scholarly journals United States smallpox response plans: a commentary from the Bioterrorism Taskforce (BICHAT) perspective

2002 ◽  
Vol 6 (43) ◽  
Author(s):  
J Hendriks ◽  
A Tegnell ◽  
P Bossi ◽  
A Baka ◽  
F van Loock ◽  
...  
Keyword(s):  
United States ◽  
Large Population ◽  
The United States ◽  
Crucial Issue ◽  
Defense Department ◽  
Preparedness Plan ◽  
The Us ◽  
Control And Prevention ◽  
Deliberate Release ◽  
Response Plan

The US plan As the United States (US) continues to expand counterterrorism capabilities, smallpox has emerged as perhaps the most feared biological weapon because it is so contagious and deadly. With the possibility of a war with Iraq, the US Defense Department has asked for enough vaccine from the national smallpox vaccine stockpile for 1 million military personnel, to be available by the beginning of November 2002. To protect US citizens against a deliberate release of the smallpox virus, US federal experts have been working on a comprehensive preparedness plan with two tracks: a (pre-event) vaccination programme for the emergency medical workers most likely to see an initial case of smallpox, and a (post- event) mass vaccination plan if an attack occurs. The latter is now available and has recently been distributed to all states by the Centers for Disease Control and Prevention (CDC) (http://www.bt.cdc.gov/agent/smallpox/response-plan/index.asp). The documentation provided includes many detailed instructions and recommendations on the logistics that go with such a massive campaign. Of particular interest are the forms included for obtaining consent from people about to be vaccinated - a crucial issue. The manual states that following a confirmed smallpox outbreak in the US, rapid voluntary vaccination of a large population may be required.

scholarly journals CDC releases interim smallpox response plan and guidelines

2001 ◽  
Vol 5 (51) ◽  
Author(s):  
R Harling
Keyword(s):  
United States ◽  
Disease Control ◽  
The United States ◽  
Mass Vaccination ◽  
Ring Vaccination ◽  
Control And Prevention ◽  
Deliberate Release ◽  
Response Plan ◽  
Centers For Disease Control ◽  
Spread Of Infection

The Centers for Disease Control and Prevention (CDC) in the United States (US) last week released its plans to cope with a deliberate release of smallpox (1). The plan centres on rapid ring vaccination of the contacts of infected individuals to contain the spread of infection. Mass vaccination in advance of an outbreak will not be used, partly because the risks associated with vaccination outweigh the risks of exposure to smallpox.

scholarly journals The Check and Report Ebola (CARE+) Program to Monitor Travelers for Ebola After Arrival to the United States, 2014-2016

2019 ◽  
Vol 134 (6) ◽  
pp. 592-598 ◽  
Author(s):  
Heather A. Joseph ◽  
Abbey E. Wojno ◽  
Kelly Winter ◽  
Onalee Grady-Erickson ◽  
Erin Hawes ◽  
...  
Keyword(s):  
Public Health ◽  
United States ◽  
West Africa ◽  
Emerging Infectious Diseases ◽  
Care Program ◽  
The United States ◽  
The Us ◽  
Us Government ◽  
Public Health Authorities ◽  
Control And Prevention

The 2014-2016 Ebola epidemic in West Africa influenced how public health officials considered migration and emerging infectious diseases. Responding to the public’s concerns, the US government introduced enhanced entry screening and post-arrival monitoring by public health authorities to reduce the risk of importation and domestic transmission of Ebola while continuing to allow travel from West Africa. This case study describes a new initiative, the Check and Report Ebola (CARE+) program that engaged travelers arriving to the United States from countries with Ebola outbreaks. The Centers for Disease Control and Prevention employed CARE ambassadors, who quickly communicated with incoming travelers and gave them practical resources to boost their participation in monitoring for Ebola. The program aimed to increase travelers’ knowledge of Ebola symptoms and how to seek medical care safely, increase travelers’ awareness of monitoring requirements, reduce barriers to monitoring, and increase trust in the US public health system. This program could be adapted for use in future outbreaks that involve the potential importation of disease and require the education and active engagement of travelers to participate in post-arrival monitoring.

scholarly journals Understanding Implementation Challenges to Genetic Testing for Familial Hypercholesterolemia in the United States

2019 ◽  
Vol 9 (1) ◽  
pp. 9 ◽  
Author(s):  
Rachele Hendricks-Sturrup ◽  
Christine Lu
Keyword(s):  
United States ◽  
Genetic Testing ◽  
Familial Hypercholesterolemia ◽  
Ethnic Diversity ◽  
Heart Association ◽  
The United States ◽  
Cvd Risk ◽  
Implementation Challenges ◽  
The Us ◽  
Control And Prevention

Cardiovascular disease (CVD) is the leading cause of death in the United States (US), with familial hypercholesterolemia (FH) being a major inherited and genetic risk factor for premature CVD and atherosclerosis. Genetic testing has helped patients and providers confirm the presence of known pathogenic and likely pathogenic variations in FH-associated genes. Key organizations, such as the Centers for Disease Control and Prevention (CDC), American Heart Association (AHA), FH Foundation, and National Lipid Association (NLA), have recognized the clinical utility of FH genetic testing. However, FH genetic testing is underutilized in clinical practice in the US for reasons that are underexplored through the lens of implementation science. In this commentary, we discuss seven key implementation challenges that must be overcome to strengthen the clinical adoption of FH genetic testing in the US. These implementation challenges center on evidence of cost-effectiveness, navigating patient and provider preferences and concerns, gender and ethnic diversity and representation in genetic testing, and establishing clinical consensus around FH genetic testing based on the latest and most relevant research findings. Overcoming these implementation challenges is imperative to the mission of reducing CVD risk in the US.

Mortality in the US by education level

2020 ◽  
Vol 14 (2) ◽  
pp. 384-419
Author(s):  
Cristian Redondo Lourés ◽  
Andrew J. G. Cairns
Keyword(s):  
United States ◽  
Disease Control ◽  
Cause Of Death ◽  
The United States ◽  
Mortality Rates ◽  
Education Level ◽  
The Us ◽  
Control And Prevention ◽  
Centers For Disease Control ◽  
Death Data

AbstractDifferent mortality rates for different socio-economic groups within a population have been consistently reported throughout the years. In this study, we aim to exploit data from multiple public sources, including highly detailed cause-of-death data from the United States Centers for Disease Control and Prevention, to explore the mortality gap between the better and worse off in the US during the period 1989–2015, using education as a proxy.

scholarly journals Estimates of presumed population immunity to SARS-CoV-2 by state in the United States, August 2021

2021 ◽  
Author(s):  
Marie C.D. Stoner ◽  
Frederick J. Angulo ◽  
Sarah Rhea ◽  
Linda Morris Brown ◽  
Jessica E. Atwell ◽  
...  
Keyword(s):  
United States ◽  
Natural Infection ◽  
Population Level ◽  
The United States ◽  
Viral Transmission ◽  
Population Immunity ◽  
Seroprevalence Data ◽  
The Us ◽  
Control And Prevention ◽  
Waning Immunity

ABSTRACTBackgroundInformation is needed to monitor progress toward a level of population immunity to SARS-CoV-2 sufficient to disrupt viral transmission. We estimated the percentage of the United States (US) population with presumed immunity to SARS-CoV-2 due to vaccination, natural infection, or both as of August 26, 2021.MethodsPublicly available data as of August 26, 2021, from the Centers for Disease Control and Prevention (CDC) were used to calculate presumed population immunity by state. Seroprevalence data were used to estimate the percentage of the population previously infected with SARS-CoV-2, with adjustments for underreporting. Vaccination coverage data for both fully and partially vaccinated persons were used to calculate presumed immunity from vaccination. Finally, we estimated the percentage of the total population in each state with presumed immunity to SARS-CoV-2, with a sensitivity analysis to account for waning immunity, and compared these estimates to a range of population immunity thresholds.ResultsPresumed population immunity varied among states (43.1% to 70.6%), with 19 states with 60% or less of their population having been infected or vaccinated. Four states have presumed immunity greater than thresholds estimated to be sufficient to disrupt transmission of less infectious variants (67%), and none were greater than the threshold estimated for more infectious variants (78% or higher).ConclusionsThe US remains a distance below the threshold sufficient to disrupt viral transmission, with some states remarkably low. As more infectious variants emerge, it is critical that vaccination efforts intensify across all states and ages for which the vaccines are approved.SummaryAs of August 26, 2021, no state has reached a population level of immunity thought to be sufficient to disrupt transmission. (78% or higher), with some states having remarkably low presumed immunity.

Child abuse in the United States

2014 ◽  
Author(s):  
Margaret Spinelli
Keyword(s):  
United States ◽  
Child Abuse ◽  
Disease Control ◽  
Child Abuse And Neglect ◽  
The United States ◽  
Alternative Response ◽  
The Us ◽  
Abuse And Neglect ◽  
Control And Prevention ◽  
Centers For Disease Control

Child abuse is a major cause of morbidity and mortality in the United States and other countries. It is the second leading cause of death among children in the US. All 50 States, the District of Columbia, and the US Territories have mandatory child abuse and neglect reporting laws that require certain professionals and institutions to report suspected maltreatment to a child protective services (CPS) agency. Four major types of maltreatment are considered: neglect, physical abuse, psychological maltreatment, and sexual abuse (Centers for Disease Control and Prevention 2010). Once an allegation or referral of child abuse is received by a CPS agency, the majority of reports receive investigations to establish whether or not an intervention is needed. Some reports receive an alternative response in which safety and risk assessments are conducted, but the focus is on working with the family to address issues. Investigations involve gathering evidence to substantiate the alleged maltreatment. Data from reports on child abuse is derived from the National Child Abuse and Neglect Data System (NCANDS), which aggregates and publishes statistics from state child protection agencies. The first report from NCANDS was based on data for 1990. Case-level data include information about the characteristics of reports of abuse and neglect that are made to CPS agencies, the children involved, the types of maltreatment that are alleged, the dispositions of the CPS responses, the risk factors of the child and the caregivers, the services that are provided, and the perpetrators (Centers for Disease Control and Prevention 2010). During 2010, the NCANSDS reported that an estimated 3.3 million referrals estimated to include 5.9 million children were received by CPS agencies. Of the nearly 2 million reports that were screened and received a CPS response, 90.3% received an investigation response and 9.7% received an alternative response (Centers for Disease Control and Prevention 2010). Of the 1,793,724 reports that received an investigation in 2010, 436,321 were substantiated; 24,976 were found to be indicated (likely but unsubstantiated); and 1,262,118 were found to be unsubstantiated. Three-fifths of reports of alleged child abuse and neglect were made by professionals.

scholarly journals Reverse Migration to Mexico Led to US Undocumented Population Decline: 2010 to 2018

2020 ◽  
Vol 8 (1) ◽  
pp. 32-41 ◽  
Author(s):  
Robert Warren
Keyword(s):  
United States ◽  
New York ◽  
Large Population ◽  
Population Decline ◽  
New York State ◽  
The United States ◽  
Executive Summary ◽  
Reverse Migration ◽  
The Us ◽  
Almost All

Executive Summary This report presents estimates of the undocumented population residing in the United States in 2018, highlighting demographic changes since 2010. The Center for Migration Studies of New York (CMS) compiled these estimates based primarily on information collected in the US Census Bureau’s American Community Survey (ACS). The annual CMS estimates of undocumented residents for 2010 to 2018 include all the detailed characteristics collected in the ACS. 1 A summary of the CMS estimation procedures, as well as a discussion of the plausibility of the estimates, is provided in the Appendix . The total undocumented population in the United States continued to decline in 2018, primarily because large numbers of undocumented residents returned to Mexico. From 2010 to 2018, a total of 2.6 million Mexican nationals left the US undocumented population; 2 about 1.1 million, or 45 percent of them, returned to Mexico voluntarily. The decline in the US undocumented population from Mexico since 2010 contributed to declines in the undocumented population in many states. Major findings include the following: The total US undocumented population was 10.6 million in 2018, a decline of about 80,000 from 2017, and a drop of 1.2 million, or 10 percent, since 2010. Since 2010, about two-thirds of new arrivals have overstayed temporary visas and one-third entered illegally across the border. The undocumented population from Mexico fell from 6.6 million in 2010 to 5.1 million in 2018, a decline of 1.5 million, or 23 percent. Total arrivals in the US undocumented population from El Salvador, Guatemala, and Honduras — despite high numbers of Border Patrol apprehensions of these populations in recent years — remained at about the same level in 2018 as in the previous four years. 3 The total undocumented population in California was 2.3 million in 2018, a decline of about 600,000 compared to 2.9 million in 2010. The number from Mexico residing in the state dropped by 605,000 from 2010 to 2018. The undocumented population in New York State fell by 230,000, or 25 percent, from 2010 to 2018. Declines were largest for Jamaica (−51 percent), Trinidad and Tobago (−50 percent), Ecuador (−44 percent), and Mexico (−34 percent). The results shown here reinforce the view that improving social and economic conditions in sending countries would not only reduce pressure at the border but also likely cause a large decline in the undocumented population. Two countries had especially large population changes — in different directions — in the 2010 to 2018 period. The population from Poland dropped steadily, from 93,000 to 39,000, while the population from Venezuela increased from 65,000 to 172,000. Almost all the increase from Venezuela occurred after 2014.

Preparing for SARS-CoV-2 Vaccines in US Immigrant Communities: Strategies for Allocation, Distribution, and Communication

2020 ◽  
pp. e1-e5
Author(s):  
Eva H. Clark ◽  
Karla Fredricks ◽  
Laila Woc-Colburn ◽  
Maria Elena Bottazzi ◽  
Jill Weatherhead
Keyword(s):  
Public Health ◽  
United States ◽  
Department Of Defense ◽  
Population Level ◽  
The United States ◽  
Immigrant Communities ◽  
Private Partnership ◽  
The Us ◽  
Us Government ◽  
Control And Prevention

Widely administered efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are the safest and most efficient way to achieve individual- and population-level immunity, making SARS-CoV-2 vaccination the most viable strategy for controlling the coronavirus disease 2019 (COVID-19) pandemic in the United States. To this end, the US government has invested more than $10 billion in “Operation Warp Speed,” a public-private partnership including the Centers for Disease Control and Prevention (CDC), the US Food and Drug Administration (FDA), and the US Department of Defense. Operation Warp Speed funded the development of several SARS-CoV-2 vaccines and aimed to deliver 300 million doses of a vaccine by the ambitious date of January 2021. (Am J Public Health. Published online ahead of print December 22, 2020: e1–e5. https://doi.org/10.2105/AJPH.2020.306047 )

scholarly journals The Epidemic Intelligence Service in the United States

2001 ◽  
Vol 6 (3) ◽  
pp. 34-36
Author(s):  
Stephen M. Ostroff
Keyword(s):  
United States ◽  
50Th Anniversary ◽  
Training Programme ◽  
The United States ◽  
Wide Range ◽  
Epidemic Intelligence ◽  
The Us ◽  
The Korean War ◽  
Control And Prevention ◽  
Intelligence Service

The Epidemic Intelligence Service (EIS) - the two year applied epidemiology training programme of the United States (US) Centers for Disease Control and Prevention (CDC) - celebrates its 50th anniversary in 2001. Developed during the Korean war, only five years after CDC was established, the stimulus behind developing the EIS was a lack of trained field investigators should biological agents be intentionally used against the US population. It was, however, clear to Alexander Langmuir, the head of epidemiology at CDC and founder of the EIS, that his trainees would engage in a wide range of activities and help fill gaps in the US for epidemiologists with the skills and practical field experience to investigate and control naturally occurring outbreaks of diseases.

scholarly journals Vitamin C supplementation for the treatment of osteoarthritis: perspectives on the past, present, and future

2021 ◽  
Vol 12 ◽  
pp. 204062232110470
Author(s):  
Burton Dunlap ◽  
G. Taylor Patterson ◽  
Sandeep Kumar ◽  
Sagar Vyavahare ◽  
Samarth Mishra ◽  
...  
Keyword(s):  
United States ◽  
Vitamin C ◽  
The United States ◽  
Health Crisis ◽  
The Past ◽  
The Us ◽  
Control And Prevention ◽  
Vitamin C Supplementation ◽  
Prevalence Of Obesity ◽  
Ros Formation

According to the US Centers for Disease Control and Prevention (CDC), an estimated 14% of adults in the United States have either been diagnosed with osteoarthritis (OA) or have symptoms suggestive of the disease. The CDC also points out that the incidence of OA has been gradually increasing over the past 30 years. What is more worrisome is that this trend is going to accelerate due to the aging demographics of the United States and the increasing prevalence of obesity seen in the country. The need for better preventive treatments and efficacious therapeutics are direly needed to combat this public health crisis. Among the possible treatments being hypothesized, antioxidant supplementation has become one of the most widely studied over the past decade due to its ability to attenuate reactive oxygen species (ROS) formation within chondrocytes, a critical step in the pathogenesis of this disease. Vitamin C has emerged as among the most promising of the antioxidant group, with many animal and human studies having been conducted in recent years. Although many of the studies have shown encouraging results in terms of preventing OA, others have reached opposite conclusions, thus making the data controversial. However, after reviewing several of these studies, we hypothesize that certain parameters may not have been properly considered during data collection. In the end, more randomized placebo-controlled trials in humans are desperately needed in order to fully understand whether vitamin C therapy is efficacious in treating and/or preventing OA.

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