scholarly journals The Impact of Gender and Body Mass Index on Lipid Profile of Diabetic Patients Treated in Royal Medical Services

Author(s):  
Hussein H Dmour
2021 ◽  
Vol 26 ◽  
pp. 2515690X2110110
Author(s):  
Wiraphol Phimarn ◽  
Bunleu Sungthong ◽  
Hiroyuki Itabe

Aim. The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed. Methods. Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors. Results. Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment. Conclusions. This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.


2017 ◽  
Vol 5 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Soha M. Abd El Dayem ◽  
Mona Abd El Kader ◽  
Soheir Ibrahim ◽  
Enas Mokhtar ◽  
Eman Abd El Megeed

AIM: To evaluate leptin and lipid profile in overweight patients with type 1 diabetes.PATIENTS AND METHODS: The study included 50 overweight patients with type 1 diabetes and 50 age and sex matched healthy controls. Blood samples were taken for evaluation of glycosylated haemoglobin, lipid profile and leptin. Also, urine samples were taken for evaluation of albumin/creatinine ratio.RESULTS: Leptin level was significantly lower in overweight with type 1 diabetes and showed a significant positive correlation with hip circumference and body mass index and negative correlation with glycosylated haemoglobin (HbA1c). Leptin level was significantly lower in overweight diabetic patients with HbA1c > 7.5 %. The best cut-off point between overweight diabetic group and control group regarding leptin levels was found at 16.9 (ng/ml) with a sensitivity of 68% and specificity of 56%, area under the curve 0.623.CONCLUSION: Leptin levels were found to be low in overweight patients with type 1 diabetes and showed correlation with the body mass index and hip circumference. LDL was significantly higher while HDL was significantly lower in the diabetic, overweight group indicating increased risk of cardiovascular disease. Leptin level in overweight diabetic patients might be related to the metabolic control.


2020 ◽  
Vol 41 (8) ◽  
pp. 945-953
Author(s):  
Gin Way Law ◽  
Kae Sian Tay ◽  
Akshay Padki ◽  
Khai Cheong Wong ◽  
Karen Ting Zhang ◽  
...  

Background: Literature is sparse on whether diabetes affects outcomes of hallux valgus surgery. With the rising global prevalence of diabetes and diabetes being an independent predictor of poorer outcomes, particularly in foot and ankle surgery, we aimed to investigate the impact of diabetes on the outcomes of hallux valgus surgery. Methods: We conducted a retrospective comparative cohort study of prospectively collected registry data of 951 feet in 721 patients who underwent surgery for symptomatic hallux valgus between 2007 and 2015 at our institution. All patients with diabetes were identified and matched with patients without diabetes for age, sex, and body mass index in a 1:2 ratio to construct the matched cohorts for analysis. Glycemic control in the diabetic cohort was assessed using preoperative HbA1c. The primary outcome measure was complication rates. Secondary outcomes were (1) deformity correction using the hallux valgus and intermetatarsal angles; (2) patient-reported outcomes using visual analog scale (VAS) for pain, Short Form–36 (SF-36) Physical and Mental Health subscales, and American Orthopaedic Foot & Ankle Society (AOFAS) scores; (3) patient satisfaction; and (4) reoperation rates up to 2 years postoperatively. Forty diabetic patients were identified and matched to 80 nondiabetic patients. Although matching was only performed for age, sex, and body mass index, the diabetic and the nondiabetic cohorts were also similar in hallux valgus severity, preoperative scores, and types of procedures performed. Results: The mean preoperative HbA1c in our diabetic cohort was 7.1%. Both the diabetic and nondiabetic cohorts showed excellent AOFAS and VAS scores with no differences in degree of deformity correction, complication profiles, reoperation rates, outcome scores, and satisfaction at both 6 months and 2 years postoperatively. Conclusion: We believe stringent patient selection was key to reduced complication rates and good outcomes in diabetic patients. Well-selected diabetic patients remain suitable candidates for hallux valgus surgery. Level of Evidence: Level III, retrospective comparative study.


Author(s):  
Amiya Bhonsle ◽  
Shweta Parwe ◽  
Milind Nisargandha

Background: Sthoulya described as Obesity occurs due to the vitiation of Kapha & Vata. The signs and symptoms of Sthoulya can be correlated with Obesity. This has been said in Ayurveda and Sthaulya purusha (Obese person) is considered one of the nindita Purusha. Lekhaniya gana contains the drugs like Triphala, Shatpushpa, Madhu (Honey), Ushaka, Kasis, Tuttha, Shilajit, Saindhava (Salt), Yavakshar, Gomutra (Cow Urine) which are having specially lekhaniya (Scraping) properties, Kapha and Meda (fat) hara property, in sthaulya increased kapha and meda (fat) is seen, the medicine having these lekhaniya property helps to scrap the excess fat from the body so this medicine is helpful to reduce fat. While Modified Vachadi Gana (Group of herbs) contains Devdaru (Cedrus Deodara), Shunthi (Zingiber Officinale), Vacha (Acorus Calamus), Haritaki (Terminalia Chebula), Ativisha (Aconitum Heterophyllum), Nagarmotha (Cyperus Rotundus), Ushaka, Kasis (Ferrous Sulfate), Tuttha (Blue Vitriol), Shilajit (Asphaltum), Saindhava (salt), Yavakshar (Hordeum Vulgare), Modified Vachadi gana having  vata and kapha hara property & Lekhaniya (Scraping)  property both.   So it is used in vata kaphaja vikara like sthaulya so to treat it vata kapha reducing medicine is to use. Modified Vachadi Gana having those above properties apart from that also having lekhaniya property. Hence, it also helps to scrap the excess fat from the body, so this medicine is helpful to reduce fat. Aim: To study the effect of Lekhana Basti & Modified Vachadi Gana Basti along with Navak Guguulu  in sthoulya (Obesity). Objectives: To study the impact of Lekhana Basti on body mass index, body circumference measurements, skinfold thickness, lipid profile, To study the impact of Vachadi gana yoga basti (Modified) on body mass index, body circumference measurements, skinfold thickness & lipid profile, To compare the efficacy of Lekhana Basti and Modified Vachadi Gana basti on body mass Index, body circumference measurements, skinfold thickness & lipid profile. Materials and Methods: A total of 35 patients will be selected in each group from the outpatient department of Panchakarma MGACH & RC. Basti will be done in Yog basti pattern. In Group A, Lekhana Basti & In Group B, Modified Vachadi Basti will be used. After Basti Krama 16 Days, Parihara Kala is to be given. Conclusion: Based on the result conclusion will be drawn.


2017 ◽  
Vol 4 (2) ◽  
pp. 1021-1026
Author(s):  
Reem Ibrahim Mahadeen ◽  
◽  
Maysoon Hwaidi ◽  
ManalEdiab Al-Harasis ◽  
Ayman Ragheb Jaarah ◽  
...  

2018 ◽  
Vol 14 (4) ◽  
pp. 184-188
Author(s):  
Prerna Bansal ◽  
Hari Prasad Upadhyay

Background: Diabetes is an important public health problem as global prevalence of diabetes has nearly doubled reflecting an increase in risk factors like overweight or obesity and dyslipidemia. Both obesity and dyslipidemia share a common pathogenesis associated with “insulin resistance”. Thus the aim of this study is to find out correlation between BMI and lipid profile in type 2 diabetics. Materials and Methods: A cross-sectional study was conducted among 136 type 2 diabetes patients visiting the Diabetes Clinic of College of Medical Sciences, Bharatpur, Nepal during Jan-Dec 2017 and who went through lipid profile testing. The informations were taken from hospital records. To find the significant association between categorical variables chi-square test was used. P-value less than 0.05 were considered as statistically significant. To find the association between continuous variables correlation was used. Results: Out of 136 diabetic patients 77.2% of patients were either overweight or obese. 92.6% of patients had dyslipidemia. Among which 58.1% had high TG levels, 56.6% had high LDL levels, 34.6% had high TC levels and 44.9% had low HDL levels. The overall mean ± SD of age was 54.54±12.03 years and of BMI was 28.54±4.57. Positive correlation was seen between BMI with LDL levels and negative correlation with HDL levels. The correlation with other lipid profile parameters were negative. These correlations were found to be statistically not significant. But statistically significant association was seen between gender with weight, total cholesterol and HDL levels. Conclusions: Obesity and dyslipidemia were highly prevalent. As BMI increases LDL levels increases and HDL levels decreases. Also increased weight and abnormal lipid levels of total cholesterol and HDL were found significantly higher among females than males. Keywords: body mass index; lipid profile; type 2 diabetes; HDL; LDL.


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