scholarly journals PENGARUH FAKTOR YANG BERHUBUNGAN DENGAN USIA TERHADAP KUALITAS HIDUP PASIEN EPILEPSI

2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Andre Dharmawan Wijono

Pendahuluan: Epilepsi merupakan penyakit neurologis yang mempengaruhi kualitas hidup penderitanya. Hanya ada sedikit penelitian tentang kualitas hidup pasien epilepsi di Indonesia. Tujuan: Melihat hubungan antara usia, usia saat onset pertama muncul, dan durasi epilepsi terhadap kualitas hidup pasien epilepsi. Metode: Penelitian cross-sectional ini dilakukan di Departemen Neurologi, Rumah Sakit Bethesda, Yogyakarta, Indonesia pada November 2017 sampai Februari 2018. Pasien epilepsi yang berusia ≥ 18 tahun diikutkan dalam penelitian ini. Kualitas hidup diukur menggunakan instrument Short form 8 (SF-8). Hasil: Terkumpul 27 pasien yang memenuhi kriteria inklusi. Pasien dengan usia ≥ 60 tahun secara signifikan mengalami penurunan kualitas hidup dalam beberapa aspek, yaitu: physical functioning (42.44±8.243), general health (40.04±7.641), role emotional (39.60±7.638), mental health (43.50±10.347), dan mental component score (42.04±10.282). Pasien dengan usia saat onset pertama muncul ≥ 55 tahun secara signifikan memiliki role emotional (40.54±7.245) dan mental component score (42.98±10.155) yang lebih rendah. Durasi epilepsi tidak memiliki hubungan yang signifikan terhadap kualitas hidup pasien epilepsi. Kesimpulan: Penelitian ini menunjukkan bahwa usia dan usia saat onset epilepsi pertama muncul berhubungan dengan kualitas hidup pasien epilepsi.   Kata kunci: Epilepsi, faktor risiko yang berhubungan dengan usia, kualitas hidup, SF-8.

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 1307-1307 ◽  
Author(s):  
John B Porter ◽  
Donald Bowden ◽  
Arnold Ganser ◽  
Gabor Domokos ◽  
Adam Gater ◽  
...  

Abstract Introduction: Iron chelation therapy (ICT) is essential in removing excess iron deposited in body organs, ultimately preventing organ failure and extending the lives of patients (pts) with transfusion-dependent hematological disorders such as β-thalassemia and myelodysplastic syndromes (MDS). As a life-long treatment, traditional ICT (deferoxamine, Desferal®, DFO) is based on a burdensome regimen (subcutaneous delivery 5–7 times a week) that has been shown to negatively impact on pts’ health-related quality of life (HRQoL). The oral chelator deferasirox (Exjade®) is less burdensome to pts offering 24-hour ICT, 7 days a week. Methods: This substudy was part of a single arm, multicenter, 1-year open-label trial (the EPIC study) to investigate the efficacy/safety of deferasirox. The first 558 pts with a variety of hematological disorders were recruited. These pts came from sites in seven countries: Australia, Belgium, France, Germany, UK, Greece, and Italy. Treatment-naïve pts and those having previously received ICT (DFO or deferiprone [Ferriprox®] exclusively, or combined) participated (n=558). Pts were asked at baseline, week 4 and week 52 (end of study [EOS]) to complete the 36-item Short Form health survey (SF-36). The SF-36 is a self-administered questionnaire and measures eight HRQoL domains: physical functioning; role-physical; bodily pain; general health; vitality; social functioning; role-emotional; and mental health. Mean change in SF-36 domain scores were calculated for all pts who had completed data at baseline and week 4, as well all those with completed data at baseline and EOS. All domains are scored so that higher scores indicate a better QoL. Results: Overall, the mean age of the 558 pts (274 β-thalassemia, 168 MDS, 50 sickle cell disease and 66 other anemias) recruited to take part in this substudy was 40.8 years (SD=22.58); 51.5% of patients (n=289) were male and 48.5% (n=272) were female. Within this sample, 337 pts aged ≥16 years completed the SF-36 at baseline, 322 at week 4 and 277 at EOS. Mean domain scores for pts at baseline, week 4 and EOS are presented in Table 1. With the exception of role-emotional (mean=0.78, SD=40.56), mean change in SF-36 domain scores significantly improved (P<0.05) for all domains between baseline and week 4: physical functioning (mean=2.42, SD=17.44); role-physical (mean=5.67, SD=41.70); bodily pain (mean=5.96, SD=24.15); general health (mean=0.33, SD=14.44); vitality (mean=2.54, SD=15.93); social functioning (mean=2.51, SD=23.38); mental health (mean=1.98, SD=14.71). At EOS, mean change in SF-36 domain scores improved for all domains with the exception of social functioning, role-emotional and mental health. However, unlike results at week 4, none of the mean change domain scores at EOS reached statistical significance, possibly due to sample size decrease between week 4 and EOS. Table 1. SF-36 domain scores at baseline, week 4 and EOS in pts aged 3 16 years and treated with deferasirox SF-36 domains Baseline mean (SD) Week 4 mean (SD) End of study mean (SD) Physical functioning 66.32 (25.98)
 n=336 69.70 (25.98)
 n=317 71.67 (26.95)
 n=275 Role-physical 54.33 (42.43) n=331 61.03 (42.69) n=315 62.38 (41.71) n=270 Bodily pain 65.80 (26.89)
 n=336 74.67 (26.16)
 n=322 73.11 (27.20)
 n=276 General health 46.62 (21.15)
 n=330 48.01 (22.32)
 n=311 48.42 (22.19)
 n=269 Vitality 51.12 (21.28)
 n=328 54.57 (22.06)
 n=316 55.80 (23.06)
 n=272 Social functioning 71.73 (25.74)
 n=336 74.77 (23.72)
 n=321 73.05 (24.71)
 n=276 Role-emotional 68.05 (40.92)
 n=326 69.60 (41.60)
 n=313 69.81 (40.44)
 n=270 Mental health 67.04 (19.85)
 n=328 70.40 (19.73)
 n=316 67.85 (20.19)
 n=272 Conclusions: Since mean change scores were often of the magnitude of 3 to 5 units for role-physical and bodily pain, these results indicate clinically meaningful improvement for pts with hematological disorders receiving deferasirox.


2014 ◽  
Vol 170 (6) ◽  
pp. 873-884 ◽  
Author(s):  
Line Pickering ◽  
Poul Jennum ◽  
Steen Gammeltoft ◽  
Lars Poulsgaard ◽  
Ulla Feldt-Rasmussen ◽  
...  

ObjectiveTo assess the influence of craniopharyngioma or consequent surgery on melatonin secretion, and the association with fatigue, sleepiness, sleep pattern and sleep quality.DesignCross-sectional study.MethodsA total of 15 craniopharyngioma patients were individually matched to healthy controls. In this study, 24-h salivary melatonin and cortisol were measured. Sleep–wake patterns were characterised by actigraphy and sleep diaries recorded for 2 weeks. Sleepiness, fatigue, sleep quality and general health were assessed by Multidimensional Fatigue Inventory, Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale and Short-Form 36.ResultsPatients had increased mental fatigue, daytime dysfunction, sleep latency and lower general health (all,P≤0.05), and they tended to have increased daytime sleepiness, general fatigue and impaired sleep quality compared with controls. The degree of hypothalamic injury was associated with an increased BMI and lower mental health (P=0.01). High BMI was associated with increased daytime sleepiness, daytime dysfunction, mental fatigue and lower mental health (all,P≤0.01). Low midnight melatonin was associated with reduced sleep time and efficiency (P≤0.03) and a tendency for increased sleepiness, impaired sleep quality and physical health. Midnight melatonin remained independently related to sleep time after adjustment for cortisol. Three different patterns of melatonin profiles were observed; normal (n=6), absent midnight peak (n=6) and phase-shifted peak (n=2). Only patients with absent midnight peak had impaired sleep quality, increased daytime sleepiness and general and mental fatigue.ConclusionCraniopharyngioma patients present with changes in circadian pattern and daytime symptoms, which may be due to the influence of the craniopharyngioma or its treatment on the hypothalamic circadian and sleep regulatory nuclei.


Author(s):  
Alfonso Urzúa ◽  
Alejandra Caqueo-Urízar ◽  
Diego Henríquez ◽  
David R. Williams

There is not much evidence on the effects of south–south migration and its consequences on physical and mental health. Our objective was to examine the mediating role of Acculturative Stress in the association between ethnic discrimination and racial discrimination with physical and mental health. This research is a non-experimental, analytical, cross-sectional study. A total of 976 adult Colombian migrants living in Chile were interviewed. We used the Everyday Discrimination Scale, the acculturative stress scale, and the Medical Outcomes Study Short Form (SF-12) for health status; we found that racial and ethnic discrimination had a negative effect on physical and mental health. In the simultaneous presence of both types of discrimination, racial discrimination was completely absorbed by ethnic discrimination, the latter becoming a total mediator of the effect of racial discrimination on mental and physical health. Our findings are consistent with the literature, which suggests that there are various types of discrimination which, individually or in their intersectionality, can have negative effects on health.


2021 ◽  
Vol 20 (3) ◽  
pp. 1-32
Author(s):  
Reyna Jazmín Martínez Arriaga ◽  
Leivy Patricia González Ramírez ◽  
Nancy Evelyn Navarro Ruiz ◽  
José María De la Roca -Chiapas ◽  
Oscar Ulises Reynoso González

Introducción: El personal de enfermería es uno de los grupos más afectados por la actual pandemia por COVID-19. Se han reportado problemas de salud mental en esta población, sin embargo, también es importante estudiar la resiliencia, para identificar sus fortalezas. El objetivo de este estudio fue estudiar la resiliencia en enfermeros mexicanos y los factores sociodemográficos y de salud mental asociados a ella. Se llevó a cabo un estudio transversal.Método: Se envió vía online un cuestionario sociodemográfico y relacionado a COVID-19, así como el Inventario de Resiliencia y el Cuestionario General de Salud-28. Se incluyeron 556 enfermeros, la mayoría fueron mujeres (80%), solteras (60.8%) y con edades entre 26-35 años (38.3%).Resultados: Se encontraron niveles bajos de resiliencia en los enfermeros más jóvenes (p<0.001, ɳ2=0.05), solteros (p<0.001, ɳ2=0.02) y con menor nivel educativo (p=0.001, ɳ2=0.02). Los predictores de resiliencia fueron la búsqueda de información sobre salud mental (β =-0.152, p <0.001), nivel educativo más alto (β = 0.142, p<0.001), niveles bajos de depresión (β=-0.307, p<0.001) y bajos niveles de disfunción social (β =-0.261, p<0.001).Conclusión: Estos hallazgos permiten identificar los factores asociados a la resiliencia en los enfermeros y cómo estos juegan un rol muy importante en su salud mental. Asimismo, estos datos permiten la identificación de grupos con mayor riesgo psicosocial, con la finalidad de guiar estrategias en salud mental orientadas a aumentar la resiliencia. Introduction: Nursing personnel are one of the groups which have been most affected by the current COVID-19 pandemic. Although mental health problems have been reported in this population, it is important to study resilience, in order to identify its strengths. The purpose was to study resilience in Mexican nurses and the mental health and sociodemographic factors associated with it. A cross-sectional study was used. Method: A sociodemographic and COVID-19 related questionnaire, the Resilience Inventory and the General Health Questionnaire-28, was sent via online. 556 nurses were included, the majority were women (80%), single (60.8%), aged between 26-35 years (38.3%). Results: Lower resilience was found among nurses who were younger (p<0.001, ɳ2=0.05), single (p<0.001, ɳ2=0.02) and with lower levels of education (p=0.001, ɳ2=0.02). Predictors of resilience included the search for mental health information (β =-0.152, p <0.001), higher education (β = 0.142, p<0.001), low levels of depression (β=-0.307, p<0.001) and low levels of social dysfunction (β =-0.261, p<0.001). Conclusion: This findings allowed to identify the factors which are associated with resilience among nurses and how this plays an important role in their mental. Likewise, this data allows for the identification of high psychosocial risk groups, to better guide mental health strategies aimed at increasing resilience. Resumo:Introdução:O pessoal de enfermagem é um dos grupos mais afetados pela atual pandemia de COVID-19. Problemas de saúde mental têm sido relatados nessa população, porém também é importante estudar a resiliência, para identificar seus pontos fortes. O objetivo deste estudo foi estudar a resiliência em enfermeiras mexicanas e os fatores sociodemográficos e de saúde mental a ela associados. Foi realizado um estudo transversal.Método:Um questionário sociodemográfico relacionado ao COVID-19 foi enviado online, assim como o Resilience Inventory e o General Health Questionnaire-28. Foram incluídos 556 enfermeiros, a maioria mulheres (80%), solteiros (60,8%) e com idade entre 26-35 anos (38,3%).Resultados:Baixos níveis de resiliência foram encontrados nos enfermeiros mais jovens (p <0,001, ɳ2 = 0,05), solteiros (p <0,001, ɳ2 = 0,02) e com menor escolaridade (p = 0,001, ɳ2 = 0,02). Os preditores de resiliência foram a busca por informações sobre saúde mental (β = -0,152, p <0,001), maior escolaridade (β = 0,142, p <0,001), baixos níveis de depressão (β = -0,307, p <0,001 ) e baixos níveis de disfunção social (β = -0,261, p <0,001).Conclusão:Esses achados permitem identificar os fatores associados à resiliência em enfermeiros e como eles desempenham um papel muito importante em sua saúde mental. Da mesma forma, esses dados permitem identificar grupos de maior risco psicossocial, a fim de nortear estratégias de saúde mental que visem aumentar a resiliência.


2014 ◽  
Vol 24 (4) ◽  
pp. 794-799
Author(s):  
Gabriela A. Caixeta ◽  
Emma E. C. Castro ◽  
Agnaldo L. Silva-Filho ◽  
Fernando M. Reis ◽  
José R. Cunha-Melo ◽  
...  

ObjectiveThe objective of this study was to compare the quality of life (QOL) and mental health (MH) of women surviving at least 2 years after treatment for invasive carcinoma of the cervix by radical hysterectomy (RH), chemotherapy and/or radiotherapy, or by surgery followed by adjuvant therapy (RH + chemotherapy and/or radiotherapy). The QOL/MH of a control group of women with no history of malignancy was also assessed for comparison with the treated groups.MethodsThe levels of QOL and MH were assessed in 114 Brazilian women (57 patients with an average of 4 years since treatment completion and 57 control subjects). The 36-item Medical Outcomes Study Short-Form Health Survey, the State-Trait Anxiety Inventory, the 12-item General Health Questionnaire, the Life Events Inventory, and a general survey for the assessment of sociodemographic data were applied to each participant of the study.ResultsNo differences were noted among the 3 treatment groups or between these and the control group concerning the levels of QOL (either physical or MH aspects), anxiety, general health, or life events. However, lower levels of anxiety were detected in cancer survivors when compared with the control group (P = 0.035).ConclusionsAfter at least 2 years, the QOL and the MH of Brazilian women treated for invasive carcinoma of the cervix were similar to those of women without malignancy and were not affected by the modality of treatment.


2020 ◽  
Vol 19 (4) ◽  
pp. 291-300
Author(s):  
Zeinab Alizadeh ◽  
Hamidreza Roohafza ◽  
Awat Feizi ◽  
Nizal Sarrafzadegan

Purpose This study aimed to examine the association of shift work with depression and anxiety in a large sample of formal and contractual employees of a mill steel company, Isfahan, Iran. Design/methodology/approach This cross-sectional study was performed in 2014 among 3,060 formal and contractual employees of a mill steel company Isfahan, Iran, randomly selected from 16,000 people. Data gathering was done by some validated Iranian version of self-administered questionnaires including, International Physical Activity – Short Form, Effort–Reward Imbalance, Hospital Anxiety and Depression Scale. Logistic regression was used as the main statistical method. Findings The results showed individuals in the rotating shift compared with day shift had a higher risk of depression (OR: 1.43; 95% CI: 1.12–1.84). Whereas after adjustment for various confounders, this relationship was not significant (OR: 1.19; 95% CI: 0.81–1.76). Anxiety was not associated with shift work, both in crude and adjusted models (OR: 1.08; 95% CI: 0.81–1.44) and (OR: 0.90; 95% CI: 0.67–1.19), respectively. Research limitations/implications Owing to the cross-sectional design of this study, cause–effect relationships could not be inferred from our findings. All the data used in the present analysis were collected by self-administered questionnaires. Practical implications Although our findings did not show significant association between shift work and mental health, further studies are suggested for obtaining informative data worldwide in this regard among workforce particularly among industrial employees. Originality/value Few studies have addressed the effects of shift work on mental health among industrial employees worldwide, and there is no study in developing countries.


Medicina ◽  
2020 ◽  
Vol 56 (12) ◽  
pp. 647
Author(s):  
Natasa Todorovic ◽  
Milutin Vracevic ◽  
Nina Rajovic ◽  
Vedrana Pavlovic ◽  
Petar Madzarevic ◽  
...  

Background and objectives: The COVID-19 pandemic has had an unprecedented reliance on informal caregivers as one of the pillars of healthcare systems. The aim of this study was to assess the quality of life of informal caregivers during the COVID-19 epidemic in Serbia. Materials and Methods: A cross-sectional study was conducted among informal caregivers during the COVID-19 epidemic in Serbia. Physical and mental quality of life was measured by the 36-Item Short-Form Health Survey. Additional data included sociodemographic characteristics, caregiver and care recipient characteristics, and COVID-19 related concerns. The qualitative component was performed using focus groups and individual in-depth interviews. Results: Out of 112 informal caregivers enrolled, most were female (80%), and the average age was 51.1 ± 12.3 years. The majority was delivering care to one person, who was a family member, on a daily basis (86.4%, 92%, and 91.1%, respectively). In multiple regression models, significant predictors of caregivers’ physical health were delivering care to a family member and a higher level of care complexity, while significant predictors of caregivers’ mental health were a higher level of care complexity and increased concerns about self-health and the health of the person being cared for due to the COVID-19 epidemic. Conclusions: Informal caregivers are experiencing negative physical and mental health outcomes during the COVID-19 epidemic in Serbia.


2020 ◽  
Vol 9 (11) ◽  
pp. 3708
Author(s):  
Stefanie Jung ◽  
Jonas Kneer ◽  
Tillmann H. C. Krüger

Preliminary data indicates that the Coronavirus SARS-CoV-2 disease (COVID-19) pandemic may have a substantial impact on mental health and well-being. We assessed mental health in response to the lockdown in Germany between 1 April 2020 and 15 April 2020 using a cross-sectional online survey (n = 3545) with a mixed-methods approach. We found increased levels of psychosocial distress (Patient Health Questionnaire (PHQ) stress module), anxiety, depressive symptoms (PHQ-4), irritability, and a decrease in overall well-being (WHO-Five Well-Being Index (WHO-5)), sense of coherence (Short Form of the Sense of Coherence Scale (SOC-L9)), sexual contentment, and sleep quality. The four-week-prevalence of interpersonal violence was yet at 5% and included verbal, physical, and sexual violence. Participants reported finding comfort in family, friends, conversation, exercise, and activity. Findings are also in line with research showing that women seem to have more trouble coping with the pandemic and lockdown measures. Our observations demonstrate that the COVID-19 pandemic and related measures lead to a mental health burden even in a highly developed Western country and should, therefore, be taken seriously. The findings for interpersonal violence are alarming. Thus, we should sharpen our focus on the matter and activate and enhance supporting systems to help protect those affected.


Spine ◽  
2020 ◽  
Vol 45 (3) ◽  
pp. 201-207
Author(s):  
Srikanth N. Divi ◽  
Dhruv K.C. Goyal ◽  
John J. Mangan ◽  
Matthew S. Galetta ◽  
Kristen J. Nicholson ◽  
...  

2020 ◽  
Vol 32 (6-7) ◽  
pp. 320-327 ◽  
Author(s):  
Mila Nu Nu Htay ◽  
Swe Swe Latt ◽  
Khine Sandar Maung ◽  
Wai Wai Myint ◽  
Soe Moe

International migration has become a global phenomenon bringing with it complex and interrelated issues related to the physical and mental well-being of the people involved. This study investigated the mental well-being and factors associated with mental health among Myanmar migrant workers (MMW) in Malaysia. The cross-sectional study was conducted in Penang, Malaysia by using the WHO-5 Well-Being Index Scale (WHO-5) and the Mental Health subscale of 36 items in the Short Form Health Survey (SF-36). Among 192 migrant workers who were understudied, 79.2% had poor mental well-being according to the WHO-5 scale. The duration of stay in Malaysia and without receiving financial aid from their employers despite having a physical illness were significantly associated with poor mental well-being. Mental health support groups should target migrant workers for mental health education and find ways to provide assistance for them. Furthermore, premigration training should be delivered at the country of origin that also provides information on the availability of mental health support in the host country.


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