scholarly journals Heat-Intolerance Syndrome subsequent Foot-and-Mouth Disease in Cattle; ThiQar –Iraq

2012 ◽  
Vol 36 (0E) ◽  
pp. 286-292
Author(s):  
Adil M. Abbas
Keyword(s):  
Cortisol Level ◽  
Clinical Signs ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Infected Cattle ◽  
Low Level ◽  
Foot And Mouth ◽  
Radio Immunoassay ◽  
Low Levels ◽  
High Level

The investigation on Heat-Intolerance Syndrome following foot and mouth disease (FMD) infection in cattle in ThiQar–Iraq, used 3ABC FMD ELISA kit, and Radio- immunoassay (RIA) to detect the cortisol level. From 105 there were 65(62%) infected cattle with FMD, which was high at 5- less 8 years old, while the cortrisol level showed three levels; normal (13-21 nmol⁄L), high and low levels were; 6(5.6%), 44(42%) and 55(52%) subsequently. More over the combined result of ELISA and RIA had divided cattle into six groups. First group of 40(38%) cattle infected with FMD and had low level of cortisol, this group containing 21(20%) with clinical signs of heat intolerance. Second group contain 22(21%) FMD infected cattle with high level of cortisol. Third group of 3(2.8%) FMD Infected cattle but normal cortisol level. Fourth group included 3(2.8%) not infected by FMD with normal cortisol level. Fifth group contain 22(21%) not infected with FMD but had high level of cortisol may related to stress. Sixth group consisted 15 (14%) cattle not infected with FMD and had low level of cortisol due to un known cause.Clinical signs of heat intolerance that showed in 21 head of cattle in the first group were: panting, overgrowth of hair coat, emaciation and seeking for shad. The diseased cow known locally as ”Mahrorah” meaning heat-intolerance.

ALTERATIONS IN SOME BIOCHEMICAL PARAMETERS IN CATTLE AFFECTED WITH FOOT AND MOUTH DISEASE IN DAKAHLIA GOVERNORATE, EGYPT

2018 ◽  
pp. 49-56
Author(s):  
Eman Kamal ◽  
MOhamed Salama ◽  
Ahmed Elgamal ◽  
Nabil Heakal
Keyword(s):  
Biochemical Parameters ◽  
Serum Insulin ◽  
Clinical Signs ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Control Group ◽  
Infected Cattle ◽  
Blood Samples ◽  
Foot And Mouth ◽  
Healthy Control

This study was carried out to evaluate the changes in serum biochemical parameters during foot and mouth disease (FMD) viral infection, so blood samples were collected from different farms in Dakahlia Governorate during the outbreak of the disease in 2016. Blood samples were collected after complete clinical and physical examination of twenty five cattle; their ages were ranging from 1-2 years and divided into two groups as follows: 15 cattle were showing the clinical signs of the disease and 10 cattle were clinically healthy (control group). The obtained results showed a significant increase in glucose level (P<0.01), non-esterified fatty acids (NEFA) (P<0.001), beta hydroxyl butyric acid (BHBA) (P<0.001) and lipase enzyme (P<0.01) in infected cattle compared to control group. On the other hand, serum insulin concentration and amylase were significantly lower in blood of infected cattle than control group (P<0.001) and (p<0.01) respectively. from the obtained results it could be concluded that FMD infection in cattle is associated with hyperglycemia, hypoinsulinemia and ketosis

scholarly journals Hemato-Biochemical studies on Egyptian Buffaloes and Calves naturally infected with Foot and Mouth Disease Virus serotype SAT 2

2016 ◽  
Vol 73 (2) ◽  
pp. 230
Author(s):  
Essam A Mahmoud ◽  
Ahmed N.F Neamat-allah
Keyword(s):  
Clinical Signs ◽  
Foot And Mouth Disease ◽  
Viral Disease ◽  
Mouth Disease ◽  
Cardiac Markers ◽  
Mouth Disease Virus ◽  
Virus Serotype ◽  
Foot And Mouth ◽  
Infected Adult ◽  
Apparently Healthy

Foot and mouth disease (FMD) is a highly contagious viral disease of all cloven footed domestic and wild animals. This work was planned to study the different markers for diagnosis of FMDV serotype Sat2 in adult buffaloes and calves including clinical, hematological and biochemical examinations. A total number of sixty animals were divided into four groups. The first group was apparently healthy adult buffaloes, while the second was naturally infected adult buffaloes, a third group was apparently healthy suckling calves and finally the fourth group was naturally infected suckling calves. The recorded clinical signs were fever, salivation, loss of appetite, depression, lameness, blisters or vesicles, erosions and ulcers in the mucosa of the mouth, tongue, lips, gums, pharynx, palate and between the claws. Anemia, leucopenia, lymphopenia and monocytopenia were recorded in infected adult buffaloes and calves. Myocardial injury proved by presence of degenerated myocardial fibers and lymphocyte cell infiltration with a significant increase in cardiac markers like cardiac torponin I, CPK and LDH in addition to a significant hyperkalemia, hypocalcaemia and hypomagnesemia in buffaloe calves. Moreover, electrophoresis showed hyoproteinemia, hypoalbuminemia and hypoglobulinemia in infected animals. It could be concluded that the elevation of cardiac markers emphasized that FMD is more severe in young calves than adult animals. Therefore, it is recommended to evaluate the prognosis of FMD infection in calves by these markers.

scholarly journals Early Detection of Foot-And-Mouth Disease Virus from Infected Cattle Using A Dry Filter Air Sampling System

2015 ◽  
Vol 64 (2) ◽  
pp. 564-573 ◽  
Author(s):  
J. M. Pacheco ◽  
B. Brito ◽  
E. Hartwig ◽  
G. R. Smoliga ◽  
A. Perez ◽  
...  
Keyword(s):  
Early Detection ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Air Sampling ◽  
Mouth Disease ◽  
Infected Cattle ◽  
Sampling System ◽  
Mouth Disease Virus ◽  
Foot And Mouth

scholarly journals Genetic and antigenic variation of foot-and-mouth disease virus during persistent infection in naturally infected cattle and Asian buffalo in India

PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0214832 ◽  
Author(s):  
Jitendra K. Biswal ◽  
Rajeev Ranjan ◽  
Saravanan Subramaniam ◽  
Jajati K. Mohapatra ◽  
Sanjay Patidar ◽  
...  
Keyword(s):  
Disease Virus ◽  
Persistent Infection ◽  
Antigenic Variation ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Infected Cattle ◽  
Mouth Disease Virus ◽  
Foot And Mouth

scholarly journals Identification of Foot-and-Mouth Disease Virus-Specific Linear B-Cell Epitopes To Differentiate between Infected and Vaccinated Cattle

2003 ◽  
Vol 77 (16) ◽  
pp. 8633-8639 ◽  
Author(s):  
Bettina-Judith Höhlich ◽  
Karl-Heinz Wiesmüller ◽  
Tobias Schlapp ◽  
Bernd Haas ◽  
Eberhard Pfaff ◽  
...  
Keyword(s):  
B Cell ◽  
Foot And Mouth Disease ◽  
The United States ◽  
Mouth Disease ◽  
Enzyme Linked Immunosorbent Assay ◽  
Infected Cattle ◽  
B Cell Epitopes ◽  
Foot And Mouth ◽  
Fmdv Strain ◽  
Linear B

ABSTRACT Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. For several years, vaccination of animals, which had proven to be successful for the eradication of the disease, has been forbidden in the United States and the European Community because of the difficulty of differentiating between vaccinated and infected animals. In this study, detailed investigations of the bovine humoral immune response against FMD virus (FMDV) were performed with the aim of identifying viral epitopes recognized specifically by sera derived from FMDV-infected animals. The use of overlapping 15-mer synthetic peptides, covering the whole open reading frame of FMDV strain O1K in a peptide enzyme-linked immunosorbent assay, allowed the identification of 12 FMDV strain O1K-specific linear B-cell epitopes. Six of these linear B-cell epitopes, located in the nonstructural proteins, were used in further assays to compare the reactivities of sera from vaccinated and infected cattle. Antibodies recognizing these peptides could be detected only in sera derived from infected cattle. In further experiments, the reactivity of the six peptides with sera from animals infected with different strains of FMDV was tested, and strain-independent infection-specific epitopes were identified. Thus, these results clearly demonstrate the ability of a simple peptide-based assay to discriminate between infected and conventionally FMD-vaccinated animals.

scholarly journals Recent progress in the diagnosis of foot-and-mouth disease: Rapid field-based assays

2016 ◽  
Vol 72 (6) ◽  
pp. 339-344 ◽  
Author(s):  
Wiesław Niedbalski
Keyword(s):  
Real Time ◽  
Clinical Signs ◽  
Foot And Mouth Disease ◽  
Laboratory Diagnosis ◽  
Mouth Disease ◽  
Diagnostic Methods ◽  
Viral Rna ◽  
Rapid Screening ◽  
Fmdv Serotypes ◽  
Foot And Mouth

The rapid and accurate diagnosis of foot-and-mouth disease (FMD) is critical for effective disease control. Most of laboratory-based methods can provide objective results within a few hours of sample receipt. However, the time taken to transport suspect material to the laboratory can be unacceptably long, often precluding laboratory confirmation in the event of an outbreak. Therefore, rapid and easy-to-perform tests, which can be used in the field (on-site) in case of a suspected disease outbreak, would be a valuable tool for veterinarians in the initial diagnosis of FMDV. The lateral flow immunochromatographic (LFI) test has been efficiently used for the detection of specific antibodies against FMDV non-structural proteins. FMDV serotypes O, A, Asia 1, SAT 2 and non-serotype-specific FMDV. Recently, several FMD-specific real-time RT-PCR (rRT-PCR) assays have been transferred to portable mobile platforms and evaluated for the detection of FMDV in the field: the Cepheid SmartCycler Real-time PCR machine, Enigma FL and LightCycler Nano System. The BioSeeq-Vet (Smiths Detection) was the first commercially available truly portable PCR instrument for the detection of viral RNA in the field. Additionally, a new portable amplification platform Genie I for the on-site detection of viral RNA by reverse-transcription loop-mediated isothermal amplification (RT-LAMP) has also been developed and evaluated. Infrared thermography (IRT), a quantitative method for the assessment of body surface temperature, may also be a useful tool for the early detection of FMDV in the field. In the absence of overt clinical signs, the IRT rapid screening test, which measures heat emission, can be essential in selecting potentially infected animals. Microarrays, a recently introduced technology for the laboratory diagnosis of FMD, offers greater screening capabilities for FMDV detection and can be regarded as an alternative to classical diagnostic methods.

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