scholarly journals Tuberculosis and pulmonary candidiasis co-infection present in a previously healthy patient

2016 ◽  
pp. 105-108 ◽  
Author(s):  
Dilia Mildret Fontalvo ◽  
Gustavo Jiménez Borré ◽  
Doris Gómez Camargo ◽  
Neylor Chalavé Jiménez ◽  
Javier Bellido Rodríguez ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Candida Albicans ◽  
Fungal Pathogens ◽  
Left Lung ◽  
Immunocompetent Patient ◽  
Clinical Findings ◽  
Massive Hemoptysis ◽  
Fungal Culture ◽  
Fungal Treatment ◽  
Immunocompetent Patients

Background: The coexistance among fungal pathogens and tuberculosis pulmonary is a clinical condition that generally occurs in immunosuppressive patients, however, immunocompetent patients may have this condition less frequently. Objective: We report the case of an immunocompetent patient diagnosed with coinfection Mycobacterium tuberculosis and Candida albicans. Case Description: 22-year-old female patient, previously healthy, who presented an episode of cough, massive hemoptysis and fever. Clinical findings and diagnosis: Physical examination was found crakles in left lung. Microbiological testing includes Ziehl Neelsen, culture for mycobacterium, fungal culture in Sabouraud Dextrose Agar medium and serum filamentation. The tests showed Mycobacterium tuberculosis and Candida albicans. Imaging studies included chest radiography, chest CT scan apicograma and high resolution supported the diagnosis. Treatment and Outcome: The patient was treated with anti-tuberculosis and anti-fungal treatment with good clinical evolution. Clinical relevance: Fungal infection and pulmonary tuberculosis is rare in immunocompetent patients should be suspected in abrupt episodes of hemoptysis.

scholarly journals Rare misdiagnosed case of penicilliosis marneffei in an immunocompetent patient

2020 ◽  
Vol 48 (10) ◽  
pp. 030006052095948
Author(s):  
Dan Cheng ◽  
Xuhong Ding
Keyword(s):  
Early Stage ◽  
Left Lung ◽  
Immunocompetent Patient ◽  
Pathological Examination ◽  
Fungal Culture ◽  
Tumor Treatment ◽  
Fungal Treatment ◽  
Case Presentation ◽  
Penicilliosis Marneffei ◽  
Anti Fungal

Background Penicilliosis marneffei is a rare disease caused by Talaromyces marneffei, which is endemic in Southeast Asian countries, and usually occurs in immunocompromised or immunodeficient hosts. We report an unusual misdiagnosed case of penicilliosis marneffei in an immunocompetent patient from a non-endemic area of China. Case presentation: A 59-year-old man presented to hospital with a cough and progressive hemoptysis for a 3-month period. Clinical characteristics, radiological abnormalities, and prognosis were analyzed. Detailed examinations, chest computed tomography, and bronchoscopy were performed. The patient was misdiagnosed as having lung cancer and provided anti-tumor treatment for 1 month in the early stage. Imaging and bronchoscopy showed a neoplasm in the basal segment in the left lung, but a tissue biopsy did not establish a diagnosis. He subsequently underwent lobectomy for the lesion. The final pathological diagnosis was penicilliosis marneffei based on immunohistochemical staining. He was then prescribed specific anti-fungal treatment of voriconazole 200 mg twice daily for 12 weeks. Conclusion Timely fungal culture and pathological examination of clinical specimens are critical for the diagnosis of penicilliosis marneffei, especially in non-endemic regions and immunocompetent patients.

scholarly journals Prostatic tuberculosis: case report

2008 ◽  
Vol 126 (4) ◽  
pp. 227-228 ◽  
Author(s):  
Daniel Sáenz-Abad ◽  
Santiago Letona-Carbajo ◽  
José Luis de Benito-Arévalo ◽  
Isabel Sanioaquín-Conde ◽  
Francisco José Ruiz-Ruiz
Keyword(s):  
Computed Tomography ◽  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Urine Culture ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Tuberculosis Case ◽  
Immunocompetent Patients

CONTEXT: Tuberculosis of the prostate has mainly been described in immunocompromised patients. However, it can exceptionally be found as an isolated lesion in immunocompetent patients. CASE REPORT: We report a case of prostatic tuberculosis in a young, healthy and immunocompetent patient with unremarkable findings from intravenous urographic examination. Computed tomography showed an abscess in the prostate and Mycobacterium tuberculosis was isolated in a urine culture. Treatment with isoniazid, rifampin and pyrazinamide was successful.

Pulmonary mucormycosis in immunocompetent hosts diagnosed by bronchioalveolar lavage

2021 ◽  
Vol 14 (4) ◽  
pp. e240180
Author(s):  
Sunil Kumar ◽  
Divya Joshi
Keyword(s):  
Gold Standard ◽  
Immunocompetent Patient ◽  
Fungal Culture ◽  
Radiological Imaging ◽  
Imaging Studies ◽  
Pulmonary Mucormycosis ◽  
Histopathological Evaluation ◽  
Patients With Diabetes ◽  
Symptoms And Signs ◽  
Immunocompetent Patients

Mucormycosis is a rare infection caused by Mucorales fungi belonging to Zygomycetes class. It can present with spectrum of symptoms and signs based of organ involvement. Common forms of mucormycosis includes rhinocerebral, cutaneous, gastrointestinal, pulmonary, disseminated and miscellaneous forms involving bones, breast, kidney and central nervous system. Pulmonary mucormycosis usually present with fever, cough, haemoptysis and is usually seen in immunocompromised patients like patients with diabetes or leukaemia, or those on chemotherapy or immunosuppressive therapy and rare in immunocompetent patients (6.25% of cases). Pulmonary mucormycosis can be diagnosed by radiological imaging studies, bronchoalveolar lavage (BAL) and histopathological evaluation of biopsy of the lesion; however, the gold standard is a positive fungal culture. Here, we describe two cases of pulmonary mucormycosis diagnosed by BAL in an immunocompetent patient.

Disseminated TB in an Immunocompetent Patient: A Case Report

2020 ◽  
Vol 20 ◽  
Author(s):  
Malihe Hassan Nezhad ◽  
Alireza Ganadan ◽  
Seyed Ahmad Seyed Alinaghi ◽  
Fatemeh Nili Ahmad Abadi ◽  
Seyed Ali Dehghan Manshadi ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Weight Loss ◽  
Mycobacterium Tuberculosis ◽  
Abdominal Pain ◽  
Case Report ◽  
Immunocompetent Patient ◽  
Seborrheic Keratosis ◽  
Prolonged Fever ◽  
Immunocompetent Patients

: Tuberculosis considered as a chronic infectious disease caused by Mycobacterium tuberculosis, may invade all organs but mainly affects the lungs [1].In overall, disseminated TB is rare in immunocompetent patients and its association with seborrheic keratosis has never been reported. We reported a54-year-old man with a complaint prolonged fever, abdominal pain, weight loss and lymphadenopathy without any immunosuppression who was eventually treated based on the diagnosis of diffuse tuberculosis.

scholarly journals Isolated Mycobacterium Tuberculosis Tenosynovitis and Osteomyelitis of the Foot in an Immunocompetent Patient

2021 ◽  
Vol 8 (6) ◽  
Author(s):  
Elgazzar A ◽  
◽  
Cecchini A ◽  
Elmezayen RI ◽  
◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Delayed Diagnosis ◽  
Pulmonary Involvement ◽  
Immunocompetent Patient ◽  
Complete Healing ◽  
Radiological Findings ◽  
Intravenous Antibiotics ◽  
Healing Wounds ◽  
High Index Of Suspicion ◽  
Immunocompetent Patients

Tubercular osteomyelitis must be considered in the differential diagnosis of immunocompetent patients who present with non-healing wounds with underlying osteomyelitis. Clinical and radiological findings may be indistinguishable from typical bacteria osteomyelitis. A high index of suspicion may prevent delayed diagnosis, and early treatment may prevent subsequent complications. This is a case report of an immunocompetent patient who presented with a chronic non-healing foot wound complicated by abscess and osteomyelitis that did not improve with an appropriate course of intravenous antibiotics. Wound cultures subsequently grew Mycobacterium tuberculosis without evidence of pulmonary involvement. The patient was treated with an initial two-month regimen of rifampin, isoniazid, pyridoxine, pyrazinamide and ethambutol, followed by a tenmonth regimen of rifampin, isoniazid and pyridoxine. The patient experienced significant improvement and complete healing of the foot wound after approximately the first two months of therapy.

Candida albicans endocarditis involving a normal native aortic valve in an immunocompetent patient

2020 ◽  
Vol 13 (11) ◽  
pp. e236902
Author(s):  
Taha Sheikh ◽  
Jeremy C Tomcho ◽  
Mohammed T Awad ◽  
Syeda Ramsha Zaidi
Keyword(s):  
Candida Albicans ◽  
Mortality Rate ◽  
Aortic Valve ◽  
High Mortality ◽  
Treatment Options ◽  
Immunocompetent Patient ◽  
Fungal Endocarditis ◽  
Appropriate Treatment ◽  
Mechanical Valves ◽  
Serious Infection

Fungal endocarditis, specifically from Candida species, is a rare but serious infection with a high mortality rate. Most cases occur in bioprosthetic or mechanical valves and are uncommon in native, structurally normal valves. When Candida endocarditis is detected and appropriate treatment is initiated earlier, there is an improvement in mortality. While the recommendation is usually to treat with a combination of surgery and antifungal medications, patient comorbidities may limit treatment options.

scholarly journals Septic shock due to Yersinia pseudotuberculosis infection in an adult immunocompetent patient: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Takehiro Hashimoto ◽  
Ryuichi Takenaka ◽  
Haruka Fukuda ◽  
Kazuhiko Hashinaga ◽  
Shin-ichi Nureki ◽  
...  
Keyword(s):  
Septic Shock ◽  
Therapeutic Strategy ◽  
Yersinia Pseudotuberculosis ◽  
Immunocompromised Host ◽  
Immunocompetent Patient ◽  
Case Presentation ◽  
Gram Negative ◽  
Old Japanese ◽  
The Right ◽  
Immunocompetent Patients

Abstract Background Yersinia pseudotuberculosis infection can occur in an immunocompromised host. Although rare, bacteremia due to Y. pseudotuberculosis may also occur in immunocompetent hosts. The prognosis and therapeutic strategy, especially for immunocompetent patients with Y. pseudotuberculosis bacteremia, however, remains unknown. Case presentation A 38-year-old Japanese man with a mood disorder presented to our hospital with fever and diarrhea. Chest computed tomography revealed consolidation in the right upper lobe with air bronchograms. He was diagnosed with pneumonia, and treatment with intravenous ceftriaxone and azithromycin was initiated. The ceftriaxone was replaced with doripenem and the azithromycin was discontinued following the detection of Gram-negative rod bacteria in 2 sets of blood culture tests. The isolated Gram-negative rod bacteria were confirmed to be Y. pseudotuberculosis. Thereafter, he developed septic shock. Doripenem was switched to cefmetazole, which was continued for 14 days. He recovered without relapse. Conclusions We herein report a case of septic shock due to Y. pseudotuberculosis infection in an adult immunocompetent patient. The appropriate microorganism tests and antibiotic therapy are necessary to treat patients with Y. pseudotuberculosis bacteremia.

MYCOBACTERIUM TUBERCULOSIS AND CANDIDA ALBICANS: A STUDY OF GROWTH-PROMOTING FACTORS

1954 ◽  
Vol 1 (2) ◽  
pp. 85-89 ◽  
Author(s):  
Edith Mankiewicz
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Candida Albicans ◽  
Growth Factor ◽  
Culture Media ◽  
Multiplication Rate ◽  
Pathological Specimen ◽  
Growth Promoting ◽  
Antibiotic Agents

A new growth factor for Mycobacterium tuberculosis is described. It is produced by Candida albicans and stimulates the growth of tubercle bacilli of reduced viability or multiplication rate, as this is observed after treatment of the patient by chemotherapeutic or antibiotic agents. A method for the earlier detection of M. tuberculosis growing on Loewenstein's medium is described: Loewenstein's culture media, previously inoculated with the pathological specimen suspected to contain tubercle bacilli, are superinoculated with suspensions of Candida albicans whose dependence upon the presence of tubercle bacilli to grow on this medium has been enhanced. Colonies of Candida albicans will "trace" the presence of M. tuberculosis.

Candida albicans diskitis after body piercing in an immunocompetent patient

2013 ◽  
Vol 80 (2) ◽  
pp. 226-227
Author(s):  
Christelle Darrieutort-Laffite ◽  
Claire Lassalle ◽  
Frédérque Chouet-Girard ◽  
Lucia Perez ◽  
Emmanuelle Dernis
Keyword(s):  
Candida Albicans ◽  
Immunocompetent Patient ◽  
Body Piercing
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