scholarly journals Utilization of Elephantopus scaber as traditional medicine and its bioactivity

2021 ◽  
Vol 15 (1) ◽  
pp. 112-118
Author(s):  
Marina Silalahi

Elephantopus scaber has been used various ethnic groups in Indonesia and other countries as traditional medicine. Comprehensive study of the bioactivity of E. scaber is still limited, therefore this paper aims to explain the relationship between the use and its bioactivity. The writing of this article is based on a study of literature published online and offline used keywords E. scaber, bioactivities of E. scaber and uses of E. scaber. Ethnobotanically, E. scaber used to tread wound, nephritis, edema, chest pain, fever, scabies, sores, coughs, tonics, fever, and bronchitis, and asthma. The local communities in China, E. scaber leaves have been developed into "tea" to cure various diseases. The bioactivity of E. scaber is anti-bacterial, anti-fungal, anticancer, hepatoprotective, stimulates hair growth, anti-diabetes mellitus, anti-wound, antioxidant, and overcoming kidney disorders. Deoxyelephantopin is one of the main sesquiterpenes lactones derived from E. scaber has anti-cancer anticancer development. The development of E. scaber tea as an anti-cancer needs to be further investigated because this plant is very easy to find in Indonesia.

2021 ◽  
Vol 7 (1) ◽  
pp. 16-29
Author(s):  
Marina Silalahi

Background: Elephantopus scaber (ES) or tapak liman has been used by various ethnic groups in Indonesia and other countries as traditional medicine. Objectives: Comprehensive review of ES bioactivity is still limited, especially in the Indonesian language. Research Metodes: The writing of this article is based on a study of literature published on line and off line using several keywords Elephantopus scaber, bioactivities of Elephantopus scaber and uses of Elephantopus scaber. Results: In ethnobotany ES used wound medication, treatment of nephritis, edema, humidity, chest pain, fever, scabies, sores, coughs, tonics, fever, and bronchitis, and asthma. In China, ES leaves have been developed into "tea" to cure various diseases. The bioactivity of ES is anti-bacterial, anti-fungal, anticancer, hepatoprotective, stimulates hair growth, anti-diabetes mellitus, anti-wound, antioxidant, anti-neuroinflamation and overcoming kidney disorders. Conclusion: Deoxyelephantopin is one of the main sesquiterpenes lactones derived from ES has anti-cancer anti-cancer development. The development of ES tea as an anti-cancer needs to be further investigated because this plant is very easy to find in Indonesia.   Keywords: Elephantophus scaber, anti-microbial, anti-cancer, deoxyelephantopin


2022 ◽  
Vol 18 (1) ◽  
pp. 001-007
Author(s):  
Marina Silalahi

Eclipta prostrata has been long used by humans as traditional medicine and hair fertilizer. This study aims to explain the relationship between utilization and bioactivity of E. prostrata. The method used is a literature review of articles published online on Google Scholar using the keywords E. prostrata, uses E. prostrata, and bioactivity of E. prostrata. Ethnobotanically, E. prostrata is used to treat liver disorders, liver tonic, respiratory disorders (asthma, cough), hepatitis, snake venom poisoning, and gastritis. In the field of beauty E. prostrata is used to nourish hair and treat baldness. The E. prostrata has bioactivity to treat neurodegeneration, asthma, anti-cancer, overcoming baldness, anti-diabetes mellitus, anti-oxidant, anti-inflammatory, anti-microbial, hepatoprotective, anti-osteoporosis, and anti-hypercholesterolemia. The bioactivity of E. prostrata is related to the content of its secondary metabolite compounds. Echinocystic acid and ecclalbasaponin II from E. prostrata are associated with anti-cancer activity.


2020 ◽  
Vol 7 (2) ◽  
pp. 85
Author(s):  
Marina Silalahi

Tamarindus indica is one of the species in the Fabaceae which is widely used as food and traditional medicine. T. indica has naturalized in Indonesia, especially in Java Island and mostly only used as food, while its use as medicine is still limited. This study aims to explain the relationship between the use of T. indica as a traditional medicine and its bioactivity. The method used in this study is based on literature studies obtained online using the key word Tamarindus indica, uses of T. indica and bioactivities of T. indica. The use of T. indica as a traditional medicine is related to its bioactivity. Bioactivity of T. indica as antimicrobial, antidiabetic mellitus, anti-cholesterol, analgesic, antiobesity and antioxidant. Bioactivity of T. indica as anti-microbial and anti-cancer has the potential to be developed as a food preservative as well as providing healthy effects


2015 ◽  
Vol 2 (1) ◽  
pp. 154 ◽  
Author(s):  
Arliana Fajrin ◽  
Woro Anindito Sri Tunjung

<p>Papaya has widely used as traditional medicine. Papaya leaves and fruits contain flavonoids that can be used as anti-bacterial, anti-fungal and anti-cancer. Flavonoid is one of secondary metabolite products. Flavonoids are ubiquitous in photosynthesis cells. Flavonoid content can be affected by enzyme which arranged from protein, meanwhile difference formation of gene can affect protein content. The aim of this research was to measure flavonoid content in leaves and fruits of genetical engineering papaya (var. California) and local papaya (var. Gandul). Leaf and fruit samples were dried to make powder. Samples were reflucted with HCl 4 N and extracted with Eter (three times). NaNO3 5 %, AlCl3 10 % and NaOH 1 M were added into samples then analyzed using spectrophotometer (á 454 nm) with quercetin as standard. Data analyzed using T test (p &lt; 0,05). The result showed in California leaves has higher concentration of flavonoid (0,73% w/ w ± 0,05) than Gandul leaves (0,69% w/w ± 0,08). meanwhile California fruits significantly has lower flavonoid concentration (0,59% w/w ± 0,02) than gandul fruits (0,8% w/w ± 0,03). Difference of flavonoids content in leaf and fruit indicates genetic variation affect flavonoids translocation among organ. According to variety California fruits have lower concentration than it’s leaves, meanwhile in gandul variety fruits have higher concentration than leaves. In conclusion, difference of flavonoid content in California variety and gandul variety indicates different ability in flavonoids distribution among individual.</p><p><br /><strong>Keywords</strong>: flavonoids, Carica papaya L. var. California, Carica papaya L. var. Gandul, spectrophotometry</p>


2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Marina Silalahi

Backgoun: Syzygium cumini is a species in the Myrtaceae, which is used as traditional medicine. In Indonesia S. cumini found in the yard and home garden, which use as producer of fruit and shading. The using of natural product as traditional medicine is better than sintetic, but improper has a negative impact. This article aims to explain the uses of S. cumini as traditional medicine and its bioactivity. Method: This article is based on the study of literature obtained on line and off line such as used Web, Scopus, Pubmed, and scientific journals, then synthesized according to the research objectives so that comprehensive information. Result: The traditional medicine of S. cumini have been used to cure diabetes mellitus, anti-inflammation, anti-ulcers, vaginal discharge, stomach disorders, fever, stomach aches, wounds, digestive disorders, and skin infection. The bioassay of S. cumini has activities as anti-diabetes mellitus, antioxidant, antimicrobial, anti-allergy, anti-hyperlipidemic, anti-cancer, gastroprotective, hepatoprotective, cardioprotective, anti-inflammatory, and anti-pyretic. Conclusion. Our study of S. cumini is very potential to be developed as an anti-diabetes mellitus drug because it is considered safer therefore it is necessary to do further research.


2020 ◽  
Vol 7 (1) ◽  
pp. 22
Author(s):  
Marina Silalahi

Sida Rhombifolia<em> is one of the species in the Malvaceae family that is widely used as a medicine including the local Indonesian community. This plant is easily found in various fields such as roadsides, yards, gardens and berra land. This study aims to explain the relationship between SR utilization and bioactivity so that it can be used as a source of information in its development. The method used is a literature review in various books and scientific articles that are published online and offline using the keywords Sida Rhombifolia and the bioactivity of S. Rhombifolia. In ethnobotany SR used as traditional medicine include gout, broken bones, wounds, fever, treatment of diarrhea, malaria, gastrointestinal dysentery, fever, asthma, and inflammation and anti-inflammation. SR has bioactivity as an anti-inflammatory, anti-microbial, antioxidant, anti-cancer, drug for kidney disorders, hepatoprotective, anti-diabetes mellitus, and analgesics. The content of tannins, polyphenols, alkaloids, glycosides, flavonoids and saponins found in SR are related to their bioactivity. Utilization of SR as an anti-microbial especially the Enterobacter digestive tract, kidney disorders and anti-cancer can be developed so that it is used as a new alternative source.</em>


2021 ◽  
Vol 6 (2) ◽  
pp. 114
Author(s):  
Marina Silalahi

Urena lobata  is one of the Malvaceae family that has long been used as medicine. This plant is easy to find on the roadside or empty land because it is one of the pioneering vegetation plants, therefore it is very potential to be developed as traditional medicine. The purpose of writing this article is to explain the relationship between the utilization and bioactivity of U. lobata. The method used in writing this article is a review and review of the literature published online. In ethnobotany, U. Lobata is used for fever, rheumatism, wounds, and as an antiseptic. Urena lobata but prominent bioactivity is antimicrobial, antifertility, anti-diabetes Mellitus, and hepatoprotective. The potential and bioactivity of U. lobata as an antifertility for further investigation so that it can be developed to regulate the number of births and is reversible.


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