The Role Of The Brazilian Churches As Therapeutic Communities To First Generation Brazilian Immigrants

2005 ◽  
Author(s):  
Manoel OLIVEIRA
Keyword(s):  
First Generation ◽  
Therapeutic Communities ◽  
Brazilian Immigrants

Rapid evaluation of FDG imaging alternatives using head-to-head comparisons of full ring and gamma camera based PET scanners –

2002 ◽  
Vol 41 (05) ◽  
pp. 208-213 ◽  
Author(s):  
L. M. Haslinghuis-Bajan ◽  
L. Hooft ◽  
A. van Lingen ◽  
M. van Tulder ◽  
W. Devillé ◽  
...  
Keyword(s):  
Methodological Quality ◽  
Gamma Camera ◽  
First Generation ◽  
Prospective Evaluation ◽  
First Approximation ◽  
Variable Head ◽  
Malignant Lesions ◽  
The Impact ◽  
Pet Scanners

SummaryAim: While FDG full ring PET (FRPET) has been gradually accepted in oncology, the role of the cheaper gamma camera based alternatives (GCPET) is less clear. Since technology is evolving rapidly, “tracker trials” would be most helpful to provide a first approximation of the relative merits of these alternatives. As difference in scanner sensitivity is the key variable, head-to-head comparison with FRPET is an attractive study design. This systematic review summarises such studies. Methods: Nine studies were identified until July 1, 2000. Two observers assessed the methodological quality (Cochrane criteria), and extracted data. Results: The studies comprised a variety of tumours and indications. The reported GC- and FRPET agreement for detection of malignant lesions ranged from 55 to 100%, but with methodological limitations (blinding, standardisation, limited patient spectrum). Mean lesion diameter was 2.9 cm (SD 1.8), with only about 20% <1.5 cm. The 3 studies with the highest quality reported concordances of 74-79%, for the studied lesion spectrum. Contrast at GCPET was lower than that of FRPET, contrast and detection agreement were positively related. Logistic regression analysis suggested that pre-test indicators might be used to predict FRPET-GCPET concordance. Conclusion: In spite of methodological limitations, “first generation” GCPET devices detected sufficient FRPET positive lesions to allow prospective evaluation in clinical situations where the impact of FRPET is not confined to detection of small lesions (<1.5 cm). The efficiency of head-to-head comparative studies would benefit from application in a clinically relevant patient spectrum, with proper blinding and standardisation of acquisition procedures.

THE ROLE OF POLYETHYLENIMINE IN ENHANCING PERFORMANCE OF GLUTAMATE BIOSENSORS

2018 ◽  
Vol 8 (3) ◽  
pp. 36-41
Author(s):  
Diep Do Thi Hong ◽  
Duong Le Phuoc ◽  
Hoai Nguyen Thi ◽  
Serra Pier Andrea ◽  
Rocchitta Gaia
Keyword(s):  
First Generation ◽  
Good Reproducibility ◽  
Complex Matrices ◽  
Long Term Stability ◽  
In Vitro Characterization ◽  
Glutamate Oxidase

Background: The first biosensor was constructed more than fifty years ago. It was composed of the biorecognition element and transducer. The first-generation enzyme biosensors play important role in monitoring neurotransmitter and determine small quantities of substances in complex matrices of the samples Glutamate is important biochemicals involved in energetic metabolism and neurotransmission. Therefore, biosensors requires the development a new approach exhibiting high sensibility, good reproducibility and longterm stability. The first-generation enzyme biosensors play important role in monitoring neurotransmitter and determine small quantities of substances in complex matrices of the samples. The aims of this work: To find out which concentration of polyethylenimine (PEI) exhibiting the most high sensibility, good reproducibility and long-term stability. Methods: We designed and developed glutamate biosensor using different concentration of PEI ranging from 0% to 5% at Day 1 and Day 8. Results: After Glutamate biosensors in-vitro characterization, several PEI concentrations, ranging from 0.5% to 1% seem to be the best in terms of VMAX, the KM; while PEI content ranging from 0.5% to 1% resulted stable, PEI 1% displayed an excellent stability. Conclusions: In the result, PEI 1% perfomed high sensibility, good stability and blocking interference. Furthermore, we expect to develop and characterize an implantable biosensor capable of detecting glutamate, glucose in vivo. Key words: Glutamate biosensors, PEi (Polyethylenimine) enhances glutamate oxidase, glutamate oxidase biosensors

scholarly journals Dynamical evolution of multiple-population globular clusters

2021 ◽  
Vol 502 (3) ◽  
pp. 4290-4304
Author(s):  
Enrico Vesperini ◽  
Jongsuk Hong ◽  
Mirek Giersz ◽  
Arkadiusz Hypki
Keyword(s):  
Structural Properties ◽  
Globular Clusters ◽  
First Generation ◽  
Radial Profile ◽  
Dynamical Evolution ◽  
Evolutionary Phase ◽  
Dynamical Parameters ◽  
Energy Equipartition

ABSTRACT We have carried out a set of Monte Carlo simulations to study a number of fundamental aspects of the dynamical evolution of multiple stellar populations in globular clusters with different initial masses, fractions of second generation (2G) stars, and structural properties. Our simulations explore and elucidate: (1) the role of early and long-term dynamical processes and stellar escape in the evolution of the fraction of 2G stars and the link between the evolution of the fraction of 2G stars and various dynamical parameters; (2) the link between the fraction of 2G stars inside the cluster and in the population of escaping stars during a cluster’s dynamical evolution; (3) the dynamics of the spatial mixing of the first-generation (1G) and 2G stars and the details of the structural properties of the two populations as they evolve toward mixing; (4) the implications of the initial differences between the spatial distribution of 1G and 2G stars for the evolution of the anisotropy in the velocity distribution and the expected radial profile of the 1G and 2G anisotropy for clusters at different stages of their dynamical history; and (5) the variation of the degree of energy equipartition of the 1G and the 2G populations as a function of the distance from the cluster’s centre and the cluster’s evolutionary phase.

scholarly journals Exploring Ethnic and Generational Differences in Gender Role Attitudes among Immigrant Populations in Britain: The Role of Neighborhood Ethnic Composition

2018 ◽  
Vol 53 (4) ◽  
pp. 1121-1147 ◽  
Author(s):  
Senhu Wang ◽  
Rory Coulter
Keyword(s):  
Gender Role ◽  
Cultural Values ◽  
Generational Differences ◽  
First Generation ◽  
Second Generation ◽  
Ethnic Disparities ◽  
Gender Role Attitudes ◽  
Ethnic Composition ◽  
Nationally Representative

Divergent gender role attitudes among ethnic groups in Britain are thought to contribute to ethnic disparities in many socio-economic domains. Using nationally representative data (2010–2011), we investigate how ethnic minority gender role attitudes vary across generations and with neighborhood ethnic composition. The results show that while Pakistanis, Bangladeshis, Indians, and Black Africans have more traditional attitudes than Black Caribbeans, the attitudes of the former groups are more traditional in the first than in the second generation. We also find that the gender role attitudes of Pakistanis, Bangladeshis, and Indians become more traditional as the local share of co-ethnic neighbors increases or the share of White British residents decreases. Importantly, these patterns are more pronounced for second-generation Pakistanis and Bangladeshis, whose gender role attitudes are more sensitive to variations in neighborhood ethnic composition than are those of the first generation. Taken together, these findings indicate that migration researchers must conceptualize and study how immigrants’ cultural values are heterogeneous, fluid, and dynamic characteristics that can vary spatially across host societies.

scholarly journals Disparities in Sleep Health among Adolescents: The Role of Sex, Age, and Migration

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Maria Jose Miguez ◽  
Diego Bueno ◽  
Caroline Perez
Keyword(s):  
Sleep Disturbances ◽  
First Generation ◽  
Sleep Problems ◽  
Cultural Backgrounds ◽  
Use Of Technology ◽  
Sleep Debt ◽  
Adjusted Logistic Regression ◽  
Cultural Ecological ◽  
And Migration

Background. Disparities in sleep disturbances have been described in adults; nevertheless, among adolescents, data have yielded conflicting results. Therefore, analyses of our cohort study of 500 urban, normally developed Hispanic adolescents (10–18 years), aim to determine if rates of sleep debt differ between: (a) male and female adolescents, (b) US-born Hispanics and first-generation immigrant ethnic counterparts, and (c) specific activities that these teens trade for sleep. Participants’ weekday and weekend sleep patterns, along with the reasons for sleeping less than the recommended hours were recorded. Standardized surveys were used to gather information regarding sociodemographics, migration, acculturation, and medical history. Using the criteria set forth by the National Sleep Foundation, analyses indicated that sleep deprivation is a pervasive problem, with 75% in the preadolescents and 45% of the late adolescents exhibiting sleep problems. Females slept on average at least one hour less per day than their male counterparts (7 vs. 8 hours). The sleep problems were rooted in several overlapping causes, including use of technology, video games, studying, and employment. Nevertheless, reasons for sleep loss differed by gender and by immigrant status. Multivariable adjusted logistic regression analyses showed that females, US-born teens, and preadolescents had higher odds of being sleep deprived. Pediatricians and sleep experts should be aware of gender-specific causes and responses of sleep problems. Cultural ecological frameworks need to be considered, and clearly indicate that findings may not generalize to youth from other cultural backgrounds.

scholarly journals AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients

2019 ◽  
Vol 8 (4) ◽  
pp. 367-377 ◽  
Author(s):  
Adrian F Daly ◽  
Liliya Rostomyan ◽  
Daniela Betea ◽  
Jean-François Bonneville ◽  
Chiara Villa ◽  
...  
Keyword(s):  
First Generation ◽  
Follicular Thyroid Carcinoma ◽  
Somatostatin Analogs ◽  
Hormonal Control ◽  
Interacting Protein ◽  
Aryl Hydrocarbon ◽  
Tumor Residue ◽  
Baseline Levels

Acromegaly is a rare disease due to chronic excess growth hormone (GH) and IGF-1. Aryl hydrocarbon receptor interacting protein (AIP) mutations are associated with an aggressive, inheritable form of acromegaly that responds poorly to SST2-specific somatostatin analogs (SSA). The role of pasireotide, an SSA with affinity for multiple SSTs, in patients with AIP mutations has not been reported. We studied two AIP mutation positive acromegaly patients with early-onset, invasive macroadenomas and inoperable residues after neurosurgery. Patient 1 came from a FIPA kindred and had uncontrolled GH/IGF-1 throughout 10 years of octreotide/lanreotide treatment. When switched to pasireotide LAR, he rapidly experienced hormonal control which was associated with marked regression of his tumor residue. Pasireotide LAR was stopped after >10 years due to low IGF-1 and he maintained hormonal control without tumor regrowth for >18 months off pasireotide LAR. Patient 2 had a pituitary adenoma diagnosed when aged 17 that was not cured by surgery. Chronic pasireotide LAR therapy produced hormonal control and marked tumor shrinkage but control was lost when switched to octreotide. Tumor immunohistochemistry showed absent AIP and SST2 staining and positive SST5. Her AIP mutation positive sister developed a 2.5 cm follicular thyroid carcinoma aged 21 with tumoral loss of heterozygosity at the AIP locus and absent AIP staining. Patients 1 and 2 required multi-modal therapy to control diabetes. On stopping pasireotide LAR after >10 years of treatment, Patient 1’s glucose metabolism returned to baseline levels. Long-term pasireotide LAR therapy can be beneficial in some AIP mutation positive acromegaly patients that are resistant to first-generation SSA.

scholarly journals The Impact of Owner Gender in Family Businesses in Indonesia Liliana Dewi, Kazia Laturette, and I Gusti Bagus Yos

2021 ◽  
Author(s):  
Liliana Dewi ◽  
Kazia Laturette ◽  
I Gusti Bagus Yosia Wiryakusuma
Keyword(s):  
Family Business ◽  
First Generation ◽  
Future Generations ◽  
Early Age ◽  
Next Generation ◽  
Female Leaders ◽  
The Family ◽  
Long Time ◽  
The Impact

There are differences in the way people perceive the role of women and men in business. The purpose of this study was to analyze the influence of male or female leaders on two business families in Indonesia. The success of the family company cannot be separated from the role of the first generation in trusting future generations to continue their family business. A qualitative approach was used, where the data were collected through interviews with two family companies with different generations of successors. One family company has a female successor generation and another family company has a male successor. The findings showed that the first generation trusted from an early age and involved the second generation in the family business, whether their children were girls or boys. In fact, all succeeded in taking over the baton of leadership. An interesting finding is that even though the next generation is female and handles welding, which is more commonly done by men, thanks to the trust given by their parents, this next generation would be more masculine in order to gain legitimacy from employees who have worked for a long time in the company. This is as good as the next generation of men in other family companies. Keywords: family business, gender, first-generation roles, succession of success

Sign in / Sign up

Export Citation Format

Share Document