scholarly journals Alcohol Belongs Here: Assessing Alcohol-related Inhibitory Control with a Contextual Go/No-Go Task

2019 ◽  
Author(s):  
Charlotte Rebecca Pennington ◽  
Rebecca Monk ◽  
Adam Qureshi ◽  
Derek Heim

There is a growing awareness of the need to explore the social and environmental milieus that drive alcohol consumption and related cognitions. The current study examined the extent to which alcohol-congruent and incongruent drinking contexts modulate alcohol-related inhibitory control using a novel Go/No-Go task. One-hundred and eight participants (Mage = 20 years; SD = 4.87) were instructed to inhibit their responses to visual alcoholic (Alcohol/No-Go condition, n = 50) or non-alcoholic stimuli (Alcohol/Go condition, n = 58) depicted in an alcohol-congruent (pub), incongruent (library) or context free (control) condition. Participants in the Alcohol/Go condition exhibited higher false alarm rate (FAR) towards non-alcoholic stimuli and faster reaction times (RT) to alcoholic stimuli depicted in the alcohol-congruent and incongruent context compared to the Alcohol/No-Go condition. In contrast, FAR towards alcoholic stimuli (Alcohol/No-Go condition) were not significantly affected by drinking context but RT was faster when non-alcoholic stimuli were presented in an alcohol-incongruent (i.e., library) compared to alcohol-congruent context (i.e., pub). The discussion turns to potential explanations for these findings, suggesting that social drinkers might exhibit approach tendencies towards alcoholic images that translate into errors towards non-alcoholic stimuli, and that image complexity influences response inhibition.

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mami Miyasaka ◽  
Michio Nomura

Abstract Reward and punishment influence inhibitory performance, but developmental changes in these effects are not well understood. Our aim was to understand the effects of potential reward gains and losses (as indices of reward and punishment) on response inhibition among children and adolescents. We conducted financial and non-financial go/no-go tasks with 40 boys (8- to 15-year-olds). Participants gained or lost money depending on their performance on the financial task, and score rankings were compared to participants on the non-financial task. We found that adolescents’ inhibitory control, as reflected in their reaction times when they made inhibitory errors, was lower in the reward-present condition than in the reward-absent condition, although accuracy was higher when the reward was available for all participants. Additionally, inhibitory control, specifically among adolescents, was higher for financial feedback than for non-financial feedback. These results suggest that the effects of reward and feedback type on motor impulsivity differ as a function of developmental stage. We discuss the theoretical implications of the present findings in terms of the interaction between emotional feedback and response inhibition among children and adolescents.


Author(s):  
Tania Moretta ◽  
Giulia Buodo

AbstractGiven the current literature debate on whether or not Problematic Social Network Sites Use (PSNSU) can be considered a behavioral addiction, the present study was designed to test whether, similarly to addictive behaviors, PSNSU is characterized by a deficit in inhibitory control in emotional and addiction-related contexts. Twenty-two problematic Facebook users and 23 nonproblematic users were recruited based on their score on the Problematic Facebook Use Scale. The event-related potentials were recorded during an emotional Go/Nogo Task, including Facebook-related, unpleasant, pleasant, and neutral pictures. The amplitudes of the Nogo-N2 and the Nogo-P3 were computed as measures of the detection of response conflict and response inhibition, respectively. Reaction times and accuracy also were measured. The results showed that problematic users were less accurate on both Go and Nogo trials than nonproblematic users, irrespective of picture content. For problematic users only, the Nogo-P3 amplitude was lower to Facebook-related, pleasant, and neutral than to unpleasant stimuli, suggesting less efficient inhibition with natural and Facebook-related rewards. Of note, all participants were slower to respond to Facebook-related and pleasant Go trials compared with unpleasant and neutral pictures. Consistently, the Nogo-N2 amplitude was larger to Facebook-related than all other picture contents in both groups. Overall, the findings suggest that PSNSU is associated with reduced inhibitory control. These results should be considered in the debate about the neural correlates of PSNSU, suggesting more similarities than differences between PSNSU and addictive behaviors.


2020 ◽  
Author(s):  
Kaja Faßbender ◽  
Katharina Bey ◽  
Julia V. Lippold ◽  
rene hurlemann ◽  
Ulrich Ettinger

Background: Inhibitory control is a crucial executive function with high relevance to mental and physical wellbeing. However, there are still unanswered questions regarding its neural mechanisms, including the role of the major inhibitory neurotransmitter, γ-aminobutyric acid (GABA). Aims: This study examined the effects of lorazepam (0.5 mg and 1 mg), a positive allosteric modulator at the GABAA receptor, on response inhibition and interference control. We also explored the heterogeneity of inhibitory control and calculated delta plots to explore whether lorazepam affects the gradual build-up of inhibition and activation over time. Method: A sample of N=50 healthy participants performed antisaccade, Eriksen flanker and Simon tasks in a within-subjects, placebo-controlled, double-blind randomised design. Results: Lorazepam increased mean reaction times (MRT) and error rates dose-dependently in all tasks (p≤.005). In the antisaccade and Simon tasks, lorazepam increased congruency effects for error rate (p≤.029) but not for MRT (p≥.587). In the Eriksen flanker task, both congruency effects were increased by the drug (p≤.031). Delta plots did not reflect any drug-induced changes in inhibition and activation over time. Delta plots for MRT in the Simon task were negative-going, as expected, whereas those for the antisaccade and flanker tasks were positive-going. Conclusions: This study provides clear evidence for GABAergic involvement in inhibitory control. Furthermore, our findings highlight the diversity of inhibitory control while also pointing out similarities between different inhibitory control tasks. In contrast to MRTs and error rates, the cognitive processes provided by delta plots appear not to be sensitive to GABAergic modulation.Draft version, 02.04.2020. This paper has not been peer reviewed. Please do not copy or cite without author's permission.


2013 ◽  
Vol 27 (6) ◽  
pp. 507-514 ◽  
Author(s):  
Andrew Jones ◽  
Matt Field ◽  
Paul Christiansen ◽  
Andrej Stancak

2019 ◽  
Vol 33 (6) ◽  
pp. 678-687 ◽  
Author(s):  
Wiebke Bensmann ◽  
Nicolas Zink ◽  
Veit Roessner ◽  
Ann-Kathrin Stock ◽  
Christian Beste

Background: Catecholamines affect response inhibition, but the effects of methylphenidate on inhibitory control in healthy subjects are heterogenous. Theoretical considerations suggest that working memory demands and learning/familiarization processes are important factors to consider regarding catecholaminergic effects on response inhibition. Aims: The purpose of this study was to examine the role of working memory demands and familiarization for methylphenidate effects on response inhibition. Methods: Twenty-eight healthy adults received a single dose of methylphenidate (0.5 mg/kg) or placebo in a randomised, double-blind, crossover study design. The subjects were tested using a working memory-modulated response inhibition paradigm that combined a Go/Nogo task with a mental rotation task. Results: Methylphenidate effects were largest in the most challenging mental rotation condition. The direction of effects depended on the extent of the participants’ task experience. When performing the task for the first time, methylphenidate impaired response inhibition performance in the most challenging mental rotation condition, as reflected by an increased false alarm rate. In sharp contrast to this, methylphenidate seemed to improve response execution performance in the most challenging condition when performing the task for the second time as reflected by reaction times on Go trials. Conclusion: Effects of catecholamines on inhibitory control processes depend on the interplay of two factors: (a) working memory demands, and (b) learning or familiarization with a task. It seems that the net effect of increases in gain control and decreases in working memory processes determines the methylphenidate effect on response inhibition. Hence, crossover study designs likely underestimate methylphenidate effects on cognitive functions.


2017 ◽  
Vol 4 (4) ◽  
Author(s):  
Minchekar Vikas S

The eyewitness is a crucial source of evidence in the criminal judicial system. However, rely on the reminiscence of an eyewitness especially intoxicated eyewitness is not always judicious. It might lead to some serious consequences. Day by day, alcohol-related crimes or the criminal incidences in bars, nightclubs and restaurants are increasing rapidly. Tackling such cases is very complicated to any investigation officers. The people in that incidents are violated due to the alcohol consumption hence, their ability to identify the suspects or recall these phenomena is affected. The studies on the effects of alcohol consumption on motor activities such as driving and surgeries have received much attention. However, the effect of alcohol intoxication on memory has received little attention from the psychology, law, forensic and criminology scholars across the world. In the Indian context, the published articles on this issue are equal to none up to present day. This field experiment investigation aimed at to finding out the effect of alcohol consumption on identification accuracy in lineups. Thirty adult social drinkers, and thirty sober adults were randomly recruited for the study. The sober adults were assigned into “placebo” beverage group while social drinkers were divided into two group e. g. “low dose” of alcohol (0.2 g/kg) and “high dose” of alcohol (0.8 g/kg). The social drinkers were divided in such a way that their level of blood-alcohol concentration (BAC) will become different. After administering the beverages for the placebo group and liquor to the social drinkers for 40 to 50 minutes of the period the five-minute video clip of mock crime is shown to all in a group of four to five members. After the exposure of video clip subjects were given 10 portraits and asked them to recognize whether they are involved in mock crime or not. Moreover, they were also asked to describe the incident. The subjects were given two opportunities to recognize the portraits and to describe the events; the first opportunity is given immediately after the video clip and the second was 24 hours later. The obtained data were analyzed by one-way ANOVA and Scheffe’sposthoc multiple comparison tests. The results indicated that the “high dose” group is remarkably different from the “placebo” and “low dose” groups. But, the “placebo” and “low dose” groups are equally performed. The subjects in a “high dose” group recognized only 20% faces correctly while the subjects in a “placebo” and “low dose” groups are recognized 90 %. This study implied that the intoxicated witnesses are less accurate to recognize the suspects and also less capable of describing the incidents where crime has taken place. Moreover, this study does not assert that intoxicated eyewitness is generally less trustworthy than their sober counterparts.


TAPPI Journal ◽  
2014 ◽  
Vol 13 (1) ◽  
pp. 33-41
Author(s):  
YVON THARRAULT ◽  
MOULOUD AMAZOUZ

Recovery boilers play a key role in chemical pulp mills. Early detection of defects, such as water leaks, in a recovery boiler is critical to the prevention of explosions, which can occur when water reaches the molten smelt bed of the boiler. Early detection is difficult to achieve because of the complexity and the multitude of recovery boiler operating parameters. Multiple faults can occur in multiple components of the boiler simultaneously, and an efficient and robust fault isolation method is needed. In this paper, we present a new fault detection and isolation scheme for multiple faults. The proposed approach is based on principal component analysis (PCA), a popular fault detection technique. For fault detection, the Mahalanobis distance with an exponentially weighted moving average filter to reduce the false alarm rate is used. This filter is used to adapt the sensitivity of the fault detection scheme versus false alarm rate. For fault isolation, the reconstruction-based contribution is used. To avoid a combinatorial excess of faulty scenarios related to multiple faults, an iterative approach is used. This new method was validated using real data from a pulp and paper mill in Canada. The results demonstrate that the proposed method can effectively detect sensor faults and water leakage.


Author(s):  
Sherif S. Ishak ◽  
Haitham M. Al-Deek

Pattern recognition techniques such as artificial neural networks continue to offer potential solutions to many of the existing problems associated with freeway incident-detection algorithms. This study focuses on the application of Fuzzy ART neural networks to incident detection on freeways. Unlike back-propagation models, Fuzzy ART is capable of fast, stable learning of recognition categories. It is an incremental approach that has the potential for on-line implementation. Fuzzy ART is trained with traffic patterns that are represented by 30-s loop-detector data of occupancy, speed, or a combination of both. Traffic patterns observed at the incident time and location are mapped to a group of categories. Each incident category maps incidents with similar traffic pattern characteristics, which are affected by the type and severity of the incident and the prevailing traffic conditions. Detection rate and false alarm rate are used to measure the performance of the Fuzzy ART algorithm. To reduce the false alarm rate that results from occasional misclassification of traffic patterns, a persistence time period of 3 min was arbitrarily selected. The algorithm performance improves when the temporal size of traffic patterns increases from one to two 30-s periods for all traffic parameters. An interesting finding is that the speed patterns produced better results than did the occupancy patterns. However, when combined, occupancy–speed patterns produced the best results. When compared with California algorithms 7 and 8, the Fuzzy ART model produced better performance.


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