scholarly journals Protective effect of zingiber officinale on mobile phone induced rat brain injury.

2021 ◽  
Vol 28 (12) ◽  
pp. 1797-1803
Author(s):  
Syed Alamdar Raza Zaidi ◽  
Mohammad Fawad Saeeduddin ◽  
Aisha Qamar ◽  
Shabnam Khan ◽  
Rozina Khan ◽  
...  
Keyword(s):  
Body Weight ◽  
Protective Effect ◽  
Mobile Phone ◽  
Rat Brain ◽  
Zingiber Officinale ◽  
Control Group ◽  
Final Body Weight ◽  
Group B ◽  
3G Mobile Phone ◽  
Group D

Objective: To observe the protective effect of zingiber officinale against radio frequency (RF) radiation-induced oxidative stress on rat brain due to 3G mobile phone. Study Design: Prospective Experimental study. Setting: Department of Anatomy, BMSI, JPMC, Karachi. Period: January to March 2018. Material & Methods: Twenty four healthy, adult, Albino rats, 3-4 months of age, weighing 150-300 gm were acquired. They were sorted into four groups. Group A was marked as control, Group B was exposed to 3G mobile phone 2100MHz radiation 24 hours daily, Group C was exposed to same dose of radiation as group B along with zingiber officinale 250mg/kg/day orally, and Group D was given same dose of zingiber officinale as in group C. The rats were euthanized at end of study period after recording their final weight. Brain of rats was removed and weighed. It was processed for haematoxylin and eosin stain to observe general morphology of cerebellum. Results: The data displayed an insignificant increase in final body weight and absolute brain weight in group B animals as compared to control, whereas an insignificant increase and insignificant decrease was observed in body weight and absolute weight of brain when group C was compared with group B respectively. Microscopic examination of cerebellum in H & E stained sections revealed distortion of cellular architecture in group B as compared to control. Tissue sections from group C demonstrated significant restoration of cerebellar architecture. Results of group D were similar to control. Conclusion: Cell phones emit radiation causing damage to brain, especially cerebellum, however, concurrent use of ginger significantly ameliorates this damaging effect.

scholarly journals Effects of aqueous leaf extract of Corchorus olitorius on the testis and blood testosterone level of adult Wistar rats

2021 ◽  
Vol 10 (2) ◽  
pp. 024-030
Author(s):  
Godwin Chinedu Uloneme ◽  
Demian Nnabuihe Ezejindu ◽  
Darlington Cyprian Akukwu ◽  
Amadi Chibundu Chiekezie
Keyword(s):  
Body Weight ◽  
Wistar Rats ◽  
Day Treatment ◽  
Control Group ◽  
Corchorus Olitorius ◽  
Group A ◽  
Normal Rat ◽  
Group B ◽  
Calcium Iron ◽  
Group D

Background: The extract of Corchorus olitorius has a reasonable content of vitamins A and C, calcium, iron and fibre, and therefore enjoys a universal application in the treatment of some disease conditions, even as the whole leaf is a very important component of food in so many cultures. Purpose: The study was designed to investigate the effect of Corchorus olitorius extracts on the testis of adult Wistar rats. Method: A total number of thirty two adult Wistar rats weighing between 180 and 200 grammes separated into four groups labeled A,B,C and D respectively were used for the study. Animals in group A which served as the control group were fed with the normal rat chow and water only. The group B rats were administered 100mg/kg body weight of aqueous extract of Corchorus olitorus; while those in group C were administered 500mg/kg body weight of the extract. The group D rats received 1000mg/kg body weight of the extract. For a period of four weeks, the different experimental animal groups received the respective aforementioned treatments once daily, around nine- o’clock in the morning through oral intubation. At the end of the 28 day treatment, the animals were sacrificed and the testes harvested for histological, investigation, and through cardiac puncture, blood samples for some hormonal studies was also collected and investigated using standard laboratory standards. Results: Observations made showed that the extract produced no histological distortions, degenerative or defective effects on the testicular tissues. The testosterone levels of group B, C, and D rats were observed to be significantly higher (P<0.005) than that of the group A (control group).ound: The extract of Corchorus olitorius has a reasonable content of vitamins A and C, calcium, iron and fibre, and therefore enjoys a universal application in the treatment of some disease conditions, even as the whole leaf is a very important component of food in so many cultures. Purpose: The study was designed to investigate the effect of Corchorus olitorius extracts on the testis of adult Wistar rats. Method: A total number of thirty two adult Wistar rats weighing between 180 and 200 grammes separated into four groups labeled A,B,C and D respectively were used for the study. Animals in group A which served as the control group were fed with the normal rat chow and water only. The group B rats were administered 100mg/kg body weight of aqueous extract of Corchorus olitorus; while those in group C were administered 500mg/kg body weight of the extract. The group D rats received 1000mg/kg body weight of the extract. For a period of four weeks, the different experimental animal groups received the respective aforementioned treatments once daily, around nine- o’clock in the morning through oral intubation. At the end of the 28 day treatment, the animals were sacrificed and the testes harvested for histological, investigation, and through cardiac puncture, blood samples for some hormonal studies was also collected and investigated using standard laboratory standards. Results: Observations made showed that the extract produced no histological distortions, degenerative or defective effects on the testicular tissues. The testosterone levels of group B, C, and D rats were observed to be significantly higher (P<0.005) than that of the group A (control group).

scholarly journals EFFECT OF KALO JEERA SEEDS AND PAPAYA LEAF SUPPLEMENTATION ON THE PERFORMANCE OF BROILER

2016 ◽  
Vol 14 (1) ◽  
pp. 37-42 ◽  
Author(s):  
M. G. Sorwar ◽  
M. Mostofa ◽  
M. N. Hasan ◽  
M. Billah ◽  
M. T. Rahman
Keyword(s):  
Body Weight ◽  
Treatment Group ◽  
Nigella Sativa ◽  
Control Group ◽  
Growth Promoter ◽  
Final Body Weight ◽  
Live Body Weight ◽  
Significant Difference ◽  
Group A ◽  
Group B

This experiment was conducted to determine the effect of papaya leaf (Carica papaya) and kalo jeera (Nigella sativa) seeds powdered supplementation in drinking water as a growth promoter in broiler chickens. A total of 20 Cobb-500 broiler chicks (day-old) were purchased from local hatchery (Nourish Poultry and Hatchery Ltd.) and after seven days of acclimatization chicks were randomly divided into two groups, A (n=10) and B (n=10). The group A was kept as a control and not treated. The group B was supplemented with papaya leaf and kalo jeera powder with feed and water. Weekly observations were recorded for live body weight gain up to 5th weeks and hematological tests were performed at 35th day’s age of broiler to search for hematological changes between control (A) and treatment (B) groups. The initial body weight of groups A and B on 1st were 41.00±0.56 gm and 41.50±0.35 gm, respectively and after 35th day of experiment final body weight were 1470±57.35 gm and 1720±58.56 gm, respectively and economics of production were analyzed and found that net profit per broiler was Tk. 8.91 and Tk. 20.69, respectively. The treatment group B was recorded statistically significant (at 1% level) increased (17.00%) for live body weight than that of control group A. The hematological parameters total erythrocyte count (TEC), erythrocyte sedimentation rate (ESR) and hemoglobin (Hb) estimation value of treatment group shows significant difference, while hemoglobin estimation does not show significant difference from control group. The results suggest that better growth performance could be achieved in broilers supplemented with papaya leaf and kalo jeera seeds.

scholarly journals Growth rate and acid-base balance in turkeys fed a silage-containing diet modified by different dietary cation-anion difference

2017 ◽  
Vol 73 (12) ◽  
pp. 786-791
Author(s):  
Kamil Gruszczyński ◽  
Wacław Strobel ◽  
Marta Wójcik ◽  
Urszula Kosior-Korzecka ◽  
Joanna Wessely-Szponder ◽  
...  
Keyword(s):  
Body Weight ◽  
Body Weight Gain ◽  
Diet Group ◽  
Control Group ◽  
Standard Diet ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
Group B ◽  
Group D

The aim of the study was to find the responses of acid-base parameters and performance parameters of turkeys to a corn silage (CS) diet with different values of the dietary cation-anion difference (DCAD). The turkeys were fed as follows: group A (control) – standard diet (SD) (60%) plus CS (40%); group B – SD (60%), CS (40%) plus 240 g of CaCl2 per100 kg of diet; group C – SD (60%), CS (40%) plus 480 g of CaCl2 per 100 kg of diet; group D – SD (60%), CS (40%) plus 240 g of NaHCO3 per 100 kg of diet; group E – SD (60%), CS (40%) plus 480 g NaHCO3 per 100 kg of diet. The addition of the smaller amount of CaCl2 reduced DCAD, which ranged between 49.75 ± 6.29 mEq/kg DM and 93.56 ± 3.34 mEq/kg DM. An increased content of CaCl2 led to high, negative values of DCAD. NaHCO3 supplemented in both doses resulted in a significant elevation of DCAD. The addition of CS to the SD led to a lower body weight in comparison to that in the B, C, D and E groups. Forage acidification and alkalization improves body weight gain (BWG) at every stage of feeding. Compared to the control group, the anion gap was insignificantly lower in birds exposed to the acidic diet, and was comparable to the decrease in HCO3 –. Conversely, the addition of NaHCO3 to the diet led to a marked elevation in HCO3 – to 29.63 ± 0.4 mEq/L in group D and to 30.3 ± 0.69 mEq/l in group E. In conclusion, a change in DCAD during the feeding of forage containing CS exerts stimulatory effects on productive parameters of turkeys....

scholarly journals Anti-hyperglycemic Effects of Diacerein in Alloxan-Induced Diabetes Mellitus in Wistar Albino Rats

2020 ◽  
pp. 107-113
Author(s):  
Arsalan Uqaili ◽  
Samia Siddiqui ◽  
Roomi Aijaz ◽  
Yar Muhammad Nizammani ◽  
Navaid Kazi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Blood Glucose ◽  
Treated Group ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Control Group ◽  
Albino Rats ◽  
Group B ◽  
Group D

Objective: To determine the anti-hyperglycemic effects of interleukin-1 inhibitor (diacerein) in alloxan induced diabetic albino wistar rats. This experimental study was performed at the Department of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tando Jam within 6 months from April 2016 to September 2016. Total of 160 adult Albino Wistar Rats having an average of 200 to 300 grams body weights were selected. Animals were categorized into 4 groups as; Group A (n=15): Control rats – receive 0.9% normal saline as placebo Experimental Groups Group B (n=15): Experimental Control (Diabetic rats) - Alloxan50 mg/kg body weight intraperitoneal. Group C (n=15): Diabetic rats + Diacerein (30 mg/kg/day) orally daily. Group D (n=15): Diabetic rats + Diacerein (50 mg/kg/day) orally daily. Animals were kept and treated as per the NIH Guideline for Use and Care of Laboratory Animals. Diabetes mellitus was induced via a single intraperitoneal injection of 50 milligram/kg alloxan monohydrated dissolved in aseptic 0.9% saline. After 72 hours, blood specimens were taken from the caudal vein of the rats and glucose level>200 mg/dL was taken as diabetes. Experimental rats were given diacerein approximately 30 and 50 mg orally for 6 weeks. At the completion of experiment the body weight was measured of each animal by electronic measuring balance and blood sample was taken from each animal of all groups to assess the blood glucose level and HbA1c level. Data were recorded via self-made proforma and analysis was done by using SPSS version 20. Results: Average body weight of Diabetic control (Group B) was 193.33±22.50 grams, which was lower in contrast to Diacerein treated group C 202.47±25.70 grams and significantly lower as compared to Diacerein treated group D as  212.6±23.43 grams. A significant increase in blood glucose levels 182.07±10.63 mg/dl was noted in the Diabetic control (Group B) compared to Diacerein treated group C (110.13± 8.54 mg/dl) and group D (85.87±8.41 mg/dl) (P=0.001). HbA1c was markedly raised in the Group B- diabetic controls, while diacerein treated diabetic rats (groups C and D) showed a significant decrease in HbA1c (P=0.001). Conclusion: It was concluded that Diacerein achieves the Euglycemic state by reducing the levels of blood glucose and glycated hemoglobin (HbA1c) in Alloxan-Induced diabetes mellitus in Wistar Albino Rats.

scholarly journals Protective Effect of Curcuma Longa (Turmeric) on Serum Aspartate Aminotransferase and Lactate Dehydrogenase in Isoproterenol Induced Myocardial Injury in Rats

2019 ◽  
Vol 47 (3) ◽  
pp. 13-17
Author(s):  
Sharmin Nahar ◽  
Qazi Shamima Akhter ◽  
Mahmuda Nasrin Shumi ◽  
Noor E Jannat Tanvi ◽  
Nahid Yeasmin ◽  
...  
Keyword(s):  
Body Weight ◽  
Lactate Dehydrogenase ◽  
Myocardial Injury ◽  
Curcuma Longa ◽  
Control Group ◽  
Final Body Weight ◽  
Serum Aspartate Aminotransferase ◽  
Group A ◽  
The Mean ◽  
Group B

Cardiovascular diseases (CVDs) emerging as a major health problem in Bangladesh due to increase prevalence of risk factors. Conventional cardioprotective drugs are effective but expensive and associated with a number of side effects. Curcuma longa is an important source of traditional medicine for the prevention and treatment of CVDs. The objective of the study was to evaluate the protective effect of Curcuma longa on isoproterenol induced myocardial injury in rats. This experimental study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during 2015. Total 21 Wistar albino male rats, aged 85 to 100 days, weighing 100 to 150 g (initial body weight) were selected for the study. After acclimatization for 14 days, the rats were divided into three groups. Group A (base line control group), Group B (isoproterenol treated control group) and Group C (Curcuma longa pretreated and isoproterenol treated group). Each group consisted of 7 rats. On the 10th day of experiment, rats were sacrificed after taking final body weight. Blood samples were collected from the heart. Serum aspartate aminotransferase (AST) level was estimated by Colorimetric method and lactate dehydrogenase (LDH) level was estimated by ELISA method. The statistical analysis was done by one way ANOVA and Bonferroni test as applicable.  In this study, the mean initial and final body weight of the rats were almost similar and showed no statistically significant difference among the groups. The mean serum AST and LDH levels were significantly (P<0.001) higher in Group B than those of Group A. Again, these levels were significantly (P<0.001) lower in Group C than those of Group B group. From the results, it can be concluded that Curcuma longa has cardioprotective activity on isoproterenol induced myocardial injury in Wistar albino rats. Bangladesh Med J. 2018 Jan; 47 (3): 13-17

Effects of Ganoderma Lucidum and Krestin on Subset T-cell in Spleen of γ-irradiated Mice

1995 ◽  
Vol 23 (03n04) ◽  
pp. 289-298 ◽  
Author(s):  
Wang-Chi Chen ◽  
Dou-Mong Hau ◽  
Chih-Chung Wang ◽  
I-Hsin Lin ◽  
Shiuh-Sheng Lee
Keyword(s):  
Body Weight ◽  
Ganoderma Lucidum ◽  
Radiation Treatment ◽  
Whole Body ◽  
Control Group ◽  
Γ Irradiation ◽  
Group A ◽  
Group B ◽  
Group D ◽  
Better Than

Effects of Ganoderma lucidum (Gl) and Krestin (PSK) extracts on spleen, thymus and splenocytes in γ-irradiated mice were investigated in this study. ICR strain male mice were divided into five groups. Group A was the normal control. Group B, the experimental control, was treated with Gl. Group C, the radiation treatment control, was treated with whole body exposure to 4 Gy γ-irradiation (RT). Group D was treated with RT and Gl. Group E was treated with RT and PSK. The dosage of Gl was 400 mg/day/kg body weight and PSK was 500 mg/day/kg body weight. Our results indicated that the relative thymus weight in groups D and E were higher than group C on day 28 after γ-irradiation. Group D was the highest in all the experimental groups. CD4 and CD8 splenocytes in group D were higher than group C on days 7 and 28. Gl was better than PSK in repairing the damage of subset T-cells in the spleen of γ-irradiated mice.

scholarly journals Efficacy of Kalo Jeera seeds (Nigella sativa) and Thankuni (Centella asiatica) supplementation on the growth performance of broiler chicken

2015 ◽  
Vol 1 (4) ◽  
pp. 196
Author(s):  
Chandan Kumar Sarkar ◽  
Mahbub Mostofa ◽  
Md. Mahmudul Hasan Sikder ◽  
Wahedul Karim Ansari ◽  
Md. Mostakin Ahamed ◽  
...  
Keyword(s):  
Growth Rate ◽  
Body Weight ◽  
Treatment Group ◽  
Growth Performance ◽  
Nigella Sativa ◽  
Centella Asiatica ◽  
Control Group ◽  
Growth Promoter ◽  
Final Body Weight ◽  
Group B

<p class="abstract"><strong>Background:</strong> In modern era, treatment methods become diversified and developed day by day and organic medicine is one of the modern technology which also introduced in our poultry sector.<strong> </strong>This experiment was conducted to evaluate the efficacy of Thankuni (<em>Centella asiatica)</em> and Kalo Jeera (<em>Nigella sativa</em>) powdered supplementation as a growth promoter in broiler chickens.</p><p class="abstract"><strong>Methods:</strong> A total of 20 day-old Cobb 500 broiler chicks were randomly divided into two groups, A and B after seven days of acclimatization. The group A was kept as control and fed on only normal balanced diet. The group B was treatment group fed on normal diet with additional supplementation of Thankuni and Kalo Jeera powder in water. For observation of growth rate, live body weight was taken at first day and every seven days interval up to 5<sup>th</sup> weeks. Besides it hematological tests were performed at 35<sup>th</sup> days for searching hematological changes in both groups.  </p><p class="abstract"><strong>Results:</strong> The initial body weight of groups A and Bon 1<sup>st</sup> day of this experiment were 43.00 ± 0.56 gm and 42.50 ± 0.35 gm, respectively and after 35<sup>th</sup> day of experiment final body weight were 1450 ± 57.35 gm and 1700 ± 58.56 gm (p&lt;1%) respectively. The growth rate of treatment group B was 17.24% more (p&lt;1%) than that of control birds. Although the dressing percentage of both group was equal but relative weight of heart, liver, spleen and pancreas were significantly higher (p&lt;0.1) in treatment group indicates better flock health. Feed Conversion Ratio (FCR) were 1.88 in treated birds and 2.28 in control birds was the sign of economy rate of production and were analyzed and found that net profit per broiler was Tk. 10.50 (0.12 USD) and Tk. 33.00 (0.4 USD), respectively. General blood parameters of treatment group were non-significantly higher than control group.  </p><strong>Conclusions:</strong> The results suggest that better growth performance were achieved in broilers supplemented with Thankuni leaf and Kalo Jeera. Both of these two herbal medicines have antimicrobial, immunostimulatory, anti-stress, fungi static, insecticidal and liver tonic properties so that there were no mortality rate. Now it can be said that uses of Thankuni and Kalo Jeera has beneficiary effects in broiler production.

scholarly journals Effect of Fenugreek (Methi) on the Thymic volume in Streptozotocin-induced Diabetic Rats

1970 ◽  
Vol 16 (1) ◽  
pp. 1-4
Author(s):  
DK Mondal ◽  
MM Karim ◽  
S Mohal ◽  
BMA Yousuf ◽  
KM Shamim
Keyword(s):  
Body Weight ◽  
Treated Group ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Diabetic Group ◽  
Control Group ◽  
Final Body Weight ◽  
Diabetic Control Group ◽  
Group A ◽  
Group B

Effect of fenugreek (Trigonella foenumgraecum) on thymic volume was studied in 30 long Evansrats. Among the total, 10 were treated with only vehicle (non-diabetic control - group A); 10 weretreated with streptozotocin only (diabetic control - group B) and 10 were treated with fenugreek(fenugreek treated - group C). Mean relative thymic volumes were 0.22210.018 ml/100 gm ofcorresponding final body weight (Mean 1 SEM), 0.14710.015 and 0.19910.020 in group A, B and Crespectively. In non-diabetic control group the thymic volume was significantly higher (p=0.005)than that of diabetic control group. In fenugreek treated diabetic group the volume was alsosignificantly higher (p=0.05) from that of diabetic control group and very much nearer to nondiabeticcontrol group (p=0.398). Fenugreek may preserve the thymic volume considerably indiabetic rats.doi: 10.3329/taj.v16i1.3892TAJ June 2003; Vol.16(1): 1-4

scholarly journals Effects of ginger juice on blood glucose in alloxan induced diabetes mellitus in rats

2015 ◽  
Vol 23 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Selima Sultana ◽  
Md Ismail Khan ◽  
Hasanur Rahman ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Rokhsana Dil Afroz
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Zingiber Officinale ◽  
Control Group ◽  
Fasting Blood Glucose Level ◽  
Medical College ◽  
Group D

Objective: To find out the effects of ginger (Zingiber officinale) juice blood glucose in alloxan induced-diabetes mellitus in rats. Methods: This experimental study was done in the Department of Pharmacology & Therapeutics, Dhaka Medical College, Dhaka, in collaboration with the Departments of Pathology, Ibrahim Medical College, Dhaka between January and December 2009. This experimental animal study was divided into two parts, which were Experiment-1 and Experiment-2. Experiment 1 comprises of 12 rats and divided into 2 groups each group having 6 rats. Rats of group-A was non-diabetic normal control group and group-B was fed with ginger (Zingiber officinale) in a dose of 4ml/kg body weight orally through Ryle’s tube. Experiment-2 comprised of 12 rats divided into 2 groups each containing 6 rats labeled as group C, group D. Rats of groups C administered alloxan 150 mg/kg intraperitoneally on the 2nd day of the study. Rats of group D were administered alloxan 150mg /kg intraperitoneally and ginger (4ml/kg of body weight orally) on the 2nd day of the study. Results: The fasting blood glucose level at day 12 in the rats treated with ginger (Zingiber officinale) 4 ml /kg body weight orally daily for 12 days showed reduction in fasting blood glucose level as compared to control group, but not significant, which indicates that ginger has no effect in lowering blood glucose of normal rats. The fasting blood glucose levels at day 12 in the rats of group D (treated with ginger and alloxan) showed highly significant reduction in fasting blood glucose level as compared to diabetic control group (p<0.002). Conclusion: Consumption of ginger produced a significant antihyperglycemic effect in experimentally induced diabetic rats. DOI: http://dx.doi.org/10.3329/jdmc.v23i1.22687 J Dhaka Medical College, Vol. 23, No.1, April, 2014, Page 14-17

The Action of the Basic Trypsin Inhibitor, Trasylol, on Shock Resulting from Occlusion of the Superior Mesenteric Artery: Experimental Study

1981 ◽  
Vol 9 (1) ◽  
pp. 31-39 ◽  
Author(s):  
I Dadoukis ◽  
K Angouridakis ◽  
H Aletras
Keyword(s):  
Body Weight ◽  
Superior Mesenteric Artery ◽  
Intestinal Mucosa ◽  
Mesenteric Artery ◽  
Arterial Occlusion ◽  
Control Group ◽  
Experimental Animals ◽  
Group A ◽  
Group B ◽  
Group D

The action of the enzymic inhibitor Trasylol upon shock from occlusion of the superior mesenteric artery (SMA) in forty-six dogs, arranged in four groups, has been studied. In Group A of controls (thirteen dogs) an intestinal ischaemia of 31/2 hours duration was produced. After removal of the arterial occlusion, shock was produced in eleven dogs, which died within the first 24 hours. A frequent finding at autopsy was haemorrhagic infiltration of the intestinal mucosa and the occurrence of haemorrhagic contents in the intestinal lumen. Histologically, frequent findings were capillary distension and hyperaemia, perivascular haemorrhagic infiltration and superficial or total necrosis of the intestinal mucosa. In Group B (ten dogs), Group C (ten dogs) and Group D (thirteen dogs), the experimental arrangement was similar to that in Group A, except for Trasylol administration. An infusion of Trasylol, 30,000 units/kg body-weight intravenously 10 minutes before occlusion of the artery was given to the experimental animals of Group B, while a second infusion of 30,000 units/kg body-weight into the superior mesenteric artery or intravenously was given to the experimental animals of Group C and Group D, respectively, 10 minutes before the removal of arterial occlusion. The results in Group B were a little better in comparison with those of the controls, but the differences were not statistically significant. On the contrary, significant differences were seen with Group C and Group D. Shock was produced in a small number of experimental animals. Over 50% of the experimental animals survived. The intestinal alterations seen at autopsy and histologically were about the same as in the control group, but at a clearly lower frequency. It is concluded that the administration of enzymic inhibitors may eventually have a practical application in situations of re-establishment of mesenteric circulation after its acute interruption.

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