Within-Response Force Variations Accompanying Differentiation of Duration in Rats

1977 ◽  
Vol 40 (3_suppl) ◽  
pp. 1271-1284 ◽  
Author(s):  
Stephen C. Fowler ◽  
Robert J. Filewich ◽  
Mark R. Leberer
Keyword(s):  
Relative Frequency ◽  
Response Duration ◽  
The Other ◽  
Force Sensing ◽  
Response Force ◽  
Individual Response ◽  
Frequency Distributions ◽  
Joint Force ◽  
Force Criterion ◽  
Water Reinforcer

By using a force-sensing isometric manipulandum, response force waveforms were recorded from rats performing a duration differentiation. For 2 rats exteroceptive cues were correlated with response force exceeding the force criterion and with attainment of the 1.60-sec. duration required for reinforcement. The other 3 rats received no exteroceptive support, the water reinforcer being delivered upon response termination. In the last phase of the experiment, reinforcement was contingent upon holding response force within a force “band” for a specified time. Relative frequency distributions of response duration indicated that differentiation of duration was more accurate in the presence of exteroceptive cues than in the absence of such stimuli. Spectral analysis of individual response waveforms indicated that rhythmic force oscillations (2 to 6 hz) predominated, despite the subjects' reliance on exteroceptive stimuli. Introduction of the joint force-band-duration contingency reduced but did not completely abolish the oscillations for both cued and uncued subjects. Over-all the results suggest that the rhythmic force variations observed here may be unselected or elicited components of the response rather than manifestations of a proprioceptive self-cueing process.

NATO adaptation to current challenges and mechanisms of Ukraine’s cooperation with the North Atlantic Treaty Organization

2019 ◽  
pp. 73-81
Author(s):  
Oleh Poshedin
Keyword(s):  
North Atlantic ◽  
Task Force ◽  
Response Force ◽  
Cyber Attack ◽  
Adaptation Measures ◽  
Joint Force ◽  
Security Environment ◽  
The North ◽  
The North Atlantic ◽  
Area Of Influence

The purpose of the article is to describe the changes NATO undergoing in response to the challenges of our time. Today NATO, as a key element of European and Euro-Atlantic security, is adapting to changes in the modern security environment by increasing its readiness and ability to respond to any threat. Adaptation measures include the components required to ensure that the Alliance can fully address the security challenges it might face. Responsiveness NATO Response Force enhanced by developing force packages that are able to move rapidly and respond to potential challenges and threats. As part of it, was established a Very High Readiness Joint Task Force, a new Allied joint force that deploy within a few days to respond to challenges that arise, particularly at the periphery of NATO’s territory. NATO emphasizes, that cyber defence is part of NATO’s core task of collective defence. A decision as to when a cyber attack would lead to the invocation of Article 5 would be taken by the North Atlantic Council on a case-by-case basis. Cooperation with NATO already contributes to the implementation of national security and defense in state policy. At the same time, taking into account that all decision-making in NATO based on consensus, Ukraine’s membership in the Alliance quite vague perspective. In such circumstances, in Ukraine you often can hear the idea of announcement of a neutral status. It is worth reminding that non-aligned status did not save Ukraine from Russian aggression. Neutral status will not accomplish it either. All talks about neutrality and the impossibility of Ukraine joining NATO are nothing but manipulations, as well as recognition of the Ukrainian territory as Russian Federation area of influence (this country seeks to sabotage the Euro-Atlantic movement of Ukraine). Think about it, Moldova’s Neutrality is enshrined in the country’s Constitution since 1994. However, this did not help Moldova to restore its territorial integrity and to force Russia to withdraw its troops and armaments from Transnistria.

Deceptive Ambiguity by Police and Prosecutors

2017 ◽  
Author(s):  
Roger W. Shuy
Keyword(s):  
Speech Acts ◽  
Relative Frequency ◽  
The Other ◽  
Cooperative Principle ◽  
Case Examples ◽  
Police Interviews ◽  
Performance Errors ◽  
Criminal Suspects ◽  
The Government ◽  
Speech Events

Much is written about how criminal suspects, defendants, and undercover targets use ambiguous language in their interactions with police, prosecutors, and undercover agents. This book examines the other side of the coin, describing fifteen criminal investigations demonstrating how police, prosecutors, undercover agents, and complainants use deceptive ambiguity with their subjects, which leads to misrepresentations of the speech events, schemas, agendas, speech acts, lexicon, and grammar. These misrepresentations affect the perceptions of judges and juries about the subjects’ motives, predispositions, intentions, and voluntariness. Deception is commonly considered intentional while ambiguity is often excused as unintentional performance errors. Although perhaps overreliance on Grice’s maxim of sincerity leads some to believe this, interactions of suspects, defendants, and targets with representatives of law are adversarial, non-cooperative events that enable participants to ignore or violate the cooperative principle. One effective way the government does this is to use ambiguity deceptively. Later listeners to the recordings of such conversations may not recognize this ambiguity and react in ways that the subjects may not have intended. Deceptive ambiguity is clearly intentional in undercover operations and the case examples illustrate that the practice also is alive and well in police interviews and prosecutorial questioning. The book concludes with a summary of how the deceptive ambiguity used by representatives of the government affected the perception of the subjects’ predisposition, intentionality and voluntariness, followed by a comparison of the relative frequency of deceptive ambiguity used by the government in its representations of speech events, schemas, agendas, speech acts, lexicon, and grammar.

scholarly journals Effects of relative frequency and delay interval of knowledge of results (KR) in the acquisition of motor skills

2006 ◽  
Vol 1 (1) ◽  
pp. 53-63
Author(s):  
Leandro R. Palhares ◽  
Alessandro T. Bruzi ◽  
Guilherme M. Lage ◽  
João V. A. P. Fialho ◽  
Herbert Ugrinowitsch ◽  
...  
Keyword(s):  
Motor Skills ◽  
Delay Interval ◽  
Motor Skill ◽  
Relative Frequency ◽  
The Other ◽  
Tennis Ball ◽  
Knowledge Of Results ◽  
Target Time ◽  
Serial Task

The purpose of the present study was to identify the effects of relative frequency and delay interval of Knowledge of Results (KR) in the acquisition of a serial motor skill. Sixty students were randomly distributed in 2 experiments, with three groups in each experiment (n = 10). The Experiment 1 investigated the effects of the KR frequency without KR delay interval and the Experiment 2 investigated the effects of the KR frequency with KR delay interval (3 seconds) in the acquisition of a serial motor skill. The serial task consisted of putting a tennis ball into six holes, positioned in a wood platform in a previously determined target time. In both experiments, the subjects performed 60 trials in target time of 2,700 ms, in the acquisition phase. In the Experiment 1, the results showed superiority of G33 in relation to the other groups, during the tests. In the Experiment 2, the results did not show any difference among the groups. These results are discussed with respect to the effect of KR delay interval, showing the role of combination of the variables.  

Two Non-senses of “Probability”

2021 ◽  
pp. 47-76
Author(s):  
Wayne C. Myrvold
Keyword(s):  
Relative Frequency ◽  
The Other ◽  
Objective Probability ◽  
Sequence Of Events ◽  
Principle Of Indifference ◽  
Long Run ◽  
Eighteenth And Nineteenth Centuries

This chapter engages in some ground-clearing. Two concepts have been proposed to play the role of objective probability. One is associated with the idea that probability involves mere counting of possibilities (often wrongly attributed to Laplace). The other is frequentism, the idea that probability can be defined as long-run relative frequency in some actual or hypothetical sequence of events. Associated with the idea that probability is merely a matter of counting of possibilities is a temptation to believe that there is a principle, called the Principle of Indifference, which can generate probabilities out of ignorance. In this chapter the reasons that neither of these approaches can achieve its goal are rehearsed, with reference to historical discussions in the eighteenth and nineteenth centuries. It includes some of the prehistory of discussions of what has come to be known, misleadingly, as Bertrand’s paradox.

scholarly journals Psychological Health of Disaster Response Forces: Need to Prioritise

2019 ◽  
Vol 65 (1) ◽  
pp. 136-151
Author(s):  
Anita Bhatnagar Jain
Keyword(s):  
Psychological Stress ◽  
Psychological Health ◽  
Exponential Growth ◽  
Psychological Assessment ◽  
Disaster Response ◽  
First Responders ◽  
Decisive Role ◽  
The Other ◽  
Response Force ◽  
National Disaster

Globally, various kinds of disasters, both natural and human induced, have seen an exponential growth. Generally, the focus is on the loss and sufferings of the survivors and the other affected population, but rarely is the first responders’ stress taken into account or mentioned in any review or report. However, psychological stress of forty National Disaster Response Force (NDRF) personnel of various hierarchies, who were part of the 2013 Uttarakhand disaster rescue team, has been assessed. The analysis indicates that the nature and place of work and duties of the first responders played a decisive role in the prevalence of higher psychological stress levels. Thus, it is imperative to include the psychological assessment and care of the first responders in the policies, plans and trainings for disaster management.

scholarly journals Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials

Rheumatology ◽  
2020 ◽  
Author(s):  
Monica S M Persson ◽  
Joanne Stocks ◽  
Aliya Sarmanova ◽  
Gwen Fernandes ◽  
David A Walsh ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Random Sequence ◽  
The Other ◽  
Response To Treatment ◽  
Individual Response ◽  
Clinical Trial Registration ◽  
Knee Oa ◽  
Baseline Pain Intensity ◽  
Painful Knee ◽  
Equal Efficacy

Abstract Objectives To determine individual responses to ibuprofen gel or capsaicin cream for painful, radiographic knee OA using a series of n-of-1 trials. Methods Twenty-two participants were allocated 5% ibuprofen gel (A) and 0.025% capsaicin cream (B) in random sequence (AB or BA). Patients underwent up to 3 treatment cycles, each comprising one treatment for 4 weeks, an individualized washout period (maximum 4 weeks), then the other treatment for 4 weeks. Differential (ibuprofen or capsaicin) response was defined when change-from-baseline pain intensity scores (0–10 NRS) differed by ≥1 between treatments in ≥2 cycles within a participant. Results A total of 104 treatment periods were aggregated. Mean pain reduction was 1.2 (95% CI: 0.5, 1.8) on ibuprofen and 1.6 (95% CI: 0.9, 2.4) on capsaicin (P = 0.221). Of 22 participants, 4 (18%) had a greater response to ibuprofen, 9 (41%) to capsaicin, 4 (18%) had similar responses, and 5 (23%) were undetermined. Conclusion Irrespective of equal efficacy overall, 59% of people displayed a greater response to one treatment over the other. Patients who do not benefit from one type of topical treatment should be offered to try another, which may be more effective. N-of-1 trials are useful to identify individual response to treatment. Clinical trial registration https://clinicaltrials.gov, NCT03146689

Response Variables in the Estimation of Relative Frequency

1965 ◽  
Vol 21 (3) ◽  
pp. 867-873 ◽  
Author(s):  
Gordon F. Pitz
Keyword(s):  
Contrast Effect ◽  
Relative Frequency ◽  
The Other ◽  
Total Frequency ◽  
Response Modes ◽  
Relationship Of ◽  
Log Ratio ◽  
The Relationship ◽  
Response Variables

6 groups of 20 Ss each observed a sequential series of digits, 4s and 8s, and judged what proportion (P) of the total was made up by one of the digits. Three kinds of response were used, estimates of percentage, the ratio of one frequency to the other, and the two frequencies themselves. P was varied from .1 to .9, either by holding total frequency constant, or by holding one frequency constant and varying the second. All responses were converted to log ratios, and the relationship of log estimated ratio to log ratio was found to be generally linear. There were significant differences in scales of proportion for the three response modes, and for the two methods of P variation. Percentages, ratios and frequencies gave different slopes, which were possibly a function of an assimilation-contrast effect. Differences due to methods of P variation were thought to result primarily from differences in total frequency at certain levels of P.

Properties of random functions

1956 ◽  
Vol 52 (4) ◽  
pp. 672-686 ◽  
Author(s):  
D. S. Palmer
Keyword(s):  
Cross Correlation ◽  
The Other ◽  
Horizontal Line ◽  
Time Lags ◽  
Frequency Distributions ◽  
Random Functions ◽  
Wave Radio ◽  
Long Wave ◽  
Radio Signals ◽  
Highly Correlated

ABSTRACTThis paper deals with the relationships of the maxima, minima and zeros of two random functions of known autocorrelations and cross-correlation, based on the work of Rice(4). Ratcliffe(3) and Briggs and Spencer(2) discuss a similar problem in connexion with a ‘Phillips Record’ of an experiment in ionospheric reflexion. In this experiment there are two highly correlated reflected signals, their maxima coming close together, and the record shows the time lags between a maximum on one signal and a maximum on the other. Briggs and Page (1) have made an experimental study of the distribution of the differences between the positions of the maxima of two highly correlated random functions, using EDSAC to construct the functions. In §§ 3–7 the frequency distributions of intervals between successive zeros and maxima, and of the lengths of intercepts by a horizontal line, are considered. This has applications to the study of the fading of long-wave radio signals, where the tune differences between successive maxima of the amplitude have been investigated.

Molecular Response of CML Patients to INFα Based Treatment or to STI Based Therapy.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 4872-4872
Author(s):  
Debora Luzi ◽  
Rosanna Capozzi ◽  
Annamaria Rauco ◽  
Roberta Pace ◽  
Emilio Donti ◽  
...  
Keyword(s):  
Myeloid Leukemia ◽  
Response Duration ◽  
Cytogenetic Response ◽  
The Other ◽  
Entire Group ◽  
Molecular Response ◽  
Rt Pcr ◽  
Molecular Remission ◽  
First Time

Abstract Introduction: Continous improving results have been obtained during last two decades in the control of Ph’positive chronic myeloid leukemia(CML). However the final goal of molecular remission remains difficult to obtain even in the STI age. Aims : Evaluation of the rate of molecular response to IFNα,IFNα based treatment,to STI or to STI-INFα combination was analized in 100 consecutive Ph+ CML patients observed in a single Institution over a period of 20 years. Patients, Methods and Results All patients were treated at the time of diagnosis (87) or late (13) during the course of their disease. Distribution according to treatment was: INFα,63pts (late or early:13,50);INFα-ARA-C combination,20pts;STI,14 pts;STI-INFα association, 3 pts. Two pts, both initially assigned to INFα-ARA-C combination, were crossed-over to STI, one because relapsing off-therapy after a long lasting continous (25 mths) molecular remission and the other in cytogenetic response because intolerant to the initial treatment. In addition, other 3 pts patients, with persistent complete cytogenetic, but not molecular remission to INFα or INFα-ARA-C combination were subsequentially trated with the STI-IFNα association. At present,99/100 pts are evaluable. The median times of follow-up for the entire group and form the different treatment subgroups are: late IFNα 154 months(42–263); early IFNα, 71 months(1–197); IFNα-ARA-C, 61 months(5–203); STI- IFNα,78 mths(11–47), STI,31 mths(3–41). A complete kariotypic remission(CKR) was observed in 15/63 IFNα treated pts, in 10/20 IFNα-ARA-C pts group, in 10/13 cases of STI group and in 3 /3 pts who received STI-IFNα. A molecular response(RT-nested PCR, JQ Guo, Leukemia: 2002,15,2447–53) was observed in 4/15,2/10,5/10 and in 2/3 CKR pts initially trated with the different modalities listed above. Response was confirmed from 2 to 7 consecutive or not consecutive times in the 2/4 cases responsive to INFα, in the 2 cases responsive to INFα-ARA-C combination,4/5cases responsive to STI and in 2/3 cases responsive to STI-IFNα association. The 2nd and the 3rd molecular remission to STI were obtained in the patient molecularly and cytogenetically relapsed off-therapy and, for the first time from the diagnosis, in the other patient in CKR to IFNα-ARA-C combination and crossed to STI treatment. Furthermore, all 3 cases, in CKR, but not molecular response to other treatments at the time of cross-over to STI-IFNα combination, achieved a persistent (in 2 to 3 tests over a period ranging from 6+ to 12+ mths) molecular remission. The first interval between the start of the treatment and the first molecular response varied from 12 to 52, from 3 to 22, from 11 to 24, from 5 to 11 mths in the groups initially treated with IFNα, IFNα-ARA-C, STI or STI-IFNα respectively. The 2 pts, crossed-over to STI alone, both, obtained a response after 29 mths of therapy. In addition in the 3 pts crossed-over to STI-IFNα therapy, the molecular response was obtained after 14,23 and 25 mths from the start of last treatment. Conclusion It is not possible to achieve any conclusion regarding the treatment effect on molecular response duration because of the different length of follow-up of various groups of patients. However in responsive patients to IFN alone or combined to ARA-C or STI, consecutive negative RT-PCR tests were observed more frequently than in patients receving STI alone.

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