KTP/532 YAG Laser Treatment for Allergic Rhinitis

2009 ◽  
Vol 23 (5) ◽  
pp. 527-530 ◽  
Author(s):  
Eitan Yaniv ◽  
Tuvia Hadar ◽  
Jacob Shvero ◽  
Rami Tamir ◽  
Ben Nageris
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Obstruction ◽  
Nasal Congestion ◽  
Additional Treatment ◽  
Skin Tests ◽  
Nasal Discharge ◽  
Office Procedure ◽  
Positive Skin ◽  
Yag Laser ◽  
Symptom Reports

Background The purpose of this study was to investigate the efficacy of the KTP/532 YAG laser to reduce nasal congestion and discharge in patients with allergic rhinitis. Methods Forty-eight patients with symptoms of allergic rhinitis were treated with the KTP/532 laser. All had positive skin tests for common allergens. Treatments were provided on an ambulatory basis in one to three sessions under local anesthesia with lidocaine nose spray. Outcome was determined by daily symptom reports and regular endoscopy examination and interviews for 12 months. Results Treatment was very well tolerated. There were no major side effects. At examination after 1 year, nasal obstruction was improved in 69% and nasal discharge in 40% of cases. Conclusion The KTP/532 YAG laser is effective for the treatment of nasal obstruction and discharge. Comparison with other techniques showed it to be the most effective in reducing nasal discharge. It can be done as an office procedure and does not damage the nasal mucous membrane. The KTP/532 YAG laser is effective as an additional treatment for patients refractory to medication.

scholarly journals Immunotherapy in Allergic Rhinitis: It’s Effect on the Immune System and Clinical Symptoms

2018 ◽  
Vol 6 (7) ◽  
pp. 1248-1252 ◽  
Author(s):  
Samaneh Kouzegaran ◽  
Mohammad Ali Zamani ◽  
Reza Faridhosseini ◽  
Houshang Rafatpanah ◽  
Abdolrahim Rezaee ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Symptoms ◽  
Nasal Congestion ◽  
Subcutaneous Immunotherapy ◽  
Positive Skin Prick Test ◽  
Tgf Beta ◽  
Positive Skin ◽  
Ifn Gamma ◽  
Clinical Criteria ◽  
Prick Test

BACKGROUND: Allergic rhinitis is one of the most common allergic diseases and characterised by sneezing, rhinorrhea, nasal congestion and nasopharyngeal itching. Subcutaneous immunotherapy (SCIT) for specific allergens is an effective treatment and induces the inhibitory effect of T regulatory lymphocytes and decreases clinical symptoms in allergic rhinitis.AIM: In this study effect of subcutaneous immunotherapy with specific allergens on clinical symptoms and T regulatory and T Helper cells cytokines, in patients with allergic rhinitis are evaluated.METHODS: In this study, 30 patients with moderate to severe allergic rhinitis according to clinical criteria and positive skin prick test for aeroallergens were selected and treated by SCIT. Clinical symptoms and T cells cytokines IL4, IL17, IFN gamma, TGF beta, GITR, FOXP3 and IL-10 (by RT-PCR) were evaluated before and one year after initiation of treatment.RESULTS: Thirty (30) patients with allergic rhinitis at age range 15-45 years old were treated by SCIT, and 23 (14 female, 9 male) patients continued the study, and 7 patients did not continue treatment. After immunotherapy, clinical symptoms decreased significantly. The specific cytokines TGF beta and IL10 levels increased and changes were statistically significant. (Respectively P = 0.013 and P = 0.05) The IL17 level was also increased, but not statistically significant. (P = 0.8) IFN gamma, IL4, GITR, FOXP3, all decreased, but the changes were not statistically significant (P > 0.05).CONCLUSION: Subcutaneous Immunotherapy for specific allergens decreases clinical symptoms in patients with allergic rhinitis and induces tolerance in T lymphocytes, especially by increasing T regulatory cells cytokines, TGF beta and IL10.

scholarly journals Role of mometasone furoate nasal spray in children with adenoid hypertrophy: impact on life style changes

2020 ◽  
Vol 6 (9) ◽  
pp. 1709
Author(s):  
Venkatesha B. K. ◽  
Ravi Shekhar
Keyword(s):  
Nasal Obstruction ◽  
Nasal Spray ◽  
Statistical Tests ◽  
Nasal Congestion ◽  
Sleep Apnea Syndrome ◽  
Mometasone Furoate ◽  
Nasal Discharge ◽  
Adenoid Hypertrophy ◽  
Obstructive Sleep ◽  
Life Style Changes

<p class="abstract"><strong>Background:</strong> Adenoid hypertrophy (AH) is a common cause of upper airway obstruction and obstructive sleep apnea syndrome (OSAS) in children having major impact on child’s growth and development. Symptoms like nasal congestion, mouth breathing, nasal discharge, snoring, day time sleepiness, hyponasal voice, ear popping, and craniofacial abnormalities are observed. Adenoidectomy is considered the treatment of choice for symptomatic children. Co-existing medical illnesses and choice of surgical treatment is governed by the paediatricians and apprehensive parents. Need for conservative treatments in alleviating symptoms have been tried. Topical, intranasal administered, steroid preparations have been proven effective in the literature.</p><p class="abstract"><strong>Methods:</strong> In this prospective study, 35 symptomatic children (3-12 years) with adenoid hypertrophy were included. Each of the symptoms was scored from 0 (absent) to 4 (severe) over Visual Analogue Scale (VAS). Nasal obstruction index was calculated. Results of mometasone furoate nasal spray 100 microgram/day used once daily at the interval of 8 weeks and 12 weeks were analysed using statistical tests.  </p><p class="abstract"><strong>Results:</strong> A statistically significant reduction in nasal obstruction index and other symptoms were noted at the end of third month follow up.</p><p class="abstract"><strong>Conclusions:</strong> Mometasone furoate nasal spray caused improvements in outcomes of nasal obstruction, snoring, total nasal symptoms, ear symptoms and overall quality of life.</p>

scholarly journals Correlation of Features of Allergic Rhinitis and Allergic Conjunctivitis with Treatment Modalities

2019 ◽  
pp. 1-10 ◽  
Author(s):  
Shuaib Kayode Aremu ◽  
Tayo Ibrahim ◽  
Azeez Oyemomi Ibrahim ◽  
Popoola Tomilayo Ajoke
Keyword(s):  
Allergic Rhinitis ◽  
Allergic Conjunctivitis ◽  
Nasal Congestion ◽  
Nasal Symptom ◽  
Treatment Modalities ◽  
Nasal Discharge ◽  
Southwestern Nigeria ◽  
Cross Sectional ◽  
Female Ratio ◽  
Eye Pain

Introduction: Allergic Rhinitis (AR) is a chronic, symptomatic allergic disorder of the nose that is usually caused by IgE-mediated inflammatory response following exposure to an allergen. The allergen could be in the form of dust, pollen, flower, animal dander, mold, cold, food allergens or insect. Clinically, AR occurs when there are recurrent nasal symptoms which are reversible either spontaneously or with medication in the preceding one year. Such symptoms include at least two of the following; excessive sneezing, running nose, nasal itching, nasal discharge, nasal congestion or obstruction. Previous studies have linked AR to be co-existed with another form of allergic disorders including AC, Atopic dermatitis and Allergic Asthma. This study is aimed at assessing the feature of  AR patients with coexistent AC as well as evaluating the effectiveness of the treatments offered to them. Objectives: The study was aimed at finding the correlation between the nasal and eye features in a patient who has co-existing allergic rhinitis and allergic conjunctivitis. Methodology: This was a cross-sectional descriptive study conducted between August 2018 and November 2019 among 38 patients who presented to ENT and Ophthalmology departments of Federal Teaching Hospital Ido-Ekiti, Ekiti State, Southwestern Nigeria and was diagnosed with both allergic rhinitis and allergic conjunctivitis. Relevant data obtained were analyzed using SPSS version 20.  P ≤ 0.05 was taken as significant. Results: The patients’ age range between 8 and 81 years with a median age of 33 years. The majority were less than 45 years (63.2%) with the male to female ratio of almost. Eye pain, itching, and redness account for 97.4% of all the eye features, while the presence of Cobblestone-like papillae is the least and accounted for 5%. Nasal itching (92.1%) was the commonest nasal symptom. Sleep disturbance was found to be the most common among those with eye itching (29.7%). Conclusion: This research was conducted to correlate the features of allergic rhinitis with those of conjunctivitis and common management and preventive measures offered to the patients seen in our clinics. The majority of the patients were less than 45 years with almost equal sex ratio. Eye pain, itching, and redness account for the majority of all the eye features, while the presence of Cobblestone-like papillae is the least eye feature. Nasal itching was the commonest nasal symptom and this was seen in the majority of the patients with eye symptoms.

scholarly journals GAMBARAN DERAJAT KEPARAHAN GEJALA PASIEN RINOSINUSITIS KRONIK DI RSUD DR. SOETOMO SURABAYA

2020 ◽  
Vol 8 (2) ◽  
pp. 235
Author(s):  
Anggita Putri Samara ◽  
Budi Sutikno ◽  
Reny I’tishom
Keyword(s):  
Risk Factor ◽  
Observational Study ◽  
Medical Record ◽  
Nasal Obstruction ◽  
Facial Pain ◽  
Nasal Congestion ◽  
The Other ◽  
Nasal Discharge ◽  
Analog Scale ◽  
Nasal Inflammation

Chronic rhinosinusitis (CRS) is a sinus paranasal and nasal inflammation marked with two or more symptoms, nasal congestion or nasal discharge and the other symptom like facial pain and reduced smell may present. This symptom occur >12 weeks. One of the parameter for symptom’s severity assessmentis using Visual Analog Scale (VAS) that can be classified as mild (0-3), moderate (4-7), dan severe (8-10). This study was a observational study by assessing patient’s medical record at SMF THT-KL RSUD Dr. Soetomo and analyzed descriptively. 43 patients were enrolled to study (28 male and 15 female), most of them were between age 36-45 years old (25,58%). Most of the patient’s symptom’s severity in general, nasal obstruction, nasal discharge, facial pain, and reduced smell were moderate (65,11%), moderate (58,13%), mild (41,86%), mild (58,13%), mild (62,79%) respectively. Most of the patients had risk factor (62,79%), and the most of the patient’s risk factor were allergy. Most of the CRS patients in this study were male, 36-45 years old, with the general symptom’s severity moderate, moderate nasal obstruction, mild nasal discharge, mild facial pain, mild reduced smell, and had allergy.

Effect of mometasone furoate nasal spray on moderate-to-severe nasal congestion in seasonal allergic rhinitis: A responder analysis

2019 ◽  
Vol 40 (3) ◽  
pp. 173-179 ◽  
Author(s):  
Eduardo Urdaneta ◽  
Kaan Tunceli ◽  
Davis Gates
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Spray ◽  
Seasonal Allergic Rhinitis ◽  
Nasal Congestion ◽  
Mometasone Furoate ◽  
Double Blind ◽  
Positive Skin ◽  
Once Daily ◽  
Responder Analysis ◽  
End Point

Background: Nasal congestion is consistently identified as the most bothersome symptom of seasonal allergic rhinitis (SAR), and, in guidelines, intranasal corticosteroids are the preferred treatment for nasal congestion. Objective: The aim of this post hoc cumulative responder analysis was to examine the nasal congestion response in detail by depicting the level of response obtained in two double-blind, placebo controlled studies of mometasone furoate nasal spray (MFNS) therapy for SAR, conducted from August to October 2008 at U.S. sites, in which nasal congestion was prespecified as the primary end point. Methods: Patients ≥12 years of age with a ≥2-year SAR history, positive skin test result, and moderate or severe nasal congestion were randomly assigned to once-daily treatment in the morning with MFNS or placebo for 15 days. The primary end point was the change from baseline in morning and evening reflective nasal congestion scores averaged over days 1‐15. Treatment response, which ranged from >0% to >90% improvement, was evaluated at 10% intervals; >30% and >50% improvements were further evaluated by using the Mietinnen-Nurminen method weighted by study to test the differences of proportions. The Breslow-Day equal odds ratios test was used to justify pooling. Results: Of the 344 and 340 patients in the MFNS and placebo groups, respectively, the proportions of patients who experienced a >30% response in nasal congestion, averaged over 15 days, were 37% versus 19% in the MFNS and placebo groups, respectively (p < 0.001). Those who experienced a >50% response were 13% and 7%, respectively (p = 0.003). Among the patients treated with MFNS, the mean response was greater during the second versus the first week of treatment. There was no difference between responses in the morning versus evening or for patients with moderate versus severe nasal congestion at baseline. Conclusion: MFNS is effective in relieving moderate-to-severe nasal congestion in patients with SAR. The response to MFNS is maintained with once-daily administration and improves with continuous use over 2 weeks.

Effect of Shadbindu Taila and Haridra Khanda in Pratishyaya (Allergic Rhinitis)

The Healer ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 58-60
Author(s):  
Sadhana Parajuli ◽  
Pramod Bhatta ◽  
D.L Bharkher
Keyword(s):  
Immune Response ◽  
Allergic Rhinitis ◽  
Nasal Mucosa ◽  
Significant Role ◽  
Vital Sign ◽  
Nasal Congestion ◽  
Combined Therapy ◽  
Nasal Discharge ◽  
Before And After ◽  
Airborne Allergens

Allergic rhinitis (AR) is an immune response of the nasal mucosa to airborne allergens and involves nasal congestion, watery nasal discharge, itching of the nose, and sneezing. Ayurveda describes Pratishyaya as one of the most important diseases among the 31 Nasarogas. Acharya Sushruta clearly mentioned that Pratishyaya is the condition in which vata kapha dusti was observed. Haridra Khanda is one of the prominent anti allergic drugs mentioned in ayurveda. Pratimarsha nasya has significant role in the prevention of urdhvajatrugata rogas. Ancient acharya has told to try shadbindu taila and Haridra khanda both locally and systematically in the management of pratishyaya. Here 30 patients were selected open randomly in shalakya opd of ayurveda campus kirtipur. They were given pratimarsha nasya with sadhbindu taila and internally haridra khanda for 30 days. The vital sign and symptom of pratishyaya like nasa srava, nasa kandu, kshavatu, nasa kandu and shira shula were studied before and after the treatment. The result of the study indicated that the combined therapy of internally Haridra Khanda and external pratimarsha narsha with sadbindu tail has given significant result in the treatment of Allergic Rhinitis (Pratishyaya).

scholarly journals The use of nasal decongestants to correction the respiratory and olfactory function of the nose

2019 ◽  
pp. 60-65 ◽  
Author(s):  
S. V. Morozova ◽  
L. A. Toporkova
Keyword(s):  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Paranasal Sinuses ◽  
Nasal Congestion ◽  
Olfactory Function ◽  
Nasal Discharge ◽  
Nasal Breathing ◽  
Nasal Decongestants ◽  
Osteomeatal Complex ◽  
Tube Dysfunction

One of the main functions of the nose is respiratory and olfactory. Difficulty in nasal breathing, nasal congestion, nasal discharge can complicate the respiratory and olfactory functions of the nose or make them impossible. Most often the cause is swelling of the mucous. Nasal obstruction and rhinorrhea are the most common symptoms in diseases of the nasal cavity and paranasal sinuses. Of great importance is the use of local vasoconstrictors to eliminate swelling in the nasal cavity and prevent complications associated with auditory tube dysfunction. It is proved that the use of nasal decongestants helps to reduce swelling in the nasal cavity and in the osteomeatal complex. Otrivin Moisturizing formula, Otrivin Menthol, Otrivin Complex and Otrivin Sea are effective and well tolerated means to eliminate swelling in the nasal cavity and reduce nasal discharge and rehabilitation of olfactory function.

Chemosurgery with Trichloroacetic Acid for Allergic Rhinitis

1995 ◽  
Vol 9 (3) ◽  
pp. 163-168 ◽  
Author(s):  
Kazuo Yao ◽  
Tetsuya Shitara ◽  
Hiro-omi Takahashi ◽  
Kouichiro Nishiyama ◽  
Yoshiaki Iguchi ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Side Effects ◽  
Nasal Obstruction ◽  
Trichloroacetic Acid ◽  
Nasal Discharge ◽  
Perennial Allergic Rhinitis ◽  
Nasal Wash ◽  
Histamine Concentration ◽  
Histological Studies ◽  
Provocation Tests

The use of 80 w/v% solution of trichloroacetic acid (TCA) for the treatment of allergic rhinitis was reported. The solution was applied to the inferior turbinates only once bilaterally. The result of the treatment in 77 nonselected cases of perennial allergic rhinitis for over 3 years showed that an improvement was obtained in 72% for nasal obstruction, 60% for sneezing, and 50% for watery nasal discharge. The result of provocation tests after treatment showed an improvement in 77% of the cases, and the histamine concentration in the nasal wash decreased. These results were discussed with reference to the result of our previous histological studies. We concluded that our method of treatment using TCA was simple and effective for allergic rhinitis without any serious side effects.

scholarly journals Rhinomanometry: point of care test (POCT) for allergic rhinitis in children?

2021 ◽  
Vol 49 (5) ◽  
pp. 28-31
Author(s):  
Velia Malizia ◽  
Guiliana Ferrante ◽  
Giovanna Cilluffo ◽  
Salvatore Fasola ◽  
Laura Montalbano ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Obstruction ◽  
Immunoglobulin E ◽  
Point Of Care ◽  
Anterior Part ◽  
Clinical History ◽  
Objective Evaluation ◽  
Diagnostic Techniques ◽  
Skin Tests ◽  
Potential Use

Allergic rhinitis (AR) is a global health problem: its prevalence is 23% in Europe, although it is underestimated because as many as 45% of the cases remain undiagnosed. Globally, almost 500 million people suffer from AR, which shows its increasing incidences. The diagnostic course of AR is based on clinical history, supported by anterior rhinoscopy. This inspects the anterior part of the nasal cavity accompanied by allergic sensitivity tests (cutaneous allergic skin tests or specific immunoglobulin E levels). The availability of standardised diagnostic proceduresis able to provide objective evaluations of inflammatory situation, and the degree of nasal obstruction may give an advantage in reducing the risk of underestimating the diagnosis of AR. Diagnostic tests with a high level of accuracy are able to provide immediate results, which can sustain the doctor in diagnostic–therapeutic framework. The development of Point of Care Tests (POCTs) could be a useful tool. Considering that nasal obstruction is the mostcommon symptom in patients with AR, the rhinomanometry (RM) test is the most indicated objective evaluation for nasal obstruction. Several studies have also shown the practicability of such diagnostic techniques applied in children. So far, no study has evaluated whether all the applicable requirements are fulfilled by RM in order to be considered as a POCT. The purpose of this perspective was to assess whether all the POCT requirements are fulfilled by RM by conducting a narrative review of the existing literature in which RM has been used in the diagnosis and management of AR in children. A few but encouraging results of studies on children supported the potential use of RM in the area of POCT. However, costs of instruments and the training of personnel involved remain to be explored. The studies support the potential use of RM in POCTs.

PEDIATRIC ALLERGY: SOME IMPRESSIONS GAINED OVER A 37-YEAR PERIOD

PEDIATRICS ◽  
1971 ◽  
Vol 48 (6) ◽  
pp. 930-938
Author(s):  
William C. Deamer
Keyword(s):  
Allergic Rhinitis ◽  
Respiratory Tract ◽  
Parasympathetic Nervous System ◽  
Clinical Symptoms ◽  
Skin Tests ◽  
Positive Skin ◽  
Effective Measure ◽  
History Of ◽  
Tract Infections ◽  
Inhalant Allergy

The most effective treatment of allergy is discovery and removal of the allergen. Injection therapy, while useful in some forms of inhalant allergy such as hay fever, is a less effective measure. Respiratory tract allergy is frequently mistaken for respiratory tract infection. A history of repeated episodes of bronchitis or pneumonia should suggest the possibility of asthma. Similarly, a history of repeated "colds" should suggest allergic rhinitis. Increased sneezing and itching and rubbing of the nose are frequent minor symptoms of allergic rhinitis. Coughing at night and coughing on exertion are common minor symptoms of asthma. Since allergic rhinitis and asthma often occur together and share the same etiology, all four of these minor symptoms may serve as a guide in identifying and treating asthma. Positive skin tests for allergy may be found in as much as 50% of "normal" individuals, many of whom may have no recognized clinical allergy. Positive skin tests therefore do not constitute evidence of clinical symptoms. Nonspecific trigger factors such as nervous tension, respiratory tract infections, fatigue, climate, exercise, and smoke or strong odors may precipitate an attack of asthma. Frequently overlooked are the more important specific factors such as pollens, house dust, animal danders, and foods. An important variable factor in asthma is the state of the patient's sympathetic-parasympathetic nervous system balance. At times this may act to augment synergistically the action of the chemical mediators of the allergic reaction, thus involving non-immunological as well as immunological factors. Food allergy or intolerance is a frequently unrecognized cause of asthma and allergic rhinitis. It is also a frequent cause of the tension-fatigue syndrome–a common but little known entity.

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