Synthesis, characterization and antibacterial activity of copper oxide nanoparticles

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Hemalatha D ◽  
Shanmugapriya B
Keyword(s):  
Antibacterial Activity ◽  
Copper Oxide ◽  
Copper Chloride ◽  
Chemical Precipitation ◽  
Copper Oxide Nanoparticles ◽  
Precipitation Method ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
X Ray ◽  
Chloride Dihydrate

Copper oxide nanoparticles were synthesized by Chemical Precipitation Method using Copper Chloride Dihydrate (CuCl2. 2H2O), Sodium hydroxide (NaOH) as a precipitating agent. The Synthesized Copper Oxide nanoparticles were characterized by X-ray diffraction (XRD), Scanning Electron Microscope (SEM), Energy Dispersive X-ray (EDX) Spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR). The Antibacterial activity of copper Oxide nanoparticles was tested against both gram positive and negative bacteria. In XRD, the crystal size and dislocation density of Copper Oxide nanoparticles were calculated, Element’s purity was determined by EDX spectra. The SEM image confirms the presence of homogeneous spherical distribution of copper oxide nanoparticles. The nanoparticles shows interactions between copper and oxygen atoms were supported by FTIR studies. Copper Oxide nanoparticles have exhibits good antibacterial activity against Klebsiella pneumonia, Escherichia coli,Staphylococcus, and Bacillus cereus.

scholarly journals Synthesis, Characterization, and Antimicrobial Activity of Copper Oxide Nanoparticles

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Maqusood Ahamed ◽  
Hisham A. Alhadlaq ◽  
M. A. Majeed Khan ◽  
Ponmurugan Karuppiah ◽  
Naif A. Al-Dhabi
Keyword(s):  
Antimicrobial Activity ◽  
Electron Microscope ◽  
Copper Oxide ◽  
Field Emission ◽  
Copper Oxide Nanoparticles ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Xrd Pattern ◽  
X Ray ◽  
Cuo Nps

We studied the structural and antimicrobial properties of copper oxide nanoparticles (CuO NPs) synthesized by a very simple precipitation technique. Copper (II) acetate was used as a precursor and sodium hydroxide as a reducing agent. X-ray diffraction patter (XRD) pattern showed the crystalline nature of CuO NPs. Field emission scanning electron microscope (FESEM) and field emission transmission electron microscope (FETEM) demonstrated the morphology of CuO NPs. The average diameter of CuO NPs calculated by TEM and XRD was around 23 nm. Energy dispersive X-ray spectroscopy (EDS) spectrum and XRD pattern suggested that prepared CuO NPs were highly pure. CuO NPs showed excellent antimicrobial activity against various bacterial strains (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumonia,Enterococcus faecalis,Shigella flexneri,Salmonella typhimurium,Proteus vulgaris,andStaphylococcus aureus). Moreover,E. coliandE. faecalisexhibited the highest sensitivity to CuO NPs whileK. pneumoniawas the least sensitive. Possible mechanisms of antimicrobial activity of CuO NPs should be further investigated.

Facile synthesis of calcium oxide nanoparticles from the carica papaya leaf extract with the significantly enhanced antibacterial activity

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Dhivya B ◽  
Sujatha K ◽  
Sudha A P
Keyword(s):  
Antibacterial Activity ◽  
Calcium Oxide ◽  
Leaf Extract ◽  
Precipitation Method ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Promising Alternative ◽  
X Ray ◽  
Sem Image ◽  
Co Precipitation

The conventional methods for the synthesis of metal oxides intake large amount of hazardous chemicals, the best promising alternative is the use of plant extracts. In this work, calcium oxide nanoparticles of 16 nm size with the cubic shape were synthesized using the papaya leaf extract by the simple greener route using calcium chloride as a source material by co-precipitation method. By using the XRD (X-Ray Diffraction), FTIR (Fourier Transform Infrared Spectroscopy), SEM (Scanning Electron Microscope) and EDAX (Energy Dispersive X-ray Analysis), the structural,surface morphology, functional group and the antibacterial activity of the synthesized calcium oxide nanoparticles were analyzed. The XRD pattern of the CaO nanoparticles was well matched with the standard value and the crystalline size obtained using the Scherer formula was 16 nm. The elemental composition of the prepared sample was confirmed by the EDAX result. The presence of the functional groups of the synthesized CaO nanoparticles was confirmed by the FTIR analysis (4000-400 cmˉ1). The cubic morphology was identified from the SEM image and the grain size ranges from 125-218 nm. The CaO nanoparticles were further evaluated for their antibacterial activity against Staphylococcus aureus and klebsiella pneumonia and from the result it was found that CaO nanoparticles was active against both gram positive and gram negativebacteria.Therefore, it may be an emerging platform for new medicines.

Synthesis and characterization of zinc doped copper oxide nanocrystals by chemical precipitation method

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Aarthe K G ◽  
Sowmiya V
Keyword(s):  
Copper Oxide ◽  
Copper Acetate ◽  
Morphological Structure ◽  
Visible Spectrum ◽  
Chemical Precipitation ◽  
Copper Oxide Nanoparticles ◽  
Chemical Precipitation Method ◽  
Precipitation Method ◽  
X Ray Diffraction ◽  
X Ray

Zinc doped copper oxide nanoparticles were synthesized by chemical precipitation method. Copper acetate is act as a precursor and sodium hydroxide will act as a reducing agent. The prepared nanoparticles were characterized by X-ray diffraction (XRD) which reveals the simple monoclinic structure. The Fourier Transform Infrared Spectroscopy confirms the functional groups present in the nano powders. The morphological Structure of the prepared crystals are analyzed by Scanning Electron Microscopy (SEM) were showed that the products consists of flaky in nature. The Bandwidth of the synthesized sample was calculated by UV- visible spectrum. The presence of compounds in nano powders were confirmed by Energy Dispersive X-ray diffraction (EDAX). Copper oxide has applications as a P-type semiconductor, because it has a narrow band gap of energy of 1.2 e V. Zinc doped copper oxide has applications in the wide variety of fields such as medicine, industries, sunscreens, agriculture etc.

scholarly journals SYNTHESIS OF COPPER OXIDE NANOPARTICLES BY CHEMICAL PRECIPITATION METHOD FOR THE DETERMINATION OF ANTIBACTERIAL EFFICACY AGAINST STREPTOCOCCUS SP. AND STAPHYLOCOCCUS SP.

2019 ◽  
pp. 135-138
Author(s):  
SHRADDHA SHIRSAT ◽  
DHANASHRI PAWAR ◽  
NISHITA JAIN ◽  
JAYANT PAWAR ◽  
VIDYA S TALE ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Quantitative Methods ◽  
Morphological Characteristics ◽  
Chemical Precipitation ◽  
Copper Oxide Nanoparticles ◽  
Chemical Precipitation Method ◽  
Precipitation Method ◽  
Oxide Nanoparticles ◽  
Antibacterial Efficacy ◽  
Cuo Nps

Objective: To determine antimicrobial efficacy of copper oxide nanoparticles (CuO NPs) against Streptococcus sp. and Staphylococcus sp. Methods: CuO NPs were synthesized using chemical precipitation method. The reducing agent, 0.1 M NaOH, was used along with 100 mM CuSO4 precursor for the synthesis of CuO NPs. The characterization of CuO NPs was done by ultraviolet-visible spectroscopy and scanning electron microscopy (SEM) to study optical and morphological characteristics, correspondingly. The identification of bacterial cultures was done through microscopic and biochemical studies. Antibacterial efficacy of CuO NPs was determined against Streptococcus sp. and Staphylococcus sp. by qualitative and quantitative methods through anti-well diffusion assay and broth dilution method, respectively. Results: The absorption spectrum and band gap were found to be at 260 nm and 4.77 eV, respectively. The SEM image of CuO NPs shows cluster of nanostructures having width of individual clusters in the range of 100 nm–500 nm. CuO NPs showed inhibition at a concentration ranging from 60 μg/mL to 1000 μg/mL. Conclusion: Finally, CuO NPs can be used as effective antibacterial agent against Streptococcus sp. and Staphylococcus sp. and may have applications in medical microbiology.

scholarly journals Preparation and Characterization of Copper Oxide Nanoparticles Synthesized via Chemical Precipitation Method

OALib ◽  
2015 ◽  
Vol 02 (03) ◽  
pp. 1-8 ◽  
Author(s):  
Ismat Zerin Luna ◽  
Lutfun Naher Hilary ◽  
A. M. Sarwaruddin Chowdhury ◽  
M. A. Gafur ◽  
Nuruzzaman Khan ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Chemical Precipitation ◽  
Copper Oxide Nanoparticles ◽  
Chemical Precipitation Method ◽  
Precipitation Method ◽  
Oxide Nanoparticles

scholarly journals Green Synthesis of Copper Oxide Nanoparticles Using Coix lacryma jobi Leaves Extract and Screening of its Potential Anticancer Activities

2021 ◽  
pp. 128-139
Author(s):  
Ksh. Sangeeta Devi ◽  
Atom Rajiv Singh ◽  
D. Velmurugan ◽  
M. Damayanti Devi ◽  
Deepak Singh Lourembam ◽  
...  
Keyword(s):  
Copper Oxide ◽  
Copper Chloride ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Visible Spectroscopy ◽  
Anticancer Activities ◽  
Chloride Dihydrate ◽  
Cuo Nps ◽  
Uv Visible

Background: Copper oxide nanoparticles(CuO NPs) have been powerful evidence in several in vitro studies such as cytotoxicity and antimicrobial compared with other metal oxide. Here, we have synthesized green CuO NPs using Coix lacryma jobi leaves extracts. Place and Duration of Study: Department of Chemistry  Manipur University, Manipur, India and Regional Institute of Medical Sciences, Imphal, India between February 2019 to March 2021. Methodology: Green CuO NPs nanoparticles were synthesized from Copper chloride dihydrate (CuCl2.2H2O) using Coix lacryma jobi leaves extract, and the synthesized green CuO NPs were characterized using Field Emission Scanning Electron Microscopy (FESEM) - Energy Dispersive Spectroscopy, IR Spectroscopy, UV-Visible Spectroscopy, Powder X-Ray diffraction Spectroscopy and HR-TEM where FESEM-EDS determined the purity of CuO NPs. Results: No other impurities present were observed in EDS, and the PXRD spectra show the crystallite size of CuO NPs with respect to the (002) plane is found to be 25.2 nm, and the presence of CuO NPs at adsorption spectrum with a distinct peak at 282 nm was determined by  UV-Visible spectroscopy and the homogenous morphology and crystalline nature of the CuO NPs were determined from TEM micrograph and SAED pattern. In applications, the substantial anticancer activity of green CuO NPs (synthesized using Coix lacryma jobi leaves extract) was proved on human cervical and lung cancer cell lines with IC50 values of 31.88 μg/ml and 15.61 μg/ml, respectively.

ANTIBIOTIC PROFILE AND ANTIBACTERIAL ACTIVITY OF COPPER OXIDE NANOPARTICLES AGAINST Pseudomonas fluorescens ISOLATED FROM WOUND INFECTION

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Haider Qassim Raheem ◽  
Takwa S. Al-meamar ◽  
Anas M. Almamoori
Keyword(s):  
Antibacterial Activity ◽  
Copper Oxide ◽  
Pseudomonas Fluorescens ◽  
Wide Spectrum ◽  
Copper Oxide Nanoparticles ◽  
Morphological Properties ◽  
Clinical Samples ◽  
Oxide Nanoparticles ◽  
Cuo Nps ◽  
Disk Diffusion Assay

Fifty specimens were collected from wound patients who visited Al-Hilla Teaching Hospital. The samples were grown on Blood and MacConkey agar for 24-48 hr at 37oC. The bacterial isolates which achieved as a pure and predominant growth from clinical samples as Pseudomonas fluorescens, were identified using morphological properties and Vitek2 system. The anti-bacterial activity of copper oxide nanoparticles (CuO NPs) against was tested by (disk diffusion assay) using dilutions of (400, 200, 100, 50, 25, and 12.5‎µ‎g/ml). The (MIC and MBC) of each isolate was determined. CuO NPs shows wide spectrum antibacterial activity against tested bacteria with rise zone of inhibition diameter that is proportionate with the increase in nanoparticle concentration. The MIC of CuO NPs extended from 100-200‎µ‎g/ml and the MBC ranged from 200-400‎µ‎g/ml. The antibiotic profile was determined by Viteck 2 compact system (Biomérieux). CuO NPs‎ found highly effective and safe in P. fluorescens wounds infections comparing with used antibiotics.

Green synthesis of copper oxide nanoparticles using aloe vera extract

2020 ◽  
Vol 3 (3) ◽  
Author(s):  
Hemalatha D ◽  
Saraswath S
Keyword(s):  
Copper Oxide ◽  
Biomedical Application ◽  
Aloe Vera ◽  
Copper Oxide Nanoparticles ◽  
Klebsiella Pneumonia ◽  
Oxide Nanoparticles ◽  
Cupric Sulfate ◽  
X Ray Diffraction ◽  
Fouriertransform Infrared Spectroscopy ◽  
Effective Use

In material science, green method for synthesis of nanomaterials is feasible, cheaper and eco-friendly protocol. To accomplish this phenomenon, present study was aimed to synthesize Copper oxide nanoparticles using leaf extract of Aloevera with two different precursors CuCl2.2H2O (Cupric chloride) and CuSo4.5H2O (Cupric sulfate). The extraction of Aloevera is employed as reducing and stabilizing agent for this synthesis.Copper oxide Nanoparticles is effective use of biomedical application due to their antibacterial function. The synthesized Copper oxide nanoparticles were characterized by X-Ray Diffraction Spectroscopy (XRD), Energy Dispersive Spectroscopy (EDX), FourierTransform Infrared Spectroscopy (FT- IR) and Scanning Electron Microscope(SEM). XRD studies reveal the crystallographic nature of Copper oxide nanoparticles. Furthermore the Copper oxide nanoparticles have good Antibacterial activity against both gram negative (E.Coli, Klebsiella pneumonia) and gram positive (Bacillus cereus, Staphylococcus aureus)bacteria.

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