scholarly journals Effects of cytoflavin on biochemical indicators in patients with maxillofacial area phlegmons

2020 ◽  
Vol 27 (1) ◽  
pp. 18-26
Author(s):  
Tatiana V. Gaivoronskaya ◽  
Oksana V. Shvets ◽  
Svetlana K. Shafranova

Aim. To assess the effect of cytoflavin on the dynamics of the blood and oral fluid prooxidant-antioxidant system in patients with maxillofacial area phlegmons.Materials and methods. 55 patients were included in the study. The patients were divided into three groups: control group (group 1, n = 20); comparison group (group 2, n = 15); patients with phlegmons of the maxillofacial area (group 3, n = 20). As part of therapy, the patients in group 3 were additionally receiving cytoflavin (10 ml cytoflavin in 200 ml saline solution, 1 time per day, for 6 days). The treatment and monitoring was performed over the period of 6 days, during which the blood and oral fluid indicators were estimated 4 times (day 1, 2, 4 and 6).Results. Cytoflavin had a positive effect on the state of the prooxidant-antioxidant balance in patients with maxillofacial area phlegmons. In comparison with the control group, patients in group 3 demonstrated a lower content of oxidative modifi cation products and a higher antioxidant activity of blood plasma. Cytoflavin therapy also led to an increase in the activity of glutathione peroxidase and reductase, as well as an increase in the concentration of glutathione at the last stage of the therapy.Conclusion. The obtained data indicate the potential of cytoflavin as part of complex metabolic therapy for patients with purulent inflammatory processes of the maxillofacial area. 

2021 ◽  
Vol 935 (1) ◽  
pp. 012041
Author(s):  
V G Semenov ◽  
E P Simurzina ◽  
S G Kondruchina ◽  
V G Tyurin ◽  
A F Kuznetsov ◽  
...  

Abstract The article describes the results of comparative studies on the influence of new immunostimulants on the course of postnatal recovery of the cows under conditions of intensive milk production technology. Injections of PS-2 (group 1) and Prevention-N-E (group 2) at a dose of 10 ml forty, twenty and ten days before calving, and a injection of PDE at a dose of 20 ml with E-Selenium of 10 ml (group 3) twenty days before calving prevent the occurrence of obstetric and gynecological pathology, improve reproductive qualities, as compared to the control group, where no biologicals were injected. This fact impacts the acceleration of the first heat onset by 13.7-21.1 days, the conception rate by 0.5-0.7 times, the service period by 16-29.9 days. A positive effect of the tested agents on metabolic processes, morphological and biochemical blood parameters, nonspecific immunological reactivity of the organism was also established. All these factors led to an increase in milk productivity for 305 days of lactation by 186-478 kg, at the same time, milk quality indicators improved correspondingly. Thus, biological preparations PS-2 and Prevention-N-E are highly effective means of preventing obstetric and gynecological pathology.


2021 ◽  
Vol 1 (2) ◽  
pp. 7-11

White vinegar is mildly acidic with a pH of 2-3 that has long been used as a relish and traditional medication that depends on its concentration. Yet even a small amount of white vinegar in a small concentration may cause serious poisoning. Recently, many sorts of white vinegar have been developed using fundamental sources and technologies to satisfy customer needs. This study was aimed to investigate the effects of white vinegar on carbohydrate contents in hepatorenal tissues in rats. Thirty female rats were used, they were divided into three groups, group 1 was given distilled water as the normal control group, group 2 was given white vinegar with a dose (1 ml/kg (5 %)) and group 3 was given white vinegar with a dose (1 ml/kg (10 %)) for two weeks. PAS stain in all treated tissues showed a decrease in carbohydrate contents when compared with the control group. In conclusion, white vinegar consumption has adverse effects on carbohydrate contents in hepatic and renal tissues in rats, hence the quantity of white vinegar should be discouraged or reduced.


2009 ◽  
Vol 21 (1) ◽  
pp. 105
Author(s):  
I. Hernandez-Caravaca ◽  
M. J. Izquierdo-Rico ◽  
F. A. Garcia-Vazquez

In the current procedures for AI in pigs, billions of spermatozoa are used (2.5–4.0 × 109 spermatozoa per insemination) in a large volume of liquid (70–100 mL), which is deposited in the cervix at the moment of AI. Approximately 90% of the spermatozoa inseminated cannot be recovered from the uterus at 2 h after AI (Viring S et al. 1980 Acta Vet. Scand. 21, 145–149). Several technical methods are used in the pig production industry for semen application using AI. To reduce the number of spermatozoa, several methods have been developed. The present study was performed to evaluate the reproductive effects under field conditions of postcervical AI (post-CAI) in southeast Spain with multiparous sows. In total, 509 sows were inseminated and divided in 3 groups: sows in the first group were inseminated using cervical AI (CAI, control group) with 3 × 109 spermatozoa in 80 mL of extender (group 1, n = 168); sows in the second group were inseminated by post-CAI using 1.5 × 109 spermatozoa in 40 mL of extender (group 2, n = 175); and sows in the third group were inseminated by post-CAI but using 1 × 109 spermatozoa in 26 mL of extender (group 3, n = 166). The catheter used for post-CAI consisted of a conventional AI catheter with an additional inner catheter that could extend past the catheter tip (Soft & Quick®, Import-Vet, Barcelona, Spain). Day 28 of pregnancy rates, farrowing rates, total pigs born, total live piglets, and stillborns were evaluated. Data were analyzed by ANOVA. Pregnancy and farrowing rates after post-CAI with 1.5 × 109 or 1 × 109 spermatozoa did not differ from those of the control group (group 1: 87.50%; group 2: 88.57%; group 3: 86.14%; P = 0.367). The number of spermatozoa inseminated did not significantly affect the number of live (12.27 ± 4.99; 12.18 ± 5.20; 12.64 ± 5.31; P = 0.946) or stillborn pigs (1.60 ± 1.79; 1.80 ± 2.27; 1.78 ± 1.84; P = 0.386) or the total number of piglets born (13.87 ± 5.39; 14.02 ± 5.75; 14.42 ± 5.65; P = 0.865). The present study shows that post-CAI with a low number of sperm cells does not negatively influence the reproductive parameters of multiparous sows compared with conventional AI. In conclusion, post-CAI in sows is simple, effective, and safe, and allows the sperm dose to be reduced to one billion spermatozoa.


Author(s):  
Daniel BEREAN ◽  
Liviu Marian BOGDAN ◽  
Ileana BOGDAN ◽  
Ovidiu GIURGIU ◽  
Anamaria Blaga PETREAN ◽  
...  

The purpose of this research was to evaluate a product developed at the Faculty of Veterinary Medicine of Cluj Napoca and his efficiency in the control of the puerperium at cows. The study was carried out between January 2017 to December 2018 in a dairy farm from Mures county, Romania. In this study were enclosed 60 cows, randomly divided in 3 groups: Puerperal group (group 1), Puerperal and Estrumate group (group 2), and control group (group 3). For each group the treatment applied for the control of puerperium was different. For each group were followed: the evolution of puerperium, the appearance of the first postpartum estrous cycle, the interval of service period and the number of artificial inseminations necessary for one gestation. For the puerperium control and to avoid the postpartum complications Puerperal intrauterine suspension it’s a good option.


2008 ◽  
Vol 77 (4) ◽  
pp. 503-508 ◽  
Author(s):  
M. Skalická ◽  
B. Koréneková ◽  
P. Naď ◽  
J. Šály

The experiment was conducted to evaluate the effect of chromium (Cr) and cadmium (Cd) on the quality of Japanese quail eggs. The birds (n = 60) were divided into 3 groups of 20 animals each. Group 1 was the control group. Group 2 was administered 0.12 mg Cr/day (Cr group) per quail in drinking water, whereas Group 3 was given a combination of 0.12 mg Cd and 0.12 mg Cr/ day (Cd-Cr group). The distribution of Cd in eggs, the egg mass, and the strength and thickness of shells was determined after after Day 35 and 58 of administration. Addition of Cr had a positive effect on the weight of eggs. A significant decrease of eggshell strength (p < 0.05) and thickness was found after Day 35 and 58 of the experiment in the Cd-Cr group (3) in comparison to the Cr-only group (2) and the control group (1). The content of Cd was significantly lower (p < 0.05) in eggshells and in the egg yolk from the Cr-only group (2) in comparison to the Cd-Cr group (3) and the control group (1). The data show that addition of Cr can improve quality indicators of quail eggs and eliminate the negative effect of Cd.


2014 ◽  
Vol 43 (3) ◽  
pp. 191-195 ◽  
Author(s):  
Matheus Melo PITHON ◽  
Jéssica Rocha BARRETTO ◽  
Camilla Souza Santos ANDRADE ◽  
Fernando Pereira de NOVAES ◽  
Murilo de Novaes LUZ ◽  
...  

Objective: To evaluate the effects of different alcoholic beverages on the decline in force of orthodontic elastics. Material and method: In a laboratory study, 6 groups of alcoholic beverages were tested. Control group (Group 1) was composed of distilled water. Experimental groups were Whisky (Group 2), Brandy (Group 3), Vodka (Group 4), Beer (Group 5), Sugar Cane Spirit/Rum (Group 6), Wine (Group 7). In the experimental groups, templates were used to enable elastics to be submerged in the alcoholic beverages for 30 seconds once a day. Force was measured with a digital dynamometer in six different time intervals: baseline, 1, 7, 14, 21 and 28 days. Result: There were no significant differences between the treatments in the time intervals: baseline, 7, 14 and 28 days. There were statistical differences between Group 7 and the others in the first 24 hours, and between Group 1 and the others after 21 days. After 28 days, there were no significant differences in the force pattern among all groups (p<0.05). Conclusion: Alcoholic beverages had no influence on the decline in force of the chain elastics.


2000 ◽  
Vol 14 (7) ◽  
pp. 588-592 ◽  
Author(s):  
László Madi-Szabo ◽  
György Kocsis

BACKGROUND: Ultrasound can visualize significant portions of the upper and lower esophagus; it is without any instrumental interference in real conditions and displays events in motion.PURPOSE: To study the events that occur during swallowing and gastroesophageal reflux.PATIENTS AND METHODS: Group 1 comprised 25 patients with retrosternal complaints, selected for esophageal surface ultrasonography for endoscopic signs of esophagitis. Group 2 comprised 25 patients who underwent initial transabdominal ultrasonography. For 3 to 6 h before ultrasonography, nothing was given by mouth to the 50 patients labelled as having gastroesophageal reflux disease (GERD). Ultrasonography was then performed for 15 to 20 mins after drinking one mouthful of water or tea, or swallowing some saliva to provoke reflux. The events were recorded on videotape rolls. Endoscopy was carried out in all 50 cases; in 46 cases (21 and 25 from groups 1 and 2, respectively), gastric acidity and bacteriology were subsequently examined (test meal). Manometry and pH were not measured to avoid provocation of reflux by the instruments. Thirty patients without any esophageal complaints or signs of esophagitis (though suffering from gastric and duodenal diseases) were designated as the control group (group 3). The available results were compared.RESULTS: In 32 of 46 patients diagnosed with GERD (69.5% in groups 1 and 2), a special kind of reflux was observed by ultrasonography: a slow, trickling reflux of the gastric content was seen, mostly after swallowing. A fast clearance followed four to six episodes of the trickling reflux, only after an interval of 0.5 to 2 mins. Only fast refluxes and immediate clearance were observed in the control group.CONCLUSIONS: The observations above may indicate a special form of gastroesophageal reflux, namely, a slow, trickling form of it. It can be responsible for the development of GERD. Fast reflux and immediate clearance are common; however, this special trickling form was observed only in GERD patients. This may explain a number of often contradictory measurements and can make the effect of cisapride more understandable. A test meal is always necessary to distinguish a bilious reflux from an acidic one, because only the latter may require aggresive antacidic treatment.


1971 ◽  
Vol 45 (2-3) ◽  
pp. 177-187 ◽  
Author(s):  
R. M. Connan

The resistance to infection by Ostertagia spp. of three groups of lactating ewes was compared with an unbred control group. Group 1 was fed a full diet of hay and a concentrate ration ad lib. Groups 2 and 3 were fed the same quantitatively inadequate diet and in addition group 3 received daily injections of thyroxine sodium. All the animals were infected regularly with Ostertagia larvae and killed 6 weeks after lambing.While the unbred sheep were highly resistant, all three groups of lactating ewes carried significant numbers of worms. Group 2 and 3 had significantly more than group 1, the additional worms being present as adults. The effect of hyperthyroidism in group 3 was not significant.It is concluded that the immuno-suppressant effect of lactation is probably not due to protein depletion although the latter may be an important secondary factor.


Author(s):  
D. Berean ◽  
O. Ergene ◽  
A. Blaga-Petrean ◽  
I. Bogdan ◽  
S. Ciupe ◽  
...  

Backgroung: Seasonal anestrus in ewes reduces reproductive efficiency and hinders productivity. Exogenous hormones can be used to facilitate the induction and synchronization of estrus in the anestrus period. The aim of this study was to evaluate the pregnancy rate in ewes after the treatment with different hormones and fixed time artificial insemination. Methods: The ewes were randomly divided in 4 (n=4) groups: Melatonin group (Group 1), Melatonin and Medroxyprogesterone group (Group 2), Medroxyprogesterone group (Group 3) and control group (Group 4). Pregnancy rate, estrus induction rate and litter size were determined and compared. Result: The estrus induction rate in our study was 100% for the first 3 groups and 6.25% for the 4th group. The pregnancy rate was between 4.16% (group 4) and 95.83% (group 2). For the others groups the values were 89.58% for the first group and 91.67%, for the 3rd group. The prolificacy rate was between 1 (control group) and 1.71 (2nd group), with intermediate values for the other 2 groups: 1.21 for 1st group and 1.27 for the 3rd group.


Author(s):  
Sanjay U. Nipanikar ◽  
Sohan S. Chitlange

Background: Adverse effects of available medications for osteoarthritis (OA) and rheumatoid arthritis (RA) necessitate development of safer and effective alternative medicinal substitutes. The present study was conducted to evaluate analgesic activity of Ariflex liniment (conceptualized and developed by Ari Healthcare Pvt. Ltd.) in comparison with diclofenac gel by using acetic acid induced writhing model.Methods: Albino mice of either sex weighing 20-25 g were taken and divided into 3 groups with 5 animals in each group, i.e., group 1 (control group), group 2 (diclofenac gel) and group 3 (Ariflex liniment). After 1 hour of topical application of study drugs writhing was induced in mice using intra-peritonial injection of 1% acetic acid in volume of 0.1 ml/10 g body weight. Then the writhing episodes were recorded for 30 minutes and results were noted.Results: In the control group, the total number of  writhes were 260±29.73 (mean±S. E. M.). The total number of writhes was 12.17±11.81 (mean ± S. E. M.) in diclofenac group. In Ariflex liniment group, not a single animal felt pain, hence there were no writhes recorded. When compared to control group, the difference in number of writhes was statistically significant. The analgesic activity of Ariflex liniment was found to be superior to that of diclofenac gel used as standard drug.Conclusions: It can be concluded that Ariflex liniment possesses analgesic activity.


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