scholarly journals Microfilaria in Cytological Smears at Rare Sites Coexisting with Unusual Pathologies - A Series of Eight Cases

2016 ◽  
Vol 2 (1) ◽  
pp. 28-31
Author(s):  
Mani Krishna ◽  
Seema Dayal
Keyword(s):  
Salivary Gland ◽  
Rural Areas ◽  
Blood Smear ◽  
Incidental Finding ◽  
Peripheral Blood Smear ◽  
The Body ◽  
Major Health Problem ◽  
Major Health ◽  
Arm Swelling ◽  
Blood Smear Examination

Microfilaria infection is one of the major health problem in developing countries like India, especially in rural areas. In most of the cases microfilaria was an incidental finding in FNAC smears prepared from swellings from various locations in the body and also from fluid aspirate. Peripheral blood smear examination is usually done for the diagnosis. Here, we presented a series of eight cases with very unusual and rare locations. We found microfilaria in subcutaneous arm swelling, pleural effusion, axillary swelling, breast and salivary gland. All cases were rare and unique.

scholarly journals Evaluation on the presence of Anaplasma, Ehrlichia, and Babesia spp. in goats (Capra hircus) in Cebu, the Philippines

2019 ◽  
Vol 12 (6) ◽  
pp. 774-777 ◽  
Author(s):  
Adrian P. Ybañez ◽  
Orgil V. Arrabis ◽  
Dennis Justin M. Alvarez ◽  
Eloiza May S. Galon ◽  
Rhea Mae P. Jayag ◽  
...  
Keyword(s):  
Blood Smear ◽  
Peripheral Blood Smear ◽  
The Philippines ◽  
Capra Hircus ◽  
Chain Reaction ◽  
Nested Polymerase Chain Reaction ◽  
Blood Samples ◽  
Blood Smear Examination ◽  
Polymerase Chain ◽  
Babesia Spp

Background: Tick-borne diseases are caused by a wide variety of viruses, pathogens, and diseases. Anaplasma, Ehrlichia, and Babesia spp. are among the most known tick-borne pathogens in Asia. In the Philippines, these pathogens were already reportedly present in dogs and large ruminants, but no study has been reported yet evaluating their presence in goats. Aim: The present study aimed to evaluate the presence of Anaplasma, Ehrlichia, and Babesia spp. in goats in Cebu, the Philippines. Materials and Methods: A total of 100 blood samples from goats were collected in Cebu, the Philippines. Profile of sampled goats including age, body score, and sex was obtained. Peripheral blood smear examination and DNA extraction were performed. Nested polymerase chain reaction assay was used to evaluate the presence of Anaplasma, Ehrlichia, and Babesia spp. Results: None of the samples were found positive with Anaplasma, Ehrlichia, and Babesia spp. infection. Conclusion: Tested goats were negative with Anaplasma, Ehrlichia, and Babesia spp. and calls for continuous surveillance of these pathogens due to the reported detection of these pathogens in other livestock animals in the area.

scholarly journals Erythrocyte Morphology in Women of Reproductive Age (WORA) with Anemia

Biomedika ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 83-91
Author(s):  
Alex Jekson Tukira ◽  
Lucia Sincu Gunawan ◽  
Edy Prasetya
Keyword(s):  
Peripheral Blood ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
Reproductive Age ◽  
Target Cells ◽  
Women Of Reproductive Age ◽  
Erythrocyte Morphology ◽  
Smear Examination ◽  
Blood Smear Examination ◽  
Laboratory Technology

Anemia is a decrease in the number of erythrocytes in the blood circulation or the level of hemoglobin that is less than normal. The three major body mechanisms that cause anemia are excessive destruction of erythrocytes, blood loss, and decreased erythrocyte production. Based on the Basic Health Research (Riskesdas) in 2013, the prevalence of anemic women of reproductive age (WORA) aged 15-44 years in Indonesia was 35.3%. Anemia is classified based on the morphology of erythrocytes, including hypochromic microcytic, normocytic normochromic, and macrocytic. Erythrocyte morphology can be observed using peripheral blood smear examination. The objective of this study was to determine the morphology of erythrocytes in anemic women of reproductive age. This study belongs to descriptive research. The population of the study was 136 women of reproductive age, covering the students of D-IV in Medical Laboratory Technology at Setia Budi University. Forty-one respondents suffering from anemia were taken using a purposive sampling technique. The types of anemia were determined with examination using an Easy Touch hemoglobinometer with the Hb level of less than 12g/dL. Preparation of peripheral blood smear examination using EDTA venous blood and stained with Giemsa. Microscopic examination was performed with 1000x objective magnification. The peripheral blood smear reading showed the erythrocyte morphology that includes normocytic normochromic (38 samples or 93%), microcytic hypochromic (three samples or 7%), and poikilocytosis consisting of teardrop cells, target cells, ellipstocytes, and stomatocytes (five samples or 18%). Further study is required to investigate the correlation of erythrocyte index and peripheral blood smear in anemia.

scholarly journals Hematological and biochemical profile of person with macrocytic anemia in a tertiary health care centre of Nepal

2020 ◽  
Vol 10 (2) ◽  
pp. 1722-1727
Author(s):  
Rakesh Pathak ◽  
Sujata Pudasaini ◽  
Sushmita Ghimire ◽  
Anil Singh Basnyat ◽  
Anuj KC
Keyword(s):  
Folic Acid ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Peripheral Blood ◽  
Blood Smear ◽  
Hematological Parameters ◽  
Macrocytic Anemia ◽  
Peripheral Blood Smear ◽  
Blood Smear Examination ◽  
Red Blood Cell Indices

Background: Anemia is a nutritional problem worldwide with an increased risk of morbidity and mortality in all age groups. Macrocytic anemia often originates from abnormalities that impair the erythroid precursor maturation in the bone marrow. Since the clinical manifestations of different types of anemias are similar, hematological parameters including hemoglobin, Red blood cell indices, and Peripheral Blood Smear examination are useful in the diagnosis of anemia. Materials and Methods: This was a cross-sectional study done in the Department of Pathology at Nepal Medical College Teaching hospital. A total of 42 patients between 14 to 62 years with low Hb concentration according to the World Health Organization criteria for anemia were selected and a mean cell volume > 100 fL was taken for study. Peripheral blood smear examination, Red blood cell indices, Vitamin B12, and Folic acid level were evaluated. Results: There were 42 patients with macrocytic anemia enrolled in the study with a mean age of 31.85±12.49 years and with female preponderance. Hemoglobin level was slightly low in males compared to females. Red blood cell indices were slightly higher in males. The difference of serum Vit B12 and Folic acid in male and female was found to be significant. Conclusions: It was concluded that for the diagnosis of a specific type of anemia, hemoglobin, Red blood cell indices, reticulocytes percent, and PBS examination were important parameters. Serum Folic acid and Vitamin B12 level estimation along with other hematological parameters are important for the diagnosis of macrocytic anemia and its correlation

scholarly journals Profile of alopecia areata in patients attending dermatology out patient department in a tertiary care hospital in Gangtok, Sikkim

2021 ◽  
Vol 7 (6) ◽  
pp. 782
Author(s):  
Nisha Gupta ◽  
Rekha Sharma ◽  
Rukma L. Sharma
Keyword(s):  
Alopecia Areata ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
The Body ◽  
Care Hospital ◽  
Age Group ◽  
Major Health Problem ◽  
Major Health ◽  
Male Preponderance ◽  
Patient Department

<p><strong>Background:</strong> Alopecia areata is a condition that is characterized by a well-defined round or oval patches of non-scaring hair loss in scalp or any hairy area of the body. Alopecia areata has become a major health problem faced by people all over the world. This research was done to ascertain the prevalence of alopecia areata in different age group and to study its association with autoimmune diseases and systemic illnesses.</p><p><strong>Methods:</strong> The present hospital based descriptive study includes 52 alopecia areata patients attending dermatology out-patient department.</p><p><strong>Results:</strong> It was seen that the disease can occur at any age group mostly affecting those between 21-40 years. The age of presentation varied from 14 to 48 years with male preponderance. It was found that arthritis was associated in 30.7%, ANA was positive in 7.7% and 12% had hypothyroidism. Eosinophilia was found in 34.6% and 7.7% had asthma among then.</p><p><strong>Conclusions:</strong> Our study shows that it could be associated with autoimmunity, thyroid abnormality, atopy and inflammation.</p>

scholarly journals Comparison of quinine-doxycycline and quinine-clindamycin for falciparum malaria in children

2011 ◽  
Vol 51 (4) ◽  
pp. 187
Author(s):  
Ditho Athos P. Daulay ◽  
Yunnie Trisnawati ◽  
Syamsidah Lubis ◽  
Munar Lubis ◽  
Syahril Pasaribu
Keyword(s):  
Falciparum Malaria ◽  
Peripheral Blood ◽  
Blood Smear ◽  
Controlled Trial ◽  
Peripheral Blood Smear ◽  
Combination Group ◽  
Cure Rate ◽  
Doxycycline Treatment ◽  
Blood Smear Examination

Objective To compare the efficacy of quinine-doxycycline to quinine-clindamycin combination, as treatment for uncomplicated falciparum malaria in children.Methods This randomized open labelled controlled trial was conducted from July to August 2007 at Mandailing Natal, Sumatera Utara Province. The subjects were 8 – 18 year old children with positive Plasmodium falciparum from the peripheral blood smear. Simple randomization was performed to determine subject study into two groups of treatment, one group received quinine-clindamycin and the other received quinine-doxycycline treatment. The parasitemia was counted on day 0, 2, 7 and 28. We also observed the adverse effects of the antimalarial combination.Results Two hundred and forty six children who fulfilled the inclusion criteria were divided into two groups. All subjects completed the study. Cure rate achieved 100% from peripheral blood smear examination at the second day observation and showed no recrudescence at day 28th. (P=0.0001). During 28 days follow up, there were 21 (17.6%) patients suffered from headache, 18 (14.6%) vomit and 40 children (32.5%) suffered from tinnitus in quinine-doxycycline combination, compared to quinine-clindamycin combination group only 4 (3.3%) suffered from headache, 1 (0.8%) suffered from tinnitus and there was no vomiting experience in any patient (P < 0.0001).Conclusion Combination of quinine with either clindamycin or doxycycline are effective as an alternative antimalarial treatment. The combination of quinine-clindamycin is well tolerated than the combination of quinine-doxyciline, and this combination may be particular value for young children and pregnant women, as these two groups cannot receive doxycycline.

Screening peripheral blood smear: A tale of the “TAIL”

2021 ◽  
pp. 004947552098638
Author(s):  
Neha Garg ◽  
Shilpi More ◽  
Parul Chopra ◽  
Richa Gupta ◽  
Mrinalini Kotru
Keyword(s):  
Early Diagnosis ◽  
Low Power ◽  
High Power ◽  
Peripheral Blood ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
The Body

Examining a well-stained slide in a systematic manner is the key to being a good pathologist. For a blood smear, it involves examining first at low power (40× or 100×) for broader details and then going on to high power (400×) for finer details, from the tail end to the body of the slide. The ‘tail end’ is the key to early diagnosis.

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