Hormonal profile assessment in third generation inhabitants living near Semipalatinsk test site

Results of a study covering population of Maisk settlement near Semipalatinsk test site demonstrated possible thyroid diseases in 32.6% of the examinees. Predisposition to autoimmune diseases of thyroid gland (presence of antibodies to thyroid peroxidase) was revealed in 23% of the population. Increased production of stress hormone (cortisol) is characteristic for 39.4% of the females and 37.7% of the males — that is confirmed by changes in the body adaptation system of the third generation inhabitants, if ionizing radiation influence on the previous generations.

Download Full-text

PERTUMBUHAN LARVA DAN PRODUKSI BENIH IKAN KERAPU BEBEK Cromileptes altivelis Valenciennes, 1828 HASIL BUDIDAYA TURUNAN KE-3

Jurnal Ilmu dan Teknologi Kelautan Tropis ◽

10.29244/jitkt.v10i3.20322 ◽

2018 ◽

Vol 10 (3) ◽

pp. 589-600

Author(s):

Regina Melianawati ◽

Ni Wayan Widya Astuti ◽

. Tridjoko

Keyword(s):

Body Weight ◽

Survival Rate ◽

Seed Production ◽

Larval Growth ◽

The Body ◽

Third Generation ◽

Larval Body ◽

Spine Length ◽

The Third ◽

Total Length

ABSTRAKKetersediaan induk dalam suatu usaha pembenihan memiliki peran yang sangat penting. Namun demikian, ketersediaan induk yang berasal dari alam sangat terbatas jumlahnya, sehingga perlu dilakukan penyediaan calon induk yang berasal dari hasil budidaya. Ikan kerapu bebek Cromileptes altivelis Valenciennes, 1828 turunan pertama (F-1) dan turunan kedua (F-2) sudah dapat diproduksi dari hasil budidaya, namun benih turunan ketiga (F-3) belum dapat diperoleh. Penelitian ini bertujuan untuk mendapatkan karakteristik morfologis dan pertumbuhan larva ikan kerapu bebek F-3 sebagai calon induk F-3, serta tingkat keberhasilan produksi benihnya. Pemeliharaan larva dilakukan dalam hatchery hingga larva menjadi benih. Parameter yang diamati meliputi panjang total dan panjang duri sirip larva, berat tubuh larva serta sintasan dan jumlah produksi benih. Hasil penelitian menunjukkan bahwa panjang total larva umur 5, 15, 25 dan 35 hari, masing-masing adalah 3,20±0,07; 4,42±1,11; 8,35±1,12 dan 12,51±3,23 mm. Duri sirip mulai terukur pada larva umur 15 hari. Berat larva umur 30 hari adalah 0,11±0,04 g. Pola pertumbuhan panjang total dan berat tubuh larva adalah eksponensial, sedangkan pola pertumbuhan duri siripnya adalah linier. Masa pemeliharaan larva hingga menjadi benih adalah ± 40 hari. Jumlah benih ikan kerapu bebek F-3 yang diproduksi dalam satu kali siklus pemeliharaan berkisar 440 hingga 2.300 ekor dari 50 ekor induk dan 3 kali siklus pemijahan dengan tingkat kelangsungan hidup 1,30% hingga 8,80%. Hasil penelitian ini mengindikasikan bahwa ikan kerapu bebek F-3 dapat diproduksi dari hasil budidaya seperti halnya pada F-1 dan F-2. ABSTRACTBroodstocks are the most important part of humpback grouper culture, but their availability in nature are limited. Therefore, it is necessary to produce broodstock candidates from culture. The first (F-1) and the second (F-2) generation of humpback grouper have already been produced but the third generation (F-3) production is still on the way. This study was conducted to find out morphological characteristic of the third generation (F-3) of humpback grouper larvae as the candidate of the third generation of broodstock, larval growth and the success rate of seed production. Larvae rearing was done in hatchery until larvae metamorphosed to be seeds. Observed variables including larval total length and spine length, larval body weight, survival rate and the juvenile productions. The study result showed the total length of 5, 15, 25 and 35 days old larvae were 3.20±0.07; 4.42±1.11; 8.35±1.12 and 12.51±3.23 mm, respectively. The spine began measured on 15 days old larvae. The body weight of 30 days old larvae was 0.11±0.04 g. The growth pattern of larval total length and body weight were exponential, while the growth of spine was linear. Rearing period from larvae to juveniles was 40 days. Number of F-3 seed production of humpback grouper produced from once rearing cycle range between 440 and 2,300 fish and the survival rate range from 1.30% up to 8.80%. Therefore, this study could indicate that seed of F-3 humpback grouper can be produced as those of F-1 and F-2.

Download Full-text

Physiological effects of soybeans native and transgenic varieties on the body of the third generation female rats

The Animal Biology ◽

10.15407/animbiol15.03.022 ◽

2013 ◽

Vol 15 (3) ◽

pp. 22-30 ◽

Cited By ~ 5

Author(s):

O. P. Dolaychuk ◽

◽

R. S. Fedoruk ◽

I. I. Kovalchuk ◽

M. I. Khrabko ◽

...

Keyword(s):

The Body ◽

Female Rats ◽

Physiological Effects ◽

Third Generation ◽

The Third ◽

Generation Female

Download Full-text

THE FACTOR OF IONIZING RADIATION AND THYROID CANCER IN WOMEN IN THE ALTAI KRAI

Russian Journal of Oncology ◽

10.18821/1028-9984-2017-22-4-224-228 ◽

2017 ◽

Vol 22 (4) ◽

pp. 224-228

Author(s):

A. F Lazarev ◽

Ya. N Shoikhet ◽

L. F Pisareva ◽

Valentina D. Petrova ◽

S. A Terekhova

Keyword(s):

Thyroid Cancer ◽

Ionizing Radiation ◽

Comparison Group ◽

Test Site ◽

Incidence Rates ◽

Main Group ◽

Female Population ◽

Nuclear Explosions ◽

Semipalatinsk Test Site ◽

Nuclear Tests

The purpose of the study was to study the dynamics of the incidence of thyroid cancer in the female population of the Altai Territory during the period of 1992-2016. Studies were performed with the use of data of the patient register of thyroid cancer, including information on 3026 women, with the use of methods of modern medical statistics. Intensive and standardized indices were calculated for the female population, resided near to traces of nuclear explosions executed at the Semipalatinsk test site, in the zone of the most significant radiation doses (the Main group). As a comparison, incidence rates of the remaining population of the Altai Territory (the Comparison group) and average values for the region were used. The article presents results of a descriptive epidemiological study of the incidence of thyroid cancer in the Altai Territory over 25 years (1992-2016). The results of the probabilistic association of the incidence of thyroid cancer with the ionizing radiation factor due to nuclear tests at the Semipalatinsk test site were obtained. The dynamics of the incidence of thyroid cancer by the data for five-years periods (averaged data): 1992-1996; 1997-2001; 2002-2006; 2007-2011 and 2012-2016 was studied in various territories of the Altai Territory: both on the traces of nuclear explosions - the main group, and in the rest territory (the comparison group), indices of average values for the regions. There were revealed the dynamics of the incidence of thyroid cancer in tens of years after nuclear tests in the population living in the zone with the most significant doses of radiation and its gradual decrease, due to rehabilitation measures. New approaches to the formation of high cancer risk groups for thyroid cancer in the Altai Territory are substantiated.

Download Full-text

CYTOGENETIC CHANGES IN SCHOOLCHILDREN RESIDING IN ECOLOGICALLY ADVERSE REGIONS OF KAZAKHSTAN

Periódico Tchê Química ◽

10.52571/ptq.v17.n35.2020.93_bakhtiyarova_pgs_1137_1147.pdf ◽

2020 ◽

Vol 17 (35) ◽

pp. 1137-1147

Author(s):

Sholpan BAKHTIYAROVA ◽

Bolatbek ZHAKSYMOV ◽

Unzira KAPYSHEVA ◽

Oksana CHEREDNICHENKO

Keyword(s):

Environmental Pollution ◽

Industrial Development ◽

Negative Impact ◽

Genetic Load ◽

Test Site ◽

The Body ◽

Aral Sea ◽

Semipalatinsk Test Site ◽

Wide Range ◽

Younger Generation

In Kazakhstan, due to the strengthening of the geopolitical role in the international arena and active industrial development, negative environmental impacts have intensified in recent years. Many regions are environmentally unfavorable and carry the risk of an increase in the incidence of living in these conditions of the population. Numerous deviations in the health of the community create the conditions for genetic polymorphism and the growth of certain groups of diseases characteristic of regions with environmental pollution. Long-term environmental pollution is the reason for the increase in the rate of the mutation process and the volume of the genetic load in the human population. The purpose of this study is to show the influence of dominant environmental factors in distant regions of Kazakhstan on cytogenetic disturbances in the body of the younger generation. Students from different schools aged 16 to 18 years living near the Semipalatinsk test site of the East Kazakhstan region and in the Aral region of the Kyzylorda region took part in the studies. The results of the study show that the oral epithelial cells in two-thirds of the examined adolescents living in environmentally unfavorable conditions either near the Semipalatinsk Test Site or in the Aral Sea region of Kazakhstan revealed a wide range of cytogenetic disorders. The most significant percentage of violations associated with the formation of micronuclei, protrusions, and apoptosis, was detected in urban students living 150 km from the Semipalatinsk Test Site. When comparing the data of urban and rural students, the predominant development of cytological disorders was revealed, such as nuclear destruction (karyorrhexis, karyolysis, and apoptosis) in rural adolescents, which indicates the ongoing negative impact of the closed Semipalatinsk Test Site and the salinization of the Aral Sea on the health of the younger generation of children.

Download Full-text

Thyroid and adrenal function in children born 5 years after the Chernobyl accident in economically unfavourable regions of Belarus

Problems of Endocrinology ◽

10.14341/probl12162 ◽

1994 ◽

Vol 40 (5) ◽

pp. 22-24

Author(s):

Yu. N. Boiko ◽

A. N. Cherevko ◽

A. M. Petrova ◽

V. K. Zubovich

Keyword(s):

Thyroid Gland ◽

Ionizing Radiation ◽

Adrenal Cortex ◽

Radiation Effects ◽

Radioactive Iodine ◽

The Body ◽

Functional Changes ◽

Cesium Radionuclides ◽

The Republic ◽

Radiosensitive Organs

Currently, there is no doubt the need to study the comprehensive influence of ionizing radiation one the body finctions. Under the influence of ionizing radiation, the development of compensatory and adaptive-adaptive mechanisms of the most radiosensitive organs and tissues to reduce post-radiation effects is of particular importance. Under these conditions, a change in the functional activity of the pituitary-thyroid and adrenal systems is possible, the hormones of which are actively involved in the main adaptation processes. A generally recognized fact is the high radiosensitivity of the above systems, especially in a growing childs body. In the first days after the accident, the main biologically significant radionuclides were iodine isotopes, which caused the formation of dose loads on the thyroid gland. At present, the long-lived radionuclides 13^Cs and 90Sr have a decisive influence on the radiation situation in the republic. The greatest contribution to the radiation dose is made by cesium radionuclides. Some authors studied the functional state of the pituitary-thyroid system in children exposed in 1986 to radioactive iodine in the ante- and postnatal periods. Issues of the occurrence of functional changes in the thyroid gland and adrenal cortex, induced by the intake of radionuclides that are not deposited in these organs, have hardly been studied. Of considerable interest is the study of the state of the functions of the thyroid gland and adrenal cortex in children born and living under the influence of low doses of radiation, whose mothers were exposed to radioactive iodine.

Download Full-text