Combined oral contraceptives with natural estrogen and sexual function: the optimal method of contraception for women of different ages

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (1) ◽  
pp. 33-37
Author(s):  
Svetlana V Yureneva ◽  
Liliia M Ilina
Keyword(s):  
Quality Of Life ◽  
Beneficial Effect ◽  
Sexual Function ◽  
Oral Contraceptives ◽  
Well Being ◽  
Reproductive Period ◽  
Estradiol Valerate ◽  
Optimal Method ◽  
Combined Oral Contraceptives

Background. Combined oral contraceptives (COCs) are the most common method of prevention of unwanted pregnancies in women from the early reproductive period to perimenopause, therefore their impact on quality of life, sexual function and general well-being remains the subject of active discussion. Some studies revealed various manifestations of sexual dysfunction in patients receiving COCs, therefore such questions, as well as the advantages / disadvantages of individual components (their type and dose) of drugs, are of interest to the clinician. Aim. Assess mechanisms of influence of COCs on female sexual function. Materials and methods. In order to write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, elibrary, etc.) for the last 2-15 years. Relevant articles from the peer-reviewed literature were included. Results. Many studies proved a beneficial effect of estradiol valerate (E2V) which is estrogen identical to natural one in a combination with dienogest (DNG) which is 4th generation progestin in a dynamic dosing regimen on quality of life and sexual function. This beneficial effect is achieved due to combined effects of both components of the drug as well as its reception mode. Conclusion. The combination of estradiol valerate (E2V) which is estrogen identical to natural one with dienogest (DNG) which is 4th generation progestin may be the optimal method of contraception for women of any age, including the young, with decreased libido while taking other COCs.

Sexual Dysfunction in Patients with Neuropsychiatric Disorders: Challenges and Opportunities

CNS Spectrums ◽  
2006 ◽  
Vol 11 (S9) ◽  
pp. 4-4
Author(s):  
Barry Gidal ◽  
John J. Barry
Keyword(s):  
Quality Of Life ◽  
Sexual Dysfunction ◽  
Adverse Effects ◽  
Sexual Function ◽  
Healthcare Providers ◽  
Well Being ◽  
Sexual Disorders ◽  
Functional Impairments ◽  
The Impact

Quality-of-life issues in healthcare have come to be of paramount importance for a population that increasingly expects healthcare not only to treat major illnesses but also to optimize normal levels of physical and psychosocial functioning and overall well-being. Healthcare providers have also increasingly appreciated the impact that adverse effects of treatment can have on quality of life, as well as on compliance with and the effectiveness of treatment.Many functional impairments and adverse treatment effects take the form of clinical complaints that patients and caregivers typically report to their healthcare providers without prompting. Other adverse effects are not so obviously clinical or treatment-related, and patients may not be inclined or may even be reluctant to bring them up when talking with the provider. Impairment of sexual function is a problem of this kind.Sexual dysfunction appears to be common and frequently underrecognized in certain patient populations. For example, it has been estimated that 25% to 63% of women and 10% to 52% of men with epilepsy have some form of sexual dysfunction, yet in clinical reviews of sexual disorders, epilepsy is not listed as one of the medical conditions commonly associated with impaired sexual function.

Effects of estradiol valerate and dienogest on quality of life and sexual function according to age.

2014 ◽  
Vol 30 (12) ◽  
pp. 925-928 ◽  
Author(s):  
Costantino Di Carlo ◽  
Virginia Gargano ◽  
Nicoletta De Rosa ◽  
Giovanni Antonio Tommaselli ◽  
Stefania Sparice ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Function ◽  
Estradiol Valerate

Lifestyle and outcomes after gastrointestinal cancer: A prospective cohort study (LOGIC).

2018 ◽  
Vol 36 (7_suppl) ◽  
pp. 180-180
Author(s):  
Marissa Barbara Savoie ◽  
Katherine Van Loon ◽  
Angela Laffan ◽  
Andrea Grace Bocobo ◽  
Li Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cohort Study ◽  
Sexual Function ◽  
Cancer Recurrence ◽  
Well Being ◽  
Fear Of Cancer Recurrence ◽  
Psychological Well Being ◽  
Gi Cancer ◽  
Gi Cancers

180 Background: The number of individuals living after a diagnosis of gastrointestinal (GI) cancer is increasing. Emerging data suggest modifiable lifestyle factors impact survival after colorectal cancer (CRC), however very little is known about survivorship in other GI cancers. Given the common thread of multimodality therapy among many GI cancer survivors, there is a paucity of data on sexual function, fertility, anxiety/depression, changes in comorbidities, and quality of life after cancer treatment. Additionally, existing cohort studies of GI survivors are primarily European, and further data are needed from survivor populations in the US . Methods: Patients of the University of California, San Francisco GI Oncology Survivorship Clinic who are designated disease-free are recruited by mail or in clinic. We send secure online questionnaires to participants every six months for five years and annually thereafter. At varying intervals, questionnaires solicit sociodemographics, diet, physical activity, fertility, medical and smoking history, fear of cancer recurrence, sexual health, quality of life, psychological well-being, and sleep quality. Pathoclinical disease characteristics, treatment, and recurrence status are abstracted from the medical record at baseline and updated annually. Results: Between February and August 2017, 111 patients were enrolled; 68% of participants completed ≥1 and 57% completed all baseline questionnaires. Most patients had a history of colon cancer (52%, n = 58) or rectal cancer (31%, n = 34). Other diseases include: anal cancer (12%, n = 13), gastrointestinal stromal tumor (3%, n = 3), and other GI cancers (3%, n = 3). Fifty-eight percent of patients were female, 76% identified as white and median age at diagnosis was 55 (range 20-81). Median time from initial GI cancer diagnosis to study entry was 27 months. Following the initial recruitment wave of established patients, the average rate of enrollment is ~3 patients/week. Conclusions: Results from this ongoing cohort study will improve our understanding of modifiable risk factors for GI cancer recurrence and key survivorship issues related to psychological well-being, sexual function, fertility management, and quality of life.

Opportunities of treatment for primary dysmenorrhea in young women. Case report

GYNECOLOGY ◽  
2021 ◽  
Vol 23 (3) ◽  
Author(s):  
Nataliya A. Buralkina ◽  
Zalina K. Batyrova ◽  
Zaira K. Kumykova
Keyword(s):  
Quality Of Life ◽  
Oral Contraceptives ◽  
Young Women ◽  
Pain Syndrome ◽  
Primary Dysmenorrhea ◽  
Combined Oral Contraceptives ◽  
Common Causes ◽  
Effective Use ◽  
Safe Treatment Option

Primary dysmenorrhea is one of the most common causes of pelvic pain in women. It can reduce quality of life and interfere with daily activities. The use of combined oral contraceptives in young women with primary dysmenorrhea is an effective and safe treatment option. The article presents a clinical case of the effective use of combined oral contraceptives containing drospirenone in a young woman with primary dysmenorrhea and severe pain syndrome, which is not relieved by analgesics and antispasmodics and significantly reduces the patient's quality of life.

scholarly journals Effects of oral contraceptives on the quality of life of women with polycystic ovary syndrome: a crossover randomized controlled trial

2020 ◽  
Author(s):  
Mina Amiri ◽  
Fatemeh Nahidi ◽  
Razieh Bidhendi-Yarandi ◽  
Davood Khalili ◽  
Maryam Tohidi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Polycystic Ovary Syndrome ◽  
Sexual Function ◽  
Oral Contraceptives ◽  
Polycystic Ovary ◽  
Menstrual Disorders ◽  
Ovary Syndrome ◽  
Randomized Controlled ◽  
Self Image

Abstract Background and objective A limited number of studies have evaluated the effects of oral contraceptives (OCs) on the quality of life (QOL) of polycystic ovary syndrome (PCOS) patients. This study aimed to compare the effects of using OCs containing levonorgestrel (LNG) and those containing desogestrel (DSG), cyproterone acetate (CPA) or drospirenone (DRSP) for 6 months on the QOL with PCOS. Methods In this crossover randomized controlled 6-arm trial, 200 eligible patients with PCOS scheduled for OC therapy were randomly assigned to one of the 6 study arms. All 6 arms include two 6-month treatment periods, one period with OCs containing LNG, and the other with each of the 3 OCs containing DSG, CPA, or DRSP. Outcomes of interest were the total score of QOL and its domains, which were assessed using a specific and valid health‐related quality of life questionnaire for PCOS, which is consisted of six domains, including psychosocial–emotional, self-image, fertility, sexual function, hirsutism, and obesity– menstrual disorders.Results Finally, a total of 88 patients were analyzed for this study. The results showed that use of OCs containing DSG, CPA, and DRSP for 3 months was not associated with significant differences in the total scores of QOL compared to those OCs containing LNG, whereas, after 6 months of treatment, patients treated with OCs containing CPA had more improvements in their total scores of QOL, in comparison to OCs containing LNG (P < 0.042). We found no significant differences in QoL domains, including psychosocial–emotional, self-image, fertility, sexual function, hirsutism, and obesity-menstrual disorders after 3- 6 months of treatment with DSG, CPA, or DRSP, compared to LNG. The sequence and period effects were not significant in any of the analyses at 3 and 6 months of treatment. The carry-over effect was not significant for most outcomes assessed. Conclusions This crossover study demonstrated non-inferiority of OCs with newer generation progestins on different domains of QOL, in comparison with older compounds, although usage of products containing CPA was significantly associated with more improvement in total QOL of PCOS patients, compared to those containing LNG after 6-month of treatment. Clinical Trial Registration Number: IRCT201702071281N2.

scholarly journals QUALITY OF LIFE AMONG PATIENTS UNDERGOING HAEMODIALYSIS IN JAKARTA, INDONESIA

2019 ◽  
Vol 19 (2) ◽  
pp. 29-37
Author(s):  
Diana Laila Ramatillah ◽  
Syed Azhar Syed Sulaiman ◽  
Amer Hayat Khan
Keyword(s):  
Quality Of Life ◽  
Patient Satisfaction ◽  
Cognitive Function ◽  
Kidney Disease ◽  
Sexual Function ◽  
Physical Functioning ◽  
Standard Form ◽  
Well Being ◽  
Role Emotional

Haemodialysis is a continuous treatment provided to patients with chronic kidney disease as a replacement for renal function. It is important to assess the quality of life among these patients. The aim of this study was to evaluate quality of life among patients on haemodialysis using an Indonesian version of the KDQoL-SF24 questionnaire. This is a cohort observational study that included 145 haemodialysis patients in a haemodialysis centre in Jakarta, Indonesia. A translated and validated version of the KDQoL-SF24 was used in this survey. The participants in this study had lower mean scores than the standard form in the following 6 components: burden of kidney disease (44.22±33.23), cognitive function (74.94±20.32), sleep (57.07±24.15), patient satisfaction (60.11±18.56), role-physical (26.21±44.01), emotional well-being (69.19±24.25) and role-emotional (40.69±49.18). A significant relationship was found between sexual function, physical functioning, role emotional and age among haemodialysis patients (P <0.05). Based on the overall health rating from the KDQoL-SF24, the mean and standard deviation for the 21- to 30-year-old age group was lower than the standard form. The burden of kidney disease, cognitive function, sleep, patient satisfaction, role-physical, emotional well-being and role-emotional component scores were low for haemodialysis patients in Indonesia compared to the standard form. Additionally, age significantly affected sexual function, physical functioning and role-emotional.

scholarly journals Effectiveness of Physical Therapy in Addressing Sexual Dysfunction in Individuals with Multiple Sclerosis: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Arpita Gopal ◽  
Rebecca Sydow ◽  
Valerie Block ◽  
Diane D. Allen
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Physical Therapy ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Pelvic Floor ◽  
Sexual Satisfaction ◽  
Well Being ◽  
Current Evidence

Abstract Background: Individuals with multiple sclerosis (MS) frequently report sexual dysfunction, a condition that may result in low sexual satisfaction and decreased quality of life. Although sexual dysfunction is usually treated pharmacologically, physical therapists, especially those trained in pelvic floor physical therapy (PT), are well-equipped to address a variety of impairments that contribute to poor sexual function. The current evidence for effectiveness of PT interventions in improving sexual dysfunction, sexual satisfaction, and the emotional well-being aspect of quality of life was analyzed. Methods: The PubMed, CINAHL, and PEDro databases were searched through December 2019. Articles were included if participants had a clinical diagnosis of MS, reported sexual dysfunction or pain with intercourse, and had an intervention within the PT scope that addressed sexual dysfunction. Means and SDs were extracted from each study independently by two authors. Effect sizes (d) and 95% CIs were calculated within and across studies. Results: Eight studies met the inclusion criteria. Combined effects were significant and large across six studies for sexual function (d = 0.82, 95% CI, 0.57–1.06), moderate across seven studies for sexual satisfaction (d = 0.65, 95% CI, 0.43–0.87), and moderately large across two studies for emotional well-being (d = 0.78, 95% CI, 0.17–1.40). Between-group differences reached significance for sexual satisfaction (d = 0.29, 95% CI, 0.03–0.55). Conclusions: Sexual function, sexual satisfaction, and emotional well-being can all be effectively addressed with various PT interventions. Highly effective interventions included pelvic floor muscle training and mindfulness. Future research should compare PT interventions with non-PT controls to determine best practice in this population.

Quality of life in women of late reproductive age with infertility and endometrial pathology

2017 ◽  
pp. 118-121
Author(s):  
S.M. Korniyenko ◽  
Keyword(s):  
Quality Of Life ◽  
Depressive Disorders ◽  
Well Being ◽  
Reproductive Period ◽  
Reproductive Age ◽  
Life Assessment ◽  
Infertile Women ◽  
Endometrial Pathology ◽  
Fertile Women

Research has shown that infertile women are less satisfied with their lives than fertile women, as their mental, communicative, sexual and emotional well-being is undergoing a number of changes, especially in the late reproductive period when the proportion increases anxiety and depressive disorders. The objective: сompare the quality of life parameters in infertile and fertile women of late reproductive age with endometrial pathology. Patients and methods. The study included 237 women 35–44 years with different clinical forms of endometrial pathology. A questionnaire health SF-36 is used for studying the quality of life. Results. The study of quality of life showed that patients with infertility compared with fertile women significantly higher assessed and psychological (p<0.008) and the physical component of their health (p<0.02), showed the greatest difference in emotional functioning (p<0.002). It was revealed that the longer the sterility, the worse the patients rated their physical functioning (с=-0.32, p<0.001) and mental health (с=-0.25, p<0.02), and the higher their overall health satisfaction (с=0.28, p<0.004).A subjective satisfaction with the physical and mental state is assessed. It was found that the age lowers the quality of life assessment more than a period of infertility. According to data obtained in the study of quality of life does not depend from infertility factors, but is largely determined by the presence of children. Conclusions. It is concluded that the quality of life of secondary infertile women closest to the profile of fertile women; patient late reproductive age with infertility and endometrial pathology more satisfied with their lives than fertile women with endometrial pathology similar age. Key words: endometrial pathology, late reproductive period, infertility, quality of life.

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