detection. In the current issue a survey of modern literature about Gorlin-Golts syndrome in children and clinical case of patient sent to Federal State Budgetary Institution» N. N. Blokhin National Medical Research Center of Oncology «of the Ministry of Health for malignancy diagnosis are presented. By global and own clinical experience about Gorlin-Golts syndrome it is necessary a genetic verification and make us perform a multidisciplinary control for such patient health with obligatory examination and observation of pediatric oncologist.

Complete response in metastatic renal cell carcinoma after radiotherapy and everolimus: a clinical case and review of the literature

2016 ◽  
Vol 28 (5) ◽  
pp. 432-434 ◽  
Author(s):  
Beatrice Detti ◽  
Giulio Francolini ◽  
Carlotta Becherini ◽  
Emanuela Olmetto ◽  
Irene Giacomelli ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Clinical Case ◽  
Complete Response ◽  
Review Of The Literature

Complete Response to Chemotherapy in Intra-Abdominal Desmoplastic Small round Cell Carcinoma. A Case Report

1998 ◽  
Vol 84 (3) ◽  
pp. 412-416 ◽  
Author(s):  
Mario De Lena ◽  
Maria Lucia Caruso ◽  
Franco Marzullo ◽  
Sergio Mancarella ◽  
Raffaele Armentano ◽  
...  
Keyword(s):  
Good Health ◽  
Complete Response ◽  
Complete Disappearance ◽  
Round Cell ◽  
Small Round Cell ◽  
Response To Chemotherapy ◽  
Lower Abdominal Quadrant ◽  
Antineoplastic Treatment ◽  
Multiagent Chemotherapy ◽  
The Right

Aims and background The authors report the case of a 23-year-old woman affected by intra-abdominal desmoplastic small round cell tumor (DSRCT) who obtained a complete response to multiagent chemotherapy. DSRCT is a rare, highly aggressive neoplasm generally arising in young people and seldom in females (about 20 cases described in the literature). Methods The patient underwent surgical resection of a large 15 × 15 cm mass located in the right lower abdominal quadrant, but after only 2 months later, two liver metastasis were noted. Thus, she was subjected to an aggressive antineoplastic treatment consisting of three groups of alternating non-cross resistant multiagent regimens administered every 21 days (cis-platin-etoposide-adriamycin-bleomicin; gemcitabine-ifosfamide-dacarbazine; methotrexate-5-fluorouracilfolinic acid) for a total of 9 administrations. Results After one cycle of treatment including the administration of all the three alternated schemes of chemotherapy, a complete disappearance of liver disease was noted. The treatment was relatively well-tolerated and the toxicity was acceptable. At present, after 15 months from diagnosis and 12 months after starting chemotherapy, the patient is disease-free and in good health. Conclusions Even though this study regards only a single patient, it is noteworthy because of the rarity of this neoplasm and because of the infrequent complete responses reported in the literature. The efficacy and manageability of the treatment, suggests that both the timing and schedule used could constitute an important therapeutical option for this aggressive and poorly chemo-responsive tumor.

scholarly journals Invasive aspergillosis with disseminated skin ınvolvement in a patient with acute myeloid leukemia: a rare case

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
Duygu Mert ◽  
Gülşen Iskender ◽  
Fazilet Duygu ◽  
Alparslan Merdin ◽  
Mehmet Sinan Dal ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Invasive Aspergillosis ◽  
Myeloid Leukemia ◽  
Rare Case ◽  
Invasive Pulmonary Aspergillosis ◽  
Skin Lesions ◽  
Immunocompromised Patients ◽  
Skin Involvement ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

Invasive pulmonary aspergillosis is most commonly seen in immunocompromised patients. Besides, skin lesions may also develop due to invasive aspergillosis in those patients. A 49-year-old male patient was diagnosed with acute myeloid leukemia. The patient developed bullous and zosteriform lesions on the skin after the 21st day of hospitalization. The skin biopsy showed hyphae. Disseminated skin aspergillosis was diagnosed to the patient. Voricanazole treatment was initiated. The patient was discharged once the lesions started to disappear.

scholarly journals Inflammatory Pseudotumour of Stomach in an old lady: a rare case report

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Azhar AH ◽  
Pasha MA ◽  
Hassan S ◽  
Zainal M ◽  
Rashidi A
Keyword(s):  
Case Report ◽  
Solid Tumor ◽  
Rare Case ◽  
Clinical Presentation ◽  
Inflammatory Pseudotumour ◽  
Secondary Neoplasms ◽  
Laboratory Techniques ◽  
Clinical Presentations ◽  
Rare Case Report ◽  
Adults And Children

Inflammatory pseudotumour (IPT) is a rare benign solid tumor in adults and children. The prevalence, etiology and pathogenesis of this condition are still uncertain. Despite the use of modern laboratory techniques and imaging, it is often difficult to make the diagnosis of IPT. Besides, occasionally the nonspecific morphological appearance and clinical presentation of the mass may mimic other more common primary or secondary neoplasms. IPT is commonly encountered in the lung and mediastinum. Other sites include abdomen (liver, pancreas, stomach, omentum), retroperitoneum, pelvis (bladder) and extremities in children. We report a rare case of gastric inflammatory pseudotumour in a 65-year-old female patient. Clinical presentations and its management along with review of literatures are presented.

scholarly journals CLINICAL CASE OF SUCCESFUL APPLICATION OF KADSYLA APPLICATION IN METASTATIC HER2 POSITIVE BREAST CANCER

2017 ◽  
pp. 56-58
Author(s):  
D. D. Sakaeva
Keyword(s):  
Breast Cancer ◽  
Targeted Therapy ◽  
Clinical Case ◽  
Complete Response ◽  
Trastuzumab Emtansine ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Pet Ct ◽  
Positive Breast Cancer

A clinical case of trastuzumab emtansine in therapy line 4 in patient with metastatic HER2positive breast cancer is provided. After 10  courses of targeted therapy by the drug a complete  response to the therapy was obtained. By results of PET CT conducted in the period from December 2015  to September 2017 the complete response is preserved.

scholarly journals Multi-lobed mesiodens with a palatal talon cusp: a rare case report

2010 ◽  
Vol 21 (4) ◽  
pp. 375-378 ◽  
Author(s):  
Nayaka Basavanthappa Nagaveni ◽  
Kagathur Veerbadrappa Umashankara ◽  
Sreedevi ◽  
Bokka Praveen Reddy ◽  
Nayaka Basavanthappa Radhika ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
Rare Case ◽  
Clinical Case ◽  
Treatment Plan ◽  
Radiographic Examination ◽  
Supernumerary Tooth ◽  
Anterior Teeth ◽  
Patient Reported ◽  
Rare Case Report ◽  
Maxillary Arch

Mesiodens is a midline supernumerary tooth commonly seen in the maxillary arch and the talon cusp is a rare dental developmental anomaly seen on the lingual surface of anterior teeth. This paper presents a rare clinical case of development of talon cusp in a mesiodens with multiple lobes, which interfered with both occlusion and appearance of an 11-year-old patient. During clinical interview, the patient reported difficulty on mastication. Clinical and radiographic examination revealed that a supernumerary tooth with completely formed root was causing an occlusal interference. The supernumerary tooth was diagnosed as multi-lobed mesiodens associated with a palatal talon cusp. The treatment plan consisted in the extraction of the supernumerary tooth followed by orthodontic treatment for diastema closure and tooth alignment.

scholarly journals A rare case of a maxillary fourth molar: Case report

2019 ◽  
Vol 29 (1) ◽  
pp. 125-128
Author(s):  
Valdelias Xavier Pereira ◽  
Alan Patricio Da Silva ◽  
Juliana Spat Carlesso ◽  
Marcelo Ferraz Campos
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Tooth Extraction ◽  
Clinical Case ◽  
Supernumerary Teeth ◽  
Impacted Tooth ◽  
X Ray ◽  
Dental Anomaly ◽  
Molar Teeth ◽  
Distomolar Teeth

Introduction: The objective of this clinical case report is to describe the presence of bilateral fourth molars. The occurrence of supernumerary teeth (ST) is a relatively unusual dental anomaly., It is even more unusual to find patients with distomolar teeth also denominated fourth molar teeth. Presentation of the case: This article describes a clinical case of a 24-year-old patient presenting with a maxillary fourth molar, who was diagnosed by dental x-ray, and surgical resolution of the case. Conclusion: Tooth extraction surgery was the clinical procedure chosen to treat the impacted tooth.

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