scholarly journals PHYSIOLOGICAL PREDICTORS OF LONG-TERM EFFECTS OF COVID-19 IN PATIENTS WITH SARS-COV-2: FOCUS ON LYMPHOCYTE PROLIFERATION-IMPROVING MICRONUTRIENTS

2021 ◽  
Vol 65 (2) ◽  
Author(s):  
Sofia-Maria Karkhut ◽  
◽  
Iryna Muzyka ◽  
Maryana Savytska ◽  
Khrystyna Dzhyoieva ◽  
...  
Keyword(s):  
Lymphocyte Proliferation ◽  
Metabolic Health ◽  
Long Term Effects ◽  
Human Immune System ◽  
Adaptive Immune ◽  
Human Immune ◽  
Iron Manganese ◽  
The Impact ◽  
The Relationship

Patients with long-term effects of coronavirus disease, the so-called “long-term COVID-19 syndrome” (long-COVID-19) after SARS-CoV-2 infection, have a postponed recovery lasting from 4 weeks and up to six months, spread worldwide. Physiological predictors based on human blood biomarkers and host-virus responses to SARS-CoV-2 are still unknown. There is growing evidence about the impact of micronutrients on improving lymphocyte proliferation and their essential roles for a functioning human immune system and regulating metabolic health. This paper aims to review information about micronutrients in patients with SARS-CoV-2 infection that determines long-COVID-19 outcomes and highlight the importance of diagnostics in predictors of long-COVID-19. We reviewed articles returned from searches on PubMed/SCOPUS/Web of Science/ EMBASE databases using a combination of terms “long COVID-19”, “long-term effects of COVID-19”, “post-COVID-19 symptoms”, “COVID-19 associated stress”, “micronutrients”. Evidence indicates the relationship between lymphocyte proliferation improving micronutrient level and long-COVID-19 induction. Zinc, selenium, iron, manganese have an immunomodulatory function in innate and adaptive immune responses to viral infection. Anti-inflammatory functions of Vits A and B groups include the regulation of lymphocyte proliferation and metabolic health. Further research using sampling and artificial intelligence-assisted algorithms could assist in the recognition of the correlation of micronutrients and long-COVID-19 clinical outcomes

Terrorism and tourism in Israel

2016 ◽  
Vol 23 (6) ◽  
pp. 1343-1352 ◽  
Author(s):  
Marion Karl ◽  
Gordon Winder ◽  
Alexander Bauer
Keyword(s):  
Time Lag ◽  
Research Model ◽  
Long Term Effects ◽  
Short Term ◽  
Event Tourism ◽  
Using Data ◽  
Terrorist Event ◽  
The Impact ◽  
The Relationship

While the relation between terrorism and tourism has been an important topic for tourism research, the questions whether terrorism affects tourism immediately and how long after a terrorism event tourism recovers are, as yet, not clearly answered. The aim of this article is to better understand the magnitude and temporal scale of the impact of terrorism on tourism. To this end, a research model differentiating between short-term and long-term effects of terrorism on tourism is developed and analyzed for the destination Israel using data on tourists from Germany. The results show both short-term and long-term impacts with a time lag between the terrorist event and the beginning of tourism decline of 1 or up to 6 months. An economic influence on the development of tourist arrivals was not detected, but seasonality plays an important role in the relationship between terrorism and tourism.

scholarly journals Benevolent Ageism: Exploring Its Boundary Conditions, Generalizability, and Correlates

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 568-569
Author(s):  
Toni Bisconti ◽  
Jennifer Sublett ◽  
Alison Chasteen
Keyword(s):  
Older Adults ◽  
Boundary Conditions ◽  
Cognitive Outcomes ◽  
Long Term Effects ◽  
Chinese Sample ◽  
Self Compassion ◽  
Stereotype Content ◽  
The Impact ◽  
The Relationship

Abstract Ageism is one of the few prejudices that is still socially condoned (Nelson, 2016). Given the aging population and the impact of internalizing ageist thoughts, this construct needs to be at the forefront for scientific examination. The long-term effects of ageism, particularly negative self-perceptions, lead to negative health and cognitive outcomes (Chasteen et al., 2015; Levy et al., 2002). One of the intricate components of ageism, however, is that it is often “benevolent”. Cuddy and colleagues developed the Stereotype Content Model (SCM) to describe how individuals are categorized based on varying degrees of warmth and competence. Unlike many devalued members of society who are viewed as low on both, older adults are viewed as having high warmth and low competence, leading to more overaccommodative treatment. The goal of the present symposium is to overview the ways in which researchers have dissected this more nuanced type of ageism. Specifically, two of the presenters will cover some of the boundary conditions of understanding age-based stereotypes and their malleability, examining them across ages and across genders. Additionally, one of our presenters will overview the validation of the Ambivalent Ageism Scale on a Chinese sample, lending support to its generalizability. Finally, our last presenter will overview the relationship between benevolent ageism and self-compassion to predict metamemory, given the pervasive stereotype that older adults suffer from severe cognitive decline. Themes and implications of these presentations will be discussed.

scholarly journals Mecanismos de la respuesta inmune adaptativa: respuesta específica y de protección a largo plazo

2020 ◽  
Vol 3 (8) ◽  
pp. 25-43
Author(s):  
William de Jesús Ríos-Ríos ◽  
Jair Aguilar-Cruz
Keyword(s):  
Immune Response ◽  
Immune System ◽  
Adaptive Immune Response ◽  
Molecular Structures ◽  
Pathogenic Microorganism ◽  
Human Immune System ◽  
Adaptive Immune ◽  
Specific Immunity ◽  
Human Immune

The human immune system has evolvedtoachieveahighlyefficient, specialized and specific immunity against particular molecular structures of each pathogenic microorganism and to develop mechanisms allowing to respond more quickly and efficiently to subsequent encounters with the same invading agent: the adaptive immune response. This paper describes the connection between the innate and adaptive immune response, as well as the cellular and humoral mechanisms of control and long-term protection of the adaptive immune response.

scholarly journals Will SARS-CoV-2 Infection Elicit Long-Lasting Protective or Sterilising Immunity? Implications for Vaccine Strategies (2020)

2020 ◽  
Vol 11 ◽  
Author(s):  
David S. Kim ◽  
Sarah Rowland-Jones ◽  
Ester Gea-Mallorquí
Keyword(s):  
Immune Response ◽  
Protective Immunity ◽  
Vaccine Development ◽  
Adaptive Immune Response ◽  
Human Immune System ◽  
Adaptive Immune ◽  
Global Pandemic ◽  
Human Immune ◽  
Novel Coronavirus

In December 2019, an outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China resulted in the current COVID-19 global pandemic. The human immune system has not previously encountered this virus, raising the important question as to whether or not protective immunity is generated by infection. Growing evidence suggests that protective immunity can indeed be acquired post-infection—although a handful of reinfection cases have been reported. However, it is still unknown whether the immune response to SARS-CoV-2 leads to some degree of long-lasting protection against the disease or the infection. This review draws insights from previous knowledge regarding the nature and longevity of immunity to the related virus, SARS-CoV, to fill the gaps in our understanding of the immune response to SARS-CoV-2. Deciphering the immunological characteristics that give rise to protective immunity against SARS-CoV-2 is critical to guiding vaccine development and also predicting the course of the pandemic. Here we discuss the recent evidence that characterises the adaptive immune response against SARS-CoV-2 and its potential implications for the generation of memory responses and long-term protection.

The impact of gelotophobia, gelotophilia and katagelasticism on creativity

2013 ◽  
Vol 26 (4) ◽  
Author(s):  
Yu-Chen Chan ◽  
Hsueh-Chih Chen ◽  
Joseph Lavallee
Keyword(s):  
Positive Association ◽  
Negative Influence ◽  
Creative Performance ◽  
Long Term Effects ◽  
Short Term ◽  
Creative Behavior ◽  
Broaden And Build Theory ◽  
The Impact ◽  
The Relationship

AbstractA number of studies have found that humor has a positive short-term effect in terms of enhancing creativity, but few have examined its long-term effects, and few have considered different personality traits when exploring this connection. The present study seeks to address this gap by examining the relationship between creativity and dispositions towards ridicule and being laughed at. We conceptualized humor-induced mirth as a positive emotion within the framework of broaden-and-build theory (Fredrickson 1998), with the potential to foster an individual's disposition towards creative behavior. We hypothesized that this potential would depend on different dispositions towards ridicule and being laughed at. Path analysis was then used to explore the impact of gelotophobia, gelotophilia and katagelasticism on creative performance, with creative disposition as a mediating variable. Gelotophobia, the fear of being laughed at, was found to correlate negatively with creative disposition, and may also exert an indirect negative influence on creative performance through its association with creative disposition. Gelotophilia, the joy of being laughed at, on the other hand, appears to have a partially mediated influence on creativity, exhibiting both a direct and an indirect positive relation through its positive association with creative disposition. No significant relation was observed between katagelasticism (the joy of laughing at others) and creativity.

Risk Attitude and Corporate Investment under Output Market Uncertainty: Evidence from The Mekong River Delta, Vietnam

2016 ◽  
pp. 59-70
Author(s):  
Ninh Le Khuong ◽  
Nghiem Le Tan ◽  
Tho Huynh Huu
Keyword(s):  
Negative Relationship ◽  
Risk Attitude ◽  
Business Strategies ◽  
Risk Averse ◽  
Market Uncertainty ◽  
Firm Investment ◽  
Output Market ◽  
The Impact ◽  
The Relationship

This paper aims to detect the impact of firm managers’ risk attitude on the relationship between the degree of output market uncertainty and firm investment. The findings show that there is a negative relationship between these two aspects for risk-averse managers while there is a positive relationship for risk-loving ones, since they have different utility functions. Based on the findings, this paper proposes recommendations for firm managers to take into account when making investment decisions and long-term business strategies as well.

SUMBER-SUMBER RESILIENSI PADA REMAJA AKHIR YANG MENGALAMI KEKERASAN DARI ORANGTUA PADA MASA KANAK-KANAK

Psibernetika ◽  
2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Devina Calista ◽  
Garvin Garvin
Keyword(s):  
Late Adolescents ◽  
Long Term Effects ◽  
Short Term ◽  
Parental Affection ◽  
Resilience Factors ◽  
Childhood Violence ◽  
Past Experiences ◽  
The Impact ◽  
Depth Interviews

<p><em>Child abuse by parents is common in households. The impact of violence on children will bring short-term effects and long-term effects that can be attributed to their various emotional, behavioral and social problems in the future; especially in late adolescence that will enter adulthood. Resilience factors increase the likelihood that adolescents who are victims of childhood violence recover from their past experiences</em><em>,</em><em> become more powerful individuals and have a better life. The purpose of this study was to determine the source of resilience in late adolescents who experienced violence from parents in their childhood. This research uses qualitative research methods with in-depth interviews as a method of data collection. The result shows that the three research participants have the aspects of "I Have", "I Am", and "I Can"; a participant has "I Can" aspects as a source of resilience, and one other subject has no source of resilience. The study concluded that parental affection and acceptance of the past experience have role to the three sources of resilience (I Have, I Am, and I Can)</em></p><p><em> </em></p><p><strong><em>Keyword : </em></strong><em>Resilience, adolescence, violence, parents</em></p>

The Quantification of Structural Reforms in OECD Countries

2018 ◽  
Author(s):  
Balázs Égert ◽  
Peter Gal
Keyword(s):  
Product Market ◽  
Physical Capital ◽  
Oecd Countries ◽  
Market Regulation ◽  
Structural Reforms ◽  
Long Term Effects ◽  
Per Capita ◽  
Product Market Regulation ◽  
The Impact

This chapter describes and discusses a new supply-side framework that quantifies the impact of structural reforms on per capita income in OECD countries. It presents the overall macroeconomic impacts of reforms by aggregating over the effects on physical capital, employment, and productivity through a production function. On the basis of reforms defined as observed changes in policies, the chapter finds that product market regulation has the largest overall single policy impact five years after the reforms. But the combined impact of all labour market policies is considerably larger than that of product market regulation. The paper also shows that policy impacts can differ at different horizons. The overall long-term effects on GDP per capita of policies transiting through capital deepening can be considerably larger than the five- to ten-year impacts. By contrast, the long-term impact of policies coming only via the employment rate channel materializes at a shorter horizon.

scholarly journals Antibiotics at birth and later antibiotic courses: effects on gut microbiota

2021 ◽  
Author(s):  
Sofia Ainonen ◽  
Mysore V Tejesvi ◽  
Md. Rayhan Mahmud ◽  
Niko Paalanne ◽  
Tytti Pokka ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Control Group ◽  
List Type ◽  
Antibiotic Exposure ◽  
Microbiota Composition ◽  
Long Term Effects ◽  
The Impact ◽  
Antibiotic Courses ◽  
Gut Microbiota Composition

Abstract Background Intrapartum antibiotic prophylaxis (IAP) is widely used, but the evidence of the long-term effects on the gut microbiota and subsequent health of children is limited. Here, we compared the impacts of perinatal antibiotic exposure and later courses of antibiotic courses on gut microbiota. Methods This was a prospective, controlled cohort study among 100 vaginally delivered infants with different perinatal antibiotic exposures: control (27), IAP (27), postnatal antibiotics (24), and IAP and postnatal antibiotics (22). At 1 year of age, we performed next-generation sequencing of the bacterial 16S ribosomal RNA gene of fecal samples. Results Exposure to the perinatal antibiotics had a clear impact on the gut microbiota. The abundance of the Bacteroidetes phylum was significantly higher in the control group, whereas the relative abundance of Escherichia coli was significantly lower in the control group. The impact of the perinatal antibiotics on the gut microbiota composition was greater than exposure to later courses of antibiotics (28% of participants). Conclusions Perinatal antibiotic exposure had a marked impact on the gut microbiota at the age of 1 year. The timing of the antibiotic exposure appears to be the critical factor for the changes observed in the gut microbiota. Impact Infants are commonly exposed to IAP and postnatal antibiotics, and later to courses of antibiotics during the first year of life. Perinatal antibiotics have been associated with an altered gut microbiota during the first months of life, whereas the evidence regarding the long-term impact is more limited. Perinatal antibiotic exposure had a marked impact on the infant’s gut microbiota at 1 year of age. Impact of the perinatal antibiotics on the gut microbiota composition was greater than that of the later courses of antibiotics at the age of 1 year.

scholarly journals Environmental Management, Green Innovation, and Social–Open Innovation

2021 ◽  
Vol 7 (1) ◽  
pp. 89
Author(s):  
Pham Thu Huong ◽  
Jacob Cherian ◽  
Nguyen Thi Hien ◽  
Muhammad Safdar Sial ◽  
Sarminah Samad ◽  
...  
Keyword(s):  
Environmental Management ◽  
Stock Exchange ◽  
Advanced Technology ◽  
Green Innovation ◽  
Social Image ◽  
Whole Process ◽  
Corporate Environmental Management ◽  
The Impact ◽  
The Relationship

The present study aims to determine the impact of green innovation (GI) on the overall performance of an organization while keeping the variable of environmental management (EM) as a moderator. We used a dataset consisting of four data years, from 2014 to 2017, of A-share companies listed on the Shanghai Stock Exchange (SSE). The concept of green innovation refers to the use of advancements in technology that enable savings in energy, along with the recycling of waste material. When advanced technology is utilized in the production process, the products are referred to as green products and the whole process of adopting such technologies and product design is referred to as “Corporate Environmental Management”. Such innovations improve the overall financial performance of companies as it enables them to improve their social image by reducing their carbon footprint and ensures their long-term sustainability. The main issue is the limited focus and attention given to the topic, from the perspective of companies. This research focuses on the impact of green innovation and the importance of environmental management for the sustainability of companies. Our findings suggest that the relationship between green innovation and the performance of the company is positive and verifies the existence of moderating effects of environmental management on the relationship between green innovation and firm performance. Implications are given to academia and practitioners.

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