scholarly journals Evaluation of blood groups in patients with anti TPO positive

2019 ◽  
Vol 10 (6) ◽  
pp. 67-70 ◽  
Author(s):  
Eşref Araç ◽  
İhsan Solmaz
Keyword(s):  
Diabetes Mellitus ◽  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Negative Group ◽  
Positive Group ◽  
Group System ◽  
The Relationship ◽  
B Blood Group

Background: In studies, ABO blood group system has been shown to be associated with type 2 diabetes mellitus, chronic renal failure, gestational diabetes mellitus, postpartum depression, coronary artery disease, Crohn’s disease as well as various cancer types such as stomach, breast, skin cancers and rheumatologic diseases. Aims and Objective: The relationship between anti TPO positivity and ABO blood group system is aimed to be investigated by using blood groups which are the product of genetic structure and easy to identify by considering the relationship between anti TPO positivity and blood group. Materials and Methods: 4312 patients with determined blood groups were included among the patients, who were admitted to the internal medicine outpatient clinics of our hospital between January 2, 2017 and May 28, 2019 and were screeened for thyroid antibodies with thyroiditis susceptibility. Results: The most common blood group was A in both anti TPO positive and anti TPO negative patient groups.The rate of those with O blood group was 2.65% higher in anti TPO positive group than anti TPO negative group. B blood group was found to be 4.87% higher in anti TPO negative group than anti TPO positive group (p:0.148). Conclusion: In conclusion, it was found that O blood group may be a risk factor for anti TPO positivity and B blood group is much lower in anti TPO positive ones. However, it is obvious that more comprehensive prospective multicentered clinical and experimental studies are needed to establish the relationship between blood groups and autoimmune diseases, especially autoimmune thyroiditis.

scholarly journals Prevalence of ABO and Rh blood groups and their association with Transfusion-Transmissible Infections (TTIs) among Blood Donors in Islamabad, Pakistan

2021 ◽  
Vol 3 (4) ◽  
Author(s):  
Muhammad Yousaf Khan ◽  
Farwa Sijjeel ◽  
Ahmareen Khalid ◽  
Rukhshan Khurshid ◽  
Umm E Habiba ◽  
...  
Keyword(s):  
Viral Infection ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Syphilis Infection ◽  
Group System ◽  
Group A ◽  
Group B

Certain Rh positive blood groups showed a link between the ABO blood grouping and susceptibility to some infectious ailments. Study was carried out to find the association of ABO Blood Group System / Rh type with different viral infection. A retrospective observational study was carried in 7631 blood donors to find the association of ABO Blood Group System / Rh type with viral infection due to hepatitis B virus, hepatitis C virus, human immunodeficiency virus and Syphilis. Data of the study indicateF that the highest incidence of blood group in blood donor was B followed by O, A and AB. The incidence of HBsAg +ve, HCV Ab +ve and infection of Syphilis was also highest in donor with blood group B followed by O, A and AB. Blood group A were more susceptible to HIV Ab +ve followed by blood group B, O and AB. The group B donors had the greatest risk of viral infection with HBV, HCV, HIV, and Syphilis; followed by the groups O, A, and AB. Donors in group AB had the lowest incidence rate of all viral infection. The study revealed that blood group B is most prevalent among donors, followed by blood groups O, A, and AB. On the other side, the rate of HBV, HCV, HIV, and Syphilis infection was greatest among group B donors, followed by group O, group A, and group AB. Copyright(c) The Authors

scholarly journals ABO blood group system and occurrence of ischemic stroke

2021 ◽  
Author(s):  
Rafaella Chiodini LOTZ ◽  
Carolina da Silveira WELTER ◽  
Silvia Aparecida RAMOS ◽  
Leslie Ecker FERREIRA ◽  
Norberto Luiz CABRAL ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Blood Group ◽  
Cerebrovascular Diseases ◽  
Blood Groups ◽  
Blood Type ◽  
Control Group ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Abo Blood Groups ◽  
Group System

ABSTRACT Background: Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well established. Objective: For that reason, the purpose hereof was to investigate the relation between the ABO blood groups and the occurrence of IS in a Brazilian cohort of cerebrovascular diseases. Methods: Five hundred and twenty-nine subjects were included over 12 months, from which 275 presented an IS episode and 254 composed the control group. Blood samples were drawn for direct and reverse serotyping. The control and IS groups were compared regarding the traditional risk factors and the distribution of the ABO blood groups. Results: The IS group presented a higher prevalence of systemic arterial hypertension (SAH), diabetes mellitus, smoking habits, family history, cardiopathy, and sedentary lifestyle in comparison with the control group. The AB blood type prevailed among the patients (5.1 vs. 1.6%; p<0.05) and this group had more SAH cases in comparison with the O type group (92.9 vs. 67.3%; p<0.05). Conclusions: Our results suggest that the occurrence of IS is more frequent among patients of the AB blood type.

Predictive and prognostic effect of ABO blood group on immune checkpoint inhibitors

2021 ◽  
pp. 1-8
Author(s):  
Yakup Ergun ◽  
Selin Akturk Esen ◽  
Murat Bardakci ◽  
Gokhan Ucar ◽  
Ziya Kalkan ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Blood Group ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Advanced Malignant Melanoma ◽  
The Relationship

BACKGROUND: The relationship of the ABO blood group system with the immune response is known, but its relationship with immune checkpoint inhibitors (ICIs) has not been clearly investigated until now. OBJECTIVE: In this study, the relationship between different blood groups and nivolumab treatment response in patients with advanced malignant melanoma was investigated. METHODS: The data of patients who used nivolumab for advanced malignant melanoma between April 2018 and April 2021 were retrospectively reviewed. RESULTS: A total of 73 patients were included in the study. In the progression-free survival (PFS) analysis according to blood groups, it was 3.9 months, 16.1 months, 20.0 months and 3.0 months for A, B, AB and O, respectively (p= 0.1). Overall survival (OS) analysis according to blood groups was 5.1 months, 25.0 months, 20.0 months and 9.3 months for A, B, AB and O, respectively (p= 0.1). The B antigen group (B or AB) had significantly longer PFS and OS than the non-B antigen group (A or O) (16.1 vs. 3.5 months for PFS, respectively, p= 0.03; 20.0 vs. 7.4 months for OS, respectively, p= 0.02). CONCLUSIONS: The presence of B antigen provides a significant advantage in terms of survival in patients using ICIs for advanced melanoma.

scholarly journals Blood Group Susceptibility towardsCOVID-19 and Other Diseases

2021 ◽  
Vol 3 (2) ◽  
pp. 171-176
Author(s):  
Renuka Sharma ◽  
Manpreet Kaur ◽  
Manpreet Kaur ◽  
Neeru ◽  
Neha Yadav ◽  
...  
Keyword(s):  
Blood Group ◽  
Respiratory Diseases ◽  
Large Family ◽  
Future Research ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Blood Group Antigens ◽  
Group System ◽  
Relationship Of ◽  
The Relationship

COVID – 19 is a global pandemic caused by a coronavirus named SARS CoV -2. A large family of viruses that causes severe respiratory diseases known as Coronavirus (CoVs) show symptoms such as common cold and range to more rare and severe respiratory diseases such SARAS i.e Severe Acute Respiratory Syndrome and MERS i.e Middle East Respiratory Syndrome detected for the first time in 2003 and 2012, respectively. It is expected to be a zoonotic virus transmitted via bats categorically, from genus Rhinolophus and closely related animals to humans. As this life threatening pandemic started from the Wuhan city of China, and the examination about this disease is still in continuity. It is very important to explore all possible scientific key points regarding this disease to eradicate such a dangerous issue from the society and to save the human race on earth. Literature available till now confirmed that the ABO blood group system showed significant relationship with various diseases. Now, scientific communities were working on different aspects of COVID-19 disease. But by keeping in mind about the severity of this disease and the relationship of blood group system of humans with infectious disease we conducted this study. Present review is designed to explore the relationship of COVID-19 alongwith other disease with the ABO blood group and Von Willebrand Factor. This study will provide information about the scientific evidences regarding the role of blood group antigens in prognosis of COVID-19 alongwith other disease and this can be significant for future research.

scholarly journals COVID-19 and blood groups: A six-months observational study in Ferrara, Italy

2021 ◽  
Vol 13 (3) ◽  
Author(s):  
Salvatore Greco ◽  
Nicolò Fabbri ◽  
Alessandro Bella ◽  
Beatrice Bonsi ◽  
Alessandra Violi ◽  
...  
Keyword(s):  
Blood Group ◽  
Cox Regression ◽  
Laboratory Data ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Survival Functions ◽  
Group System ◽  
Hospital Stays ◽  
A Minor

The current literature still gives a little information about the relationships between the ABO blood group system and the immune response to the virus or the different disease outcomes. Hypothesizing the presence of a predisposition by some blood groups to COVID-19, we searched for differences between patients towards the different outcomes of disease.We enrolled 330 inpatients with a diagnosis of COVID-19, determining both their ABO blood group system and Rh factor, collecting demographic, clinical and laboratory data. We searched for relationships with COVID-19 outcomes within an observation period of 180 days (Intensification of Care - IoC, Inhospital death, 180-days mortality). The most frequent ABO blood group was A (45.8%); a minor part was represented by group O (38.8%), B (11.5%), AB (3.9%). As for the Rh factor, 86.7% of patients were Rh-positive. There were no significant differences between blood groups and Rh factors as for age, length of hospital stays (LoS), or Charlson Comorbidity Index (CCI), nor we found significant relationships between the ABO groups and COVID-19 outcomes. A significant relation was found between AB group and IoC (p=0.03) while as for the Rh factor, the patients with Rh factor positive died with less frequency during the stay (p=0.03). Cox regression analyses showed substantial differences in the survival functions concerning the Rh factors. The Rh factor seems to be involved in the 180-day prognosis. The survival functions of patients with Rh factor positive show, in fact, significantly better curves when compared to those with Rh factor negative.

scholarly journals The ABO Blood Group System and Plasmodium Infection in Iran: A Comprehensive Study

2019 ◽  
Author(s):  
Farshid Karami ◽  
Mozhdeh Mohammadian ◽  
Seif Ali Mahdavi ◽  
Mohammad Taghi Rahimi
Keyword(s):  
Blood Group ◽  
Geographical Distribution ◽  
Significant Relationship ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Plasmodium Infection ◽  
Group System ◽  
Group Distribution ◽  
Comprehensive Study

Background: Geographical distribution of ABO blood groups affects by race, ethnicity, migration and some infectious agents, such as Plasmodium species. P. falciparum is the major causative agent of death in malaria that can affect ABO blood group distribution in different populations. Therefore, the objective of the current study was to determine the effect of p. falciparum on ABO blood group distribution in Iran. Materials & Methods The present study was conducted on the database of Iranian Blood Transfusion Organization (IBTO) in 30 provinces of the country about ABO and Rh blood groups of the people who referred to health centers from June 2011 to August 2012.   Results: A total number of 2124560 individuals were referred to IBTO in 30 provinces. The highest and lowest rates of O blood group were observed in Sistan & Baluchestan (64.6%) and Lorestan (37.7%), respectively. P. falciparum was the most common species of malaria in Sistan & Baluchestan (53215) and the rarest infection agent in Semnan province (20). The results showed statistically significant relationship (p < 0.05) between prevalence of P. falciparum with O blood group, while this relationship for a blood group was not significant (p > 0.05). Conclusion: Our results revealed a significant relationship between prevalence of P. falciparum and geographical distribution of ABO blood. There was also found more susceptibility and risk to malaria infection and cerebral malaria in a blood group compared to other groups. In addition, this was the first comprehensive study on the ABO blood group system and Plasmodium infection in Iran.

An Insight into the General Trend of Blood Group Dissemination among Local Population of Muzaffarabad

2020 ◽  
pp. 39-43
Author(s):  
OJS Admin
Keyword(s):  
Blood Group ◽  
Disease Susceptibility ◽  
General Trend ◽  
Local Population ◽  
Blood Groups ◽  
Blood Group System ◽  
Group System ◽  
Insight Into

Blood groups ABO and Rhesus, constituting the most principal blood group system, are of key signicance for clinical and transfusion practices and are moreover, thought to be associated with disease susceptibility.

scholarly journals Association of Blood Groups with Oral Submucous Fibrosis and if any of the Blood Group is Related with an Increased Risk for Oral Submucous Fibrosis

2021 ◽  
Vol 15 (10) ◽  
pp. 2776-2778
Author(s):  
Sobia Siddique ◽  
Syed Muhammad Razi Zaidi ◽  
Shahida Maqbool ◽  
Madiha Insha ◽  
Muhammad Abul Hasan Ali ◽  
...  
Keyword(s):  
Blood Group ◽  
Oral Submucous Fibrosis ◽  
Malignant Lesion ◽  
Oral Pathology ◽  
Blood Groups ◽  
P Value ◽  
Blood Group System ◽  
Increased Risk ◽  
Submucous Fibrosis ◽  
B Blood Group

Objective: To assess any association of blood groups with oral submucous fibrosis and if any of the blood group is related with an increased risk for oral submucous fibrosis. Study Design: Comparative study Place and Duration of Study: Department Of Oral Pathology, Fatima Jinnah Dental College & Hospital Karachi, Pakistan from Jan to Dec 2018. Patients and Methods: Total 100 patients were enrolled in the study in which half were cases where oral sub mucous fibrosis had been diagnosed clinically while remaining half were the controls that were involved in the habit of using tobacco/nuts but had no oral pre malignant lesion. For investigation of blood, samples of blood were taken from both the groups. Odd ration and chi-square test was used to analyze data. A p-value of <0.05 was considered statistically significant. Results: Majority of the individuals in experimental group had “B” blood group followed by “O” “AB” and “A” blood groups. Conclusion: This study showed that ABO blood groups have considerable relation with oral submucous fibrosis. Individuals having “B” blood group had 2.18 times increased tendency of having oral submucous fibrosis in contrast with patients who belong to any other blood group. Keywords: ABO blood group system, Oral Submucous fibrosis, Oral lesions, Oral Squamous Cell Carcinoma

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