Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners

Background: The aim of this study was to determine the effect of purslane supplementation on oxidative stress, inflammation and muscle damage biomarkers after completing high-intensity interval exercise (HIIE). Methods: Nine healthy female runners completed a HIIE treadmill protocol comprising 1 min at 100% of the peak treadmill velocity attained in a preliminary exhaustive incremental treadmill test, interspersed by 1 min of passive recovery, until they had run for 2.5 km. Athletes repeated this test following 10 days of supplementation with 1000 mg per day of purslane. Results: At baseline (i.e., absence of purslane supplementation) the HIIE protocol increased 9-HODE (p < 0.001), 13-HODE (p < 0.001), IL-17 (p < 0.001), TNF-α (p < 0.001), and LDH (p < 0.001). After purslane consumption, resting 9-HODE, 13-HODE, IL-17, TNF-α, and LDH were lowered (p < 0.001) and IL-10 was increased (p < 0.001) compared to before purslane supplementation. After purslane consumption and following the HIIE protocol, the responses of these biomarkers were lower compared to baseline (p < 0.001). Conclusion: Ten days of purslane supplementation blunted the perturbation to biomarkers of oxidative stress, inflammation and muscle damage in female runners completing a HIIE protocol.

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Effects of uphill high-intensity interval exercise on muscle damage and exercise performance during recovery

The Journal of Sports Medicine and Physical Fitness ◽

10.23736/s0022-4707.20.11621-9 ◽

2021 ◽

Vol 61 (9) ◽

Author(s):

Rony FARES ◽

Miguel Á. RODRÍGUEZ ◽

Kaissar KAIROUZ ◽

Germán VICENTE-RODRÍGUEZ ◽

Hugo OLMEDILLAS

Keyword(s):

Muscle Damage ◽

Exercise Performance ◽

High Intensity ◽

Interval Exercise ◽

High Intensity Interval

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Effects of high-intensity interval exercise under hyperoxia on HSP27 and oxidative stress responses

Respiratory Physiology & Neurobiology ◽

10.1016/j.resp.2020.103544 ◽

2021 ◽

Vol 283 ◽

pp. 103544

Author(s):

Michihiro Kon ◽

Kosuke Taniguchi ◽

Yoshiko Ebi ◽

Kohei Nakagaki

Keyword(s):

Oxidative Stress ◽

Stress Responses ◽

High Intensity ◽

Interval Exercise ◽

High Intensity Interval ◽

Oxidative Stress Responses ◽

And Oxidative Stress

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Effect of 1-week Calendula officinalis consumption before high-intensity interval exercise on some delayed onset muscle soreness (DOMS) elements in male rowers

Comparative Exercise Physiology ◽

10.3920/cep200087 ◽

2021 ◽

pp. 1-8

Author(s):

B. Mohammadi ◽

L. Anoosheh ◽

S. Rahmati-Ahmadabad

Keyword(s):

High Intensity ◽

Muscle Soreness ◽

Pain Perception ◽

Delayed Onset Muscle Soreness ◽

Calendula Officinalis ◽

Interval Exercise ◽

Delayed Onset ◽

Tnf Α ◽

High Intensity Interval ◽

Experimental Group

Previous studies showed that some medicinal herbs can prevent delayed onset muscle soreness (DOMS). The present study investigates the effect of Calendula officinalis supplementation on DOMS elements on male rowers. Thirty healthy adult male rowers were randomly chosen and equally divided into experimental and control groups. Blood samples, Sargent jumps (SJ), and pain perception tests were measured at the starting point. The experimental group consumed (twice a day, 200 μl each time) C. officinalis extract for a week while the control group received a placebo. After consuming the supplementations for a week, the second samples and tests were taken. All the athletes participated in the high-intensity interval exercise (HIIE – a muscle soreness protocol). Third, fourth, and fifth samples/tests were executed immediately, 24 and 48 h after HIIE. Statistical analysis was conducted and P≤0.05 was considered as the significant level. The results showed that HIIE induced a significant increase in the serum tumour necrosis factor-alpha (TNF-α) and creatine kinase-MB (CK-MB) values as well as the pain perception in both groups. TNF-α and pain perception were significantly lower in the experimental group immediately, 24 and 48 h after HIIE. CK-MB activity was significantly decreased in the experimental group during next 24 and 48 h after HIIE. The muscle soreness protocol and its preceding supplementation had no significant effect on SJ. The present study suggests that the consumption of C. officinalis based on the present study dose and timespan may be effective to attenuate inflammation and pain induced by HIIE in male rowers and probably has no functional impact on muscle.

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Short-term high-intensity interval exercise training attenuates oxidative stress responses and improves antioxidant status in healthy humans

Food and Chemical Toxicology ◽

10.1016/j.fct.2013.05.046 ◽

2013 ◽

Vol 61 ◽

pp. 171-177 ◽

Cited By ~ 57

Author(s):

G.C. Bogdanis ◽

P. Stavrinou ◽

I.G. Fatouros ◽

A. Philippou ◽

A. Chatzinikolaou ◽

...

Keyword(s):

Oxidative Stress ◽

Exercise Training ◽

Stress Responses ◽

High Intensity ◽

Antioxidant Status ◽

Short Term ◽

Interval Exercise ◽

Healthy Humans ◽

High Intensity Interval ◽

Oxidative Stress Responses

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Effect of purslane seed supplementation on inflammatory cytokines, oxidative stress and muscle damage in response to high-intensity intermittent exercise in national athlete runners

Sport Sciences for Health ◽

10.1007/s11332-019-00572-y ◽

2019 ◽

Vol 16 (1) ◽

pp. 47-54

Author(s):

Mohammad Mehdi Zare ◽

Amine Ghram ◽

Ali Akbarnejad ◽

Rahman Soori ◽

Anis Charkhi Sahl Abad ◽

...

Keyword(s):

Oxidative Stress ◽

Muscle Damage ◽

Inflammatory Cytokines ◽

High Intensity ◽

Intermittent Exercise ◽

Purslane Seed

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Faculty Opinions recommendation of High intensity, interval exercise improves quality of life of patients with chronic heart failure: a randomized controlled trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718129195.793522541 ◽

2016 ◽

Author(s):

Jerome Fleg

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Randomized Controlled Trial ◽

Chronic Heart Failure ◽

High Intensity ◽

Controlled Trial ◽

Interval Exercise ◽

Randomized Controlled ◽

High Intensity Interval

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Faculty Opinions recommendation of High-intensity interval training beneficial effects on body mass, blood pressure, and oxidative stress in diet-induced obesity in ovariectomized mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726692682.793522525 ◽

2016 ◽

Author(s):

Jerome Fleg

Keyword(s):

Oxidative Stress ◽

Blood Pressure ◽

High Intensity ◽

Interval Training ◽

High Intensity Interval Training ◽

Beneficial Effects ◽

Diet Induced Obesity ◽

Ovariectomized Mice ◽

High Intensity Interval ◽

And Oxidative Stress

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Effects of L-citrulline supplementation on nitric oxide and antioxidant markers after high-intensity interval exercise in young men: a randomized controlled trial

British Journal Of Nutrition ◽

10.1017/s0007114521002178 ◽

2021 ◽

pp. 1-23

Author(s):

Kosar Valaei ◽

Javad Mehrabani ◽

Alexei Wong

Keyword(s):

Nitric Oxide ◽

High Intensity ◽

Controlled Trial ◽

Young Men ◽

No Production ◽

Double Blind ◽

Interval Exercise ◽

Damage Indices ◽

High Intensity Interval ◽

Antioxidant Markers

Abstract L-citrulline (L-Cit) is a nonessential amino acid that stimulates nitric oxide (NO) production and improves exercise performance by reducing muscle damage indices; however, the direct benefits of L-Cit on antioxidant markers are unclear. The aim of this study was to examine antioxidant responses to high-intensity interval exercise following acute L-Cit supplementation. Nine young men (21 ± 1 years) participated in a double-blind crossover study in which they received 12 g of L-Cit and placebo (PL) an hour prior to high-intensity interval exercise on two occasions, separated by a seven-day washout period. Blood samples were obtained before (PRE), immediately after (IP), 10 (10P), and 30 min after exercise (30P) from the cubital vein using standard procedures. Serum concentrations of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), and NO metabolites (NOx) were measured. The exercise protocol significantly elevated SOD (p = 0.01) and GPx (p = 0.048) from PRE to 10P in the L-Cit group with greater changes than the PL group. CAT concentrations increased IP (p = 0.014) and remained elevated at 10P (p = 0.03) and 30P (p = 0.015) in both the L-Cit and PL conditions. NOx concentrations increased IP (p = 0.05) in the L-Cit group with greater changes than PL group in PRE to IP, PRE to 10P, and PRE to 30P (p < 0.05). Our data indicate that L-Cit supplementation (single 12 g dose pre-exercise) induces improvements in antioxidant markers following a session of high-intensity interval exercise in young men.

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Influence of Carbohydrate Supplementation on Plasma Cytokine and Neutrophil Degranulation Responses to High Intensity Intermittent Exercise

International Journal of Sport Nutrition and Exercise Metabolism ◽

10.1123/ijsnem.12.2.145 ◽

2002 ◽

Vol 12 (2) ◽

pp. 145-156 ◽

Cited By ~ 41

Author(s):

Nicolette C. Bishop ◽

Michael Gleeson ◽

Ceri W. Nicholas ◽

Ajmol Ali

Keyword(s):

High Intensity ◽

Intermittent Exercise ◽

Plasma Concentrations ◽

Neutrophil Function ◽

Moderate Intensity ◽

Post Exercise ◽

Carbohydrate Supplementation ◽

Tnf Α ◽

Neutrophil Degranulation ◽

Factor Α

Ingesting carbohydrate (CHO) beverages during prolonged, continuous heavy exercise results in smaller changes in the plasma concentrations of several cytokines and attenuates a decline in neutrophil function. In contrast, ingesting CHO during prolonged intermittent exercise appears to have negligible influence on these responses, probably due to the overall moderate intensity of these intermittent exercise protocols. Therefore, we examined the effect of CHO ingestion on plasma interIeukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and lipopolysaccharide (LPS)-stimuIated neutrophil degranulation responses to high-intensity intermittent running. Six trained male soccer players performed 2 exercise trials, 7 days apart, in a randomized, counterbalanced design. On each occasion, they completed six 15-min periods of intermittent running consisting of maximal sprinting interspersed with less intense periods of running and walking. Subjects consumed either CHO or artificially sweetened placebo(PLA) beverages immediately before and at 15-min intervals during the exercise. At 30 min post-exercise, CHO versus PLA was associated with a higher plasma glucose concentration (p< .01), a lower plasma cortisol and IL-6 concentration (p < .02), and fewer numbers of circulating neutrophils (p < .05). Following the exercise, LPS-stimulated elastase release per neutrophil fell 31 % below baseline values on the PLA trial (p = .06) compared with 11% on the CHO trial (p = .30). Plasma TNF-α concentration increased following the exercise (main effect of time, p < .001) but was not affected by CHO. These data indicate that CHO ingestion attenuates changes in plasma IL-6 concentration, neutrophil trafficking, and LPS-stimulated neutrophil degranulation in response to intermittent exercise that involves bouts of very high intensity exercise.

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