scholarly journals Factors of Inflammation in Haitian Americans and African Americans with and without Type 2 Diabetes

2014 ◽  
Author(s):  
Janet Antwi
2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Fatma G. Huffman ◽  
Maurcio De La Cera ◽  
Joan A. Vaccaro ◽  
Gustavo G. Zarini ◽  
Joel Exebio ◽  
...  

Ethnicities within Black populations have not been distinguished in most nutrition studies. We sought to examine dietary differences between African Americans (AA) and Haitian Americans (HA) with and without type 2 diabetes using the Healthy Eating Index, 2005 (HEI-05), and the Alternate Healthy Eating Index (AHEI). The design was cross-sectional (225 AA, 246 HA) and recruitment was by community outreach. The eating indices were calculated from data collected with the Harvard food-frequency questionnaire. African Americans had lower HEI-05 scores (−8.67, 13.1); , than HA. Haitian American females and AA males had higher AHEI than AA females and HA males, respectively, () adjusting for age and education. Participants with diabetes had higher adherence to the HEI-05 (1.78, 6.01), , and lower adherence to the AHEI (16.3, −3.19), , , than participants without diabetes. The findings underscore the importance of disaggregating ethnicities and disease state when assessing diet.


2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Amanpreet K. Cheema ◽  
Tan Li ◽  
Juan P. Liuzzi ◽  
Gustavo G. Zarini ◽  
Mehmet T. Dorak ◽  
...  

The aim of this study was to assess the differences in correlation ofPPARGC1Apolymorphisms with type 2 diabetes (T2D) risk in adults of African origins: African Americans and Haitian Americans. The case-control study consisted of >30 years old, self-identified Haitian Americans (n=110cases andn=116controls) and African Americans (n=124cases andn=122controls) living in South Florida with and without T2D. Adjusted logistic regression indicated that both SNP rs7656250 (OR = 0.22,P=0.005) and rs4235308 (OR = 0.42,P=0.026) showed protective association with T2D in Haitian Americans. In African Americans, however, rs4235308 showed significant risk association with T2D (OR = 2.53,P=0.028). After stratification with sex, in Haitian Americans, both rs4235308 (OR = 0.38,P=0.026) and rs7656250 (OR = 0.23,P=0.006) showed protective association with T2D in females whereas in African American males rs7656250 had statistically significant protective effect on T2D (OR = 0.37,P=0.043). The trends observed for genetic association ofPPARGC1ASNPs, rs4235308, and rs7656250 for T2D between Haitian Americans and African Americans point out differences in Black race and warrant replicative study with larger sample size.


2021 ◽  
pp. 014572172199628
Author(s):  
Jennifer A. Campbell ◽  
Alice Yan ◽  
Renee E. Walker ◽  
Lance Weinhardt ◽  
Yang Wang ◽  
...  

Purpose The purpose of this study is to examine the association of individual, community, and health system factors on quality of life among inner-city African Americans with type 2 diabetes. Methods Primary data from a cross-sectional study with a community sample of 241 inner-city African Americans with type 2 diabetes were analyzed. Paper-based surveys were administered in which the SF-12 was used to capture the physical component (PCS) and mental component (MCS) of quality of life. Four regression approaches (sequential, stepwise with backward and forward selection, and all possible subsets regression) were used to examine the influence of individual, community, and health system factors on PCS and MCS after adjusting for relevant covariates using a conceptual framework. Results In fully adjusted models, having less than a high school education and having major depression were associated with lower quality-of-life scores for MCS across all 4 regression approaches. Being employed was positively associated with better quality-of-life scores for PCS across all 4 regression approaches. PCS was higher across all 4 regression approaches for those reporting a history of trauma. At the health systems level, usual source of care was associated with better PCS across 3 regression approaches. Conclusions These results highlight key factors that influence quality of life among inner-city African Americans with type 2 diabetes that could be targets for interventions in this population. However, additional research is needed to understand existing pathways that may be driving many of these relationships.


2006 ◽  
Vol 29 (1) ◽  
pp. 69-78 ◽  
Author(s):  
Felicia Hill-Briggs ◽  
Tiffany L. Gary ◽  
Hsin-Chieh Yeh ◽  
Marian Batts-Turner ◽  
Neil R. Powe ◽  
...  

Diabetes Care ◽  
2002 ◽  
Vol 25 (1) ◽  
pp. 9-15 ◽  
Author(s):  
D. M. Erdman ◽  
C. B. Cook ◽  
K. J. Greenlund ◽  
W. H. Giles ◽  
I. El-Kebbi ◽  
...  

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 584-P
Author(s):  
JACLYNN M. HAWKINS ◽  
NIKOLAS J. KOSCIELNIAK ◽  
ROBIN NWANKWO ◽  
MARTHA M. FUNNELL ◽  
KATHERINE A. KLOSS ◽  
...  

2018 ◽  
Vol 132 (23) ◽  
pp. 2509-2518 ◽  
Author(s):  
Gargi Mahapatra ◽  
S. Carrie Smith ◽  
Timothy M. Hughes ◽  
Benjamin Wagner ◽  
Joseph A. Maldjian ◽  
...  

Blood-based bioenergetic profiling has promising applications as a minimally invasive biomarker of systemic bioenergetic capacity. In the present study, we examined peripheral blood mononuclear cell (PBMC) mitochondrial function and brain morphology in a cohort of African Americans with long-standing Type 2 diabetes. Key parameters of PBMC respiration were correlated with white matter, gray matter, and total intracranial volumes. Our analyses indicate that these relationships are primarily driven by the relationship of systemic bioenergetic capacity with total intracranial volume, suggesting that systemic differences in mitochondrial function may play a role in overall brain morphology.


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