scholarly journals ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES AGAINST NEISSERIA GONORRHOEAE AND CANDIDA ALBICANS

2020 ◽  
Vol 8 (6) ◽  
pp. 179-187
Author(s):  
Titik Taufikurohmah ◽  
Tasha Anandya Tantyani
Keyword(s):  
Antibacterial Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Neisseria Gonorrhoeae ◽  
Diffusion Method ◽  
Antibacterial And Antifungal Activity ◽  
Disk Diffusion Method ◽  
Fungal Inhibition ◽  
Inhibition Response ◽  
Antibacterial And Antifungal

This Research on the antibacterial and antifungal activity of nanosilver against Neisseria gonorrhoeae and Candida albincas fungi has been carried out. The purpose of this study was to determine antibacterial activity of nanosilver against Neisseria gonorrhoeae and antifungal activity against Candida albincas. Synthesis Nanosilver uses bottom up method and characterized using UV-Vis Spectrophotometer. Nanosliver concentrations used were 30, 40, 50, and 60 ppm. Antibacterial and antifungal activity tests using disk diffusion method. Observations obtained in form of the presence or absence of clear zones formed around paper discs indicate the inhibition of nanosilver on microbial growth. The results of testing the antifungal activity of Candida albicans on nanosilver with concentrations of 30, 40, 50 and 60 ppm resulted in clear zones of 9.73 nm, 11.46 nm, 11.93 nm, and 13 nm with fungal inhibition response categories is medium and strong. The results antibacterial activity test of Neisseria gonorrhoeae on nanosilver with concentrations of 30, 40, 50 and 60 ppm did not show any clear zone around the disc, it showed that nanosilver in this study did not have antibacterial activity against Neisseria gonorrhoeae.

scholarly journals Evaluation of Antibacterial and Antifungal Activity of Herbs Used in Treatment of Diabetes, Malaria and Pneumonia in Kisii and Nyamira Counties Region, Kenya

2021 ◽  
Vol 5 (4) ◽  
pp. 330-337
Author(s):  
Moses A. Guto Maobe ◽  
Leonard Gitu ◽  
Erastus Gatebe
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Diffusion Method ◽  
Root Extract ◽  
Plant Parts ◽  
Toddalia Asiatica ◽  
Antibacterial And Antifungal

The herbs Carissa spinarum, Physalis minima and Toddalia asiatica have traditionally been used in healing diabetes, malaria and pneumonia by the communities around the Kisii region, Kenya. However in the available literature, there is scanty information on effectiveness of different plant parts of the herbs in healing the ailments. The objective of this study was to investigate the potential antimicrobial and antifungal activity of methanolic extract of whole plant Physalis minima, leaf and root of Carissa spinarum and Toddalia asiatica against gram positive bacteria Staphylococcus aureus (ATCC 25923), gram negative bacteria Escherichia coli (ATCC 25922) and fungus Candida albicans (ATCC14053). Antibiotic disc methicillin, cotrimoxazole, chloramphenicol, gentamicin, ampicillin, nalidixic and nitrofurantoin were used in the study. In each herb, plant part was extracted by soaking in methanol/dichloromethane in ratio 1:1 for a week, filtered, concentrated by rotary vapor and cooled. The same process was repeated three times for all samples. The study was conducted by agar well diffusion method. Methanolic root extract of Toddalia asiatica showed highest antibacterial activity against Staphylococcus aureus (ATCC 25923), root extract of Carissa spinarum had highest antibacterial activity against Escherichia coli (ATCC 25922) while root extract of Toddalia asiatica showed highest antifungal activity. It was concluded that root extract of Toddalia asiatica showed highest antibacterial activity 16.7mm  against Staphylococcus aureus(ATCC 25923), root extract of Carissa spinarum had highest antibacterial activity 10 mm  against Escherichia coli (ATCC 25922)  while  root extract of Toddalia asiatica had highest antifungal activity 18 mm against Candida albicans.

scholarly journals Comparison of Antimicrobial Activity ofAllium sativumCloves from China and Taşköprü, Turkey

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Ali Yetgin ◽  
Kerem Canlı ◽  
Ergin Murat Altuner
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Allium Sativum ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Disk Diffusion Method ◽  
Gram Negative ◽  
Gram Positive Bacteria

In this study, antimicrobial activities of two different samples ofAllium sativumL. from Turkey (TR) (Taşköprü, Kastamonu, Turkey) and China (CN) were determined. A broad spectrum of Gram-negative and Gram-positive bacteria (17 bacteria) including species ofBacillus,Enterobacter,Enterococcus,Escherichia,Klebsiella,Listeria,Pseudomonas,Salmonella, andStaphylococcuswere used for testing antibacterial activity. In addition, antifungal activity againstCandida albicanswas also investigated. Antimicrobial activity was tested by using 3 different processes (chopping, freezing, and slicing by the disk diffusion method). The results showed that TR garlic presented more antimicrobial activity than CN garlic. Mechanism of activity of CN garlic could be proposed to be different from that of TR garlic.

scholarly journals ANTIMICROBIAL STUDIES OF DIFFERENT EXTRACTS OF HOLOPTELEA INTEGRIFOLIA (ROXB.) LEAVES

2020 ◽  
pp. 191-193
Author(s):  
REKHA TRIPATHI
Keyword(s):  
Aqueous Extract ◽  
Methanolic Extract ◽  
Diffusion Method ◽  
Antibacterial And Antifungal Activity ◽  
Disk Diffusion Method ◽  
Rhizoctonia Bataticola ◽  
Antimicrobial Studies ◽  
Almost All ◽  
Antibacterial And Antifungal ◽  
Antifungal Efficacy

Objective: The aim of this study was to examine various extracts of leaves of Holoptelea integrifolia against some test bacteria and test fungi. Methods: Disk diffusion method was adopted for the assessment of antimicrobial activity. Amikacin and nystatin were used as standard drugs for antibacterial and antifungal activity, respectively. Results: The screening data indicated that all four extracts showed antibacterial activity against Staphylococcus aureus, but the growth of this bacteria was inhibited the most by the aqueous extract. In the case of antifungal efficacy, all the extracts inhibited the growth of almost all the test fungi. Petroleum ether and benzene extracts showed maximum efficacy against Aspergillus flavus, whereas methanolic extract and aqueous extract inhibited the growth of Rhizoctonia bataticola significantly. Conclusion: Different extracts of leaves of H. integrifolia were significantly active against selected test fungi and they can be a harmless alternative of expensive conventional medicines.

scholarly journals Synthesis, Spectral Characterization, and Antibacterial and Antifungal Studies of PANI/V2O5Nanocomposites

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Chakradhar Sridhar ◽  
Nagesh Gunvanthrao Yernale ◽  
M. V. N. Ambika Prasad
Keyword(s):  
Antifungal Activity ◽  
Sol Gel ◽  
Chemical Oxidation ◽  
Diffusion Method ◽  
Antibacterial And Antifungal Activity ◽  
X Ray Diffraction ◽  
Xrd Techniques ◽  
Antibacterial And Antifungal

The present study deals with the synthesis and characterization of nanocrystalline vanadium pentoxide (V2O5) nanoparticles and their antibacterial and antifungal activity onStaphylococcus aureus and Aspergillus niger, respectively, by agar diffusion method. The metal oxide has been synthesized by employing the sol-gel method, polyaniline (PANI) has been synthesized by chemical oxidation, and PANI/V2O5composites have been synthesized byin situpolymerization method with different ratios (10, 20, 30, 40, and 50 weight%) of V2O5in PANI. The newly prepared composites were characterized by FTIR and powder X-ray diffraction (P-XRD) techniques and are found to be formed of PANI/V2O5nanocomposites, and also the compounds showed moderate antibacterial and antifungal activity.

scholarly journals Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands

2002 ◽  
Vol 8 (5) ◽  
pp. 269-274 ◽  
Author(s):  
V. Zelenák ◽  
K. Györyová ◽  
D. Mlynarcík
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Biological Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Organic Ligands ◽  
Antibacterial And Antifungal Activity ◽  
Bacterial Strains ◽  
Structural Types ◽  
Antibacterial And Antifungal

The antibacterial and antifungal activity of zinc(II) carboxylates with composition Zn(RCOO)2•nH2O(R =H-, CH3− , CH3CH2CH2- , (CH3)2CH- , XCH2- , X=Cl, Br, I, n=0 or 2), [ZnX2(Nia+CH2COO-)2] (Nia=nicotinamide, X=Cl, Br, I) and [Zn(XCH2COO)2(Caf)2]•2H2O (Car=caffeine, X=Cl, Br) is studied against bacterial strains Staphylococcus aureus, Escherichia coli and yeast Candida albicans. The structural types are assigned to the prepared compounds and the influence of (i) carboxylate chain length, (ii) substitution of hydrogen atom of carboxylate by halogen and (iii) presence of N-donor organic ligands on the biological activity is discussed.

scholarly journals Comparative assessment of fungicidal activity of widespread wild-growing and endemic species of the Allium genus growing in Tajikistan

2021 ◽  
pp. 55-61
Author(s):  
F. D. Mirzoeva ◽  
S. Satorov
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Endemic Species ◽  
Fungicidal Activity ◽  
Inhibitory Effect ◽  
Comparative Assessment ◽  
Diffusion Method ◽  
Disk Diffusion Method ◽  
Geographical Regions ◽  
The Republic

Aim. To conduct a comparative assessment of the fungicidal activity of widespread and endemic species of the genus Allium growing in Tajikistan.Material and methods. The initial ethanol extracts were obtained from fresh plants of 15 onion species from different climatic and geographical regions of the Republic of Tajikistan. The antifungal activity of species of the genus Allium was studied against the yeast-like fungi Candida albicans using the disk diffusion method.Results: The highest fungicidal effect on the reference strain of Candida albicans was demonstrated by alcoholic extracts of the widespread wild species A. elatum Regel, A. oschaninii O. Fedtsch, A. obliguum L, and endemic species A. shugnanicum Vved. Low antifungal activity was found in extracts of 4 widespread wild-growing plant species - A. altaicum Pall, A. suworowii Regel, A. carolinianum DC, A.longicuspis L.Conclusions. The antifungal activity of 13 species of widespread wild-growing and 2 endemic species (A.shugnanicum Vved and A. pamiricum Wendelbo) was studied for the first time. A. elatum Regel, A. oschaninii O. Fedtsch, A. obliguum L, and endemic species A. shugnanicum Vved had a maximal inhibitory effect on the yeast fungus. The extracts obtained from the bulbs and seeds of the studied plants are characterized by the highest antifungal activity.

scholarly journals SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW SULPHONAMIDES OF PYRIMIDINE

2000 ◽  
Vol 68 (4) ◽  
pp. 333-341 ◽  
Author(s):  
Jerzy Cieplik ◽  
Janusz Pluta ◽  
Olaf Gubrynowicz
Keyword(s):  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Antibacterial And Antifungal Activity ◽  
Antibacterial And Antifungal

The paper presents the synthesis of 5-substituted pyrimidine sulphonamides as well as the results of studies on the antibacterial and antifungal activity of obtained derivatives.

scholarly journals ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF HEDYOTIS CORYMBOSA, INULA RACEMOSE, HOLOSTEMMA ADAKODIEN MEDICINAL PLANTS

2019 ◽  
pp. 25-29
Author(s):  
AJIT KUMAR MARISETTI ◽  
VENKATARATHANAMMA V.
Keyword(s):  
Antifungal Activity ◽  
Medicinal Plants ◽  
Microbial Activity ◽  
Positive Control ◽  
Diffusion Method ◽  
Antibacterial And Antifungal Activity ◽  
Zone Of Inhibition ◽  
Activity Screening ◽  
Antibacterial And Antifungal ◽  
Anti Fungal

Objective: To evaluate the antibacterial and antifungal activity of three different medicinal plants invitro. Oil extracts of the plants from three different families (Hedyotis corymbosa, Inula racemose, Holostemma adakodien) are used to find the antibacterial and antifungal activity. Methods: Study of anti-microbial activity using agar cup diffusion method, inoculums preparation, Anti-bacterial activity screening (well diffusion method), Anti-fungal activity screening (well diffusion method) are the different methods which are used to find the anti-bacterial and anti-fungal activities of the oil extracts of the above medicinal plants. The activity of these oil extracts and the selected antibiotics are evaluated against four bacterial strains (E. Coli, S. aureus and P. aeruginosa) and three Candida fungal strains (albicans, parapsilosis and tropicalis.). The anti microbial activity of Hedyotis corymbosa, Inula racemose, Holostemma adakodien oil extracts zone of inhibition evaluation was compared with positive control of fungal strain Fluconozole and bacterial strain Norfloxacin, Cefepime and Gatifloxacin. Results: The anti microbial activity of Hedyotis corymbosa, Inula racemose, Holostemma adakodien oil extracts zone of inhibition evaluation was compared with positive control of fungal strain Fluconozole and bacterial strain Norfloxacin, Cefepime and Gatifloxacin. Further studies are needed to explore the novel antibacterial bioactive molecules. Conclusion: The plants Hedyotis corymbosa, Inula racemose and Holostemma adakodien have shown significant anti-bacterial and anti-fungal activity.

scholarly journals Synthesis and Antimicrobial Activities of 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives of 5-Amino-2-Hydroxybenzoic Acid

2008 ◽  
Vol 5 (4) ◽  
pp. 963-968 ◽  
Author(s):  
Sabir Hussain ◽  
Jyoti Sharma ◽  
Mohd Amir
Keyword(s):  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Antimicrobial Activities ◽  
Hydroxybenzoic Acid ◽  
Gram Negative Bacteria ◽  
Antibacterial And Antifungal Activity ◽  
Gram Negative ◽  
Thiadiazole Derivatives ◽  
Antibacterial And Antifungal ◽  
Derivatives Of

Various 4-amino-2-[4-(4-substituted phenyl)-5-sulfanyl-4H-1,2,4-triazol-3-yl] phenol (4a-c), 4-amino-2-{4-amino-5-[(4-substituted phenyl)amino]-4H-1,2,4-triazol-3-yl} phenol (5a-c) and 4-amino-2-{5-[(4-substituted phenyl)amino]-1,3,4-thiadiazole-2-yl} phenol (6a-g) were synthesized and evaluated for their antibacterial and antifungal activity. The compounds showed significant antibacterial activity againstS. aureus(gram-positive) andE.coli(gram-negative) bacteria and antifungal activity againstA. nigerfungi using cup plate technique

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