scholarly journals PERBANDINGAN PROFIL GLUKOSA DARAH PASIEN STROKE ISKEMIK DAN STROKE HEMORAGIK DI RSUP FATMAWATI TAHUN 2018

Author(s):  
Intan Rahma Husna ◽  
Riezky Valentina Astari ◽  
Tuty Rizkianti

Stroke is the death of brain cells due to lack of blood flow and oxygen to the brain by blockage or rupture of an artery. Stress hyperglycemia in acute stroke may worsen the clinical outcome and the prognosis of stroke. The purpose of this study is to find out and compare blood glucose profile between ischemic stroke and hemorrhagic stroke. This is an observational analytic cross-sectional research using consecutive sampling. Data was obtained through medical record from January to December 2018 in RSUP Fatmawati with each group of stroke consisting of 74 samples. Data was processed using SPSS 2017. Mann-Whitney test shows a significant difference in random blood glucose levels between ischemic stroke and hemorrhagic stroke (p = 0.024), with the median value of random blood glucose level during ischemic stroke is 115.50 mg / dL and hemorrhagic stroke is 136.50 mg / dL. The results also shows a significant difference in fasting blood glucose levels between ischemic stroke and hemorrhagic stroke (p = 0.042), with the median value of fasting blood glucose level for ischemic stroke is 116.50 mg / dL and hemorrhagic stroke is 125.50 mg / dL. A significant difference is also seen in 2 hours post-prandial glucose level between ischemic stroke and hemorrhagic stroke (p = 0.028), with the median value of 2 hours post-prandial glucose level of  ischemic stroke is 130 mg / dL and hemorrhagic stroke is 147.50 mg / dL. Keywords: Ischemic Stroke; Hemorrhagic Stroke; Random Blood Glucose; Fasting Blood Glucose; 2 Hour Post-Prandial Blood Glucose AbstrakStroke adalah kematian sel-sel otak akibat hilangnya pasokan darah dan oksigen ke otak karena adanya  hambatan atau ruptur arteri yang menuju otak. Pada stroke fase akut dapat terjadi hiperglikemia reaktif yang dapat memperburuk  keluaran klinis dan prognosis stroke. Penelitian ini dilakukan untuk mengetahui dan membandingkan profil glukosa darah antara stroke iskemik dan stroke hemoragik. Penelitian ini bersifat analitik observasional dengan desain potong lintang dan pemilihan sampel consecutive sampling. Data didapat dari rekam medis periode Januari-Desember 2018 di RSUP Fatmawati dengan masing-masing kelompok stroke sebanyak 74 sampel. Pengolahan data dilakukan dengan program SPSS tahun 2017. Uji Mann-Whitney menunjukkan adanya perbedaan bermakna kadar Glukosa Darah Sewaktu antara stroke iskemik dengan stroke hemoragik (p = 0,024), dengan nilai median Glukosa Darah Sewaktu stroke iskemik adalah 115,50 mg/dL dan stroke hemoragik adalah 136,50 mg/dL. Hasil juga menunjukkan adanya perbedaan bermakna kadar Glukosa Darah Puasa antara stroke iskemik dan stroke hemoragik (p = 0,042), dengan nilai median Glukosa Darah Puasa stroke iskemik adalah 116,50 mg/dL dan stroke hemoragik adalah 125,50 mg/dL, serta adanya perbedaan bermakna kadar Glukosa Darah 2 Jam Post-Prandial antara stroke iskemik dan stroke hemoragik (p = 0,028), dengan nilai median Glukosa Darah 2 Jam Post-Prandial stroke iskemik adalah 130 mg/dL dan stroke hemoragik adalah 147,50 mg/dL.

2012 ◽  
Vol 19 (06) ◽  
pp. 786-788
Author(s):  
KIRAN BUTT ◽  
FARAH DEEBA ◽  
HAVAIDA ATTIQUE

Objective: The objective of the present study was to determine the changes in the glucose level and lipid profile in patients withpolycystic ovarian syndrome (PCOS). Study Design: Descriptive study. Place and Duration of the study: This study was conducted atInstitute of Molecular Biology and Biotechnology, The University of Lahore from June 2009 to June 2010. Patients and Methods: Total 50patients with PCOS were included and 50 age-matched control subjects were also selected for comparison. Their glucose levels and lipidprofile were assessed using commercial kits. The data thus obtained was subjected to statistical analysis. Results: Significant differences(P<0.05) in fasting blood glucose level and individual parameters of lipid profile were observed in women with PCOS. A higher prevalence ofhypertriglyceridemia, hypercholesterolemia, higher LDL, lower HDL and higher fasting blood glucose levels was explored in PCOS womenthan controls. Conclusions: Abnormal glucose level and lipid profile in PCOS women showed that these women are at an increased risk ofdeveloping diabetes and subsequently cardiovascular diseases.


2019 ◽  
Vol 9 (1) ◽  
pp. 86 ◽  
Author(s):  
Zulkarni Zulkarni

This Research was conducted to determine the effect of ethanol extract from red chilli (Capsicum annuum L)in lowering blood glucose levels of hyperglycemic male white mices. This study used 30 malewhitemices and divided into 6 groups: negative control group, the positive control group, the treatmentgroup withdosage of 200 mg / kgweight, 400 mg / kgwieght, 600 mg / kg weight and a comparison group with glibenclamide with dosage of 5 mg / kgweightadministered orally for 21 days. The level of fasting blood glucose was checked 6 days after dexamethasone induced, and after the ethanol extract of red chilies on day 7th, 14th, and 21st. The data was analyzed statistically with one –way and two-way Anova by usingSPSS16 program and proceed with the test Duncan to look the significant difference between treatments. The results showed that the ethanol extract from red chilies with a dosage of 200mg / kgweight, 400mg / kgweight, 600 mg / kgweight showed the effect in lowering blood sugar levels in male white mices hyperglycemia significantly (p <0.05). The duration ethanol extract of red chili affected blood glucose levels. The most effective duration in lowering blood glucose levels is the administration of a preparation within 21 days.


Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1410-1414
Author(s):  
Gnanamoorthy Kothai ◽  
Acksa Alex ◽  
Aruna Bholenath Patil ◽  
Athanallur Raman Malathy ◽  
Prasanna Karthik Suthakaran

Diabetes Mellitus (DM) is a systemic disorder characterized by hyperglycemia either due to insulin resistance or insulin deficiency. This can lead to many serious life-threatening complications if not managed properly by regular monitoring of glycemic status. Prevalence of fear of needles in the society make people non-compliant to regular monitoring. Thus, there is a need for a non-invasive method for determining the glycemic status of the individual. Salivary Glucose has the potential to be one such tool. This study aimed to find whether a correlation between fasting blood glucose levels and fasting salivary glucose levels could be established in diabetic and non-diabetic individuals. 50 patients with DM and 50 patients without DM were studied. 5 ml of venous blood and 5 ml of unstimulated saliva after overnight fasting were collected from each participant and processed using standardized enzymatic methods. The data was analyzed using SPSS software. There was a strong and very significant positive correlation (r=0.800, p=0.001) between fasting salivary glucose levels and fasting blood glucose levels in patients with DM whereas the correlation was weak and insignificant in patients without DM (r=0.111, p=0.441). The cut off value for diagnosing DM was found to be ˃ 2.2mg/dl with 100% specificity and 100% sensitivity.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Louis E. Ugahari ◽  
Yanti M. Mewo ◽  
Stefana H.M. Kaligis

Abstract: Blood glucose must be maintained in a constant concentration. Hyperglycemia, an increase of blood glucose level, can be a symptom of diabetes mellitus. One of the factors that affect the blood glucose level is physical activity. Low physical activity can be influenced by work. Sedentary lifestyle is identic with office workes. Office workers do not enough time to do physical activity. This study was aimed to describe the fasting blood glucose level among office workers. This was a descriptive study with a cross sectional design. Respondents were obtained by using total sampling method. There were 52 respondents in this study consisted of 25 males and 27 females. The results showed that 45 respondents (86.54%) had normal fasting blood glucose levels, 5 respondents (9.62%) had high fasting blood glucose levels (hyperglycemia), and 2 respondents (3.84%) had low fasting blood glucose levels (hypoglycemia). The maximum value was 243 mg/dL, the minimum value was 63 mg/dL, the median value was 83 mg/dL, the average value was 94.42 mg/dL, and standard of deviation was 37.85 mg/dL. Conclusion: Most office workers had normal blood glucose levels.Keywords: fasting blood glucose, office workers Abstrak: Glukosa darah dalam tubuh manusia harus dijaga dalam konsentrasi yang konstan. Kadar glukosa darah dalam tubuh yang meningkat (hiperglikemia) dapat menjadi gejala penyakit diabetes mellitus. Salah satu faktor yang memengaruhi kadar glukosa darah ialah aktivitas fisik. Aktivitas fisik yang kurang dapat dipengaruhi oleh pekerjaan. Pola hidup sedentary lifestyle identik dengan pekerja kantor dewasa ini. Pekerja kantor tidak memiliki waktu untuk terlibat dalam aktivitas fisik yang cukup. Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah puasa pada pekerja kantor. Jenis penelitian ialah deskriptif dengan desain potong lintang. Pemilihan responden dilakukan dengan metode total sampling. Responden terdiri dari 25 orang laki-laki s dan 27 orang perempuan. Hasil penelitian mendapatkan 45 responden (86,54%) memiliki kadar glukosa darah puasa normal, 5 responden (9,62%) memilki kadar glukosa darah puasa tinggi (hiperglikemia), dan 2 responden (3,84%) memilki kadar glukosa puasa rendah (hipoglikemia). Hasil pengukuran kadar glukosa darah puasa mendapatkan nilai maksimum 243 mg/dL, nilai minimum 63 mg/dL, nilai median 83 mg/dL, nilai rata-rata 94,42 mg/dL dan standar devisiasi 37,85 mg/dL. Simpulan: Sebagian besar pekerja kantor masih memiliki kadar glukosa darah puasa yang normal. Kata kunci: glukosa darah puasa, pekerja kantor


2020 ◽  
Vol 9 (1) ◽  
pp. 61-67
Author(s):  
Natalia Desy Putriningtyas ◽  
Intan Permatasari ◽  
Dita Oktaviani ◽  
Anastasia Servia Raha ◽  
Siti Wahyuningsih

Background: Polyphenols, antioxidants, dietary fiber, and vitamin contained in the red dragon fruit peel. Red dragon fruit peel can be processed into marmalade. Red dragon fruit peel marmalade has the potential to be a functional food. Functional food is food that has a physiological function based on scientific studies.Objectives: The objective of this study is to analyze the effect of red dragon fruit peel marmalade on fasting blood glucose levels, HDL, LDL, and triglycerides levels of hypercholesterolemic Wistar rats.Methods: This study used a pre-&post-test control group design. Hypercholesterolemic male Wistar rats were randomly assigned into five groups. Hypercholesterolemia was induced by 1% cholesterol powder and 0.5% cholic acid for two weeks. All groups received standard chow. Samples were grouped into five groups: K-; K+; K1 (0.94 g/kg b.wt/day); K2 (1.41 g/kg b.wt/day); K3 (1.88 g/kg b.wt/day). The intervention was carried out for 28 days. GDP level was measured using the GOD-PAP. HDL, LDL, and triglyceride were analyzed with spectrophotometry. GDP, HDL, LDL, and triglyceride levels were measured twice before fasting. A paired t-test and one-way ANOVA were used to analyze the data.Results: The result showed that K-; K1; K2; K3 had a significant difference between groups before and after the intervention (p<0.05). Red dragon fruit peel Marmalade was able to reduce the levels of GDP, LDL, triglycerides, and increase HDL (p <0.05).Conclusion: Red dragon fruit peel marmalade reduced fasting blood glucose levels, LDL, triglyceride levels, and increased HDL levels of hypercholesterolemic Wistar rats.


Author(s):  
Meiriani . ◽  
Yuneldi Anwar ◽  
Puji Pinta Omas Sinurat

Background: Diabetes and higher HbA1c level have increased the incidence of stroke. Hemoglobin levels both high and low are associated with poor outcomes. Leukocytes play an important role in the initiation of the atherosclerosis process.Methods: This was a cross-sectional study with a sample size of 62 people selected by non-random sampling method on a consecutive basis, patients with acute stroke were taken blood to measure blood glucose levels, HbA1c, Hb and Leucocytes when entering the hospital room. Outcomes were assessed using NIHSS and MRS. The calculation of NIHSS and MRS scores was performed on the first day of admission and the fourteenth day. To analyze the correlation of blood sugar levels during HbA1c, Hb and leukocytes in acute stroke, this study used Spearman's correlation test. The p value <0.05 was considered statistically significant.Results: The study subjects of 62 acute stroke patients (acute ischemic stroke 31 people and 31 people hemorrhagic stroke). Acute stroke patients were consisted of 38 men (61.3%) and 24 women (38.7%). Of 31 people with hemorrhagic stroke, there were 16 men (51.6%) and 15 women (48.4%), ischemic stroke patients were consisted of 22 people (71, 0%) and women were 9 people. Spearrman repair test showed no symptoms between blood glucose levels, HbA1c, Hemoglobin and leukocytes with outcomes in acute stroke.Conclusions: There was no significant association between blood glucose levels, HbA1c, hemoglobin and leukocytes with outcomes in acute stroke.


2019 ◽  
Vol 5 (2) ◽  
pp. 57
Author(s):  
Yesi Warisman ◽  
Arinda Lironika Suryana ◽  
Zora Olivia

Diabetes mellitus is a metabolic disease with special characteristic which increased blood glucose level (hiperglicemic), its happens because of the abnormality of insulin secretion, insulin mechanisme or both of them. Belimbing wuluh and red guava extract can become alternative functional drink that contain rich of vitamin C to help controlling blood glucose level. The aimed of this study was to determined the effect of belimbing wuluh and red guava extract on blood glucose levels of Rattus novergicus strain Wistar diabetic model. This research was an true experimental study with a randomized post-test control group design. Twentyfour (24) male wistar strain rats weighing 200-250 grams, aged 2-3 months, were divided into 4 groups. The control group (K-) non-diabetic rats, the control group (K+) diabetic rats given standard diet, and the treatment group diabetic rats given standard diet and belimbing wuluh and red guava extract intervetion doses 10,7 ml/day (P1) and 21ml/day (P2). Measurement of pretest posttest fasting blood glucose levels was carried out using biolyzer. The data were analyzed by One Way Anova test. The results showed that there were significant differences in delta pretest and posttest fasting blood glucose levels between all groups. Blood glucose levels decreased at 55.6%. In conclusion, belimbing wuluh and red guava extract 21ml/day most effectively decreased fasting blood glucose levels in diabetic wistar rats moldel.   Keywords: belimbing wuluh, blood glucose level, diabetes mellitus, red guava


2021 ◽  
Vol 15 (10) ◽  
pp. 2595-2596
Author(s):  
M. Asim Rana ◽  
Mujtaba H. Siddiqui ◽  
Sitara Raza ◽  
Kinza Tehreem ◽  
M. F.Ullah Mahmood ◽  
...  

Background: Since the COVID-19 pandemic has started, glucocorticoids have been proved to be one of the most effective lifesaving treatments for respiratory complications associated with SARS CoV-2. Aim: To review the incidence of steroid induced diabetes and the associated risk factors in COVID-19 patients. Study Design: Retrospective cohort study Place and duration of the study: Bahria International Hospital Lahore from 15th April 2020 to 31st December 2020 Methodology: Two hundred and thirty patients of COVID-19 cases treated with glucocorticoids (Dexamethasone 4mg BID) were enrolled. All known cases of pre-existing diabetes mellitus and with initial (admission) random blood glucose levels of more than 200 mg/dl were excluded. Patients labelled as glucocorticoid induced diabetes mellitus (GI-DM)met the following criteria, fasting blood glucose level of more than 126 mg/dl or a random glucose level of more than200 mg/dlon two occasions after starting these patients on steroids. Results: The glucocorticoid induced diabetes mellitus was 36 (15.65%). Multivariate logistic regression analysis revealed that older age (odds ratio 1.19, 95% confidence interval (1.02-1.36) was found to be the most profound risk factor for GI-DM. Conclusion: Glucocorticoid induced diabetes mellitus found to be associated with glucocorticoid used among COVID-19 patients especially in older ages. So, it is recommended that the treating physicians should consider this side effect of steroids especially when dealing with geriatric cases. Keywords: Hyperglycaemia, COVID-19, Steroids, SARS-CoV-2, Diabetes mellitus, Steroids induced diabetes, Glucocorticoids


2021 ◽  
Vol 17 (4) ◽  
pp. 194
Author(s):  
Rahma Wati Dwi Lestari ◽  
Deny Yudi Fitranti ◽  
Nurmasari Widyastuti ◽  
Ahmad Syauqy ◽  
Binar Panunggal ◽  
...  

Effect of diets with glycemic load arrangement on blood glucose levels in young soccer athletes Background: Carbohydrate arrangement considering the glycemic index (GI) and glycemic load (BG) are important to support the performance of athletes.Objective: To examine the effect of diets with glycemic load arrangement on blood glucose levels in young soccer athletes.Methods: Quasi-experimental study on 14 male young soccer players aged 15-18 years old at Terang Bangsa Soccer School. Each subject completed 4 trials separated by at least 7 days as a washout period. Diets provided consist of high GI with high GL diet (H-H), low GI with high GL diet (L-H), high GI with low GL (H-L), and low GI with low GL diet (L-L). Collected data were fasting blood glucose level (BGL 0), blood glucose level one hour after intervention (BGL 1), blood glucose level two hours after intervention (BGL 2), and blood glucose level after exercise (BGL 3).Results: The results of paired t-test analysis showed that there were differences between fasting blood glucose level and blood glucose level one hour after intervention, blood glucose level one hour after intervention and blood glucose level two hours after intervention, blood glucose level two hours after intervention and blood glucose level after exercise in the H-H and L-H diet group. In the L-L diet group, there were differences between BGL 2 and BGL 3. One-Way ANOVA analysis showed that there were no significant differences in blood glucose levels one hour after the intervention, blood glucose level two hours after intervention, and blood glucose level after exercise between groups.Conclusions: High glycemic load diets influence the increase in blood glucose levels at 1 hour postprandial and after exercise. Low glycemic load diets influence the increase in blood glucose levels after exercise. Diets with the arrangement of glycemic index and glycemic load did not affect blood glucose levels between diet groups. 


Sign in / Sign up

Export Citation Format

Share Document