Menstruation and Suicide: An Exploratory Study

2007 ◽  
Vol 101 (2) ◽  
pp. 430-434 ◽  
Author(s):  
T. D. Dogra ◽  
Antoon A. Leenaars ◽  
Ravi Raintji ◽  
Sanjeev Lalwani ◽  
Shalini Girdhar ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Suicidal Behavior ◽  
Exploratory Study ◽  
India Institute ◽  
Control Group ◽  
New Delhi ◽  
Medical Sciences ◽  
Completed Suicide ◽  
The Relationship

Previous research has reported mixed findings on the effect of the menstrual cycle on suicidal behavior. The contribution of menstruation to completed suicide is also controversial, though the studies are very limited and have not been carefully designed. To explore the relationship, 217 autopsies on completed suicides were performed, matched to a control group at the All India Institute of Medical Sciences in New Delhi. The results show that 54.46% of people who died by suicide were menstruating (results excluded pregnancies), compared to 6.75% of the control group. Menstruation in those who completed suicide, compared to a control group, appeared to have an association with suicide. More research is warranted.

Menstruation and Suicide

Crisis ◽  
2009 ◽  
Vol 30 (4) ◽  
pp. 202-207 ◽  
Author(s):  
Antoon A. Leenaars ◽  
T.D. Dogra ◽  
Shalini Girdhar ◽  
S. Dattagupta ◽  
Lindsey Leenaars
Keyword(s):  
Menstrual Cycle ◽  
Histopathological Examination ◽  
Control Group ◽  
New Delhi ◽  
Medical Sciences ◽  
Tissue Storage ◽  
Suicide Methods ◽  
Completed Suicide ◽  
Methodological Problems ◽  
The Impact

Background: Previous research, albeit limited, has reported mixed findings on the impact of menstruation cycle on suicidal behavior. The contribution of menstruation to completed suicide is also controversial; the studies are, in fact, very limited and are not carefully designed. Aims: To examine whether the menstruation cycle impacts on suicide. Methods: In order to explore this relationship, 56 autopsies on completed suicides in females were performed and matched to a control group of 44 females who had died from other causes, at the All India Institute of Medical Sciences in New Delhi. Histopathological examination, a method of collecting tissue from the uterus through biopsy, was used to determine the stage of the menstrual cycle. Results: The results show that 25% of women who had died by suicide were menstruating at the time, compared to 4.5% of the control group; this is statistically (χ2) significant at the p < .002 level. Conclusions: Menstruation in the women who completed suicide, compared to a control group, appeared to have an association, though more research is warranted. Not only there are serious methodological problems in the study of menstruation and suicide (largely because of problematic tissue storage and examination), but also because of the need to understand the impact within a larger psychological, social, and cultural frame.

Serotonergic Genes and Suicidality

Crisis ◽  
2001 ◽  
Vol 22 (2) ◽  
pp. 54-60 ◽  
Author(s):  
Lisheng Du ◽  
Gabor Faludi ◽  
Miklos Palkovits ◽  
David Bakish ◽  
Pavel D. Hrdina
Keyword(s):  
Suicidal Ideation ◽  
Suicidal Behavior ◽  
Tryptophan Hydroxylase ◽  
Association Studies ◽  
Receptor Gene ◽  
Brain Regions ◽  
Depressive Illness ◽  
Control Group ◽  
Serotonergic Activity ◽  
Completed Suicide

Summary: Several lines of evidence indicate that abnormalities in the functioning of the central serotonergic system are involved in the pathogenesis of depressive illness and suicidal behavior. Studies have shown that the number of brain and platelet serotonin transporter binding sites are reduced in patients with depression and in suicide victims, and that the density of 5-HT2A receptors is increased in brain regions of depressed in suicide victims and in platelets of depressed suicidal patients. Genes that code for proteins, such as tryptophan hydroxylase, 5-HT transporter, and 5-HT2A receptor, involved in regulating serotonergic neurotransmission, have thus been major candidate genes for association studies of suicide and suicidal behavior. Recent studies by our group and by others have shown that genetic variations in the serotonin-system-related genes might be associated with suicidal ideation and completed suicide. We have shown that the 102 C allele in 5-HT2A receptor gene was significantly associated with suicidal ideation (χ2 = 8.5, p < .005) in depressed patients. Patients with a 102 C/C genotype had a significantly higher mean HAMD item #3 score (indication of suicidal ideation) than T/C or T/T genotype patients. Our results suggest that the 102T/C polymorphism in 5-HT2A receptor gene is primarily associated with suicidal ideation in patients with major depression and not with depression itself. We also found that the 5-HT transporter gene S/L polymorphism was significantly associated with completed suicide. The frequency of the L/L genotype in depressed suicide victims was almost double of that found in control group (48.6% vs. 26.2%). The odds ratio for the L allele was 2.1 (95% CI 1.2-3.7). The association between polymorphism in serotonergic genes and suicidality supports the hypothesis that genetic factors can modulate suicide risk by influencing serotonergic activity.

Application of Stem Cell Technology for Coronary Artery Disease at the All India Institute of Medical Sciences, New Delhi, India

2007 ◽  
Vol 10 (3) ◽  
pp. E231-E234 ◽  
Author(s):  
Balram Airan ◽  
Sachin Talwar ◽  
Shiv Choudhary ◽  
Akshay Bisoi ◽  
Ujjwal Chowdhury ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Stem Cell ◽  
Coronary Artery ◽  
India Institute ◽  
New Delhi ◽  
Medical Sciences ◽  
Stem Cell Technology ◽  
Cell Technology ◽  
Artery Disease

Pharmacovigilence practice for safety of medication system in India

2018 ◽  
Vol 7 (2) ◽  
pp. 216-221
Author(s):  
Shobharam Sahu ◽  
◽  
Poonam Rishishwar ◽  
Chhaya Rathod ◽  
◽  
...  
Keyword(s):  
Adverse Drug Reactions ◽  
India Institute ◽  
Family Welfare ◽  
New Delhi ◽  
Drug Reactions ◽  
Medical Sciences ◽  
Ministry Of Health ◽  
Regulatory Authorities ◽  
Pharmacovigilance Center ◽  
Uppsala Monitoring

Pharmacovigilance is very essential tool to ensure the safety of drug. It provides safety to patients in case of medication. Activity of pharmacovigilance is coordinates by National pharmacovigilance center in collaboration with international regulatory authorities (WHO, The Uppsala Monitoring center). Under the aegis of Ministry of Health & Family Welfare, Government of India, the Central Drugs Standard Control Organisation (CDSCO), New Delhi, has initiated a nation-wide pharmacovigilance programme, with the All India Institute of Medical Sciences (AIIMS), New Delhi as the National Coordinating Centre (NCC) for monitoring Adverse Drug Reactions (ADR)

Haptic input and balance control: An exploratory study examining normative messaging

2019 ◽  
pp. 135910531987744
Author(s):  
Kevin S Spink ◽  
Colin W Federow ◽  
Joel L Lanovaz ◽  
Alison R Oates
Keyword(s):  
Exploratory Study ◽  
Balance Control ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Descriptive Norm ◽  
Significant Difference ◽  
The Relationship ◽  
Positive Effect ◽  
Haptic Input

This study examined the effect of descriptive norm messaging information on the relationship between haptic input and balance control. Participants were randomly assigned to either a message group where they balanced with haptic input after receiving a descriptive norm message about the positive effect of haptic input or a control group. Findings from an analysis of covariance revealed a significant difference between the two groups. Those in the descriptive norm message group had better balance control than those in the control group. These findings suggest that efforts designed to improve balance control through haptic input may be enhanced through normative messaging.

Solitary plasmacytoma: 10 years’ experience at All India Institute of Medical Sciences, New Delhi

2012 ◽  
Vol 54 (8) ◽  
pp. 1665-1670 ◽  
Author(s):  
Saphalta Baghmar ◽  
Bidhu K. Mohanti ◽  
Atul Sharma ◽  
Lalit Kumar ◽  
Gaurav Prakash ◽  
...  
Keyword(s):  
India Institute ◽  
New Delhi ◽  
Solitary Plasmacytoma ◽  
Medical Sciences

scholarly journals First Detection of G12 Rotaviruses in Newborns with Neonatal Rotavirus Infection at All India Institute of Medical Sciences, New Delhi, India

2007 ◽  
Vol 45 (11) ◽  
pp. 3824-3827 ◽  
Author(s):  
P. Ray ◽  
S. Sharma ◽  
R. K. Agarwal ◽  
K. Longmei ◽  
J. R. Gentsch ◽  
...  
Keyword(s):  
India Institute ◽  
New Delhi ◽  
Medical Sciences ◽  
Rotavirus Infection

scholarly journals Investigating the association of regional anesthesia during labor with postpartum depression

2020 ◽  
Author(s):  
Esmat Barooti ◽  
Bahman Malek ◽  
Safoora Honarmand ◽  
Mohammadreza Moshari ◽  
Seyed Alshohadaei SM
Keyword(s):  
Body Mass Index ◽  
Intensive Care ◽  
Postpartum Depression ◽  
Regional Anesthesia ◽  
Significant Relationship ◽  
Control Group ◽  
Medical Sciences ◽  
Normal Delivery ◽  
Factors Affecting ◽  
The Relationship

Introduction: Postpartum depression (PPD) is a common disorder and a type of clinical depression that affects mothers during the first 4 weeks after childbirth. Considering the destructive effects of this disease on mothers' behavior, identifying the factors affecting PPDand using proper methods in normal delivery is important. The aim of this study was to determine the relationship between regional anesthesia (RA) during labor and the incidence of PPDin women referred to hospitals affiliated to Shahid Beheshti University of Medical Sciences. Methodology: In this study, 200 pregnant women referred to hospitals of Shahid Beheshti University of Medical Sciences during 2015 to 2017 entered into two equal groups, Group R, administered RA, and Group C; control group without RA according to their desire. Each group consisted of 100 parturients, and the two groups were compared for the incidence of PPD and the association of depression with RA during labor. Results: Based on the obtained data, the participants in the two groups did not differ significantly in terms of age, body mass index (BMI), duration of delivery phases and depression in the first week of postpartum. However, the severity of pain in different phases of delivery was different due to the use of anesthetic for one of the groups. No significant relationship between RA and depression was observed in the first week after childbirth. However, RA has a significant relationship with PPD in the 4th week, so that the use of RA reduces the incidence of PPD in the 4th week (p = 0.066). Conclusion: We conclude that the use of regional anesthesia will not have a significant effect on postpartum depression in the first week, but it reduces the incidence of postpartum depression in the 4th week after childbirth. Citation: Barooti E, Malek B, Honarmand S, Moshari M, Alshohadaei SMS. Investigating the association of regional anesthesia during labor with postpartum depression. Anaesth pain & intensive care 2019;23(3):----  Received – 30 May 2018, Reviewed – 23 August, 26 October 2018, 2 May, 4 May, 16 June, 14 September 2019; Revised – 14 October 2018, 18 March, 10 June 2019; Accepted- 14 September 2019

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