scholarly journals Studying the Frequency of Autoimmune Thyroid Diseases in Duhok Province

2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Rozheen I. Hasan ◽  
Amir H. Raziq
Keyword(s):  
Venous Blood ◽  
Serum Levels ◽  
Control Group ◽  
Thyroid Disorder ◽  
Control Groups ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Significant Difference ◽  
The One ◽  
And Control

Thyroid disorders are one of the most frequent disorders affecting endocrine system. The present study aimed to identify the frequency of thyroid disorder in our locality at Duhok city. To do so, a total of one hundred patients and one hundred apparently healthy control individuals were enrolled in this study. Samples of venous blood (5 ml) were withdrawn from patients and control subjects and analysed. Clinical assessment was performed by a specialist and each patient provided with a document supporting preliminary clinical diagnosis. Measurements of serum TSH, T3, T4, and anti-thyroperoxidase antibodies (anti-TPO antibodies) serum levels were performed. All assays were conducted at Duhok central health laboratory. Out of the one hundred patients and the one hundred control groups, forty-two and thirty candidates were randomly selected, respectively. The mean TSH serum levels of 25.87 (uIU/ml) for the patients significantly differ from that of the control group 3.55 (uIU/ml) (p<0.001). However, T3 and T4 serum levels indicated no significant difference between the two categories. Moreover, there was statisticaly significant difference (p< 0.0001) between the patients and control groups when their mean serum anti-TPO concentrations were compared.  In conclusion, considerable number of subjects appeared to be candidates for deranged thyroid functions and is susceptible to autoimmune thyroid disorder.

Plasma kisspeptin and ghrelin levels in puberty variant cases

2017 ◽  
Vol 30 (5) ◽  
Author(s):  
Erdal Kurnaz ◽  
Yaşar Şen ◽  
Süleyman Aydın
Keyword(s):  
Serum Levels ◽  
Control Group ◽  
Control Groups ◽  
Premature Thelarche ◽  
Premature Adrenarche ◽  
Significant Difference ◽  
And Gender ◽  
And Control ◽  
Relationship Of ◽  
The Relationship

AbstractBackground:The aim of this study was to determine the serum levels of kisspeptin and ghrelin (GAH), as well as the relationship of these two peptides with each other in premature thelarche (PT) and premature adrenarche (PA) cases and to investigate the possibility of using these peptides as markers in the differentiation of puberty disorders.Methods:A PT group aged 1–8 years (n = 40), a PA group aged 1–9 years (n = 23, female/male = 20/3) and control groups consistent with each of the previous groups in terms of age and gender were created for the study. Kisspeptin and ghrelin levels were measured with ELISA methods from blood samples drawn while fasting in the morning.Results:When the PT group was compared with the controls, the plasma kisspeptin levels of the cases were significantly higher than the control group (165.47 ± 15.45 pmol/L, 96.82 ± 12.33 pmol/L, p = 0.005, respectively). Kisspeptin levels in the PA group did not show a difference with the control group (121.36 ± 17.99 pmol/L, 95.52 ± 11.54 pmol/L, p = 0.249, respectively). No significant difference could be found when GAH levels in the PT and PA groups were compared with controls. No significant correlation was found between kisspeptin and GAH levels in the PT and PA groups.Conclusions:Our results indicate that kisspeptin plays an important role in the PT, but GAH is not associated with puberty disorders.

Effect of short- and long-acting growth promotants on grazing beef cattle in south-west Queensland.

1988 ◽  
Vol 10 (1) ◽  
pp. 30 ◽  
Author(s):  
MR Clarke ◽  
JR Wythes
Keyword(s):  
Beef Cattle ◽  
Control Group ◽  
Control Groups ◽  
Short Acting ◽  
South West ◽  
Significant Difference ◽  
The One ◽  
Long Acting ◽  
Growth Promotants ◽  
And Control

The effects of a single implantation of a short-acting (< 120 days) growth promotant - 36 mg zeranol (Ralgro) - were studied with one, two and three year old steers grazing Mitchell (Astrebla spp.) grasslands from March to June 1981 (107 days) in south-west Queensland. Implantation increased (P<0.05) mean final liveweight by 9.7, 18.1 and 11.0 kg for the one, two and three year old steers, respectively (control groups 317.6 kg, 432.3 kg and 519.1 kg). Tn a second experiment, the effects of a single implantation of a long-acting (400 days) growth promotant - 45 mg oestradiol 17 beta (Compudose 400) - were studied with steers grazing Channel pastures from October 1983 to April 1985 (540 days) in far south-west Queensland. Implantation increased (P<0.01) both mean final liveweight by 30.7 kg (control group 577.1 kg) and carcass weight by 14.2 kg (control 306.4 kg). Daily liveweight gains for implanted and control steers were 0.48 kg and 0.43 kg per day respectively @<0.01). There was no significant difference between the implanted and control steers in dressing percentage (52.7 cf. 53.2%) and fat ;hicknes.s at the P8 rump sGe (20.2 cf. 18.9 mm).

scholarly journals Comparison of the Effects of Hugo’s Point Massage and Play on IV-Line Placement Pain in Children: A Randomized Clinical Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Shahnaz Salawati Ghasemi ◽  
Mehdi Beyramijam ◽  
Fatemeh Yarahmadi ◽  
Taban Nematifard ◽  
Seyed Shahabeddin Bahrani ◽  
...  
Keyword(s):  
Control Group ◽  
Pediatric Nurses ◽  
Control Groups ◽  
Line Placement ◽  
Significant Difference ◽  
Massage Group ◽  
The Mean ◽  
The One ◽  
Children's Pain ◽  
And Control

Reduction of intravenous line placement pain is one of the most important nursing priorities in the pediatric wards. The present study was aimed at comparing the effect of Hugo’s point massage and play on the severity of IV-line placement pain in hospitalized children aged 3–6 years in the pediatric ward. 72 children were selected and assigned randomly to three groups, i.e., control, play, and Hugo point massage. In the massage group, the middle angle between the first and second bones of the palm of the opposite hand was massaged, and the playgroup encouraged bubble-making play. The one-way analysis of variance (ANOVA) did not show a statistically significant difference between the mean IV-line placement pain in play, Hugo’s point, and control groups before interventions ( p = 0.838 ; p > 0.05 ). However, the ANOVA test revealed a significant difference between the mean IV-line placement pain in play, Hugo’s point, and control groups after the interventions ( p = 0.006 ; p < 0.05 ). The result of the post hoc Scheffe test also showed a statistically significant difference between the mean intensity of IV-line placement pain in both play therapy and Hugo’s point massage groups ( p = 0.028 ; p < 0.05 ). Moreover, this test showed that the playgroup children felt less pain than Hugo’s point and control group children. This study showed that, in comparison with Hugo’s point massage, the play was a more effective way for reducing pain caused by IV-line placement in children, and pediatric nurses can play a significant role in reducing and managing children’s pain by using it.

Genetic polymorphisms affecting antioxidant enzymes are present in tympanosclerosis patients

2016 ◽  
Vol 130 (10) ◽  
pp. 928-933 ◽  
Author(s):  
A Akyigit ◽  
Ş Yalcin ◽  
E Ö Etem ◽  
İ Kaygusuz ◽  
T Karlidag ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Otitis Media ◽  
Venous Blood ◽  
Chronic Otitis Media ◽  
Study Groups ◽  
Control Group ◽  
Genotype Distribution ◽  
Control Groups ◽  
Significant Difference ◽  
And Control

AbstractBackground:This study investigated genetic polymorphisms affecting the inducible nitric oxide synthase, superoxide dismutase and catalase enzymes in chronic otitis media patients with and without tympanosclerosis, and the role of genetic susceptibility in the disease aetiology.Methods:A total of 162 patients who underwent surgery for chronic otitis media were divided into two study groups: a tympanosclerosis group and a chronic otitis media group. A third, the control, group comprised 188 healthy volunteers. Venous blood samples were evaluated using reverse transcriptase polymerase chain reaction.Results:There was a significant difference in GG genotype distribution of the −277A>G polymorphism in the NOS2 gene between the tympanosclerosis and control groups (p < 0.05). However, there were no significant between-group differences in the CC genotype distribution of the p.Ala16Val (C>T) polymorphism in the SOD2 gene (p > 0.05). There were significant differences in the TT genotype distribution of the −21A>T polymorphism in the CAT gene between the tympanosclerosis and control groups, and between the chronic otitis media and control groups (p < 0.05).Conclusion:These results suggest that genetic predisposition may play a role in the aetiopathogenesis of tympanosclerosis.

scholarly journals There Is No Elevation of Immunoglobulin E Levels in Albanian Patients with Autoimmune Thyroid Diseases

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Hatixhe Latifi-Pupovci ◽  
Besa Gacaferri-Lumezi ◽  
Violeta Lokaj-Berisha
Keyword(s):  
Immunoglobulin E ◽  
Allergic Diseases ◽  
Serum Levels ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Diseases ◽  
Control Group ◽  
Graves Disease ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Significant Difference

Background. Studies in several ethnic groups reported high incidence of elevated levels of immunoglobulin E (IgE) in patients with autoimmune thyroid diseases (ATD), especially in patients with Graves’ disease.Objective. To study association between serum levels of IgE and thyroid stimulating hormone receptor antibodies (TRAb) in Albanian patients with ATD.Material and Methods. Study was performed in 40 patients with Graves’ disease, 15 patients with Hashimoto’s thyroiditis, and 14 subjects in the control group. The IgE levels were measured by immunoradiometric assay, whereas the TRAb levels were measured by radioreceptor assay.Results. In all groups of subjects the IgE levels were within reference values (<200 kIU/L). Significant difference in mean concentration of IgE was found between two groups of Graves’ disease patients, and those with normal and elevated TRAb levels (22.57 versus 45.03,P<0.05). Positive correlation was found between TRAb and IgE only in Graves’ disease patients (r=0.43,P=0.006).Conclusion. In Albanian patients with ATD there is no elevation of IgE levels. This could be the result of low prevalence of allergic diseases in Albanian population determined by genetic and environmental factors.

scholarly journals Serum Prolactin Levels in Psoriasis Vulgaris

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Farhad Handjani ◽  
Nasrin Saki ◽  
Iman Ahrari ◽  
Mehdi Ebrahimi ◽  
Mohammad Mehdi Khorrami ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Normal Population ◽  
Venous Blood ◽  
Human Keratinocytes ◽  
Serum Levels ◽  
Serum Prolactin ◽  
Control Group ◽  
Significant Difference ◽  
Dominant Feature ◽  
And Control

Background. Psoriasis is a chronic inflammatory skin disease affecting approximately 1–3% of Caucasians. Prolactin has proliferative effects on human keratinocytes, a dominant feature of psoriasis, and it is thought that this hormone may play a role in the pathogenesis of the disease. This study was conducted to confirm or refute these findings in order to better understand the disease pathogenesis. Methods. The subjects were 90 individuals aged between 15 and 47 years. They were divided into three groups of 30 individuals each: psoriatic patients, atopic dermatitis patients, and control group. A questionnaire was filled regarding their demographic and medical history. All of the study subjects underwent venous blood sampling (5 mL), and serum TSH and prolactin levels were checked. Subjects with abnormal TSH were omitted. Results. None of the patients in the study had raised prolactin, and there was no significant difference in the serum prolactin level between patients with psoriasis and atopic dermatitis and the control group. There was no relationship between the severity of psoriasis and serum levels of prolactin. Conclusion. Prolactin does not seem to play a role in the pathogenesis of psoriasis as its serum levels are comparable with atopic dermatitis patients and that of the normal population.

scholarly journals Preoperative Serum Levels of Mesothelin in Patients with Colon Cancer

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Özgür Bostancı ◽  
Özgür Kemik ◽  
Ahu Kemik ◽  
Muharrem Battal ◽  
Uygar Demir ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Perineural Invasion ◽  
Tumor Grade ◽  
Serum Levels ◽  
Control Group ◽  
Control Groups ◽  
Colonoscopic Examination ◽  
Preoperative Serum ◽  
Significant Difference ◽  
And Control

Background. Screening for biochemical markers is important for diagnosing colon cancer. In this study, the reliability of serum mesothelin levels as a potential diagnostic and screening instrument was evaluated concerning colon cancer.Methods. Ninety-five patients who had undergone colonoscopic examination and who were diagnosed with colon cancer were included in the study. The serum mesothelin levels were measured with the ELISA kits and were evaluated in terms of significant difference when compared between colon cancer and control group.Results. Patients with colon cancer had significantly higher mesothelin serum levels(P<0.001)than the control groups. We found significant associations between serum levels and tumor grade, perineural invasion, and vascular invasion (resp.,P<0.001).Conclusion. Evaluating the serum levels of mesothelin has a potential to detect and screen the colon cancer in affected patients. Our data suggest that mesothelin exhibits effects towards colon cancer and serves as a biomarker for this deadly disease.

scholarly journals Determination of the role of polymorphic variants of the interferon-gamma gene (IFNG) in the development of tuberculosis in the Yakut population

2021 ◽  
Vol 98 (12) ◽  
pp. 27-32
Author(s):  
L. I. Mordovskaya ◽  
M. V. Egorova ◽  
T. M. Klimova ◽  
S. D. Аlekseeva
Keyword(s):  
Venous Blood ◽  
Statistical Processing ◽  
Control Group ◽  
Case Group ◽  
Control Groups ◽  
Significant Difference ◽  
Hardy Weinberg Equilibrium ◽  
Polymorphic Variants ◽  
And Control

The objective of the study: to determine the role of polymorphic variants T6000A (rs2430561), T8360C (rs2069718) of the IFNG gene in the development of tuberculosis in the population of Yakut nationality.Subjects and methods. The case-control study was conducted. The subject for the study was DNA samples from 172 tuberculosis patients (the case group) and 367 people with an excluded diagnosis of tuberculosis (the control group). All participants of the study belonged to Yakut nationality. For genotyping, DNA was isolated from venous blood. The genotyping was performed by real-time polymerase chain reaction. For statistical processing, Pearson's χ2 test and odds ratio with 95% confidence intervals were used.The results of the study showed that the distribution of genotypes of polymorphisms T6000A (rs2430561), T8360C (rs2069718) of the IFNG gene in the case and control groups corresponded to the Hardy – Weinberg equilibrium. There was no statistically significant difference in frequencies of alleles and genotypes of polymorphisms T6000A (rs2430561), T8360C (rs2069718) of the IFNG gene in the patients from the case and control groups.Conclusions. The results of the study did not reveal the association of alleles and genotypes of the rs2430561 and rs2069718 polymorphic variants of the IFNG gene with the risk of developing tuberculosis for people of Yakut nationality.

Effects of Virgin Coconut Oil as Adjunct Therapy in the Treatment of Allergic Rhinitis

2016 ◽  
Vol 1 (1) ◽  
pp. 22
Author(s):  
Nazli Zainuddin ◽  
Nurul Azira Mohd Shah ◽  
Rosdan Salim
Keyword(s):  
Allergic Rhinitis ◽  
Side Effects ◽  
Coconut Oil ◽  
Test Group ◽  
Nasal Symptom ◽  
Control Group ◽  
Virgin Coconut Oil ◽  
Control Groups ◽  
Significant Difference ◽  
And Control

Introduction: The role of virgin coconut oil in the treatment of allergic rhinitis is controversial. Thus, the aim of the present study is to determine the effects of virgin coconut oil ingestion, in addition to standard medications, on allergic rhinitis. We also studied the side effects of consumption of virgin coconut oil. Methods: Fifty two subjects were equally divided into test and control groups. All subjects received a daily dose of 10mg of loratadine for 28 days. The test group was given 10ml of virgin coconut oil three times a day in addition to loratadine. The symptoms of allergic rhinitis were scored at the beginning and end of the study. Results:, the symptom score were divided into nasal and non-nasal symptom scores. Sneezing score showed a significant difference, however the score was more in control group than test group, indicating that improvement in symptom was more in control group. The rest of the nasal symptom and non-nasal symptom score showed no significant difference between test and control groups. Approximately 58% of the test subjects developed side effects from consumption of virgin coconut oil, mainly gastrointestinal side effects. Conclusion: In the present study, ingestion of virgin coconut oil does not improve the overall and individual symptoms of allergic rhinitis, furthermore it has side effects.

Impact of intrawound vancomycin powder on prevention of surgical site infection after posterior spinal surgery

2021 ◽  
pp. 1-9
Author(s):  
Hiroki Ushirozako ◽  
Tomohiko Hasegawa ◽  
Yu Yamato ◽  
Go Yoshida ◽  
Tatsuya Yasuda ◽  
...  
Keyword(s):  
Propensity Score ◽  
Spinal Surgery ◽  
Control Group ◽  
Control Groups ◽  
Propensity Score Model ◽  
Significant Difference ◽  
Surgical Data ◽  
Vancomycin Powder ◽  
Vancomycin Group ◽  
And Control

OBJECTIVESurgical site infection (SSI) after posterior spinal surgery is one of the severe complications that may occur despite administration of prophylactic antibiotics and the use of intraoperative aseptic precautions. The use of intrawound vancomycin powder for SSI prevention is still controversial, with a lack of high-quality and large-scale studies. The purpose of this retrospective study using a propensity score–matched analysis was to clarify whether intrawound vancomycin powder prevents SSI occurrence after spinal surgery.METHODSThe authors analyzed 1261 adult patients who underwent posterior spinal surgery between 2010 and 2018 (mean age 62.3 years; 506 men, 755 women; follow-up period at least 1 year). Baseline and surgical data were assessed. After a preliminary analysis, a propensity score model was established with adjustments for age, sex, type of disease, and previously reported risk factors for SSI. The SSI rates were compared between patients with intrawound vancomycin powder treatment (vancomycin group) and those without (control group).RESULTSIn a preliminary analysis of 1261 unmatched patients (623 patients in the vancomycin group and 638 patients in the control group), there were significant differences between the groups in age (p = 0.041), body mass index (p = 0.013), American Society of Anesthesiologists classification (p < 0.001), malnutrition (p = 0.001), revision status (p < 0.001), use of steroids (p = 0.019), use of anticoagulation (p = 0.033), length of surgery (p = 0.003), estimated blood loss (p < 0.001), and use of instrumentation (p < 0.001). There was no significant difference in SSI rates between the vancomycin and control groups (21 SSIs [3.4%] vs 33 SSIs [5.2%]; OR 0.640, 95% CI 0.368–1.111; p = 0.114). Using a one-to-one propensity score–matched analysis, 444 pairs of patients from the vancomycin and control groups were selected. There was no significant difference in the baseline and surgical data, except for height (p = 0.046), between both groups. The C-statistic for the propensity score model was 0.702. In the score-matched analysis, 12 (2.7%) and 24 (5.4%) patients in the vancomycin and control groups, respectively, developed SSIs (OR 0.486, 95% CI 0.243–0.972; p = 0.041). There were no systemic complications related to the use of vancomycin.CONCLUSIONSThe current study showed that intrawound vancomycin powder was useful in reducing the risk of SSI after posterior spinal surgery by half, without adverse events. Intrawound vancomycin powder use is a safe and effective procedure for SSI prevention.

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