scholarly journals NON-MALIGNANT LESIONS;

2014 ◽  
Vol 21 (01) ◽  
pp. 191-196
Author(s):  
Aftab Ahmed Soomro ◽  
Pirbux Magsi ◽  
Hamid Ali Sangi ◽  
Haresh Chand

Background: The presence of a mass in the nasal cavity and paranasal sinusesmay seem to be simple problem, but it is very difficult to differentiate clinically from potentiallymalignant tumors. Objective: To evaluate the clinical presentation and histopathologicalfeatures of the non malignant lesions of nasal cavity and paranasal sinuses. Study Design:Prospective descriptive study. Place and duration of study: Study was carried out indepartments of Paediatrics and ENT at Ghulam Muhammad Mahar Medical College HospitalSukkur from Jan 2009 to Dec 2012. Patients and Methods: The study included all cases of nonmalignantmasses of nasal cavity and paranasal sinuses, those attended the Paediatric & ENTdepartment and underwent the surgical intervention. One hundred twenty non-malignant caseswere enrolled for this study. A separate pro-forma was filled to record the cases biodata, history,clinical examination, investigations and histopathological diagnosis. All histopathologicallyproven malignant masses were excluded from the study. Results: Out of 120 cases 78 (65%)were males and 42 (35%) were females, with M:F ratio of 1.8:1. The age of presentation rangedfrom 8 years to 70 years and mean age was 26.3years. Sinonasal masses were found to bebilateral in 20 cases (16.67%), right sided in 65 (54.17%) and left sided in 35 (29.16%) cases. Themain presenting symptoms were nasal blockage 110 (91.66%), nasal discharge 102 (85%),sneezing 60 (50%), hypoinsomnia 36 (30%), epistaxis 24 (20%), headache 20 (18.33%) andmouth breathing 18 (15%) cases. Polyp was the most common lesion in 86 (71.66%) casesobserved in this study. The common histopathological diagnosis was simple inflammatory nasalpolyp in 48 (40%), allergic nasal polyps 30 (25%) and fibroepithelial polyp in 8 (6.7%), invertedpapilloma in 12 (10%), angiofibroma 6 (5%), capillary hemangioma 4 (3.34%) andrhinosporidiosis 4 (3.34%) cases. Conclusions: Sinonasal masses have various differentialdiagnoses and are still thought to be simple problem in our society. There is a need for earlyrecognition and referral to ENT surgeon and need histopathological examination of every massto confirm the diagnosis.

2021 ◽  
Vol 8 (33) ◽  
pp. 3054-3059
Author(s):  
Rajendra Prasad Jagannadham ◽  
Lakshmi Latchupatula ◽  
Sravani Ponnada ◽  
Neelima Lalam ◽  
Raghunadhababu Gudipudi ◽  
...  

BACKGROUND A variety of non - neoplastic and neoplastic conditions involve the nasal cavity, paranasal sinuses and nasopharynx and these are very common lesions encountered in clinical practice. Histopathological examination of these lesions is the gold standard for diagnosis because management and prognosis vary among different lesions. The aim of the present study was to evaluate the histopathological study of the lesions of the nasal cavity, paranasal sinuses and nasopharynx in relation to their incidence, age, gender and site wise distribution and to compare the results with the available data. METHODS A study of 88 cases was conducted for a period of 2 years from August 2017 to July 2019. After fixation, Processing and Haematoxylin and Eosin staining and special stains histopathological diagnosis was made. RESULTS Among 88 total cases, 58 were males and 30 were females. A male predominance was observed with a male to female ratio of 1.93 : 1. They were more common in third, fourth and fifth decade of life. Malignant nasal lesions were seen after fourth decade of life. Nasal lesions were more common in nasal cavity (67.05 %), followed by paranasal sinuses (18.18 %) and nasopharynx (14.75). Out of 88 total cases, 39 (44.32 %) were non - neoplastic, 30 (34.09 %) were benign and 19 (21.59 %) were malignant nasal lesions. CONCLUSIONS Sinonasal lesions and nasopharyngeal lesions can have various differential diagnoses. A complete clinical, radiological and histopathological correlation helps to categorize these sinonasal lesions into various non - neoplastic and neoplastic types. But histopathological examination remains the mainstay of definitive diagnosis. KEYWORDS Nasal Cavity, Paranasal Sinuses, Nasopharynx, Benign Tumours, Malignant Tumours, Histopathological Examination


2021 ◽  
Vol 28 (3) ◽  
pp. 193-197
Author(s):  
Devika T ◽  
Shubha P Bhat ◽  
Vadisha Srinivas Bhat ◽  
Rajeshwary Aroor ◽  
Satheesh Kumar Bhandary B ◽  
...  

Introduction Mass in the nasal cavity presents with a wide range of symptoms, when a presumptive diagnosis is often made with the help of imaging and endoscopy. This study focussed on correlating clinical diagnosis with the histopathological diagnosis so that appropriate treatment can be offered to improve the quality of life of the patient. Materials and Methods The study included 120 cases who presented with symptoms and signs of mass in the nasal cavity, undergoing surgery or diagnostic biopsy. They were evaluated with a detailed history and clinical examination, diagnostic nasal endoscopy, and relevant radiological investigations. Histopathological examination of the biopsy of the excised specimen was performed by Haematoxylin and Eosin stain. Special stains and Immunohistochemistry (IHC) were performed whenever indicated. The clinical diagnosis was correlated with histopathological diagnosis. Results Nasal obstruction was the most frequent symptom followed by nasal discharge. Non-neoplastic lesions made up 85% of cases, while16% of cases were proved as neoplastic lesions. Among neoplastic lesions, 7% were benign, and 9% were malignant.  The inflammatory polyp was the most common non-neoplastic lesion. Fischer's exact test showed a correlation between clinical diagnosis and histopathological diagnosis. Non-neoplastic lesions were common in the 4th decade of life; benign lesions were common in the 3rd decade of life, while malignant lesions were common in the 5th decade of life. Conclusion Sinonasal masses present with overlapping clinical features, and sometimes the definite diagnosis is possible only by histopathological examination of the specimen. However, in the presence of characteristic clinical features, accurate clinical diagnosis is possible in most cases, and appropriate treatment can be performed without delay, pending histopathological examination.


Author(s):  
Belure Gowda P. R. ◽  
Vinay Kumar M. V.

<p class="abstract"><strong>Background:</strong> Masses in sino nasal cavity presents with wide range of complaints like nasal obstruction, nasal discharge, epistaxis, headache, swelling in and around the nose, through clinical examination, rigid nasal endoscopy and by use of advanced imaging technique computerized tomography (CT), magnetic resonance imaging (MRI) of nose and paranasal sinuses. Presumptive diagnosis is often made. However, it is a careful histopathological examination which divides the nature of any particular lesion, like neoplastic benign or malignant or  non-neoplastic and inflammatory which makes possible to implement correct and timely intervention, which is a major dividing factor for better prognosis.</p><p class="abstract"><strong>Methods:</strong> A total of 100 cases of nasal polyps were studied by the department of ENT at Hassan institute of medical sciences, Hassan during a period of 1 year from January 2019 to January 2020. They were treated surgically by endoscopic excision, lateral rhinotomy or by radical surgery. All the excised masses were sent for histopathological examination to determine their final diagnosis.</p><p class="abstract"><strong>Results:</strong> The middle age group of 21 to 30 years was the most common age group affected with more male predominance. Nearly 85% of the cases were non-neoplastic. The most common presentation was nasal obstruction with ethmoidal sinus being the commonest sinuses seen in the present study.</p><p class="abstract"><strong>Conclusions:</strong> Polypoid lesions in the nasal cavity and paranasal sinuses may range widely from benign to malignant affecting all the ages. Common nasal lesions were seen in age group 21-30 years and maximum lesions were non- neoplastic.</p>


2017 ◽  
Vol 10 (1) ◽  
pp. 39-41
Author(s):  
Sumit Prinja ◽  
Jai L Davessar ◽  
Heera Luthra

ABSTRACT Introduction An inverted papilloma is a benign tumor that is found in the nasal cavity or paranasal sinuses. Inverted papilloma accounts for approximately 0.5 to 2.0% of all nasal tumors. While it is considered benign, an inverted papilloma can destroy the surrounding bone. In a small number of cases (5-15%), an inverted papilloma may be found with a squamous cell carcinoma; one such case is reported. Case report A 70-year-old male presented with complaints of right-sided nasal blockage, which progressively increased over time and nasal discharge since one and half years with occasional history of epistaxis. On anterior rhinoscopic examination, there was a fleshy polypoidal mass filling the right nasal cavity. Contrast-enhanced computed tomography revealed a soft tissue density mass filling maxillary sinus and posterior choana with mild enhancement. Endoscopic medial maxillectomy was performed with complete removal of mass. Histopathological diagnosis was given as inverted sinonasal papilloma with malignant transformation. The patient was referred to a cancer reference center for treatment and received combined radiotherapy and chemotherapy. Patient was disease free at 6-month follow-up. Conclusion An inverted papilloma is a benign tumor with a propensity for malignant change. For these reasons, inverted papilloma should be treated like malignant tumor of the nasal cavity and paranasal sinuses. How to cite this article Prinja S, Davessar JL, Luthra H, Kaur M. Ringertz Tumor with Malignant Transformation. Clin Rhinol An Int J 2017;10(1):39-41.


2019 ◽  
Vol 49 (20) ◽  
Author(s):  
Nugroho Suharsono

Background: Fungal infection of the nose and paranasal sinuses is an uncommon condition which is now being increasingly recognized. The clinical presentation is not specific with various symptoms such as nasal obstruction, purulent nasal discharge, facial pain, and chronic cough. Only unilaterality may alert the clinician. Purpose: To find the morphological characteristics of the fungus in patients with paranasal sinus fungus ball. Methods: A retrospective study of 13 paranasal sinus fungus balls cases which underwent endoscopic sinus surgery at Department of Otorhinolaryngology Head and Neck Surgery St. Vincentius A Paulo Hospital Surabaya from March, 2012 until December, 2013. Age, sex, histopathology and fungal cultur were analysed. Histopathologic sections of all the patients were stained with hematoxylin and eosin (H&E), and Gomori methenamine silver (GMS). The specimens were then cultured on Sabouraud dextrose agar plates and incubated at 30°C for 1 month. At the end of the incubation period, the samples were evaluated microscopically to detect fungi and identify their species. Results: The age reported of the 13 patients, was ranging from 36 to 63 years old. There was a significant female predominance, 10 female patients (76.92%) and 3 male patients (23.08%). Histopathological examination showed that most causative agents were Aspergillus species 92.31% (12/13). Culture test was positive for 69.23% (9/13). Aspergillus niger (61.54%, 8/13) is the most frequent fungus reported to cause fungus balls. Conclusion: Pattern of histopathologic on HE and GMS is very helpful and sensitive to identify fungi. The most common isolated mould in our study was Aspergillus niger.Keywords: fungus ball, histopathology and culture, Aspergillus nigerABSTRAK Latar Belakang: Infeksi jamur di hidung dan sinus paranasal merupakan kondisi yang jarang terjadi, namun kini lebih sering ditemukan. Gejala klinisnya tidak spesifik dapat berupa obstruksi hidung, sekret dari hidung, nyeri wajah, dan batuk kronis. Bila terjadi unilateral, patut diwaspadai oleh para klinisi. Tujuan: Untuk mengetahui karakteristik morfologi fungus yang didapati pada pasien sinusitis jamur yang kami teliti. Metode: Dilakukan penelitian retrospektif pada 13 pasien sinusitis jamur yang menjalani bedah sinus endoskopi di Departemen Otorinolaringologi-Kepala Leher Rumah Sakit St. Vincentius A Paulo Surabaya dari bulan Maret 2012 sampai dengan Desember 2013. Dilakukan analisis usia, jenis kelamin, histopatologi dan kultur jamur. Pewarnaan preparat histopatologi menggunakan Hematoxylin dan eosin (H&E) dan Gomori Methenamine Silver (GMS). Kemudian spesimen diletakkan pada piring agar Sabouraud dextrose, dan dilakukan inkubasi pada suhu 30°C selama satu bulan. Pada akhir masa inkubasi, sampel dievaluasi dengan mikroskop untuk mendeteksi jamur dan spesiesnya. Hasil: Didapati usia 13 penderita berkisar dari 36-63 tahun. Wanita lebih dominan sebanyak 10 penderita (76,92 %) dan 3 penderita laki-laki (23,08%). Hasil pemeriksaan histopatologi menunjukkan spesies Aspergillus sebagai penyebab utama (92,31%) pada 12 penderita (12/13).Tes kultur positif pada 69,23% (9/13). Jamur yang paling sering menyebabkan bola jamur pada sinus adalah Aspergillus niger (61,54%, 8/13). Kesimpulan: Pewarnaan preparat histopatologi menggunakan Hematoxylin dan eosin (H&E) dan Gomori Methenamine Silver (GMS) sangat berguna dan sensitif dalam mendeteksi adanya jamur. Jenis jamur yang paling banyak ditemukan pada penelitian kami adalah Aspergillus niger.


2014 ◽  
Vol 7 (2) ◽  
pp. 76-79
Author(s):  
Vishal Prasad ◽  
Chandrakala Srinivas ◽  
Sheetal Krishnappa ◽  
Suresh T Narayan Rao ◽  
Harshitha T Rajanna

ABSTRACT Objective To highlight an interesting and a rare case of two rhinoliths in a single nasal cavity of an elderly male patient, mimicking fungal sinusitis or malignancy. To emphasize that rhinolith has to be considered in the differential diagnosis of unilateral nasal mass even in the elderly. Case report A 55-year-old man presented with a right-sided nasal obstruction, foul-smelling nasal discharge and a mass in the right nasal cavity of 6 months duration. Endoscopic examination revealed a gritty, blackish brown mass filling the entire right nasal cavity. A clinical differential diagnosis of malignancy or fungal sinusitis was made. CT scan of paranasal sinus was suggestive of fungal sinusitis following which patient was posted for biopsy. Intraoperatively, patient was found to have two separate masses in the right nasal cavity which were removed. We found a septal perforation adjoining the area where the rhinolith was impacted, with septum pushed laterally and adherent to middle turbinate. However, there were no features suggestive of malignancy. Histopathological examination also ruled out malignancy and confirmed a vegetable foreign body with calcification around an acellular material. Conclusion Rhinolith, though rare should be considered in the differential diagnosis of unilateral nasal mass in the elderly. How to cite this article Prasad V, Srinivas C, Krishnappa S, Rao STN, Rajanna HT. Two Rhinoliths in a single nasal Cavity in an Elderly Patient Mimicking fungal sinusitis. Clin Rhinol An Int J 2014;7(2):76-79.


Author(s):  
Rajat Sharma ◽  
Dimple Sahni ◽  
Kuljeet Uppal ◽  
Rajeev Gupta ◽  
Gifty Singla

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">A variety of inflammatory, non neoplastic and neoplastic masses involving nasal cavity, paranasal sinuses and nasopharynx are commonly encountered in ENT clinics. The objective was to study the demographic profile, clinical presentation, radiological findings and its correlation with the histopathological findings of masses of nasal cavity, paranasal sinuses and nasopharynx. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The study was conducted on patients having sinonasal and nasopharyngeal masses admitted in dept of ENT, GMC, Patiala from August 2014 to July 2016. The study was designed to evaluate demographic distribution, clinicopathological features, radiological findings of sinonasal and nasopharyngeal masses and to evaluate the correlation of clinical and radiological findings with histopathological diagnosis.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Analysis of 50 cases of masses in nasal cavity, paranasal sinuses and nasopharynx was done. Male to female ratio was 1.38:1. The commonest site was nasal cavity followed by paranasal sinuses. Nasal polyp was the most common non-neoplastic lesion. Among the neoplastic lesions studied, inverted papilloma was the most common benign lesion and squamous cell carcinoma was the most common malignant lesion observed. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">For proper evaluation of sinonasal and nasopharyngeal masses, clinical, radiological and histopathological evaluation should be done in all patients. Although radiology provides a road map to endoscopic surgeons for any existing or impending complications but histopathology always gives a confirmatory diagnosis.</span></p>


2021 ◽  
Vol 6 (4) ◽  
pp. 259-266
Author(s):  
Ankita Sunil Chaudhari ◽  
Shivaji Dadarao Birare

Sinonasal masses are common in the ENT Outpatient Department. The incidence being 1-4% of population. The symptoms and signs frequently overlap, hence, a diagnostic dilemma exists. The aim of this study was to study the occurrence of various lesions, the age, site and sex wise distribution in a tertiary care hospital of Maharashtra over the period of two years. The study aims to examine the occurrence of various lesions in nasal cavity and paranasal sinuses, to determine the age, sex and site wise incidence of different benign and malignant lesions of nasal cavity and paranasal sinuses and to correlate the clinical and histopathological findings. Descriptive Study A descriptive study was carried out in the Department of Pathology at Tertiary Health Care among patients with clinically diagnosed nasal and paranasal sinus lesions attending the OPD of ENT during a period of 2 years. The specimens were grossly examined; fixed and routine microscopic staining was done. Interpretation was done using colour of the nuclei and the specimens were classified as neoplastic and non-neoplastic lesions. The data was statistical analysed. Mean, Median, Mode The most common clinical presentation was nasal obstruction 97 (93.26%), rhinorrhoea 73 (70.19%) and facial pain 24 (23%). 1: Mean age for the lesions to occur was years with the range 21-30 years (20.92%); 2: Non-neoplastic lesions 82 (79.6%) were more common than neoplastic lesions; 3: Simple nasal polyp 74 (90.23%), hemangiomas (50%) and squamous cell carcinoma (50%) were most common. The study concludes that complete clinical, radiological and histopathological correlation helps us to categorize these sino-nasal lesions into various non-neoplastic and neoplastic types. But final histopathological examination provides a confirmatory diagnosis, as a significant number of cases may be missed on clinical evaluation alone.The clinical features of non-neoplastic and neoplastic nasal and paranasal sinuses lesions may be indistinguishable from each other leading to delay in proper diagnosis and treatment. Histopathological examination is a reliable, cost effective diagnostic tool for accurate diagnosis and management of such lesions, as a significant number of cases may be missed on clinical evaluation alone.


2015 ◽  
Vol 30 (2) ◽  
pp. 39-42 ◽  
Author(s):  
Fernanda de Assis B. Auler ◽  
Luciana N. Torres ◽  
Ana Carolina B.C.F. Pinto ◽  
Silvana M. Unruh ◽  
Julia M. Matera ◽  
...  

2019 ◽  
pp. 60-65 ◽  
Author(s):  
S. V. Morozova ◽  
L. A. Toporkova

One of the main functions of the nose is respiratory and olfactory. Difficulty in nasal breathing, nasal congestion, nasal discharge can complicate the respiratory and olfactory functions of the nose or make them impossible. Most often the cause is swelling of the mucous. Nasal obstruction and rhinorrhea are the most common symptoms in diseases of the nasal cavity and paranasal sinuses. Of great importance is the use of local vasoconstrictors to eliminate swelling in the nasal cavity and prevent complications associated with auditory tube dysfunction. It is proved that the use of nasal decongestants helps to reduce swelling in the nasal cavity and in the osteomeatal complex. Otrivin Moisturizing formula, Otrivin Menthol, Otrivin Complex and Otrivin Sea are effective and well tolerated means to eliminate swelling in the nasal cavity and reduce nasal discharge and rehabilitation of olfactory function.


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