Does suspicion of Ebola virus disease have consequences on the diagnosis delay for other infectious diseases?

2016 ◽  
Author(s):  
Pierre Tattevin
Keyword(s):  
Infectious Diseases ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Diagnosis Delay

scholarly journals Ebola virus disease: Case management in the Institute of Infectious Diseases, University Hospital of Sassari, Sardinia, Italy

2016 ◽  
Vol 10 (05) ◽  
pp. 537-543 ◽  
Author(s):  
Giulia Bertoli ◽  
Marco Mannazzu ◽  
Giordano Madeddu ◽  
Riccardo Are ◽  
Alberto Muredda ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Ebola Virus ◽  
Virus Disease ◽  
Developed Countries ◽  
The United States ◽  
Ebola Virus Disease ◽  
University Hospital ◽  
Governmental Organization ◽  
Medical Division ◽  
Disease Case

Since the onset of the worst epidemic of Ebola virus disease in December 2013, 28,637 cases were reported as confirmed, probable, or suspected. Since the week of 3 January 2016, no more cases have been reported. The total number of deaths have amounted to 11,315 (39.5%). In developed countries, seven cases have been diagnosed: four in the United States, one in Spain, one in the United Kingdom, and one in Italy. On 20 July 2015, Italy was declared Ebola-free. On 9 May 2015, an Italian health worker came back to Italy after a long stay in Sierra Leone working for a non-governmental organization. Forty-eight hours after his arrival, he noticed headache, weakness, muscle pains, and slight fever. The following day, he was safely transported to the Infectious Diseases Unit of University Hospital of Sassari. The patient was hospitalized for 19 hours until an Italian Air Force medical division transferred him to Rome, to the Lazzaro Spallanzani Institute. Nineteen people who had contacts with the patient were monitored daily for 21 days by the Public Health Office of Sassari and none presented any symptoms. So far, neither vaccine nor treatment is available to be proposed on an international scale. Ebola is considered a re-emerging infectious disease which, unlike in the past, has been a worldwide emergency. This case study aimed to establish a discussion about the operative and logistic difficulties to be faced and about the discrepancy arising when protocols clash with the reality of facts.

scholarly journals Vaccines and Antibodies: Weapons in the Fight Against Ebola Virus

2021 ◽  
Vol 9 ◽  
Author(s):  
Patrice Debré ◽  
Marie Neunez ◽  
Michel Goldman
Keyword(s):  
Infectious Disease ◽  
Immune System ◽  
Infectious Diseases ◽  
Human Body ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
World Today ◽  
The World ◽  
Stimulation Of

Ebola virus disease is one of the deadliest infections in the world today. The microbe to blame is the Ebola virus. It has already caused numerous outbreaks in Africa, in the regions located south of the Sahara. This article describes the main characteristics of this infectious disease as well as the currently available treatments, namely vaccines and antibodies. Antibodies are produced by the human body when it is infected by a microbe. Antibodies can be collected from the blood of infected humans or animals and purified or manufactured in a laboratory to produce drugs. While vaccines have demonstrated their effectiveness in preventing infectious diseases, antibodies are effective in stopping the progression of several infectious diseases. In this article, you will discover that the stimulation of the immune system, either by the vaccine or by antibodies, is essential to tackle Ebola virus disease.

scholarly journals Pre-Ebola virus disease laboratory system and related challenges in Liberia

2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Stephen B. Kennedy ◽  
John B. Dogba ◽  
Christine L. Wasunna ◽  
Philip Sahr ◽  
Candace B. Eastman ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Ebola Virus ◽  
Virus Disease ◽  
Emerging Infectious Diseases ◽  
Health Facilities ◽  
Sub Saharan Africa ◽  
Ebola Virus Disease ◽  
Reference Laboratory ◽  
Laboratory System ◽  
Human Resource Capacity

Prior to the Ebola virus disease outbreak in Liberia, the laboratory system was duplicativefragmented and minimally coordinated. The National Reference Laboratory was conceptualisedto address the existing challenges by promoting the implementation of effective and sustainablelaboratory services in Liberia. However, in a resource-limited environment such as Liberiaprogress regarding the rebuilding of the health system can be relatively slow, while efforts tosustain the transient gains remain a key challenge for the Ministry of Health. In this paper, wedescribe the pre-Ebola virus disease laboratory system in Liberia and its prevailing efforts toaddress future emerging infectious diseases, as well as current Infectious diseases, all of whichare exacerbated by poverty. We conclude that laboratory and diagnostic services in Liberiahave encountered numerous challenges regarding its efforts to strengthen the healthcaredelivery system. These challenges include limited trained human resource capacity, inadequateinfrastructure, and a lack of coordination. As with most countries in sub-Saharan Africa, whencomparing urban and rural settings, diagnostic and clinical services are generally skewedtoward urban health facilities and private, faith-based health facilities. We recommend thatstructured policy be directed at these challenges for national institutions to develop guidelinesto improve, strengthen and sustain diagnostic and curative laboratory services to effectivelyaddress current infectious diseases and prepare for future emerging and re-emerging infectiousdiseases.

scholarly journals Educating Health Care Providers in Treatment of Patients With Ebola Virus Disease

2016 ◽  
Vol 36 (5) ◽  
pp. e8-e13 ◽  
Author(s):  
Ellen J. Eckes ◽  
Debbie Gutierrez ◽  
Ann Peterson ◽  
Melissa Hubbard ◽  
Kevin Barrett ◽  
...  
Keyword(s):  
Nursing Education ◽  
Infectious Diseases ◽  
Health Care Providers ◽  
Nursing Care ◽  
Ebola Virus ◽  
Virus Disease ◽  
Multidrug Resistant ◽  
Ebola Virus Disease ◽  
Expert Advice ◽  
Care Providers

Nurses manage patients with common infectious diseases by following institutional guidelines based on expert advice, evidence in the literature, and a wealth of experience. Today nurses are challenged to provide care to patients with multidrug-resistant organisms and virulent infectious diseases such as Ebola virus disease. Management of some patients with virulent infectious diseases occurs in the context of minimal experience with the pathogen, course of infection, diagnostics, nursing care, and treatment. Limited evidence exists in the US or international literature about direct nursing care of patients with virulent infectious diseases in the community, clinic, or hospital. Workplaces may have insufficient supplies, equipment, and knowledge of the management of patients with these diseases. At the National Institutes of Health Clinical Center in Bethesda, Maryland, nursing education strategies for enhanced experiential learning are used to prepare staff to care for patients with virulent infectious diseases, especially Ebola virus disease.

scholarly journals Bibliometric Analysis of Ebola Research Indexed in Web of Science and Scopus (2010-2020)

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Joseph Kawuki ◽  
Xiaojin Yu ◽  
Taha Hussein Musa
Keyword(s):  
Infectious Diseases ◽  
Bibliometric Analysis ◽  
Ebola Virus ◽  
Web Of Science ◽  
Democratic Republic Of Congo ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
African Countries ◽  
Double Blind ◽  
Effective Prevention

Background. Within the past decade, Africa has faced several recurrent outbreaks of Ebola virus disease (EVD), including the 2014-2016 outbreak in West Africa and the recent 2018-2020 Kivu outbreak in the Democratic Republic of Congo. The study thus aimed at quantifying and mapping the scientific output of EVD research published within 2010-2020 though a bibliometric perspective. Methods. EVD-related publications from 2010 to 2020 were retrieved from the Web of Science (WoS) and Scopus databases by using the keywords ‘Ebola’, ‘Ebola Virus Disease’, ‘Ebolas’, and ‘ebolavirus’. Biblioshiny software (using R-studio cloud) was used to categorise and evaluate authors’, countries’ and journals’ contribution. VOSviewer was used for network visualisation. Results. According to the used search strategy, a total of 3865 and 3848 EVD documents were published in WoS and Scopus, respectively. The average citation per document was 16.1 (WoS) and 16.3 (Scopus). The results show an overall increase in the publication trend within the study period. The leading countries in EVD research were the USA and UK, with over 100 papers in both databases, including Nigeria and South Africa. NIAID and CDC-USA were the most influential institutions, while “Infectious Diseases” and “Medicine” were the most decisive research fields. The most contributing authors included Feldmann H and Qiu XG with over 60 papers in each database, while Journal of Infectious Diseases was the most crucial journal. The most cited article was from Aylward et al. published in 2014, while recent years displayed a keyword focus on “double-blind”, “efficacy”, “ring vaccination” and “drug effect”. Conclusion. This bibliometric analysis provides an updated historical perspective of progress in EVD research and has highlighted the role played by various stakeholders. However, the contribution of African countries and institutions is not sufficiently reflected, implying a need for increased funding and focus on EVD research for effective prevention and control.

Pre-transfusion testing for Ebola virus disease patients in serious communicable infectious diseases hospitals in Tokyo: A cross-sectional study

2019 ◽  
Vol 25 (7) ◽  
pp. 489-493
Author(s):  
Naoya Sakamoto ◽  
Atsushi Kosaka ◽  
Akifumi Imamura ◽  
Fukumi Uchiyama-Nakamura ◽  
Sentaro Iwabuchi ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Ebola Virus ◽  
Virus Disease ◽  
Cross Sectional Study ◽  
Ebola Virus Disease ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Diminished Quality of Life among Women affected by Ebola

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Jessi Hanson ◽  
Alexis Decosimo ◽  
Megan Quinn
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Literature Review ◽  
Infectious Diseases ◽  
Psychosocial Stress ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Negative Experiences

This article analyzes data collected from Liberian women afflicted by the Ebola virus disease, survivors of the virus and noninfected persons living in Ebola-affected homes. This research is one of the first statistical analyses examining factors diminishing quality of life: negative experiences, stigma, and psychosocial symptoms among females affected by the virus after the outbreak. The research presents a thorough literature review, including research related to other infectious diseases like HIV/AIDS, to inform the gap in studies on Ebola’s effects on quality of life. Women who are Ebola virus disease survivors demonstrate significant differences in stigma and psychosocial stress when compared to their female peers. This article attempts to broaden understanding of the conditions and mental health of women affected by Ebola.

Treatment of ebola and other infectious diseases: melatonin “goes viral”

2020 ◽  
Vol 3 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Russel J Reiter ◽  
Qiang Ma ◽  
Ramaswamy Sharma
Keyword(s):  
Mortality Rate ◽  
Infectious Diseases ◽  
Hemorrhagic Shock ◽  
Safety Profile ◽  
Ebola Virus ◽  
Viral Infections ◽  
Virus Disease ◽  
Attractive Potential ◽  
Potential Treatment

This review summarizes published reports on the utility of melatonin as a treatment for virus-mediated diseases. Of special note are the data related to the role of melatonin in influencing Ebola virus disease. This infection and deadly condition has no effective treatment and the published works documenting the ability of melatonin to attenuate the severity of viral infections generally and Ebola infection specifically are considered. The capacity of melatonin to prevent one of the major complications of an Ebola infection, i.e., the hemorrhagic shock syndrome, which often contributes to the high mortality rate, is noteworthy. Considering the high safety profile of melatonin, the fact that it is easily produced, inexpensive and can be self-administered makes it an attractive potential treatment for Ebola virus pathology.  

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