Resistin levels and its relation with body mass index and hydrogen peroxide production in blood cells from diabetic periodontal patients

Objective: To investigate the associations between nutritional status and lipid profile with biomarkers of hemolysis and inflammation in sickle cell anemia, in addition to considering gender differences. Methods: This cross-sectional study analyzed nutritional, and biochemical data of pediatric patients carrying sickle cell anemia. Results: Vitamin A, apolipoprotein B, total cholesterol, low-density lipoprotein, and non-high-density lipoprotein cholesterol were lower in boys. Hemoglobin was significantly lower, and the white blood cells and lactate dehydrogenase were higher in boys. Body mass index, vitamin A, and triglycerides were associated with hemoglobin levels, while apolipoprotein A-I was associated with white blood cells and total bilirubin. Additionally, body mass index and vitamin A were associated with lactate dehydrogenase. Vitamin A showed significant predictive power in hemoglobin alteration and lactate dehydrogenase, while apolipoprotein A-I was able to predict high white blood cells values and total bilirubin. Conclusion: This study found in a pediatric population with sickle cell anemia that body mass index, vitamin A, triglycerides, and apolipoprotein A-I were associated with biomarkers of hemolysis and inflammation. Boys exhibited the greater nutritional deficit and severity of the disease.

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Positive Associations between Body Mass Index and Hematological Parameters, Including RBCs, WBCs, and Platelet Counts, in Korean Children and Adolescents

Children ◽

10.3390/children9010109 ◽

2022 ◽

Vol 9 (1) ◽

pp. 109

Author(s):

Hwal Rim Jeong ◽

Hae Sang Lee ◽

Young Suk Shim ◽

Jin Soon Hwang

Keyword(s):

Body Mass Index ◽

Children And Adolescents ◽

Body Mass ◽

Blood Cells ◽

Hematological Parameters ◽

Linear Regression Analysis ◽

Normal Weight ◽

Overweight And Obesity ◽

Korean Children ◽

Platelet Counts

We conducted this study to investigate the associations between hematological parameters and obesity in children and adolescents. The levels of hematological parameters (including white blood cells [WBCs], red blood cells [RBCs], hemoglobin [Hb], hematocrit [Hct], and platelets) of 7997 participants (4259 boys and 3738 girls) aged 10–18 years were recorded. The parameters were compared among participants with normal weight, overweight, and obesity. Significantly higher mean levels of WBCs (7.16 vs. 6.16 × 103/mm3, p < 0.001), RBCs (4.90 vs. 4.82 × 106/mm3, p < 0.001), Hb (14.07 vs. 13.99 g/dL, p < 0.05), Hct (42.31 vs. 41.91%, p < 0.001), and platelets (311.87 vs. 282.66 × 103/mm3, p < 0.001) were found in the obese than normal weight group, respectively, after adjusting for body mass index (BMI) and sex. BMI SDS had significant positive associations with the levels of WBCs (β = 0.275, p < 0.001), RBCs (β = 0.028, p < 0.001), Hb (β = 0.034, p < 0.001), Hct (β = 0.152, p < 0.001), and platelets (β = 8.372, p < 0.001) after adjusting for age, sex, and socioeconomic factors in a multiple linear regression analysis. A higher BMI was associated with elevated WBC, RBC, Hb, Hct, and platelet counts in children and adolescents. Because higher levels of hematological parameters are potential risk factors for obesity-related diseases, hematological parameters should be evaluated in obese children and adolescents.

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The relationship between the activates of antioxidant enzymes in red blood cells and body mass index in Iranian type 2 diabetes and healthy subjects

Journal of Diabetes & Metabolic Disorders ◽

10.1186/2251-6581-11-3 ◽

2012 ◽

Vol 11 (1) ◽

Cited By ~ 10

Author(s):

Ehsaneh Taheri ◽

Mahmoud Djalali ◽

Ahmad Saedisomeolia ◽

Ali Malekshahi Moghadam ◽

Abolghasem Djazayeri ◽

...

Keyword(s):

Type 2 Diabetes ◽

Body Mass Index ◽

Antioxidant Enzymes ◽

Red Blood Cells ◽

Body Mass ◽

Blood Cells ◽

Healthy Subjects ◽

The Relationship

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Higher donor body mass index is associated with increased hemolysis of red blood cells at 42‐days of storage: A retrospective analysis of routine quality control data

Transfusion ◽

10.1111/trf.16203 ◽

2020 ◽

Author(s):

Rosemary L. Sparrow ◽

Katherine A. Payne ◽

Geoffrey G. Adams

Keyword(s):

Body Mass Index ◽

Quality Control ◽

Red Blood Cells ◽

Retrospective Analysis ◽

Body Mass ◽

Blood Cells ◽

Control Data ◽

Quality Control Data ◽

Routine Quality Control

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Long working hours, anthropometry, lung function, blood pressure and blood-based biomarkers: cross-sectional findings from the CONSTANCES study

Journal of Epidemiology & Community Health ◽

10.1136/jech-2018-210943 ◽

2018 ◽

Vol 73 (2) ◽

pp. 130-135 ◽

Cited By ~ 5

Author(s):

Marianna Virtanen ◽

Linda Magnusson Hansson ◽

Marcel Goldberg ◽

Marie Zins ◽

Sari Stenholm ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Waist Circumference ◽

Body Mass ◽

Blood Cells ◽

White Blood Cells ◽

Working Hours ◽

Cross Sectional ◽

Long Working Hours ◽

Anthropometric Markers

BackgroundAlthough long working hours have been shown to be associated with the onset of cardiometabolic diseases, the clinical risk factor profile associated with long working hours remains unclear. We compared the clinical risk profile between people who worked long hours and those who reported being never exposed to long hours.MethodsA cross-sectional study in 22 health screening centres in France was based on a random population-based sample of 75 709 participants aged 18–69 at study inception in 2012–2016 (the CONSTANCES study). The data included survey responses on working hours (never, former or current exposure to long working hours), covariates and standardised biomedical examinations including anthropometry, lung function, blood pressure and standard blood-based biomarkers.ResultsAmong men, long working hours were associated with higher anthropometric markers (Body Mass Index, waist circumference and waist:hip ratio), adverse lipid levels, higher glucose, creatinine, white blood cells and higher alanine transaminase (adjusted mean differences in the standardised scale between the exposed and unexposed 0.02–0.12). The largest differences were found for Body Mass Index and waist circumference. A dose–response pattern with increasing years of working long hours was found for anthropometric markers, total cholesterol, glucose and gamma-glutamyltransferase. Among women, long working hours were associated with Body Mass Index and white blood cells.ConclusionIn this study, men who worked long hours had slightly worse cardiometabolic and inflammatory profile than those who did not work long hours, especially with regard to anthropometric markers. In women, the corresponding associations were weak or absent.

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