scholarly journals GC-MS ANALYSIS OF BIO-ACTIVE COMPOUNDS FROM THE ETHANOLIC EXTRACT OF BALIOSPERMUM MONTANUM (WILD.) MUELL. ARG.

2018 ◽  
Vol 5 (1) ◽  
pp. 42-45
Author(s):  
Reshma K ◽  
Baluprakash T ◽  
Abdul Kaffoor H ◽  
Venkatachalapathi A ◽  
Arumugasamy K
Keyword(s):  
Methyl Ester ◽  
Medicinal Plant ◽  
Bioactive Compounds ◽  
Mass Spectra ◽  
Octadecadienoic Acid ◽  
Acid Methyl Ester ◽  
Ethanolic Extract ◽  
Acid Methyl ◽  
Pharmacological Studies ◽  
Phytochemical Compounds

Baliospermum montanum (Wild.) Muell. Arg., (Euphorbiaceae) is a well known medicinal plant which is used in treatment of various diseases. The present study was focussed on the separation and investigation of the phytochemical compounds from ethanolic extract by GC-MS technique. The mass spectra of thecompounds found in the extract were matched with the National Institute of Standards and Technology (NIST) library. The ethanolic extract revealed the presence of 30 bioactive compounds. The major and minor phytochemical compounds are 2,15-Dithia[3](9,10)anthracenol[3](2,6)pyridinophane,1,2,3,4-tetrahydro showed the highest peak 9.32% followed by phytol-9.08%, Neophytadiene-7.38%, 8,11-Octadecadienoic acid, methyl ester (CAS)-7.06%, 4-ethyl-6-[2-(methoxycarb onyl)ethenyl]-7-[2-(methoxycarbonyl)ethyl]1,3,5,8-tetramethyl-2-vinylporphyrin-6.72%, 2-pentafluorophenylpropanal-6.43%,4,4'-Isopropylidene-bis-(2-cyclo hexyl phenol)-5.91% etc.. Further pharmacological studies are needed to find out the medicinal aspect of these compounds.

scholarly journals GC-MS ANALYSIS PROFILE AND BIOACTIVE COMPONENTS OF FLOWERS OF Bergenia ciliata, A WEED OF ROCK CREVICES

2021 ◽  
Vol 27 (4) ◽  
pp. 527-535
Author(s):  
Malik F. H. Ferdosi ◽  
Iqra Haider Khan ◽  
Arshad Javaid ◽  
Hafiz M. Saeed ◽  
Ifrayeem Butt ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Octadecadienoic Acid ◽  
Acid Methyl Ester ◽  
Literature Survey ◽  
Pentadecanoic Acid ◽  
Bioactive Components ◽  
Hexadecanoic Acid ◽  
Acid Methyl ◽  
Ms Analysis ◽  
Hexanedioic Acid

Bergenia ciliata is a weed of hilly areas of Pakistan that generally grows in rock crevices. In the present study, flowers of this weeds were collected from Murree. The dried flowers were extracted in methanol and subjected to GC-MS analysis that showed 7 compounds in it. The predominant compound was hexanedioic acid, bis(2-ethylhexyl) ester (48.88%) followed by γ-sitosterol (22.56%). Moderately occurring compound was cyclohexane, 1,3,5-triphenyl- (12.87%). The remaining compounds namely n-hexadecanoic acid (4.97%), pentadecanoic acid, 14-methyl-, methyl ester (3.77%), 9,12-octadecadienoic acid, methyl ester, (Z,Z)-  (2.94%) and 9,12,15-octadecatrienoic acid, methyl ester, (Z,Z,Z)- (2.92%) were categorized as less abundant compounds. Literature survey indicated that these compounds possess antimicrobial, larvicidal, anti-inflammatory, anticancer and/or antidiabetic properties.

scholarly journals BIOCHEMICAL PROFILE OF Calotropis procera FLOWERS

2021 ◽  
Vol 27 (3) ◽  
pp. 341-349
Author(s):  
Malik Fiaz Hussain Ferdosi ◽  
Iqra Haider Khan ◽  
Arshad Javaid ◽  
Ayesha Munir
Keyword(s):  
Methyl Ester ◽  
Octadecadienoic Acid ◽  
Octadecenoic Acid ◽  
Acid Methyl Ester ◽  
Calotropis Procera ◽  
Biochemical Profile ◽  
Hexadecanoic Acid ◽  
Flower Extract ◽  
Acid Methyl ◽  
Peak Areas

Calotropis procera is a medicinal weed of family Asclepiadaceae. This study was carried out to explore the biochemical profile of C. procera flowers collected from Southern Punjab region of Pakistan. Methanolic flower extract of C. procera was subjected to GC-MS analysis. There were 30 compounds identified in this extract. The predominant compound was γ-sitosterol with 15.39% peak area. Other abundantly occurring compounds included stigmasterol (9.22%), 9,12-octadecadienoic acid (Z,Z)-, methyl ester (9.01%), campesterol (8.63%), α-amyrin acetate (8.25%), β-amyrin (8.09%), hexadecanoic acid, methyl ester (7.91%), 11-octadecenoic acid, methyl ester (6.15%), and 2-methoxy-4-vinylphenol (5.66%). Moderately abundant compounds included nonacos-1-ene (2.83%), methyl stearate (1.57%), pentacosane (1.44%), phytol (1.33%), heptacos-1-ene (1.20%), heneicosane (1.19%), and 1-hexacosene (1.09%). The remaining less abundant compounds were present with peak areas less than 1%. Literature survey showed that the major compounds identified in the flower extract of C. procera possess various bioactivities including antidiabetic, anticancer, antihyperglycemic, antioxidant, antimicrobial and anti-inflamatory.

Mass spectra of bile acid methyl ester acetate derivatives

1978 ◽  
Vol 13 (7) ◽  
pp. 402-409 ◽  
Author(s):  
Jerry Ray Dias ◽  
Bahman Nassim
Keyword(s):  
Bile Acid ◽  
Methyl Ester ◽  
Mass Spectra ◽  
Acid Methyl Ester ◽  
Acid Methyl

N-Acetylborrelidin B: a new bioactive metabolite from Streptomyces mutabilis sp. MII

2018 ◽  
Vol 73 (1-2) ◽  
pp. 49-57 ◽  
Author(s):  
Abdelaaty Hamed ◽  
Ahmed S. Abdel-Razek ◽  
Marcel Frese ◽  
Daniel Wibberg ◽  
Atef F. El-Haddad ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Methyl Ester ◽  
Bioactive Compounds ◽  
Screening Program ◽  
Acid Methyl Ester ◽  
In Vitro Cytotoxicity ◽  
Cervix Carcinoma ◽  
Nmr Studies ◽  
Acid Methyl

AbstractIn the course of our screening program for new bioactive compounds, a naturally new 18-membered macrolide antibiotic,N-acetylborrelidin B (1) along with borrelidin (2) were obtained from the marineStreptomyces mutabilissp. MII. The strain was isolated from a sediment sample collected in the Red Sea at the Hurghada Coast and characterized taxonomically. Additional nine diverse bioactive compounds were reported: 6-prenyl-indole-3-acetonitrile (3), sitosteryl-3β-d-glucoside, campesterol, ferulic acid, linoleic acid methyl ester, linoleic acid,N-acetylanthranilic acid, indole 3-acetic acid methyl ester, indole 3-carboxylic acid, and adenosine. Structure1was confirmed by in-depth NMR studies and by mass spectra, and comparison with related literature data. The antimicrobial activity of the strain extract and compounds1and2were studied using a panel of pathogenic microorganisms. The in vitro cytotoxicity of compounds1and2as well as the crude extract were tested against the human cervix carcinoma cell line (KB-3-1).

scholarly journals Bioactive Variability and In Vitro and In Vivo Antioxidant Activity of Unprocessed and Processed Flour of Nine Cultivars of Australian lupin Species: A Comprehensive Substantiation

Antioxidants ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 282 ◽  
Author(s):  
Kishor Mazumder ◽  
Afia Nabila ◽  
Asma Aktar ◽  
Asgar Farahnaky
Keyword(s):  
Antioxidant Activity ◽  
Methyl Ester ◽  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Acid Methyl Ester ◽  
Heat Processing ◽  
Acid Methyl ◽  
Ms Analysis

The aim of this present investigation was to analyze bioactive compounds, as well as demonstrate the antioxidant activities of nine cultivars of Australian lupin species accompanied by observing the effect of domestic heat processing on their antioxidant activities adopting in vivo and in vitro approaches. Gas chromatography mass spectroscopy (GC-MS) analysis was performed for profiling bioactive compounds present in lupin cultivars. Multiple assay techniques involving quantification of polyphenolics, flavonoids and flavonol, electron transfer (ET) based assay, hydrogen atom transfer (HAT)-based assay and in vivo assays were performed. The major compounds found were hexadecanoic acid methyl ester, 9,12-octadecadienoic acid methyl ester, methyl stearate, lupanine,13-docosenamide and 11-octadecenoic acid (Z)- methyl ester. Mandelup was found to show excellent antioxidant activity. Moreover, Jurien, Gunyidi and Barlock had strong antioxidant activity. Both positive and negative impacts of heat processing were observed on antioxidant activity. Heating and usage of excess water during processing were the key determinants of loss of antioxidants. Negligible loss of antioxidant activity was observed in most of the assays whereas inhibition of both lipid peroxidation (33.53%) and hemolysis of erythrocytes (37.75%) were increased after processing. In addition, in vitro and in vivo antioxidant assays are found to show statistically significant (* p < 0.05 and ** p < 0.01) results, which are supported by the presence of a number of antioxidant compounds in GC-MS analysis.

scholarly journals Bioassay-guided Identification of Bioactive Compounds from Senna alata L. against Methicillin-resistant Staphylococcus aureus

2021 ◽  
Author(s):  
Suwaiba Muhammad Ladan ◽  
Yusuf Wada ◽  
Mustapha Mohammed ◽  
Sani Ibrahim ◽  
Kabir Musa Yusuf ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methyl Ester ◽  
Bioactive Compounds ◽  
Diethyl Ether ◽  
Octadecenoic Acid ◽  
Acid Methyl Ester ◽  
Public Health Problem ◽  
Methicillin Resistant ◽  
Acid Methyl ◽  
Senna Alata

Senna alata (Linn) Roxb. plant is widely used to manage various infections in folkloric medicine. Methicillin-resistant Staphylococcus aureus (MRSA) infection continues to be a major global public health problem. This study aims to investigate the bioactive components of S. alata leaves active against MRSA. The leaves of S. alata were sequentially extracted and fractionated using standard methods and screened for activities against MRSA. The diethyl ether active thin layer chromatography (TLC) spot was subjected to infrared (IR) and gas chromatography-mass spectroscopic (GC-MS) studies. The aqueous extract and diethyl ether fraction of S. alata leaves elicited the highest activity against the MRSA. The GC-MS analysis of the fraction produced 15 eluates; only the sub-fraction 13 was effective. The TLC analysis of the sub-fraction 13 revealed three spots; only the second spot produced activity. The GC-MS result of the spot showed six peaks. The spectral results for peak 3 match the data from the IR study suggestive of 9-octadecenoic acid methyl ester. Senna alata leaves possess bioactive compounds closely related to 9-octadecenoic acid methyl ester with potent antibacterial activity against MRSA.

scholarly journals Characterization of Bioactive Sesquiterpenes, Organic Acids and Their Derivatives from the Leaves of Psidium guajava Linn

2014 ◽  
pp. 456-467
Author(s):  
Okenwa U. Igwe ◽  
T. Abii
Keyword(s):  
Mass Spectrometry ◽  
Methyl Ester ◽  
Octadecenoic Acid ◽  
Acid Methyl Ester ◽  
Psidium Guajava ◽  
Gas Chromatography Mass Spectrometry ◽  
Hexadecanoic Acid ◽  
Acid Methyl ◽  
Phytochemical Compounds

The isopropanolic extract of the leaves of Psidium guajava Linn was analyzed by Gas chromatography-mass spectrometry (GC-MS). Fourteen different phytochemical compounds have been characterized, including 1, 3, 3-trimethyl-2-oxabicyclo [2.2.2] octane, (2.06%), 4, 11, 11-trimethyl-bicyclo [7.2.0] undec-4-ene (6.26%), (E,E,E)-2, 6, 6, 9-tetramethyl-1, 4, 8-cycloundecatriene (1.05%), eudesma-4(14),11-diene (5.07%), guaia-1(10), 11-diene (4.63%), 3, 7, 11-trimethyl-1,6,10-dodecatriene-3-ol(4.01%), 1,3-dimethyl-8-(1-methylethyl)-tricyclo [4.4.0.0(2,7)] dec-3-ene (1.66%), 1, 1, 4, 7-tetramethyl-decahydro-1H-cycloprop[e] azulen-4-ol (11.00%), hexadecanoic acid methyl ester (1.53%), 4, 4, 8-trimethyltricyclo [6.3.1.0(1,5)] dodecane-2, 9-diol (2.78%), L-(+)-ascorbic acid 2,6-dihexadecanoate (20.43%), 7-octadecenoic acid methyl ester (3.81%), 3, 7, 11, 15-tetramethyl-2-hexadecen-1-ol (2.24%) and 9-octadecenoic acid (33.47%). The presence of these bioactive compounds in the leaves of Psidium guajava Linn could be the reason behind its use for the treatment of diseases and infections in herbal medicine in Nigeria.  

scholarly journals Bioassay-Guided Identification of Bioactive Compounds from Senna alata L. against Methicillin-Resistant Staphylococcus aureus

2021 ◽  
Vol 1 (3) ◽  
pp. 520-536
Author(s):  
Suwaiba Ladan Muhammad ◽  
Yusuf Wada ◽  
Mustapha Mohammed ◽  
Sani Ibrahim ◽  
Kabir Yusuf Musa ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methyl Ester ◽  
Bioactive Compounds ◽  
Diethyl Ether ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Octadecenoic Acid ◽  
Acid Methyl Ester ◽  
Methicillin Resistant ◽  
Acid Methyl ◽  
Senna Alata

Senna alata (Linn) Roxb. plant is widely used to manage various infections in folkloric medicine. Methicillin-resistant Staphylococcus aureus (MRSA) infection continues to be a major global public health problem. This study aims to investigate the bioactive components of S. alata leaves active against MRSA. The leaves of S. alata were sequentially extracted and fractionated using standard methods and screened for activities against MRSA. The diethyl ether active thin layer chromatography (TLC) spot was subjected to infrared (IR) and gas chromatography-mass spectroscopic (GC-MS) studies. The aqueous extract and diethyl ether fraction of S. alata leaves elicited the highest activity against the MRSA. The GC-MS analysis of the fraction produced 15 eluates; only the sub-fraction 13 was effective. The TLC analysis of the sub-fraction 13 revealed three spots; only the second spot produced activity. The GC-MS result of the spot showed six peaks. The spectral results for peak 3 match the data from the IR study, suggestive of 9-octadecenoic acid methyl ester. Senna alata leaves possess bioactive compounds closely related to 9-octadecenoic acid methyl ester with potent antibacterial activity against MRSA.

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