Admission to hospital with community-onset bloodstream infection during the ‘after hours’ is not associated with an increased risk for death

2010 ◽  
Vol 42 (11-12) ◽  
pp. 862-865 ◽  
Author(s):  
Kevin B. Laupland
2012 ◽  
Vol 23 (4) ◽  
pp. 170-172 ◽  
Author(s):  
Kevin B Laupland ◽  
Pamela C Kibsey ◽  
John C Galbraith

BACKGROUND/OBJECTIVE: Patients admitted to hospital during the ‘after hours’ (weekends and evenings) may be at increased risk for adverse outcome. The objective of the present study was to assess whether community-onset bloodstream infections presenting in the after hours are associated with death.METHODS: All patients in the Victoria area of British Columbia, who had first admissions with community-onset bloodstream infections between 1998 and 2005 were included. The day of admission to hospital, the day and time of culture draw, and all-cause, in-hospital mortality were ascertained.RESULTS: A total of 2108 patients were studied. Twenty-six per cent of patients were admitted on a weekend. Blood cultures were drawn on a weekend in 27% of cases and, in 43%, 33%, and 25% of cases, cultures were drawn during the day (08:00 to 17:59), the evening (18:00 to 22:59) and night (23:00 to 07:59), respectively. More than two-thirds (69%) of index cultures were drawn during the after hours (any time Saturday or Sunday and weekdays 18:00 to 07:59). The overall in-hospital case fatality rate was 13%. No difference in mortality was observed in relation to the day of the week of admission or time period of sampling. After-hours sampling was not associated with mortality in a multivariable logistic regression model examining factors associated with death.CONCLUSION: Presentation with community-onset, bloodstream infection during the after hours does not increase the risk of death.


2021 ◽  
Vol 34 ◽  
pp. 100811
Author(s):  
Rajiv Amipara ◽  
Hana Rac Winders ◽  
Julie Ann Justo ◽  
P. Brandon Bookstaver ◽  
Joseph Kohn ◽  
...  

2020 ◽  
Vol 7 (6) ◽  
Author(s):  
Kylie Martin ◽  
Yves S Poy Lorenzo ◽  
Po Yee Mia Leung ◽  
Sheri Chung ◽  
Emmet O’flaherty ◽  
...  

Abstract Diabetes and left internal jugular vein insertion site were significantly associated with increased risk of a catheter-related bloodstream infection from a tunneled hemodialysis catheter. Ex-smoker status was significantly associated with reduced risk.


2020 ◽  
Author(s):  
Laura Shallcross ◽  
Patrick Rockenschaub ◽  
Ruth Blackburn ◽  
Irwin Nazareth ◽  
Nick Freemantle ◽  
...  

AbstractBackgroundResearch has questioned the safety of delaying or withholding antibiotics for suspected urinary tract infection (UTI) in older patients. We evaluated the association between antibiotic treatment for lower UTI and risk of bloodstream infection (BSI) in adults aged ≥65 years in primary care.MethodsWe analysed primary care records from patients aged ≥65 years in England with community-onset UTI using the Clinical Practice Research Datalink (2007-2015) linked to Hospital Episode Statistics and census data. The primary outcome was BSI within 60 days, comparing patients treated immediately with antibiotics and those not treated immediately.Findings147,334 patients were included representing 280,462 episodes of lower UTI. BSI occurred in 0·4% (1,025 / 244,963) of UTI episodes with immediate antibiotics versus 0·6% (228 / 35,499) of episodes without immediate antibiotics. The odds of BSI were equivalent in patients who were not treated with antibiotics immediately and those who were treated on the date of their UTI consultation (adjusted odds ratio aOR 1·13; 95%-CI: 0·97-1·31). However, delaying or withholding antibiotics was associated with increased odds of death in the subsequent 60 days (aOR 1·17; 95% CI: 1·09-1·26).InterpretationEvidence on the safety of delaying or withholding antibiotics in older adults with suspected UTI is conflicting. Given the prevalence of asymptomatic bacteriuria in this population, their risk of antibiotic-related side effects, and the public health need to tackle antibiotic resistance, we recommend a trial to address this uncertainty.


Infection ◽  
2011 ◽  
Vol 39 (5) ◽  
pp. 405-410 ◽  
Author(s):  
K. B. Laupland ◽  
L. W. Svenson ◽  
D. B. Gregson ◽  
D. L. Church

2007 ◽  
Vol 34 (1) ◽  
pp. 148-151 ◽  
Author(s):  
Andrew Numa ◽  
Gary Williams ◽  
John Awad ◽  
Barry Duffy

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