scholarly journals Upaya Pemenuhan Vaksin Covid-19 Untuk Memutus Rantai Penyebaran Covid-19

2021 ◽  
Author(s):  
Sulton Ali Ma'ruf
Keyword(s):  
Virus Disease ◽  
World Health Organisation ◽  
World Health ◽  
Corona Virus

Tahun 2019 akhir, dunia digemparkan dengan kemunculan virus Corona Virus Disease 2019. Virus ini berasal dari kota Wuhan Provinsi Hubei, China. Perkembangan virus ini tergolong sangat cepat, oleh karena itu World Health Organisation (WHO) menyatakan Covid-19 sebagai pandemi global pada tanggal 11 Maret 2020. Penyebaran virus ini melalui udara atau droplet yang dihasilkan saat batuk ataupun saat bersin. Untuk mempercepat penanggulangan pandemi Covid-19, strategi yang dilakukan adalah pemberian vaksin untuk memberikan imun kepada setiap warga Negara. Pemberian vaksin ini adalah upaya Negara dalam melindungi hak atas kesehatan bagi setiap warga Negara di masa pandemic. Namun masih banyak masyarakat diindonesia yang menolak untuk diberikan vaksinasi Covid-19 karena beredarnya berita HOAX tentang vaksinasi Covid-19 yang menyebabkan masyarakat takut dan ragu untuk dilakukan vaksinasi karena masyarakat beranggapan bahwa vaksinasi Covid-19 itu berbahaya dan dapat menimbulkan kematian. Namun masyarakat Indonesia harus sadar bahwa vaksin Covid-19 sangat penting.

scholarly journals Upaya Pemenuhan Vaksin Covid-19 Untuk Memutus Rantai Penyebaran Covid-19

2021 ◽  
Author(s):  
Sulton Ali Ma'ruf
Keyword(s):  
Virus Disease ◽  
World Health Organisation ◽  
World Health ◽  
Corona Virus

Tahun 2019 akhir, dunia digemparkan dengan kemunculan virus Corona Virus Disease 2019. Virus ini berasal dari kota Wuhan Provinsi Hubei, China. Perkembangan virus ini tergolong sangat cepat, oleh karena itu World Health Organisation (WHO) menyatakan Covid-19 sebagai pandemi global pada tanggal 11 Maret 2020. Penyebaran virus ini melalui udara atau droplet yang dihasilkan saat batuk ataupun saat bersin. Untuk mempercepat penanggulangan pandemi Covid-19, strategi yang dilakukan adalah pemberian vaksin untuk memberikan imun kepada setiap warga Negara. Pemberian vaksin ini adalah upaya Negara dalam melindungi hak atas kesehatan bagi setiap warga Negara di masa pandemic. Namun masih banyak masyarakat diindonesia yang menolak untuk diberikan vaksinasi Covid-19 karena beredarnya berita HOAX tentang vaksinasi Covid-19 yang menyebabkan masyarakat takut dan ragu untuk dilakukan vaksinasi karena masyarakat beranggapan bahwa vaksinasi Covid-19 itu berbahaya dan dapat menimbulkan kematian. Namun masyarakat Indonesia harus sadar bahwa vaksin Covid-19 sangat penting.

scholarly journals Protease Inhibitors: Strategy to Disrupt COVID 19 Contagion

2020 ◽  
Author(s):  
Dhiman C Paul ◽  
minakshi bhattacharjee ◽  
Manash P Sarma
Keyword(s):  
Drug Targets ◽  
Virus Disease ◽  
In Silico Analysis ◽  
World Health Organisation ◽  
World Health ◽  
Plant Origin ◽  
Furin Cleavage ◽  
Corona Virus ◽  
Furin Cleavage Site ◽  
Therapeutic Measures

Abstract Background: The COVID 2019 (Corona Virus Disease) has been currently going pandemic as per WHO (World Health Organisation) situation reports. The major differentiating point in this virus is the presence of a unique furin cleavage site. Our insilico study points out to the effectiveness of a potent plant origin furin inhibitor. We exploited the aspect of the cleavage machinery of furin which is critical and indispensible for the entry of SARS-CoV-2 (Severe Acute Respiratory Syndrome –Corona Virus 2) in human cells and subsequent massive contagion. Most of the drugs are presently targeting ACEII (Angiotensin Converting Enzyme 2) receptor. But these options have injurious effects in diabetics and cardiac patients. Repurposing of old drugs are the current undergoing therapeutic measures as per the EUA (Emergency Usage Administration) of Food and Drug Administration. These aspects could be avoided if we develop a better and safer strategized drug . Methods In silico analysis of plant based protein analogs to inhibit furin protein. Results Significant interactions of proposed analogs of protease inhibitor of plant origin against furin protein. Furin inhibitors would be incredible drug targets against cancers, MERS CoV (Middle East Respiratory Syndrome) and most urgently SARS- CoV-2. Conclusion We report the first of its kind of furin inhibitor and believe that this major finding would fast track arenas for drug trials.

scholarly journals COVID-19: An Epidemiological Puzzle

2020 ◽  
Author(s):  
Subrata Baidya ◽  
Debosmita Paul ◽  
Purvita Chowdhury
Keyword(s):  
Short Communication ◽  
Virus Disease ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Unknown Aetiology ◽  
Corona Virus ◽  
Agent Interaction ◽  
Epidemiological Characteristics ◽  
Associated Variables

A cluster of pneumonia cases of unknown aetiology was reported from Wuhan, Hubei province of China on 31st December, 2019. The World Health Organisation (WHO) declared the outbreak a Public Health Emergency of International Concern (PHEIC) on 30th January, 2020. Thereafter, it has spread through China and reached the level of a pandemic expanding to 210 countries with 77.9M confirmed cases and 1.71M deaths as per Corona virus Disease (COVID-19) situation report issued by WHO based on data received upto 23rdDecember, 2020. A number of questions remain unanswered regarding pathogen-associated variables for amplification dynamics, host environment and agent interaction. This short communication makes an effort to compile the information gathered from published articles of renowned journals and newsletters to explore the epidemiological characteristics of COVID-19. Hereby in this article, authors have tried to assemble the epidemiological lacunae created by the novel characteristics of the SARS-CoV-2 (Severe Acute Respiratory Syndrome-Corona Virus-2) which presently pose a rather puzzling transmission dynamics of COVID-19 that still remain unanswered.

scholarly journals Combat to Corona Virus Disease 2019 COVID-19 Pandemic

2021 ◽  
pp. 406-409
Author(s):  
Arvind Sakwar
Keyword(s):  
Preventive Measures ◽  
Virus Disease ◽  
World Health Organisation ◽  
Mutant Virus ◽  
World Health ◽  
Who Guidelines ◽  
Corona Virus

This paper describes the information of Covid-19 its emergence and declaration of Pandemic by WHO (World Health Organisation). The symptoms and the precautions are also being discussed here. Covid-19 is highly mutant virus that transmits so rapidly and no particular treatment is there to stop it except preventive measures. The initiatives taken by Govt of India are being briefly explained along with WHO guidelines to stopping the expansion of Covid-19.

ASSESSMENT OF PREVAILING FEAR OF CORONA VIRUS DISEASE - 19 IN THE INDIAN POPULATION TOFACILITATE LOCKDOWN RELAXATIONS USING THE FEAR OF COVID-19 SCALE-A STATISTICALAPPROACH.

2021 ◽  
pp. 33-36
Author(s):  
Siva Surya Narayan.S.T.G ◽  
Padmini Sekar ◽  
Venkatesan S
Keyword(s):  
Global Health ◽  
Indian Population ◽  
Virus Disease ◽  
World Health Organisation ◽  
World Health ◽  
Corona Virus ◽  
The World

The ongoing Coronavirus Disease–2019 (COVID-19) pandemic was declared a global health emergency by the World Health Organisation (WHO, 2020)

scholarly journals CONCEPTUAL REVIEW ON THE POTENTIAL OF PUNARNAVADYA GHRITA IN TACKLING THE SYMPTOMS OF COVID-19

2021 ◽  
Vol 12 (3) ◽  
pp. 157-163
Author(s):  
G Siva Ram
Keyword(s):  
Cannabis Sativa ◽  
Virus Disease ◽  
World Health Organisation ◽  
World Health ◽  
Corona Virus ◽  
Global Pandemic ◽  
Phytochemical Compounds ◽  
Effective Remedy

COVID-19 disease has created panic among all with respect to health and economy. On 11th March 2020 WHO (world health organisation) declared novel corona virus outbreak as global pandemic. Confirmed effective remedy to prevent or treat COVID-19 is not yet established. Ayurveda, the Indian system of medicine is the oldest medicinal literature known to mankind as old as 3000 BC and is recognised as medical system by WHO. There is a need to investigate time tested potent classical Ayurvedic formulations backed by contemporary scientific studies in treating symptoms of COVID-19 disease. Vijaya (Cannabis sativa Linn.) in Ayurveda notable for its Vyavayi (quick absorption) and Yogavahi (synergetic action) properties said to be originated from ambrosia as per Vedic mythology. Recent scientific research on the phytochemicals of Cannabis plant showed promising results in decreasing the pro-inflammatory cytokine storm and to an extent halting the replication of SARS-CoV-2. We have put forward one such classical Cannabis Ayurvedic formulation Punarnavadya Ghrita available in market which can be useful as an alternative remedy for prophylactic and curative to the symptoms of novel corona virus disease whose individual herbal phytochemical compounds are studied through in silico, in vitro and in vivo methods in treating COVID-19 with positive outcomes.

scholarly journals Immunomodulatory Effect and Supportive Role of Traditional Herbs, Spices and Nutrients in Management of COVID-19

2020 ◽  
Author(s):  
Luxita Sharma
Keyword(s):  
Traditional Medicine ◽  
Virus Disease ◽  
Supportive Therapy ◽  
Asian Population ◽  
World Health Organisation ◽  
World Health ◽  
Treatment Modalities ◽  
Corona Virus ◽  
Herbs And Spices

Corona Virus disease 2019 (COVID-19) is a new strain of coronavirus that causes respiratory illnesses with a start of flu like symptoms. This disease is fatal and is spread all over the world. The Scientist are working day and night to find vaccine or a cure. World Health Organisation has declared COVID-19 as pandemic [1]. In the view of the pandemic many treatments are being tried on the patients and various treatment modalities are being followed, the traditional medicine has shown a major role to manage this disease. The traditional medicines include the use of herbs, nutrition and spices that are freely available in Asian countries. These are used in day to day life by Asian population [2]. In this paper we have compiled and reviewed the role of various herbs and spices such as Oregano, Ashwagandha, Ginseng, Basil, Sage, Curcumin, Fenugreek, Ginger and Garlic in building immunity and also in curing pathogenic invasions based on evidence based researches. As there is no cure available for COVID-19 till now so supportive therapy is playing a major role for the patients to fight with this pandemic. The AYUSH ministry has also promoted the use of above herbs for a patient suffering from this disease. The corona virus is present in respiratory system as shown by different studies and it has different strains. The guidelines laid by the ICMR and WHO shows that use of herbs, spices and nutrients can be helpful to manage this virus by increasing the immunity in patients. Hence we are not claiming any cures but the herbs and spices used in day to day life are very much effective in management of COVID-19. World Health Organisation (WHO) has recognised the use of alternative and traditional medicine in the management of COVID-19 but the herbs should be used in prescribed amounts and overdose of them can be harmful for health [1,3]. Therefore the present article will enlighten the readers about the role of herbs, spices and nutrients in improving the conditions in COVID-19.

scholarly journals Corona virus epidemiology: a review article

2020 ◽  
Vol 7 (12) ◽  
pp. 5219
Author(s):  
Kamlesh Sharma ◽  
Ram Lal Sharma ◽  
Vanita Sharma
Keyword(s):  
Distress Syndrome ◽  
Preventive Measures ◽  
Virus Disease ◽  
Specific Treatment ◽  
Face Mask ◽  
World Health Organisation ◽  
World Health ◽  
Shortness Of Breath ◽  
Corona Virus ◽  
Respiratory Droplets

Corona virus disease-2019 is an infectious disease caused by SARS-Co-2. The disease started in December 2019 in Wuhan, China resulting in pandemic. Common symptoms are fever, cough and shortness of breath. Loss of apetite, anosmia, conjunctivitis and diarrhoea are fewer common symptoms. The disease is mild in most people but may progress to pneumonia, acute respiratory distress syndrome in elderly patients and those with co-morbidities. The infection is spread from one person to another via respiratory droplets or contact with infected droplets. Preventive measures include frequent and thorough hand washing, maintaining distance from potential transmitter and not touching one’s face. Mask is recommended to suspects and to their caregivers. Presently there is no vaccine or specific treatment for COVID-19. Management involves treatment of symptoms, supportive care. World health organisation declared the 2019-2020 CoV outbreak a pandemic and a Public Health Emergency of International concern with death rate of 3.4%.

CAN HOMOEOPATHY COMBAT COVID-19? A REPERTORIAL VIEW.

2021 ◽  
pp. 27-30
Author(s):  
Suresh Ramalingam ◽  
Maanasa Rajagopalan ◽  
Karthikeyan Pandiyambakkam Rajendran ◽  
Srinivas Govindarajulu ◽  
Antony Rozario
Keyword(s):  
Medical Research ◽  
Clinical Picture ◽  
Virus Disease ◽  
Standard Of Care ◽  
World Health Organisation ◽  
Conclusive Evidence ◽  
World Health ◽  
Health Security ◽  
Indian Council ◽  
Traditional Medicines

Corona virus disease 2019, COVID-19, the ongoing pandemic had resulted in greater loss and had been challenging to the global health security and Health care system. With no curative medicines, repurposing of existing allopathic medicines was widely carried out. Besides Allopathy, traditional medicines and complimentary alternative system of medicines are also being tried and tested everywhere. Management of COVID-19 patients in India is being done according to the guidelines of the Indian Council of Medical Research (ICMR). Under its directives, the Ministry of AYUSH has recommended using Homeopathy drugs as Prophylactic medicines in the name of Immune boosters and also as a Therapeutic agent along with the existing standard of care in the Management of COVID-19 disease. During many previous epidemics Homeopathic medical system has registered its success in both treatment and preventive aspects, which has been recorded in various literatures. Adapting the principles of individualization in an epidemic situation, two major concepts - Genus epidemicus and Similimum through Repertorisation have proved to be viable in embracing homeopathic approach for Prophylactic and Therapeutic measures against COVID-19 respectively. We in this study have used Repertorisation to derive similar remedies for the clinical picture in each concept, to combat COVID-19.The results from the review and repertory have shown Arsenicum album and Phosphorus to have the most similarity with COVID-19 clinical picture of various stages as listed in the World health organisation (WHO) and Indian council of Medical Research (ICMR), based on the two concepts respectively. These remedies prove to have signicant effect as a prophylactic and therapeutic against the COVID-19 disease based on the Genus epidemicus concept, yet it needs scientic clinical trials for stronger and conclusive evidence which have been started and is being done by various homoeopathic hospitals across India

Roles and strategies of international humanitarian organisations in handling the Liberia Ebola outbreak

2019 ◽  
Author(s):  
Jia Bainga Kangbai ◽  
Ahmed Alameldeen
Keyword(s):  
Emergency Preparedness ◽  
Ebola Virus ◽  
Virus Disease ◽  
World Health Organisation ◽  
West African ◽  
World Health ◽  
Healthcare Personnel ◽  
African Countries ◽  
History Of ◽  
Public Health Emergency Preparedness

Abstract Background In Early August 2014, the World Health Organisation declared an Ebola Virus Disease (EVD) outbreak in the region of West Africa. The West African EVD outbreak was the largest, most severe, and complex in the nearly four-decade history of this disease. The management of EVD cases in Liberia was similar to the other affected West African countries. Methods We reviewed the method and strategies used by some of the international humanitarian organisations in handling the 2013-2016 Ebola outbreak in Liberia. This report is a collection of personal field experiences in Liberia as well as personal interviews of healthcare personnel working for some of these international organisations working on the Ebola emergency in Liberia. Findings Medecins Sans Frontieres (MSF) was the first humanitarian NGO to deploy medical staff to the field in Liberia during the 2013-2016 EVD outbreak. MSF staffs were already operating in Liberia even before the declaration of the outbreak in August 2014.Conclusions The slow response by the international humanitarian organisations to lend their support in bringing the EVD outbreak to and exhibited the fear the international community have for deadly infectious diseases more than armed conflicts.Recommendations We recommend regularly training in public health emergency preparedness for third world countries that are highly susceptible to health emergencies such as Ebola outbreak to help prepared them ahead of such outbreak.

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