scholarly journals Pseudoexfoliation syndrome and episcleral venous pressure

2017 ◽  
Vol 16 (1) ◽  
pp. 32-37
Author(s):  
V. V. Potemkin ◽  
E. V. Ageeva
Keyword(s):  
Matched Control ◽  
Important Determinant ◽  
Venous Pressure ◽  
Main Group ◽  
Pseudoexfoliation Syndrome ◽  
Control Group ◽  
Episcleral Venous Pressure ◽  
Age Related ◽  
Temporal Quadrant ◽  
And Control

Introduction. Pseudoexfoliation syndrome (PEX) is a relatively widespread generalized age-related disease, in which abnormal fibrillar extracellular material is produced and accumulates in many tissues including vessels. Glaucoma occurs more commonly in eyes with PEX than in those without it. Episcleral venous pressure (EVP) is an important determinant of intraocular pressure (IOP). It seems reasonable to evaluate episcleral venous pressure in patients with PEX. Purpose. To evaluate episcleral venous pressure in patients with PEX. Methods. 540 eyes of 270 patients were enrolled in the prospective study. We evaluated episcleral venous pressure. Results. EVP in total vein compression in lower-nasal quadrant (mmHg) in main group(with PEX) was 14.0±3.29, in control group No. 1 (non PEX, adults) - 14.38±3.77, in control group No. 2 (non PEX, young) - 10.91±2.34. EVP in total vein compression in lower-temporal quadrant (mmHg) in main group was 15.1±3.31, in control group No. 1 - 15.76±3.45, in control group No. 2 - 11.00±2.16. Difference in episcleral venous pressure between main group and age-matched control group No. 1 was not significant, and between main group and control group No. 2 was significant. Conclusion. EVP level is not influenced by PEX, but is influenced by age.

Thromboembolic complications prevention in the obstetric practice

2017 ◽  
pp. 19-24
Author(s):  
O.V. Grishchenko ◽  
◽  
V.V. Bobrytska ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Comparison Group ◽  
Main Group ◽  
Control Group ◽  
Efficacy And Safety ◽  
Thromboembolic Complications ◽  
Moderate Risk ◽  
Obstetric Practice ◽  
Thrombotic Complications ◽  
And Control

The objective: To evaluate the clinical efficacy and safety of Enoxaparin-Pharmex for the prevention of thrombotic complications (pulmonary embolism) in the postoperative period in patients with moderate risk of these complications. Patients and methods. The study included 50 women after a caesarean section had an average degree of risk of pulmonary embolism. Patients were divided into the main group (n=25) and control group (n=25) in accordance with the treatment: patients of the main group received postoperative Еnoxaparin- Pharmex, group comparisons enoxaparin sodium (brand foreign manufacturer’s). Patients in both groups received the drug at a dose of 20 mg for 5 days, 1 time per day subcutaneously. Results. The research data analysis showed identity results of hemostasiogram of patients in the main group and the comparison group, no side effects after treatment in both groups. Conclusion. The clinical studies suggest the drug Enoxaparin-Pharmex is effective, safe LMWH, which can be used to prevent troboembolic complications, including post-operative treatment in obstetric practice. Spectrum of Enoxaparin-Pharmex can be extended to the prevention and treatment of thromboembolic conditions of varying severity with appropriate doses of the drug. Key words: Enoxaparin-Pharmex, prevention of pulmonary embolism.

scholarly journals THE IMPORTANCE OF EDUCATION TO REDUCE SELF-DESTRUCTIVE NAIL HABITS

2021 ◽  
Vol 4 ◽  
pp. 491-499
Author(s):  
Ilze Upeniece ◽  
Monta Beltiņa
Keyword(s):  
Clinical Practice ◽  
General Education ◽  
Statistical Significance ◽  
Target Population ◽  
Control Group ◽  
Age Related ◽  
Nail Changes ◽  
Group 2 ◽  
And Control ◽  
Traumatic Damage

Onychophagia and onychotillomania are rarely seen in clinical practice and are considered undervalued. The study aims were to determine the prevalence of onychophagia and onychotillomania habit in the patient group with hand nail damage and control group, to determine which would be the target population to educate. Patients were interviewed about self-destructive habits. Excel and SPSS were used for data analysis. In the nail damage group, 28.6% of the respondents showed self-destructive habits and past habits – 31.4%. In the control group, the result was 22.9% and 31.4%. For 74.3% of patients the cause of nail damage was skin disease (including 61.54% of respondents with nail damage who have psoriasis), for 5.7% it was age-related nail changes, for 20% traumatic damage and for 57.14% of them it was a result of self-destructive habit. In the nail damage group both – present and past self-destructive habits are higher than in the control group, but it has no statistical significance (p=0.785). 1)The prevalence of onychophagia and onychotillomania does not differ between patients and control group. 2)General education of the population is necessary to actualize this problem, which can worsen nail changes.

scholarly journals ANALYSIS OF THE DYNAMICS OF FUNCTIONAL OCCLUSION INDICATORS IN THE CONSTRUCTION OF OCCLUSION SURFACES OF ORTHOPEDIC STRUCTURES

2020 ◽  
Vol 73 (12) ◽  
pp. 2651-2656
Author(s):  
Svitlana P. Yarova ◽  
Sergii O. Turchenenko ◽  
Iryna M. Tkachenko ◽  
Yuriy Yu. Yarov
Keyword(s):  
Functional Condition ◽  
Masticatory Muscles ◽  
Main Group ◽  
Suggested Method ◽  
Control Group ◽  
Orthopedic Treatment ◽  
Functional Parameters ◽  
Occlusal Surfaces ◽  
Left And Right ◽  
And Control

The aim: Is to evaluate the effectiveness of the proposed method of constructing occlusal surfaces of orthopedic structures by monitoring the dynamics of functional indicators of occlusion and the functional condition of the masticatory muscles. Materials and methods: The object of the study was made up by 64 patients with included defects of the dentition of the 3rd class according to Kennedy. Patients were divided into two equal groups – the main group (patients were treated by using the suggested method of construction of occlusal surfaces of orthopedic structures) and control (dentition defects were replaced according to the traditional protocol). Results: The results of evaluating the effectiveness of the proposed method showed that the index of symmetry of the anterior bundles of the temporal muscles dropped by 18.5%, the index of symmetry of the masticatory muscles reduced by 22%, the torque of the mandible reduced by 32%, the index of stabilizing occlusal – by 27%, relative efforts of balance disturbance for more than 10 % regarding the left and right reduced by a factor of 4.4, the rate of opening time was 1.5 times higher than before, the rate of time of opening of the jaws – 1.8 times. Conclusions: The use of the suggested method of orthopedic treatment with temporary structures leads to probable changes in the studied functional parameters in comparison with the control group (p <0,05).

scholarly journals Reading Fluency in Children and Adolescents Who Stutter

2021 ◽  
Vol 11 (12) ◽  
pp. 1595
Author(s):  
Mona Franke ◽  
Philip Hoole ◽  
Ramona Schreier ◽  
Simone Falk
Keyword(s):  
Children And Adolescents ◽  
Reading Fluency ◽  
Developmental Stages ◽  
Matched Control ◽  
Control Group ◽  
Articulation Rate ◽  
Prosodic Phrasing ◽  
Age Related ◽  
Prosodic Boundaries ◽  
Decoding Ability

Speech fluency is a major challenge for young persons who stutter. Reading aloud, in particular, puts high demands on fluency, not only regarding online text decoding and articulation, but also in terms of prosodic performance. A written text has to be segmented into a number of prosodic phrases with appropriate breaks. The present study examines to what extent reading fluency (decoding ability, articulation rate, and prosodic phrasing) may be altered in children (9–12 years) and adolescents (13–17 years) who stutter compared to matched control participants. Read speech of 52 children and adolescents who do and do not stutter was analyzed. Children and adolescents who stutter did not differ from their matched control groups regarding reading accuracy and articulation rate. However, children who stutter produced shorter pauses than their matched peers. Results on prosodic phrasing showed that children who stutter produced more major phrases than the control group and more intermediate phrases than adolescents who stutter. Participants who stutter also displayed a higher number of breath pauses. Generally, the number of disfluencies during reading was related to slower articulation rates and more prosodic boundaries. Furthermore, we found age-related changes in general measures of reading fluency (decoding ability and articulation rate), as well as the overall strength of prosodic boundaries and number of breath pauses. This study provides evidence for developmental stages in prosodic phrasing as well as for alterations in reading fluency in children who stutter.

scholarly journals Polymorphisms of pleiotropic genes ABCC11 and ACE in Abkhazians and the longevity phenomenon

2019 ◽  
pp. 29-36
Author(s):  
С.В. Макаров ◽  
М.К. Карапетян ◽  
К.Б. Квеквескири ◽  
В.А. Спицын
Keyword(s):  
Multiple Drug Resistance ◽  
Control Group ◽  
Multiple Drug ◽  
Ace Gene ◽  
Caucasus Region ◽  
Gene Insertion ◽  
Vital Functions ◽  
Genotype Frequencies ◽  
Age Related ◽  
And Control

Изучение наследственных факторов в детерминации долголетия представляется весьма актуальным в связи с ростом средней продолжительности жизни, поиском возможностей продления «здорового» периода в позднем отногенезе. Феномен высокой продолжительности жизни всегда вызывал особый интерес исследователей, а его изучение представляется наиболее перспективным в популяциях с достаточно большой долей долгожителей. С давних времен известны случаи ярко выраженного активного долголетия в регионе Кавказа. У долгожителей Абхазии темпы соматического развития, уровень обменных процессов и меньшая интенсивность возрастной инволюции скелета указывали на относительно «здоровый» тип старения. Среди генетических факторов, которые потенциально могли бы играть важную роль в достижении долголетия, особенно перспективным представляется изучение плейотропных генов, действие которых проявляется во множественных эффектах и обладающих высокой функциональной значимостью. Среди них особый интерес представляют те, которые определяют эффективность функционирования сердечно-сосудистой системы, а также особенности, влияющие на темп созревания и старения организма. К числу таких генов можно отнести ген ангиотензин-превращающего фермента (ACE) и ген множественной лекарственной устойчивости (ABCC11). Целью исследования был поиск закономерностей в характере распределения полиморфных вариантов плеойтропных генов ABCC11 и ACE в популяции абхазов в связи с возрастом обследуемых и наличием долгожителей в выборке. В качестве материала исследования были собраны образцы клеток буккального эпителия от коренных жителей Абхазии, подразделенных на две группы: старшего возраста (75-101 год, 79 человек) и контрольную ( 97 индивидов в возрасте от 16 до 33 лет ). Анализ распределений частот генотипов и аллелей полиморфизма 538G>A (rs17822931) гена ABCC11 показал, что группы старшего возраста и контроля очень сходны между собой и достоверные различия между выборками отсутствуют. Генотипирование по инсерционно-делеционному полиморфизму гена ACE (rs1799752) осуществлялось методом ПЦР-ПДАФ. Для контрольной группы абхазов установлены следующие частоты генотипов: II = 0,186; ID = 0,412; DD = 0,402, частоты аллелей I и D оказались равны 0,392 и 0,608 соответственно. Группа старшего возраста по частотам генотипов существенно не отличалась от контроля, генотипы II/ID/DD были распределены в соотношении 0,088/0,380/0,532, а частоты аллелей I и D оказались равны 0,278 и 0,722 соответственно. В результате исследования выявлено, что частота аллеля делеции по инсерционно-делеционному полиморфизму в гене ACE в старшей возрастной группе абхазов достоверно повышена по сравнению с контрольной группой. The study of the phenomenon of longevity is the most promising in populations with a fairly large proportion of centenarians. Since old times cases of pronounced active longevity have been widely known in the Caucasus region. The complexity of age-related processes of aging assumes the involvement of multiple complex factors that have affect on life expectancy. Therefore the study of the pleiotropic genes with their multiple effects and functions could be helpful in that case. The angiotensin I-converting enzyme (ACE) gene and the multiple drug resistance gene ( ABCC11) are of great interest because of their high importance for essential vital functions. The aim of the study was the search for correlations in the frequencies distribution of polymorphic variants of pleoitropic genes ABCC11 and ACE in the population of Abkhazians with the longevity. The material included the DNA samples from indigenous residents of Abkhazia. They were divided into two groups: older age (N = 79) and control (N = 97). The differences in the frequencies distribution of 538G>A genotypes and alleles of the gene ABCC11 in the older group and control were not significant. ACE gene insertion-deletion polymorphism ( rs1799752) genotyping was performed by PCR-AFLP. The genotype frequencies were : II = 0.186; ID = 0.412; DD = 0.402, allele frequencies I and D were equal to 0.392 and 0.608 for the control group of Abkhazians. The older group did not differ significantly from the control in genotype frequencies, the ratio for II/ID/DD genotypes were as 0.088/0.380/0.532, and the frequencies of alleles I and D corresponded to 0.278 and 0.722. The obtained results revealed that the ACE gene deletion allele frequency was significantly increased in the older group of Abkhazians.

scholarly journals Root Dimensions in Patients with Mild Hypodontia and a Control Group

2019 ◽  
Vol 13 (04) ◽  
pp. 574-580
Author(s):  
Khaled Khalaf ◽  
Zahra Seraj ◽  
Hesham Hussein ◽  
Mahmoud Mando
Keyword(s):  
Matched Control ◽  
Permanent Teeth ◽  
Cervical Region ◽  
Control Group ◽  
Third Molars ◽  
Control Groups ◽  
Implant Placement ◽  
Dental Hospital ◽  
The University ◽  
And Control

Abstract Objectives The aim of this study was to compare root dimensions (length and mesiodistal widths) between subjects with mild hypodontia and an age- and sex-matched control group. Materials and Methods Root dimension measurements of all permanent teeth excluding third molars were made on standardly taken orthopantomograms of 50 individuals (25 hypodontia and 25 controls) attending the University of Sharjah Dental Hospital. The length and two mesiodistal widths were measured for each fully formed root. The length of the root was measured digitally by drawing a line from the midpoint and bisecting the mesiodistal cemento-enamel junction (CEJ) of the tooth and extended to its apex. The mesiodistal widths of each root were measured at the cervical region and at half way of and perpendicular to the length of the root. Statistical Analysis Two sample t-tests were used to compare root dimension measurements between the hypodontia and control groups. Results There were no significant differences between genders with regard to root length or widths measurements, and therefore genders were combined for further analysis. Patients with hypodontia have significantly shorter root lengths than controls for the upper central incisors, upper canines, first premolars, and lower first molars (p < 0.05). Similarly, root width at the midpoint of the root was found to be less in hypodontia group than that in controls for the upper central incisors, lower first premolars, upper first molars, and all second premolars (p < 0.05). Similar pattern of differences was found with regard to the root width at the cervical region (p < 0.05). Conclusions Patients with hypodontia have shorter and narrower roots of the whole permanent dentition except the upper lateral incisors, lower incisors, lower canines, and all second molars when compared with controls. In effect, this may affect the orthodontic treatment planning and implant placement.

Increased Mean Platelet Volume in Patients With Aortic Stenosis

2010 ◽  
Vol 17 (6) ◽  
pp. E17-E20 ◽  
Author(s):  
Ercan Varol ◽  
Akif Arslan ◽  
Habil Yucel ◽  
Mehmet Ozaydin ◽  
Dogan Erdogan ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Platelet Activation ◽  
Mean Platelet Volume ◽  
Matched Control ◽  
Control Group ◽  
Study Group ◽  
Platelet Volume ◽  
Echocardiographic Examination ◽  
The Mean ◽  
And Control

Background: Systemic thromboembolism is a serious complication in patients with aortic stenosis (AS). Previous studies have demonstrated that platelet activation occurs in patients with AS. The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation in patients with AS. Patients and Methods: The study group consisted of 43 patients with AS. An age-, gender-, and body mass index−matched control group consisted of 35 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants. Results: Mean platelet volume was significantly higher among patients with AS when compared with the control group (8.7 ± 1.0 vs 7.9 ± 0.9 fL, respectively; P = .001). Conclusion: We have shown that MPV was significantly elevated in patients with AS compared to control participant.

The effects of shungite on somatoform disorders in athletes

2015 ◽  
Vol 9 (1) ◽  
pp. 0-0
Author(s):  
Белых ◽  
E. Belykh ◽  
Несмеянов ◽  
A. Nesmeyanov ◽  
Борисова ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Somatoform Disorders ◽  
Muscle Tone ◽  
Main Group ◽  
Control Group ◽  
Undesirable Effect ◽  
Biomedical Technologies ◽  
Instrumental Effect ◽  
And Control

The article demonstrates the importance of the application of new biomedical technologies in the correction of somatoform disorders in athletes. In observation were 86 athletes playing sports. Comprehensive clinical, psychological and instrumental examination showed that 11, 3% of them have some somatic pathology, but the complaint didn’t match up to this pathology, she had overdone character. Moreover, in this group in 36.4% of cases, there are previous histories of acute infectious diseases. The athletes were divided into two equal groups (main and control) by 43 people. In the main group, the athletes were treated orally with shungite in the form of tablets, in the control group - the psycho-pharmacotherapy. The same clinical and instrumental effect was observed in both groups. In the control group the undesirable effect of reducing muscle tone, drowsiness was detected. This allowed the authors to consider that it is expedient to use shungite for the correction of sym-tomatics in athletes with somatoform disorders.

scholarly journals Naturally acquired antibodies to Bacillus anthracis protective antigen in vultures of southern Africa

2008 ◽  
Vol 75 (2) ◽  
Author(s):  
P. C.B. Turnbull ◽  
M. Diekman ◽  
J. W. Killian ◽  
W. Versfeld ◽  
V. De Vos ◽  
...  
Keyword(s):  
South Africa ◽  
Bacillus Anthracis ◽  
South African ◽  
Southern Africa ◽  
Protective Antigen ◽  
Control Group ◽  
North West ◽  
Age Related ◽  
Significant Difference ◽  
And Control

TURNBULLP, P.C.B. DIEKMANNM,M., KILIAN, J.W., VERSFELDW, W.,DE VOS, V., ARNTZENL, L.,WOLTER, K., BARTELS, P. & KOTZE, A. 2008.N aturally acquired antibodies to Bacillusa nthracisp rotective antigeni n vultureso f southern Africa. Onderstepoort Journal of Veterinary Research, T5:95-102 Sera from 19 wild caught vultures in northern Namibia and 15 (12 wild caught and three captive bred but with minimal histories) in North West Province, South Africa, were examined by an enzyme-linked immunosorbenats say( ELISA)f or antibodiesto the Bacillus anthracis toxin protective antigen (PA). As assessed from the baseline established with a control group of ten captive reared vultures with well-documented histories, elevated titres were found in 12 of the 19 (63%) wild caught Namibian birds as compared with none of the 15 South African ones. There was a highly significant difference between the Namibian group as a hole and the other groups (P < 0.001) and no significant difference between the South African and control groups (P > 0.05). Numbers in the Namibian group were too small to determine any significances in species-, sex- or age-related differences within the raw data showing elevated titres in four out of six Cape Vultures, Gyps coprotheress, six out of ten Whitebacked Vultures, Gyps africanus, and one out of three Lappet-faced Vultures, Aegypiust racheliotus, or in five of six males versus three of seven females, and ten of 15 adults versus one of four juveniles. The results are in line with the available data on the incidence of anthrax in northern Namibia and South Africa and the likely contact of the vultures tested with anthrax carcasses. lt is not known whether elevated titre indicates infection per se in vultures or absorption of incompletely digested epitopes of the toxin or both. The results are discussed in relation to distances travelled by vultures as determined by new tracking techniques, how serology can reveal anthrax activity in an area and the issue of the role of vultures in transmission of anthrax.

scholarly journals Measurement of glycosaminoglycans in canine synovial fluid and its correlation with the cause of secondary osteoarthritis, age and body weight

2012 ◽  
Vol 81 (3) ◽  
pp. 287-294 ◽  
Author(s):  
Radka Andrysíková ◽  
Hana Kudláčková ◽  
Miroslav Toman ◽  
Alois Nečas
Keyword(s):  
Body Weight ◽  
Synovial Fluid ◽  
Mean Value ◽  
Control Group ◽  
Joint Cartilage ◽  
Mean Values ◽  
Secondary Osteoarthritis ◽  
Age Related ◽  
Normal Body Weight ◽  
And Control

Glycosaminoglycans are natural components of healthy joint cartilage and they also appear in healthy synovial fluid. An increased amount of glycosaminoglycans in synovial fluid is believed to be a marker of secondary osteoarthritis, regardless of its primary cause. The aim of our study was to define the relationship between glycosaminoglycans in the synovial fluid and joint disorders, age, and body weight. The samples of synovial fluid were obtained from dogs suffering from secondary secondary osteoarthritis (n = 35) and from control dogs (n = 18); control dogs had normal body weight. The results were compared among joints of dogs with secondary osteoarthritis divided into groups according to the criteria mentioned above and control dogs. Glycosaminoglycan concentrations in synovial fluid were measured using dimethylmethylene blue assay. The lowest mean value of glycosaminoglycans in synovial fluid was measured in the control group. Significantly higher glycosaminoglycan content (P < 0.05) was found in synovial fluid isolated from obese dogs compared to control dogs. Furthermore, we observed an age-related trend, in which the highest mean values were reached either in old dogs or pups. Despite the absence of significant differences in glycosaminoglycan values among dogs suffering from various types of secondary secondary osteoarthritis, the highest mean values were measured in fragmented coronoid processus group. Our data suggest that abnormally increased body weight has an impact on glycosaminoglycan concentration in synovial fluid which may imply faster degradation and turnover of joint cartilage. Such observation has not yet been published in veterinary medicine.

Sign in / Sign up

Export Citation Format

Share Document