scholarly journals The physiological performance of offspring nursing from dams treated with different levels of sodium tungstat

2012 ◽  
Vol 36 (0A) ◽  
pp. 433-49
Author(s):  
Suha A. Rasheed
Keyword(s):  
Weight Gain ◽  
Sodium Tungstate ◽  
Pregnant Female ◽  
Female Rats ◽  
Physiological Performance ◽  
Positive Effects ◽  
Ovary Weight ◽  
The Mean ◽  
Different Levels

This study aimed to recognize the different effects of administration of sodium tungstate in developmental indices of the offspring till weaning. Four groups of Albino Wistar pregnant female rats were used, the first one was control while the remaining three groups intubated with Na- tungstate 75, 150 and 300 mg/ kg/ day respectively since the first day of parturition throughout 21 days. Results referred to an elevation in weight gain of rat dams treated with 75 mg/ kg while weight gain of offspring elevated in both doses of 75 and 300 mg/ kg throughout 21 days, teeth and eye orifice were observed in doses of 75 and 300 mg/ kg faster than control while the mean of ovary weight elevated in both 75 and 300 mg/ kg however the dose 300 mg/ kg revealed the less value of testes weight. The conclusion of present study is that Na- tungstate has positive effects on developmental indices in offspring when administered through nursing until weaning.

Lycopene alleviates western diet-induced elevations in anthropometrical indices of obesity, adipose lipids, and other nutritional parameters

2021 ◽  
pp. 1-9
Author(s):  
Emmanuel Ifeanyichukwu Ugwor ◽  
Adewale Segun James ◽  
Adio Jamiu Akamo ◽  
Dorcas Ibukun Akinloye ◽  
Emmanuel Obinna Ezenandu ◽  
...  
Keyword(s):  
Weight Gain ◽  
Control Diet ◽  
Western Diet ◽  
Female Rats ◽  
Daily Weight Gain ◽  
Anthropometric Parameters ◽  
Nutritional Parameters ◽  
Positive Effects ◽  
Lipid Contents ◽  
Obese Rats

Abstract. Objective: Given the unrelenting surge in the prevalence of obesity and the intensified efforts aimed at elucidating underlying mechanisms and proffering effective treatments, this study investigated the effects of lycopene on various anthropometrical indices of obesity. Methods: Thirty female Wistar rats were equally divided into two groups and fed either control diet or Western diet. After eight weeks, obese rats (fed Western diet) were divided into three groups (n=5); obese control received the vehicle, while the other two received lycopene (0.2 and 0.4 mg/kg body weight, respectively). Normal rats were grouped into three (n=5) and treated similarly. This treatment lasted for another two weeks, in addition to their respective diets. Afterwards, anthropometrical indices were taken. Results: The weight gain, adiposity index, abdominal and thoracic circumference, body mass index, and Lee index were significantly increased (p<0.05) in the obese rats compared to the normal control, by 108.3%, 102.1%, 81.5%, 97.6%, 47.4%, and 13.9%, respectively. The obese rats had significantly (p<0.05) higher adipose tissue lipid contents, daily feed (37.4%) and energy intake (66.0%), daily weight gain (108.3%), and feed efficiency (25.5%) compared to control. However, the treatment of obese rats with lycopene occasioned a dose-dependent reduction in the elevated anthropometrical and nutritional parameters. In addition, lycopene elicited significant reductions (p<0.05), ranging from 16–54%, in the adipose lipid contents. Conclusion: The data presented here illustrate the positive effects of lycopene on indices of obesity and other anthropometric parameters in obese female rats.

OVARIAN ASCORBIC ACID DEPLETION TEST FOR LUTEINIZING HORMONE

1967 ◽  
Vol 56 (4) ◽  
pp. 619-625 ◽  
Author(s):  
Hans Jacob Koed ◽  
Christian Hamburger
Keyword(s):  
Ascorbic Acid ◽  
Luteinizing Hormone ◽  
Dose Response ◽  
Response Curve ◽  
Dose Response Curve ◽  
Human Origin ◽  
Response Curves ◽  
Significant Difference ◽  
The Mean ◽  
Different Levels

ABSTRACT Comparison of the dose-response curves for LH of ovine origin (NIH-LH-S8) and of human origin (IRP-HMG-2) using the OAAD test showed a small, though statistically significant difference, the dose-response curve for LH of human origin being a little flatter. Two standard curves for ovine LH obtained with 14 months' interval, were parallel but at different levels of ovarian ascorbic acid. When the mean ascorbic acid depletions were calculated as percentages of the control levels, the two curves for NIH-LH-S8 were identical. The use of standards of human origin in the OAAD test for LH activity of human preparations is recommended.

scholarly journals Higher Caloric Refeeding Is Safe in Hospitalised Adolescent Patients with Restrictive Eating Disorders

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Elizabeth K. Parker ◽  
Sahrish S. Faruquie ◽  
Gail Anderson ◽  
Linette Gomes ◽  
Andrew Kennedy ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Weight Gain ◽  
Statistical Significance ◽  
Caloric Intake ◽  
Tube Feeding ◽  
Retrospective Chart Review ◽  
Refeeding Syndrome ◽  
Restrictive Eating ◽  
Weight Restoration ◽  
The Mean

Introduction. This study examines weight gain and assesses complications associated with refeeding hospitalised adolescents with restrictive eating disorders (EDs) prescribed initial calories above current recommendations.Methods. Patients admitted to an adolescent ED structured “rapid refeeding” program for >48 hours and receiving ≥2400 kcal/day were included in a 3-year retrospective chart review.Results. The mean (SD) age of the 162 adolescents was 16.7 years (0.9), admission % median BMI was 80.1% (10.2), and discharge % median BMI was 93.1% (7.0). The mean (SD) starting caloric intake was 2611.7 kcal/day (261.5) equating to 58.4 kcal/kg (10.2). Most patients (92.6%) were treated with nasogastric tube feeding. The mean (SD) length of stay was 3.6 weeks (1.9), and average weekly weight gain was 2.1 kg (0.8). No patients developed cardiac signs of RFS or delirium; complications included 4% peripheral oedema, 1% hypophosphatemia (<0.75 mmol/L), 7% hypomagnesaemia (<0.70 mmol/L), and 2% hypokalaemia (<3.2 mmol/L). Caloric prescription on admission was associated with developing oedema (95% CI 1.001 to 1.047;p=0.039). No statistical significance was found between electrolytes and calories provided during refeeding.Conclusion. A rapid refeeding protocol with the inclusion of phosphate supplementation can safely achieve rapid weight restoration without increased complications associated with refeeding syndrome.

scholarly journals Mutual Impact between Clock Gating and High Level Synthesis in Reconfigurable Hardware Accelerators

Electronics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 73
Author(s):  
Francesco Ratto ◽  
Tiziana Fanni ◽  
Luigi Raffo ◽  
Carlo Sau
Keyword(s):  
Low Power ◽  
Integrated Circuit ◽  
Systems Design ◽  
Hardware Acceleration ◽  
High Level Synthesis ◽  
Clock Gating ◽  
Technology Application ◽  
Positive Effects ◽  
High Level ◽  
Different Levels

With the diffusion of cyber-physical systems and internet of things, adaptivity and low power consumption became of primary importance in digital systems design. Reconfigurable heterogeneous platforms seem to be one of the most suitable choices to cope with such challenging context. However, their development and power optimization are not trivial, especially considering hardware acceleration components. On the one hand high level synthesis could simplify the design of such kind of systems, but on the other hand it can limit the positive effects of the adopted power saving techniques. In this work, the mutual impact of different high level synthesis tools and the application of the well known clock gating strategy in the development of reconfigurable accelerators is studied. The aim is to optimize a clock gating application according to the chosen high level synthesis engine and target technology (Application Specific Integrated Circuit (ASIC) or Field Programmable Gate Array (FPGA)). Different levels of application of clock gating are evaluated, including a novel multi level solution. Besides assessing the benefits and drawbacks of the clock gating application at different levels, hints for future design automation of low power reconfigurable accelerators through high level synthesis are also derived.

scholarly journals The Positive Effects of GH-Releasing Peptide-6 on Weight Gain and Fat Mass Accrual Depend on the Insulin/Glucose Status

2010 ◽  
Vol 95 (3) ◽  
pp. 1477-1477
Author(s):  
Miriam Granado ◽  
Cristina García-Cáceres ◽  
Laura M. Frago ◽  
Jesús Argente ◽  
Julie A. Chowen
Keyword(s):  
Weight Gain ◽  
Fat Mass ◽  
Positive Effects ◽  
Glucose Status

scholarly journals The effect of nano-hydroxyapatite/chitosan scaffolds on rat calvarial defects for bone regeneration

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Emmanouil Chatzipetros ◽  
Spyros Damaskos ◽  
Konstantinos I. Tosios ◽  
Panos Christopoulos ◽  
Catherine Donta ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Mean Value ◽  
Parietal Bone ◽  
Female Rats ◽  
Sprague Dawley ◽  
Post Surgery ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
The Right

Abstract Background This study aims at determining the biological effect of 75/25 w/w nano-hydroxyapatite/chitosan (nHAp/CS) scaffolds on bone regeneration, in terms of fraction of bone regeneration (FBR), total number of osteocytes (Ost), and osteocyte cell density (CD), as well as its biodegradability. Methods Two critical-size defects (CSDs) were bilaterally trephined in the parietal bone of 36 adult Sprague-Dawley rats (18 males and 18 females); the left remained empty (group A), while the right CSD was filled with nHAp/CS scaffold (group B). Two female rats died postoperatively. Twelve, 11, and 11 rats were euthanized at 2, 4, and 8 weeks post-surgery, respectively. Subsequently, 34 specimens were resected containing both CSDs. Histological and histomorphometric analyses were performed to determine the FBR, calculated as [the sum of areas of newly formed bone in lateral and central regions of interest (ROIs)]/area of the original defect, as well as the Ost and the CD (Ost/mm2) in each ROI of both groups (A and B). Moreover, biodegradability of the nHAp/CS scaffolds was estimated via the surface area of the biomaterial (BmA) in the 2nd, 4th, and 8th week post-surgery. Results The FBR of group B increased significantly from 2nd to 8th week compared to group A (P = 0.009). Both the mean CD and the mean Ost values of group B increased compared to group A (P = 0.004 and P < 0.05 respectively). Moreover, the mean value of BmA decreased from 2nd to 8th week (P = 0.001). Conclusions Based on histological and histomorphometric results, we support that 75/25 w/w nHAp/CS scaffolds provide an effective space for new bone formation.

Effects of trenbolone acetate and testosterone on growth and on plasma concentrations of corticosterone and ACTH in rats

1990 ◽  
Vol 126 (3) ◽  
pp. 461-466 ◽  
Author(s):  
M. N. Sillence ◽  
R. G. Rodway
Keyword(s):  
Weight Gain ◽  
Growth Response ◽  
Plasma Concentrations ◽  
Female Rats ◽  
Male Rats ◽  
Adrenal Weight ◽  
Trenbolone Acetate ◽  
Male And Female Rats ◽  
Age Related ◽  
Old Rats

ABSTRACT The effects of trenbolone acetate (TBA) on growth and on plasma concentrations of corticosterone were examined in male and female rats. At 5 weeks of age, rats were injected with TBA (0·8 mg/kg) dissolved in peanut oil, or with oil alone, daily for 10 days. In female rats, TBA caused an increase in weight gain (20–38%), a reduction in adrenal weight (19%) and a reduction in plasma concentrations of corticosterone (55%). In contrast, TBA-treated male rats showed no significant increase in weight gain, no significant change in adrenal weight and no reduction in plasma concentrations of corticosterone. The mechanism by which adrenal activity was suppressed in TBA-treated female rats was examined and the response compared with that to testosterone. Female rats (8 weeks old) were injected daily either with oil vehicle, TBA (0·8 mg/kg) or testosterone propionate (0·8 mg/kg). Testosterone increased weight gain (24%), but the growth response to TBA treatment was significantly greater (97%). A reduction in plasma concentrations of corticosterone (45%) was again observed in response to TBA. However, testosterone increased plasma concentrations of corticosterone (52%) above those of control values. Neither androgen affected plasma concentrations of ACTH. Finally, the effects of TBA were examined in 6-week-old female rats, to characterize further the apparent age-related increase in responsiveness. The growth response of 6-week-old rats (60–74%) was intermediate between that seen in 5- and 8-week-old animals. It is concluded that part of the anabolic activity of TBA may be related to a reduction in circulating concentrations of corticosterone. The effect of TBA on corticosterone concentrations differs from that of the natural androgen, testosterone, and does not appear to be mediated by a reduction in plasma concentrations of ACTH. Journal of Endocrinology (1990) 126, 461–466

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