scholarly journals NEW APPROACH FOR TREATMENT OF CUTANEOUS LEISHNIANIASIS BY MAN NITOL

2021 ◽  
Vol 22 (1) ◽  
pp. 113-129
Author(s):  
Mohammed A.Kadir ◽  
Nidham A. Jaleel ◽  
Karim A. K. Al-Zaidaw

The present study was carried outinHaWija District and surrounding villages. Three villages were chosen (Al-Kadhemia,Sader A1-Naher, A1-Ameniea). The high incidence rate of cutaneous leishmaniasis was during the Winter months (December 1996 to March 1997). The total positive cases were 227 ( 111 males and 116 females). The highest incidence rate was among childeren fiom 1-10 years old. Intralesional mannitol solution was shown to be more effective ( 93.89% ) than Hypertonic Sodium Chloride 7% (HSCS) ( 87.50% ) but almost identical to pentostam ( 96.20% ). Most of lesions were cured in first and second injection, in all three treated groups but few of them needed the third injection. In all three treated groups, the scar was absent or minimum afier healing. None of the control lesions cured-within 6-8 Weeks. It is concluded that 20% rnannitol is aneffective local method of treatment for acute cutaneous leishmaniasis. The efficacy of 20% of mannitol is identical to pentostam and greater than 7% “ HSCS”. i

2021 ◽  
Vol 50 (4) ◽  
pp. 38-42
Author(s):  
R. G. Gataulina

The study reports on the analysis of the anamnestic data of2044 women with reproductive disorders who underwent operative interventions for tumors and tumorlike masses of the ovaries during the period of 1989-1999 in the Research Center of Obstetrics, Gynecology and Perinatology of the Russian Academy of Medical Sciences. A high incidence rate о f complicated anamnesis and the coexisting somatic and extragenital diseases was revealed. The data are presented concerning the status of menstrual and reproductive function of the patients examined.


2021 ◽  
Author(s):  
Junjun Shen ◽  
Tao Yang ◽  
Yiping Tang ◽  
Tianyi Guo ◽  
Ting Guo ◽  
...  

Nasopharyngeal carcinoma has a notably high incidence rate in Southern China, Southeast Asia, North Africa, Middle East, and the Arctic. δ-tocotrienol is abundant in cereal and has some health benefits....


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
V Bourdin ◽  
L Manitchoko ◽  
P Azouvi ◽  
R Hellmann ◽  
L Josseran

Abstract Background Traumatic brain injury (TBI) is a major public health issue, with a significant socio-economic burden. In France, very little is known about TBI epidemiology, and the TBI population is mainly described via studies carried out on the most severe patients. A large number of studies showed that a significant proportion of patients suffer from long-term disability after mild TBI (mTBI). This Post-Concussive Syndrome (PCS) remains poorly known by health professionals. Identifying early prognostic factors for the development of PCS is therefore essential, since it can ensure widespread clinical and economic benefits. This work aims at providing an updated description of the incidence of mild TBI (mTBI) based on data from Emergency Departments (ED) in the Ile-de-France (IDF) region (Paris area). Methods We estimated the mTBI incidence, using mainly data from the OSCOUR (Organisation de la Surveillance Coordonnée des Urgences) database from 01/01/2011 to 31/12/2015. The OSCOUR Network data collection methodology is based on the registration of all patients visiting the emergency services (ED) of participating hospitals. An extrapolation of the proportion of TBI patients visiting an OSCOUR ED to all ED of the IDF allowed us to compute a mTBI Annual Incidence Rate (AIR) in IDF. Results Between 2011 and 2015, 95,910 mTBI patients visited the OSCOUR ED in IDF, and the AIR was estimated at 292.4/100,000 inhabitants (when reported to the French population scale: a total of 196,000 mTBI are supposed to happen each year). Conclusions The surprisingly high incidence rate of mTBI observed in this study requires an evaluation of public health measures to prevent these injuries and reduce their consequences. New screening procedures should be implemented to point out the patients at risk for complications and PCS. Alongside the care aspect, prevention should be developed to reduce the incidence of TBIs, and prevention policies should be assessed by reiterating our evaluation. Key messages Between 2011 and 2015, 95,910 mTBI patients visited the OSCOUR Emergency Departments in Ile de France, and the annual incident rate was estimated at 292.4/100,000 inhabitants. The mTBI high incidence rate requires an evaluation of public health measures to prevent these injuries and reduce their consequences, but also the implementation of new screening procedures.


2011 ◽  
Vol 34 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Behnam Keshavarzi ◽  
Farid Moore ◽  
Ali Najmeddin ◽  
Farah Rahmani ◽  
Ahad Malekzadeh

2018 ◽  
Vol 35 (2) ◽  
pp. 32-36
Author(s):  
Ya. Yu. Illek ◽  
M. L. Vyaznikova ◽  
N. P. Leushina ◽  
I. Yu. Mischenko ◽  
L. L. Ryseva ◽  
...  

Aim. To determine the peculiarities of distributing antigens of major histocompatibility complex in children with atopic dermatitis and children with bronchial asthma. Materials and methods. Serologic typing of HLA class I-complex antigens and molecular typing of HLA class II-complex antigens was fulfilled in 52 children (age range 5 to 14 years) with disseminated moderate and severe atopic dermatitis and 122 children (age range 5 to 14 years) with moderate and severe atopic bronchial asthma. Results. Among children with atopic dermatitis, there was found high incidence rate of HLA-complex antigens B15, B16, B17, DRB1*13 and DQB1*0602-8, presentation of which was associated with elevation of relative risk for the development of disease by 3.3–8.4 times. In children with atopic bronchial asthma, the observed high incidence rate of HLA-complex antigens A26, B18 and DRB1*17 was associated with rise of relative risk for the development of disease by 3.0–9.1 times.


2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Nisa Kamila

AbstrakSelama tahun 2010-2014, Kota Semarang selalu termasuk dalam peringkat tiga besar Incidence Rate Deman Berdarah Dengue (DBD) di Provinsi Jawa Tengah. Penelitian ini bertujuan menganalisis pembiayaan program pemberantasan DBD bersumber pemerintah pada tahun 2013-2015 dan kesenjangan sumberdaya. Pendekatan akun biaya kesehatan (health account) digunakan untuk menelusuri pembiayaan menurut sumber, fungsi, dan penyedia layanan. Hasil studi menunjukkan bahwa total belanja program DBD bersumber APBD tahun 2013 adalah Rp. 4.018.927.020,- meningkat sebesar 101% pada tahun 2014 dan meningkat sebesar 218% pada tahun 2015. Belanja terbesar pada program pemberantasan DBD adalah untuk kegiatan surveilans epidemiologi dan pengendalian penyakit menular. Tidak terdapat kesenjangan antara ketersediaan sumber daya (berdasarkan belanja kesehatan program pemberantasan DBD) dengan kebutuhan program (berdasarkan perhitungan kebutuhan metode SPM). Disarankan agar perencanaan program lebih berfokus pada kegiatan promotif dan preventif. AbstractIn 2010–2014, Semarang was involved as the big three city with high incidence rate of dengue in Central Java province. This study aimed to analyze the financing by the local government for Dengue preventive program in 2013-2015, as well as the resources gap.The health account approach was used to analyze spending by source, function, and provider. Total local government spending for dengue in 2013 were IDR 4.018.927.020,- increased by 101% in 2014 and increased by 218% in 2015. The largest expenditure for Dengue Preventive program is epidemiological surveillance and infectious disease control. There was no gap between available resources and requires program according to SPM. The study suggested to improve planning by focusing on the direct activities such as promotive and preventive.


2019 ◽  
Author(s):  
Mohammad Alhawarat ◽  
Yousef Khader ◽  
Bassam Shadfan ◽  
Nasser Kaplan ◽  
Ibrahim Iblan

BACKGROUND Cutaneous leishmaniasis (CL) is endemic in the Middle East, with countries such as Syria reporting high incidence rates. OBJECTIVE This study aimed to assess the trends in the incidence of cutaneous leishmaniasis (CL) in Jordan from 2010 to 2016. METHODS This retrospective study included all cases of CL that had been reported to the Leishmaniasis Surveillance System in the Department of Communicable Diseases at the Jordan Ministry of Health during the period from 2010 to 2016. A total of 1243 cases were reported and met the case definition. RESULTS A total of 1243 cases (60.65% [754/1243] males and 39.34% [489/1243] females) were diagnosed during the study period. Of this sample, 233 patients (19.13%) were aged <5 years old, 451 (37.03%) were aged between 5-14 years old, 190 (15.60%) were aged between 15-24 years old, and 344 (28.24%) were aged ≥25 years old. Of those, 646 (51.97%) were Jordanians and 559 (44.97%) were Syrians. The average annual incidence rate of 1.70 per 100,000 people between 2010 and 2013 increased to 3.00 per 100,000 people in the years 2014 to 2016. There was no difference in incidence rates between Jordanians and Syrian refugees between 2010 and 2012. After 2012, the incidence rate increased significantly among Syrian refugees from 1.20 per 100,000 people in 2012 to 11.80 per 100,000 people in 2016. On the contrary, the incidence rate did not change significantly among Jordanians. CONCLUSIONS The incidence rate of leishmaniasis in Jordan has increased in the last three years because of the influx of Syrian refugees into Jordan. A massive effort toward reservoir and vector control, along with actively pursuing diagnosis in endemic foci, will be helpful. Proper and studious reporting of cases is also a necessity for the eradication of this disease.


2017 ◽  
Vol 5 (19) ◽  
Author(s):  
Anshu Babbar ◽  
D. Patric Nitsche-Schmitz ◽  
Dietmar H. Pieper ◽  
Israel Barrantes

ABSTRACT Streptococcus dysgalactiae subsp. equisimilis belongs to the β-hemolytic group C and G pyogenic group of streptococci. Here, we report the draft genome of the S. dysgalactiae subsp. equisimilis strain C161L1 from Vellore, a region in southern India with a high incidence rate of S. dysgalactiae subsp. equisimilis infection. This genome is 2.1 Mb long, with a 39.82% G+C content, and encodes 2,022 genes.


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