scholarly journals Three-Dimensional sp2 Carbon-Linked Covalent Organic Frameworks for Bioresponsive Fluorescence Imaging

2021 ◽  
Author(s):  
Li Liao ◽  
Zerong Zhang ◽  
Xinyu Guan ◽  
Hui Li ◽  
Yaozu Liu ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Drug Carrier ◽  
Three Dimensional ◽  
Porous Polymers ◽  
High Tech ◽  
Covalent Organic Frameworks ◽  
Formation Reaction ◽  
Light Emitting ◽  
Fluorescent Materials ◽  
Fluorescent Stains

<a>Three-dimensional (3D) covalent organic frameworks (COFs) are crystalline porous polymers with potential in numerous high-tech applications, but the linkages involved in their synthesis are still rather limited. Herein we report the first </a><a>case of 3D sp<sup>2</sup> carbon-linked COFs</a> fabricated by the formation reaction of C=C bonds and their application in bioresponsive fluorescence imaging. These new COFs, namely JUC-580 and JUC-581, showed high stability and excellent light-emitting properties in solid state and dispersed in various solvents. <a>Furthermore, we investigated </a>the potential application of JUC-581 for a drug carrier combined with bioresponsive fluorescence imaging. The results indicated that 3D sp<sup>2</sup> carbon-linked COFs are not only potential drug-loaded and sustained release materials but also promising cell fluorescent stains. This study expands the structural categories of 3D COFs based on different linkages, and promotes their prospective applications for biomedicine and fluorescent materials.

scholarly journals Three-Dimensional sp2 Carbon-Linked Covalent Organic Frameworks for Bioresponsive Fluorescence Imaging

2021 ◽  
Author(s):  
Li Liao ◽  
Zerong Zhang ◽  
Xinyu Guan ◽  
Hui Li ◽  
Yaozu Liu ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Drug Carrier ◽  
Three Dimensional ◽  
Porous Polymers ◽  
High Tech ◽  
Covalent Organic Frameworks ◽  
Formation Reaction ◽  
Light Emitting ◽  
Fluorescent Materials ◽  
Fluorescent Stains

<a>Three-dimensional (3D) covalent organic frameworks (COFs) are crystalline porous polymers with potential in numerous high-tech applications, but the linkages involved in their synthesis are still rather limited. Herein we report the first </a><a>case of 3D sp<sup>2</sup> carbon-linked COFs</a> fabricated by the formation reaction of C=C bonds and their application in bioresponsive fluorescence imaging. These new COFs, namely JUC-580 and JUC-581, showed high stability and excellent light-emitting properties in solid state and dispersed in various solvents. <a>Furthermore, we investigated </a>the potential application of JUC-581 for a drug carrier combined with bioresponsive fluorescence imaging. The results indicated that 3D sp<sup>2</sup> carbon-linked COFs are not only potential drug-loaded and sustained release materials but also promising cell fluorescent stains. This study expands the structural categories of 3D COFs based on different linkages, and promotes their prospective applications for biomedicine and fluorescent materials.

scholarly journals The Macroscopic Covalent Organic Framework Architectures for Water Remediation

2021 ◽  
Author(s):  
Abdul Khayum Mohammed ◽  
Dinesh Shetty
Keyword(s):  
Organic Molecules ◽  
Three Dimensional ◽  
Water Remediation ◽  
Porous Polymers ◽  
Covalent Organic Frameworks ◽  
Dynamic Covalent Chemistry ◽  
Covalent Organic Framework ◽  
Synthetic Strategy ◽  
Organic Framework

Covalent organic frameworks (COFs) are two- (2D) or three-dimensional (3D) crystalline and porous polymers constructed from organic molecules with various symmetries. The reticular synthetic strategy and the dynamic covalent chemistry...

scholarly journals Performance of GaN-Based LEDs with Nanopatterned Indium Tin Oxide Electrode

2016 ◽  
Vol 2016 ◽  
pp. 1-7
Author(s):  
Zhanxu Chen ◽  
Wenjie Liu ◽  
Wei Wan ◽  
Gengyan Chen ◽  
Yongzhu Chen ◽  
...  
Keyword(s):  
Tin Oxide ◽  
Indium Tin Oxide ◽  
Ohmic Contacts ◽  
Three Dimensional ◽  
Light Output ◽  
Light Extraction Efficiency ◽  
Experimental Result ◽  
Indium Tin Oxide Electrode ◽  
Light Emitting ◽  
Ito Electrode

The indium tin oxide (ITO) has been widely applied in light emitting diodes (LEDs) as the transparent current spreading layer. In this work, the performance of GaN-based blue light LEDs with nanopatterned ITO electrode is investigated. Periodic nanopillar ITO arrays are fabricated by inductive coupled plasma etching with the mask of polystyrene nanosphere. The light extraction efficiency (LEE) of LEDs can be improved by nanopatterned ITO ohmic contacts. The light output intensity of the fabricated LEDs with nanopatterned ITO electrode is 17% higher than that of the conventional LEDs at an injection current of 100 mA. Three-dimensional finite difference time domain simulation matches well with the experimental result. This method may serve as a practical approach to improving the LEE of the LEDs.

Simple fabrication of a three-dimensional porous polymer film as a diffuser for organic light emitting diodes

Nanoscale ◽  
2014 ◽  
Vol 6 (23) ◽  
pp. 14446-14452 ◽  
Author(s):  
Byung Wan Lim ◽  
Min Chul Suh
Keyword(s):  
Polymer Film ◽  
Spin Coating ◽  
Three Dimensional ◽  
Cost Effective ◽  
Porous Polymer ◽  
Organic Light Emitting Diodes ◽  
Coating Process ◽  
Light Emitting ◽  
Organic Light ◽  
Ultrasonic Humidifier

We have investigated a simple and cost-effective fabrication method for a porous polymer film employing the spin-coating process during continuous supply of water droplets by an ultrasonic humidifier.

Three-Dimensional Covalent Organic Frameworks with hea Topology

2021 ◽  
Author(s):  
Zonglong Li ◽  
Li Sheng ◽  
Chouhung Hsueh ◽  
Xiaolin Wang ◽  
Hao Cui ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Covalent Organic Frameworks

Lab-on-a-Chip System for Developing and Fluorescence Imaging a Three-Dimensional Model of Pancreatic Islets Under Flow Conditions

2021 ◽  
Vol MA2021-01 (55) ◽  
pp. 1396-1396
Author(s):  
Zbigniew Brzozka ◽  
Patrycja Sokołowska ◽  
Kamil Zukowski ◽  
Justyna Janikiewicz ◽  
Ekzbieta Jastrzebska ◽  
...  
Keyword(s):  
Pancreatic Islets ◽  
Fluorescence Imaging ◽  
Three Dimensional ◽  
Lab On A Chip ◽  
Dimensional Model ◽  
Flow Conditions ◽  
Three Dimensional Model

scholarly journals Diatoms Green Nanotechnology for Biosilica-Based Drug Delivery Systems

Pharmaceutics ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 242 ◽  
Author(s):  
Monica Terracciano ◽  
Luca De Stefano ◽  
Ilaria Rea
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Low Cost ◽  
Release Kinetics ◽  
Drug Carrier ◽  
Drug Loading ◽  
Three Dimensional ◽  
Delivery Systems ◽  
Diatom Frustule ◽  
Artificial Environment

Diatom microalgae are the most outstanding natural source of porous silica. The diatom cell is enclosed in a three-dimensional (3-D) ordered nanopatterned silica cell wall, called frustule. The unique properties of the diatom frustule, including high specific surface area, thermal stability, biocompatibility, and tailorable surface chemistry, make diatoms really promising for biomedical applications. Moreover, they are easy to cultivate in an artificial environment and there is a large availability of diatom frustules as fossil material (diatomite) in several areas of the world. For all these reasons, diatoms are an intriguing alternative to synthetic materials for the development of low-cost drug delivery systems. This review article focuses on the possible use of diatom-derived silica as drug carrier systems. The functionalization strategies of diatom micro/nanoparticles for improving their biophysical properties, such as cellular internalization and drug loading/release kinetics, are described. In addition, the realization of hybrid diatom-based devices with advanced properties for theranostics and targeted or augmented drug delivery applications is also discussed.

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